المؤلفون: Margara, F, Psaras, Y, Wang, ZJ, Schmid, M, Doste, R, Garfinkel, AC, Repetti, GG, Seidman, JG, Seidman, CE, Rodriguez, B, Toepfer, CN, Bueno-Orovio, A

المصدر: Scientific reports. 12(1)

مصطلحات موضوعية: Multidisciplinary, Myosin Heavy Chains, Troponin T, Mutation, Troponin I, Humans, Precision Medicine, Cardiomyopathy, Hypertrophic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c3253082189e3688f61c8ee1c79f9c
https://pubmed.ncbi.nlm.nih.gov/36577774

المؤلفون: Garcia-Pavia, P, Kim, Y, Restrepo-Cordoba, MA, Lunde, IG, Wakimoto, H, Smith, AM, Toepfer, CN, Getz, K, Gorham, J, Patel, P, Ito, K, Willcox, JA, Arany, Z, Li, J, Owens, AT, Govind, R, Nuñez, B, Mazaika, E, Bayes-Genis, A, Walsh, R, Finkelman, B, Lupon, J, Whiffin, N, Serrano, I, Midwinter, W, Wilk, A, Bardaji, A, Ingold, N, Buchan, R, Tayal, U, Pascual-Figal, DA, De Marvao, A, Ahmad, M, Garcia-Pinilla, JM, Pantazis, A, Dominguez, F, John Baksi, A, O'Regan, DP, Rosen, SD, Prasad, SK, Lara-Pezzi, E, Provencio, M, Lyon, AR, Alonso-Pulpon, L, Cook, SA, DePalma, SR, Barton, PJR, Aplenc, R, Seidman, JG, Ky, B, Ware, JS, Seidman, CE

المساهمون: Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España), Wellcome Trust, Medical Research Council (Reino Unido), National Institute for Health Research (Reino Unido), Imperial College London (Reino Unido), Fondation Leducq, British Heart Foundation, National Institutes of Health (Estados Unidos), Howard Hughes Medical Institute, Fundación ProCNIC, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Department of Health, Royal Brompton & Harefield NHS Foundation Trust, Imperial College Healthcare NHS Trust- BRC Funding, Rosetrees Trust, The Academy of Medical Sciences

المصدر: Circulation
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: CARDIOTOXICITY, cardiomyopathies, Adult, Male, Cardiac & Cardiovascular Systems, FAMILIAL DILATED CARDIOMYOPATHY, Antineoplastic Agents, Mice, Transgenic, TITIN, 1117 Public Health and Health Services, Cohort Studies, Mice, Neoplasms, A-BAND TRUNCATION, Animals, Humans, genetics, titin, Prospective Studies, AMERICAN SOCIETY, 1102 Cardiorespiratory Medicine and Haematology, POLYMORPHISMS, Aged, Retrospective Studies, Science & Technology, CONGESTIVE-HEART-FAILURE, MUTATIONS, Genetic Variation, 1103 Clinical Sciences, CHEMOTHERAPY, Middle Aged, medical oncology, drug therapy, Mice, Inbred C57BL, Peripheral Vascular Disease, Cardiovascular System & Hematology, Cardiovascular System & Cardiology, Female, ECHOCARDIOGRAPHY, Cardiomyopathies, Life Sciences & Biomedicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ab94f88417d0f5971f353ebde1cc5ef7
https://hdl.handle.net/10668/13834

المؤلفون: Toepfer, CN, West, TG, Ferenczi, MA

مصطلحات موضوعية: muscle contraction, cardiac muscle, phosphorylation, regulatory light chain, macromolecular substances, musculoskeletal system, force redevelopment

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______900::290858b4d0596dbb9f29d06858724c11
https://bura.brunel.ac.uk/handle/2438/24088

المؤلفون: Psaras Y; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Toepfer CN; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

المصدر: Experimental physiology [Exp Physiol] 2024 Feb; Vol. 109 (2), pp. 175-189. Date of Electronic Publication: 2023 Dec 14.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9002940 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-445X (Electronic) Linking ISSN: 09580670 NLM ISO Abbreviation: Exp Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Muscle, Skeletal*/metabolism , Muscular Dystrophy, Duchenne*/genetics, Humans ; Heart ; Genetic Therapy

المؤلفون: Robinson P; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK. Electronic address: paul.robinson@cardiov.ox.ac.uk., Sparrow AJ; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Psaras Y; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Steeples V; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Simon JN; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Broyles CN; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Chang YF; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Brook FA; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Wang YJ; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Blease A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Zhang X; Agilent Biosciences, Inc., San Diego, CA 92121, USA., Abassi YA; Agilent Biosciences, Inc., San Diego, CA 92121, USA., Geeves MA; Department of Biosciences, University of Kent, Canterbury, UK., Toepfer CN; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK; Department of Genetics, Harvard Medical School, Boston, MA, USA., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK; Department of Cardiology, Oxford University NHS Hospitals Trust, Oxford, UK., Redwood C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK., Daniels MJ; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; BHF Centre of Research Excellence, University of Oxford, Oxford, UK; Department of Cardiology, Oxford University NHS Hospitals Trust, Oxford, UK; Department of Cardiovascular Sciences, University of Manchester, Manchester, UK. Electronic address: matthewdaniels@doctors.org.uk.

المصدر: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2023 Jul; Vol. 180, pp. 44-57. Date of Electronic Publication: 2023 Apr 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells*/metabolism , Myocytes, Cardiac*/metabolism, Animals ; Guinea Pigs ; Humans ; Mice ; Calcium/metabolism ; Coloring Agents/metabolism ; Coloring Agents/pharmacology ; Myocardial Contraction ; Swine

المؤلفون: Venturini G; Department of Genetics, Harvard Medical School, Boston, MA, United States.; Laboratory of Genetics and Molecular Cardiology, University of São Paulo Medical School, São Paulo, Brazil., Alvim JM; Laboratory of Genetics and Molecular Cardiology, University of São Paulo Medical School, São Paulo, Brazil., Padilha K; Laboratory of Genetics and Molecular Cardiology, University of São Paulo Medical School, São Paulo, Brazil., Toepfer CN; Department of Genetics, Harvard Medical School, Boston, MA, United States.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Gorham JM; Department of Genetics, Harvard Medical School, Boston, MA, United States., Wasson LK; Department of Genetics, Harvard Medical School, Boston, MA, United States., Biagi D; LizarBio Therapeutics, Sao Paulo, Brazil., Schenkman S; Department of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, São Paulo, Brazil., Carvalho VM; Division of Research and Development, Fleury Group, São Paulo, SP, Brazil., Salgueiro JS; Division of Research and Development, Fleury Group, São Paulo, SP, Brazil., Cardozo KHM; Division of Research and Development, Fleury Group, São Paulo, SP, Brazil., Krieger JE; Laboratory of Genetics and Molecular Cardiology, University of São Paulo Medical School, São Paulo, Brazil., Pereira AC; Department of Genetics, Harvard Medical School, Boston, MA, United States.; Laboratory of Genetics and Molecular Cardiology, University of São Paulo Medical School, São Paulo, Brazil., Seidman JG; Department of Genetics, Harvard Medical School, Boston, MA, United States., Seidman CE; Department of Genetics, Harvard Medical School, Boston, MA, United States.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.; Howard Hughes Medical Institute, Chevy Chase, MD, United States.

المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Feb 06; Vol. 13, pp. 1098457. Date of Electronic Publication: 2023 Feb 06 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Trypanosoma cruzi*/metabolism , Chagas Cardiomyopathy* , Chagas Disease*/parasitology, Humans ; Myocytes, Cardiac/metabolism ; Immunity, Innate

المؤلفون: Meier AB; First Department of Medicine, Cardiology, Klinikum rechts der Isar, Technical University of Munich, School of Medicine and Health, Munich 81675, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Raj Murthi S; Department of Congenital Heart Defects and Pediatric Cardiology, German Heart Center Munich, Technical University of Munich, School of Medicine and Health, Munich 80636, Germany., Rawat H; First Department of Medicine, Cardiology, Klinikum rechts der Isar, Technical University of Munich, School of Medicine and Health, Munich 81675, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Toepfer CN; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Santamaria G; First Department of Medicine, Cardiology, Klinikum rechts der Isar, Technical University of Munich, School of Medicine and Health, Munich 81675, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Schmid M; Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK., Mastantuono E; Institute of Human Genetics, Helmholtz Zentrum Munich, German Research Center for Environmental Health, Neuherberg 85764, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Schwarzmayr T; Institute of Human Genetics, Helmholtz Zentrum Munich, German Research Center for Environmental Health, Neuherberg 85764, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Berutti R; Institute of Human Genetics, Klinikum rechts der Isar, Technical University of Munich, School of Medicine and Health, Munich 81675, Germany.; Institute of Neurogenomics, Helmholtz Zentrum Munich, German Research Center for Environmental Health, Neuherberg 85764, Germany., Cleuziou J; Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technical University of Munich, Munich 80636, Germany.; INSURE (Institute for Translational Cardiac Surgery), Department of Cardiovascular Surgery, German Heart Center Munich, Technical University of Munich, Munich 80636, Germany., Ewert P; Department of Congenital Heart Defects and Pediatric Cardiology, German Heart Center Munich, Technical University of Munich, School of Medicine and Health, Munich 80636, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Görlach A; Department of Congenital Heart Defects and Pediatric Cardiology, German Heart Center Munich, Technical University of Munich, School of Medicine and Health, Munich 80636, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Klingel K; Institute for Pathology and Neuropathology, Department of Cardiopathology, University Hospital Tuebingen, Tuebingen 72076, Germany., Laugwitz KL; First Department of Medicine, Cardiology, Klinikum rechts der Isar, Technical University of Munich, School of Medicine and Health, Munich 81675, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Seidman CE; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Seidman JG; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Moretti A; First Department of Medicine, Cardiology, Klinikum rechts der Isar, Technical University of Munich, School of Medicine and Health, Munich 81675, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany., Wolf CM; Department of Congenital Heart Defects and Pediatric Cardiology, German Heart Center Munich, Technical University of Munich, School of Medicine and Health, Munich 80636, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich Germany.

المصدر: IScience [iScience] 2021 Dec 09; Vol. 25 (1), pp. 103596. Date of Electronic Publication: 2021 Dec 09 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

المؤلفون: Zhang K; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA., Cloonan PE; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA., Sundaram S; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA., Liu F; State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China., Das SL; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.; Harvard-MIT Program in Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Ewoldt JK; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA., Bays JL; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA., Tomp S; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA., Toepfer CN; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK., Marsiglia JDC; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Gorham J; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Reichart D; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Eyckmans J; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA., Seidman JG; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Seidman CE; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA., Chen CS; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.

المصدر: Science advances [Sci Adv] 2021 Oct 15; Vol. 7 (42), pp. eabh3995. Date of Electronic Publication: 2021 Oct 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Agarwal R; Department of Genetics (R.A., C.N.T., Q.Z., J.G., S.R.D., C.E.S., J.G.S.), Harvard Medical School, Boston, MA., Paulo JA; Department of Cell Biology(J.A.P., S.P.G.), Harvard Medical School, Boston, MA., Toepfer CN; Department of Genetics (R.A., C.N.T., Q.Z., J.G., S.R.D., C.E.S., J.G.S.), Harvard Medical School, Boston, MA.; Radcliffe Department of Medicine (C.N.T.), University of Oxford, United Kingdom.; Wellcome Centre for Human Genetics (C.N.T.), University of Oxford, United Kingdom., Ewoldt JK; Department of Biomedical Engineering, Boston University, MA (J.K.E., S.S., A.C., C.S.C.)., Sundaram S; Department of Biomedical Engineering, Boston University, MA (J.K.E., S.S., A.C., C.S.C.).; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA (S.S., A.C., C.S.C.)., Chopra A; Department of Biomedical Engineering, Boston University, MA (J.K.E., S.S., A.C., C.S.C.).; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA (S.S., A.C., C.S.C.)., Zhang Q; Department of Genetics (R.A., C.N.T., Q.Z., J.G., S.R.D., C.E.S., J.G.S.), Harvard Medical School, Boston, MA., Gorham J; Department of Genetics (R.A., C.N.T., Q.Z., J.G., S.R.D., C.E.S., J.G.S.), Harvard Medical School, Boston, MA., DePalma SR; Department of Genetics (R.A., C.N.T., Q.Z., J.G., S.R.D., C.E.S., J.G.S.), Harvard Medical School, Boston, MA., Chen CS; Department of Biomedical Engineering, Boston University, MA (J.K.E., S.S., A.C., C.S.C.).; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA (S.S., A.C., C.S.C.)., Gygi SP; Department of Cell Biology(J.A.P., S.P.G.), Harvard Medical School, Boston, MA., Seidman CE; Department of Genetics (R.A., C.N.T., Q.Z., J.G., S.R.D., C.E.S., J.G.S.), Harvard Medical School, Boston, MA.; Howard Hughes Medical Institute, Chevy Chase, MD (C.E.S.).; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA (C.E.S.)., Seidman JG; Department of Genetics (R.A., C.N.T., Q.Z., J.G., S.R.D., C.E.S., J.G.S.), Harvard Medical School, Boston, MA.

المصدر: Circulation research [Circ Res] 2021 Sep 17; Vol. 129 (7), pp. 751-766. Date of Electronic Publication: 2021 Aug 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Cardiomyopathies/*genetics , Filamins/*genetics , Lysosomes/*metabolism, Cells, Cultured ; Filamins/metabolism ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism ; Myocardial Contraction ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/physiology ; Sarcomeres/metabolism

المؤلفون: Psaras Y; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (Y.P., F.M., A.J.S., M.S., V.S., C.S.R., H.C.W., P.R., C.N.T.), University of Oxford, United Kingdom., Margara F; Computer Science (F.M., A.B.-O., B.R.), University of Oxford, United Kingdom., Cicconet M, Sparrow AJ, Repetti GG; Genetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA., Schmid M, Steeples V, Wilcox JAL; Genetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA., Bueno-Orovio A; Computer Science (F.M., A.B.-O., B.R.), University of Oxford, United Kingdom., Redwood CS, Watkins HC; Wellcome Centre for Human Genetics (H.C.W., C.N.T.), University of Oxford, United Kingdom., Robinson P; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (Y.P., F.M., A.J.S., M.S., V.S., C.S.R., H.C.W., P.R., C.N.T.), University of Oxford, United Kingdom., Rodriguez B; Computer Science (F.M., A.B.-O., B.R.), University of Oxford, United Kingdom., Seidman JG; Genetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA., Seidman CE; Genetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA.; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA (C.E.S.).; Howard Hughes Medical Institute, Chevy Chase, MD (C.E.S.)., Toepfer CN; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (Y.P., F.M., A.J.S., M.S., V.S., C.S.R., H.C.W., P.R., C.N.T.), University of Oxford, United Kingdom.; Wellcome Centre for Human Genetics (H.C.W., C.N.T.), University of Oxford, United Kingdom.; Genetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA.

المصدر: Circulation research [Circ Res] 2021 Jul 09; Vol. 129 (2), pp. 326-341. Date of Electronic Publication: 2021 May 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Video-Audio Media

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0047103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4571 (Electronic) Linking ISSN: 00097330 NLM ISO Abbreviation: Circ Res Subsets: MEDLINE

مواضيع طبية MeSH: Algorithms* , Calcium Signaling* , High-Throughput Screening Assays* , Image Processing, Computer-Assisted* , Microscopy, Fluorescence*, Calcium/*metabolism , Induced Pluripotent Stem Cells/*metabolism , Myocytes, Cardiac/*metabolism, Animals ; Automation, Laboratory ; Cells, Cultured ; Guinea Pigs ; Humans ; Kinetics ; Mutation, Missense ; Troponin I/genetics ; Troponin I/metabolism ; Workflow