المؤلفون: Markus Mayrhofer, Bram De Laere, Tom Whitington, Peter Van Oyen, Christophe Ghysel, Jozef Ampe, Piet Ost, Wim Demey, Lucien Hoekx, Dirk Schrijvers, Barbara Brouwers, Willem Lybaert, Els Everaert, Daan De Maeseneer, Michiel Strijbos, Alain Bols, Karen Fransis, Steffi Oeyen, Pieter-Jan van Dam, Gert Van den Eynden, Annemie Rutten, Markus Aly, Tobias Nordström, Steven Van Laere, Mattias Rantalainen, Prabhakar Rajan, Lars Egevad, Anders Ullén, Jeffrey Yachnin, Luc Dirix, Henrik Grönberg, Johan Lindberg

المصدر: Genome Medicine, Vol 10, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Circulating tumor DNA, Metastatic prostate cancer, Microsatellite instability, Structural rearrangement, Clonal hematopoiesis, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-018-0595-5; https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/4783b889dd4d4c3c8abf60a59cf0a086

المؤلفون: Ulf de Faire, Yi Lu, Kenneth Caidahl, Lars Lind, Thomas Karlsson, Sara Hägg, Peter Almgren, Susan L. Slager, Yiqiang Zhan, Jie Song, Robert Karlsson, Cecilia M. Lindgren, Nancy L. Pedersen, Xu Chen, Patrik K. E. Magnusson, Tom Whitington, Andrew P. Morris, Jitong Sun, Stefan Gustafsson, Per Svensson, Erik Lorentzen, Jun Su, Mikael C. I. Karlsson, Olle Melander, Erik Ingelsson, Yan Borné, Johan Frostegård, Gunnar Engström, Karin E. Smedby

المصدر: HUMAN MOLECULAR GENETICS
Hum Mol Genet

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Phosphorylcholine, Chronic lymphocytic leukemia, Apoptosis, Genome-wide association study, Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, Antibodies, Article, Epitopes, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, Humans, Allele, Molecular Biology, Genetics (clinical), Aged, Genetic association, biology, Macrophages, Haplotype, General Medicine, Middle Aged, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Lipoproteins, LDL, Core Binding Factor Alpha 3 Subunit, 030104 developmental biology, Haplotypes, Immunoglobulin M, 030220 oncology & carcinogenesis, biology.protein, Female, Genome-Wide Association Study

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdff06a142bc9914d409b8fbaa9239b
https://doi.org/10.1093/hmg/ddy094

المؤلفون: Annemie Rutten, Steven Van Laere, Henrik Grönberg, Peter A. van Dam, Dirk Goossens, Daan De Maeseneer, Mattias Rantalainen, Willem Lybaert, Piet Ost, Steffi Oeyen, Jozef Ampe, Gert Van den Eynden, Jurgen Del Favero, Lien Heyrman, Michiel Strijbos, Barbara Brouwers, Anja Brouwer, Karen Fransis, Peter Van Oyen, Bram De Laere, Wim Demey, Lucien Hoekx, Stefan Sleijfer, Anders Ullén, Christophe Ghysel, Els Everaert, Prabhakar Rajan, Alain Bols, Nick Beije, Ingeborg E. de Kruijff, Jeffrey Yachnin, Markus Mayrhofer, Johan Lindberg, Valerie van Dam, Tom Whitington, Dirk Schrijvers, Luc Dirix

المساهمون: Medical Oncology

المصدر: Clinical cancer research
CLINICAL CANCER RESEARCH
Clinical Cancer Research, 25(6), 1766-1773. American Association for Cancer Research Inc.

مصطلحات موضوعية: EXPRESSION, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, THERAPY, RECOMMENDATIONS, Article, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Circulating tumor cell, MESSENGER-RNA DETECTION, DESIGN, SDG 3 - Good Health and Well-being, Internal medicine, Medicine and Health Sciences, Medicine, Enzalutamide, Clinical significance, Progression-free survival, CLINICAL-SIGNIFICANCE, business.industry, Proportional hazards model, 2ND-LINE ABIRATERONE, medicine.disease, CIRCULATING TUMOR-CELLS, Androgen receptor, TRIALS, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Predictive value of tests, SURVIVAL, Human medicine, business

وصف الملف: pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7775cd4b741e99e3013042119f7c15c7
https://hdl.handle.net/10067/1585390151162165141

المؤلفون: Johan Lindberg, Robert Karlsson, Tom Whitington, Ping Gao, Daniel Klevebring, Henrik Grönberg, Silvia Halim, David E. Neal, Anne Y. Warren, Mark J Dunning, Lars Egevad, Fredrik Wiklund, Ilaria Svezia, Wei Song, Gong-Hong Wei, Yuehong Yang, Alastair D. Lamb, Ian G. Mills, Helen Ross-Adams

المصدر: Nature Genetics. 48:387-397

مصطلحات موضوعية: Male, 0301 basic medicine, CCCTC-Binding Factor, Quantitative Trait Loci, Single-nucleotide polymorphism, Genome-wide association study, Locus (genetics), Genomics, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, Prostate cancer, Risk Factors, Genetics, medicine, Humans, Gene Regulatory Networks, Genetic Predisposition to Disease, Gene, Binding Sites, Base Sequence, Prostatic Neoplasms, Sequence Analysis, DNA, medicine.disease, Biomarker (cell), Gene Expression Regulation, Neoplastic, Repressor Proteins, 030104 developmental biology, Expression quantitative trait loci, Genome-Wide Association Study, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0904cc42bd9f8397ed5fb37e24bb525
https://doi.org/10.1038/ng.3523

المؤلفون: Peter Van Oyen, Wim Demey, Els Everaert, Steven Van Laere, Daan De Maeseneer, Gert Van den Eynden, Lars Egevad, Michiel Strijbos, Karen Fransis, Alain Bols, Johan Lindberg, Mattias Rantalainen, Willem Lybaert, Piet Ost, Annemie Rutten, Dirk Schrijvers, Tom Whitington, Anders Ullén, Barbara Brouwers, Steffi Oeyen, Luc Dirix, Markus Aly, Prabhakar Rajan, Peter A. van Dam, Lucien Hoekx, Christophe Ghysel, Jozef Ampe, Tobias Nordström, Henrik Grönberg, Bram De Laere, Jeffrey Yachnin, Markus Mayrhofer

المصدر: Genome Medicine
Genome Medicine, Vol 10, Iss 1, Pp 1-13 (2018)
GENOME MEDICINE
Genome medicine

مصطلحات موضوعية: 0301 basic medicine, Male, lcsh:Medicine, chemistry.chemical_compound, Prostate cancer, Metastatic prostate cancer, 0302 clinical medicine, Circulating tumor cell, Medicine and Health Sciences, Genetics (clinical), Aged, 80 and over, Gene Rearrangement, biology, 2ND-LINE ABIRATERONE, Genomics, OPEN-LABEL, TISSUE ACQUISITION, Retinoblastoma Binding Proteins, Cell-free fetal DNA, Receptors, Androgen, 030220 oncology & carcinogenesis, Structural rearrangement, Molecular Medicine, Microsatellite, Clonal hematopoiesis, ENZALUTAMIDE, lcsh:QH426-470, Ubiquitin-Protein Ligases, INCREASED SURVIVAL, Structural variation, 03 medical and health sciences, MESSENGER-RNA DETECTION, Genetics, medicine, Enzalutamide, PTEN, Humans, CLINICAL-SIGNIFICANCE, Molecular Biology, Gene, Aged, Whole genome sequencing, Circulating tumor DNA, MUTATIONS, Research, lcsh:R, BONE-MARROW BIOPSY, PTEN Phosphohydrolase, Microsatellite instability, Prostatic Neoplasms, medicine.disease, DNA Fingerprinting, CIRCULATING TUMOR-CELLS, Hematopoiesis, instability, lcsh:Genetics, 030104 developmental biology, chemistry, biology.protein, Cancer research, Human medicine, Tumor Suppressor Protein p53

وصف الملف: application/pdf; pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11effbe8e91743dd8c5e8ad071584a0a
https://pubmed.ncbi.nlm.nih.gov/30458854

المؤلفون: Cezary Cybulski, Rosalind A. Eeles, Douglas F. Easton, Robert Szulkin, Nora Pashayan, Timothy J. Key, B. E. Henderson, G.G. Giles, Hardev Pandha, Jenny L Donovan, Zsofia Kote-Jarai, Henrik Grönberg, Jong Y. Park, Johanna Schleutker, Kenneth Muir, Melissa C. Southey, Fredrick R. Schumacher, Manuel Luedeke, Markus Aly, David E. Neal, Paul D.P. Pharoah, Ruth C. Travis, Børge G. Nordestgaard, Jyotsna Batra, D J Schaid, Fredrik Wiklund, Judith A. Clements, Amanda B. Spurdle, Katja Butterbach, Lisa A. Cannon-Albright, Janet L. Stanford, Kathleen Herkommer, Adam S. Kibel, W. Vogel, Wojciech Kluźniak, Vanio Mitev, Paula Paulo, Liesel M. FitzGerald, Hermann Brenner, T A Sellers, Shannon K. McDonnell, Tammela Tlj., Lin H-Y., Freddie C. Hamdy, Ali Amin Al Olama, Jan Lubinski, Manuel R. Teixeira, C. Slavov, S. N. Thibodeau, Tom Whitington, C. Stegmaier, Andrzej M. Kierzek, Agnieszka Michael, Christiane Maier, Christopher A. Haiman, Sofia Maia, Khaw K-T., Tiina Wahlfors, Martin Eklund, Radka Kaneva, Sara Benlloch

المصدر: The Prostate. 75:1467-1474

مصطلحات موضوعية: Linkage disequilibrium, education.field_of_study, business.industry, Urology, Population, Area under the curve, Disease, Bioinformatics, medicine.disease, Prostate cancer, Oncology, Genetic marker, Cohort, Genetic variation, Medicine, business, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a3bdc3ed21f90505214d096575c0de5c
https://doi.org/10.1002/pros.23037

المؤلفون: Bettina Kulle Andreassen, Wenche Kristiansen, Trine B. Rounge, Tom Grotmol, Fredrik Wiklund, Patrik K. E. Magnusson, Robert Karlsson, Tom Whitington, Clare Turnbull, Sophie D. Fosså, Hans-Olov Adami, Trine B. Haugen

المصدر: Human Molecular Genetics. 24:4138-4146

مصطلحات موضوعية: Genetic Markers, Male, Genotyping Techniques, Testicular Germ Cell Tumor, Single-nucleotide polymorphism, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, Testicular Neoplasms, Cell Line, Tumor, Genetics, medicine, Humans, Genetic Predisposition to Disease, Molecular Biology, Gene, Genetics (clinical), Sweden, Norway, NF-kappa B, Chromosome, General Medicine, Neoplasms, Germ Cell and Embryonal, HNF1B Gene, Logistic Models, medicine.anatomical_structure, Genetic Loci, Genetic marker, Case-Control Studies, Disease Progression, Chromosomes, Human, Pair 19, Germ cell, Chromosomes, Human, Pair 17, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b745c09cbe4573c3006dfedd95952211
https://doi.org/10.1093/hmg/ddv129

المؤلفون: Peter Wiklund, Brett Delahunt, Johan Lindberg, Markus Mayrhofer, Tom Whitington, Hemamali Samaratunga, Amanda H. Seipel, Henrik Grönberg, Lars Egevad

المصدر: Human pathology. 69

مصطلحات موضوعية: 0301 basic medicine, Biochemical recurrence, Male, Pathology, medicine.medical_specialty, DNA Copy Number Variations, Somatic cell, medicine.medical_treatment, DNA Mutational Analysis, Gene Dosage, Acinar adenocarcinoma, Disease, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, INDEL Mutation, Prostate, medicine, Biomarkers, Tumor, Humans, Genetic Predisposition to Disease, Neoplasm Invasiveness, Aged, Neoplasm Staging, Prostatectomy, Gene Expression Profiling, Prostatic Neoplasms, Middle Aged, medicine.disease, Tumor Burden, Carcinoma, Ductal, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, medicine.anatomical_structure, Phenotype, 030220 oncology & carcinogenesis, Adenocarcinoma, Neoplasm Grading, Transcriptome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d055d5daf49606366eb078f9f6c87d4
https://pubmed.ncbi.nlm.nih.gov/28457729

المؤلفون: Jussi Taipale, Arttu Jolma, Yuehong Yang, Ping Gao, Johan Lindberg, Ruizhu Lin, Qilai Huang, Jian Yan, Matti Annala, Robert Szulkin, Kai Zhang, Markku H. Vaarala, Jianfeng Xu, Tom Whitington, Fredrik Wiklund, Jielin Sun, Matti Nykter, Gong-Hong Wei, Marja-Riitta Väisänen, Lars Egevad, Aki Manninen, Tapio Visakorpi

المصدر: Nature Genetics. 46:126-135

مصطلحات موضوعية: Male, Chromatin Immunoprecipitation, Genotype, Molecular Sequence Data, Electrophoretic Mobility Shift Assay, Regulatory Factor X Transcription Factors, Single-nucleotide polymorphism, Biology, Real-Time Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Metastasis, Cohort Studies, Prostate cancer, Genetics, medicine, Humans, Genetic Predisposition to Disease, Cloning, Molecular, RNA, Small Interfering, Allele, Enhancer, Finland, Homeodomain Proteins, Sweden, Regulation of gene expression, Base Sequence, Chromatin binding, Chromosome Mapping, Prostatic Neoplasms, Sequence Analysis, DNA, medicine.disease, Chromatin, 3. Good health, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Tumor progression, Cancer research, Chromosomes, Human, Pair 6, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cbd558c641098dbab1070d9b5272c6
https://doi.org/10.1038/ng.2862

المؤلفون: Jarkko Toivonen, Jussi Taipale, Arttu Jolma, Jian Yan, Nicholas M. Luscombe, Mikko Taipale, Ekaterina Morgunova, Kimmo Palin, Kazuhiro R. Nitta, Tom Whitington, Patrick Lemaire, Martin Enge, Timothy P. Hughes, Esko Ukkonen, Teemu Kivioja, Gong-Hong Wei, Pasi Rastas, Renaud Vincentelli, Juan M. Vaquerizas

المصدر: Cell. 152(1-2):327-339

مصطلحات موضوعية: Chromatin Immunoprecipitation, Biology, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Phylogenetics, Animals, Humans, Gene, Transcription factor, Phylogeny, 030304 developmental biology, Genetics, 0303 health sciences, Biochemistry, Genetics and Molecular Biology(all), SELEX Aptamer Technique, fungi, DNA, Markov Chains, ChIP-sequencing, chemistry, Chromatin immunoprecipitation, 030217 neurology & neurosurgery, Systematic evolution of ligands by exponential enrichment, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9820ef8889f379d9f623e43f3f37fcd6