المؤلفون: Mototsugu Ito, Tomasz Wojtkowski, Ronald A. Smulders, Akihiro Yamada, Ronald Goldwater, Akira Koibuchi, Tolga Uz, Sitra Tauscher-Wisniewski, Gerard J. Marek

المصدر: Muscle & Nerve. 65:110-120

مصطلحات موضوعية: Physiology, business.industry, Pharmacology, Placebo, Bioavailability, Cellular and Molecular Neuroscience, Pharmacokinetics, Tolerability, Physiology (medical), Pharmacodynamics, Medicine, Peroxisome proliferator-activated receptor delta, Neurology (clinical), Adverse effect, business, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cbdea70432c6f16acb2f20525a7f7d76
https://doi.org/10.1002/mus.27436

المؤلفون: Eugenii A. Rabiner, Ayla Mansur, Wei Yin, Terry Brown, Graham E. Searle, Tolga Uz, Joy Atienza, Johannes Tauscher, Jeremy M. T. J. Dennison, Jan Passchier, Jingtao Wu, Roger N. Gunn, Grace Chen, Adam J. Schwarz, Yvonne Lewis

المصدر: Neuropsychopharmacology. 47:1405-1412

مصطلحات موضوعية: Pharmacology, Agonist, medicine.drug_class, business.industry, Putamen, Central nervous system, Ventral striatum, Dopaminergic, Binding potential, Human brain, Psychiatry and Mental health, medicine.anatomical_structure, Dopamine, medicine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a44494da2b1fe57c5052a38f0043c386
https://doi.org/10.1038/s41386-021-01204-1

المؤلفون: Amit Desai, Gregory A. Light, Lev Gertsik, Tong Zhu, Paul Maruff, Tolga Uz, Lauren Benner, Ruishan Wu, Gerard J. Marek

المصدر: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 46, iss 6

مصطلحات موضوعية: Psychiatry, Pharmacology, Oncology, Psychomotor function, medicine.medical_specialty, business.industry, Psychology and Cognitive Sciences, Mismatch negativity, Schizoaffective disorder, Placebo, medicine.disease, Medical and Health Sciences, law.invention, Psychiatry and Mental health, Mood, Randomized controlled trial, Tolerability, law, Schizophrenia, Internal medicine, medicine, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea50f3e2fd45a84b8067dde51464766a
https://doi.org/10.1038/s41386-020-00908-0

المؤلفون: Paul Goldsmith, Thomas A. Macek, Tolga Uz, Perry F. Renshaw, Deborah A. Yurgelun-Todd

المصدر: Psychopharmacology

مصطلحات موضوعية: Adult, Male, Adolescent, Phosphodiesterase Inhibitors, medicine.medical_treatment, TAK-063, Placebo, Young Adult, Double-Blind Method, medicine, Clinical endpoint, Humans, Drug Interactions, Ketamine, Antipsychotic, Original Investigation, Pharmacology, Cross-Over Studies, Risperidone, Resting state fMRI, medicine.diagnostic_test, Phosphoric Diester Hydrolases, business.industry, fMRI, Brain, Electroencephalography, Magnetic resonance imaging, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Healthy Volunteers, Pyridazines, Schizophrenia, Anesthesia, Pyrazoles, business, Excitatory Amino Acid Antagonists, BOLD, PDE-10 inhibitor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8377ea952f56a9dae8f4946439112396
https://doi.org/10.1007/s00213-019-05366-1

المؤلفون: Mototsugu, Ito, Sitra, Tauscher-Wisniewski, Ronald A, Smulders, Tomasz, Wojtkowski, Akihiro, Yamada, Akira, Koibuchi, Tolga, Uz, Gerard J, Marek, Ronald D, Goldwater

المصدر: Musclenerve. 65(1)

مصطلحات موضوعية: Adult, Dose-Response Relationship, Drug, Double-Blind Method, Sulfates, Area Under Curve, Imidazoles, Administration, Oral, Humans, PPAR delta, Caproates, Healthy Volunteers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f6f14c70caeea1680b01d375a878d446
https://pubmed.ncbi.nlm.nih.gov/34642949

المؤلفون: Arjan Blokland, Marlies van Duinen, Anke Sambeth, Gezim Lahu, Pim R. A. Heckman, Max Tsai, Jos Prickaerts, Tolga Uz

المساهمون: Section Psychopharmacology, RS: FPN NPPP II, RS: MHeNs - R3 - Neuroscience, Psychiatrie & Neuropsychologie, Promovendi MHN

المصدر: Neurobiology of Aging, 77, 37-43. Elsevier Science

مصطلحات موضوعية: 0301 basic medicine, Cyclopropanes, Aging, Placebo-controlled study, Aminopyridines, Verbal memory, DISEASE, Healthy Aging, 0302 clinical medicine, Cyclic AMP, Aged, 80 and over, Cross-Over Studies, Long-term memory, General Neuroscience, Cognition, EDUCATION, Middle Aged, Stimulation, Chemical, PHOSPHODIESTERASE-4 INHIBITOR, LONG-TERM-MEMORY, Benzamides, Animal studies, medicine.drug, medicine.medical_specialty, NORMATIVE DATA, ROLIPRAM, 03 medical and health sciences, AGE, ENHANCEMENT, Double-Blind Method, Memory, Internal medicine, medicine, Humans, Adverse effect, N-OXIDE, Roflumilast, Aged, Cognition enhancement, Dose-Response Relationship, Drug, business.industry, Verbal Behavior, Crossover study, 030104 developmental biology, Mental Recall, COGNITION, Neurology (clinical), Phosphodiesterase 4 Inhibitors, Geriatrics and Gerontology, CAMP, business, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1917da41ead77469a6e160a7cfeecb16
https://doi.org/10.1016/j.neurobiolaging.2019.01.014

المؤلفون: Tolga Uz, Mitul A. Mehta, Sukhi Shergill, Frank Ogrinc, Lorena Valdearenas, James Gilleen, Max Tsai, Steve C.R. Williams, Yakub Farah, Gez Lahu, Sarah Kerins, Avi Reichenberg, Cate Davison

المصدر: Psychopharmacology
Gilleen, J, Farah, Y, Davison, C, Kerins, S, Valdearenas, L, Uz, T, Lahu, G, Tsai, M, Ogrinc, F, Reichenberg, A, Williams, S C, Mehta, M A & Shergill, S S 2018, ' An experimental medicine study of the phosphodiesterase-4 inhibitor, roflumilast, on working memory-related brain activity and episodic memory in schizophrenia patients ', Psychopharmacology, vol. 0, no. 0, pp. 1-11 . https://doi.org/10.1007/s00213-018-5134-y

مصطلحات موضوعية: Cyclopropanes, Male, Aminopyridines, Audiology, CIAS, Cognition, 0302 clinical medicine, Episodic memory, Original Investigation, Cross-Over Studies, fMRI, Brain, Middle Aged, ‘PDE4 inhibition’, Memory, Short-Term, medicine.anatomical_structure, Schizophrenia, Benzamides, Female, medicine.drug, Adult, medicine.medical_specialty, Memory, Episodic, Prefrontal Cortex, Placebo, behavioral disciplines and activities, ‘Cognitive enhancement’, 03 medical and health sciences, Double-Blind Method, Memory, medicine, Animals, Humans, Roflumilast, Pharmacology, Working memory, business.industry, medicine.disease, 030227 psychiatry, Dorsolateral prefrontal cortex, Phosphodiesterase 4 Inhibitors, PDE4, Verbal memory, Cognition Disorders, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1d51d1938ef9c4ac3e9cd298c03f28
https://doi.org/10.1007/s00213-018-5134-y

المؤلفون: Farah Yakub, Gez Lahu, Tolga Uz, Mitul A. Mehta, Steve C.R. Williams, Sukhi Shergill, James Gilleen, Judith Nottage, Sarah Kerins, Max Tsai, Lorena Valdearenas, Dominic Ffytche, Frank Ogrinc

المصدر: Journal of psychopharmacology (Oxford, England). 35(1)

مصطلحات موضوعية: Oncology, Adult, Cyclopropanes, Male, medicine.medical_specialty, Phosphodiesterase Type 4, Aminopyridines, Electroencephalography, law.invention, 03 medical and health sciences, 0302 clinical medicine, Cognition, Mental Processes, Quality of life, Randomized controlled trial, Double-Blind Method, law, Internal medicine, Medicine, Humans, Pharmacology (medical), Cognitive Dysfunction, Evoked Potentials, Roflumilast, Pharmacology, Psychiatric Status Rating Scales, Cross-Over Studies, medicine.diagnostic_test, business.industry, medicine.disease, 030227 psychiatry, Cyclic Nucleotide Phosphodiesterases, Type 4, Psychiatry and Mental health, Treatment Outcome, Schizophrenia, Benzamides, Female, Phosphodiesterase 4 Inhibitors, Drug Monitoring, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bf23e8532241432f270a1bec2fc67f
https://pubmed.ncbi.nlm.nih.gov/32854568

المؤلفون: Tong Zhu, Lev Gertsik, Ruishan Wu, Amit Desai, Lauren Benner, Gerard J. Marek, Tolga Uz

المصدر: Clinical Pharmacokinetics

مصطلحات موضوعية: Adult, Male, medicine.medical_treatment, Administration, Oral, Pharmacology, Placebo, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Cerebrospinal fluid, Pharmacokinetics, Double-Blind Method, medicine, Distribution (pharmacology), Humans, Pharmacology (medical), Dosing, Original Research Article, Antipsychotic, Randomized Controlled Trials as Topic, Clinical Trials, Phase I as Topic, Dose-Response Relationship, Drug, business.industry, Area under the curve, Middle Aged, medicine.disease, 030227 psychiatry, Psychotic Disorders, Schizophrenia, Area Under Curve, Dopamine Agonists, Benzimidazoles, Female, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6568c081decdcb50d5268196be5d672c
https://pubmed.ncbi.nlm.nih.gov/32533536

المؤلفون: Arjan Blokland, Anke Sambeth, Jos Prickaerts, Pim R. A. Heckman, Tolga Uz, Marlies van Duinen

المساهمون: Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience, Section Psychopharmacology, RS: FPN NPPP II

المصدر: Psychopharmacology
Psychopharmacology, 235(1). Springer

مصطلحات موضوعية: 0301 basic medicine, MECHANISM, Cyclopropanes, Male, Aminopyridines, Stimulation, Gating, Pharmacology, law.invention, 0302 clinical medicine, Randomized controlled trial, law, SCHIZOPHRENIA, PHOSPHODIESTERASE-4 INHIBITORS, Original Investigation, Sensory gating, Electroencephalography, Nausea, Effective dose (pharmacology), Clinical trial, medicine.anatomical_structure, Anesthesia, Benzamides, Evoked Potentials, Auditory, Female, medicine.drug, Adult, Adolescent, AUDITORY-EVOKED POTENTIALS, Vomiting, Sensory system, RATS, 03 medical and health sciences, Young Adult, Double-Blind Method, medicine, Journal Article, SCHIZOTYPAL PERSONALITY, Animals, Humans, Phosphodiesterase, Adverse effect, Roflumilast, RECEPTOR, Dose-Response Relationship, Drug, business.industry, P50, 030104 developmental biology, NEUROPHYSIOLOGICAL BIOMARKERS, COGNITION, Phosphodiesterase 4 Inhibitors, Phosphodiesterase inhibitor, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27a1457e2df97b267ec40e3b77acbfc
http://europepmc.org/articles/PMC5748397