المؤلفون: Matthew A. Sleeman, Philip Newton, Brian Naiman, Katherine A. Vousden, Anja Pomowski, James A. Huntington, Clare Murray, Isabelle de Mendez, Tristan J. Vaughan, Alan M. Carruthers, Jane Connor, Daniel J. D. Johnson, Strain Martin D, Patrick Dufner, Tomas Lundqvist, Trevor Wilkinson, Philip R. Mallinder, Bojana Popovic, Lynne Murray, David C. Lowe

المساهمون: Popovic, Bojana [0000-0002-0756-5149], Apollo - University of Cambridge Repository

المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
'Scientific Reports ', vol: 9, pages: 1605-1-1605-12 (2019)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Proteases, Protein Conformation, medicine.medical_treatment, lcsh:Medicine, Serpin, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Antibody Specificity, Fibrinolysis, Plasminogen Activator Inhibitor 1, medicine, Animals, Humans, Amino Acid Sequence, lcsh:Science, Serine protease, Urokinase, Multidisciplinary, biology, Chemistry, lcsh:R, Antibodies, Neutralizing, Cell biology, Rats, 030104 developmental biology, Plasminogen activator inhibitor-1, biology.protein, Vitronectin, lcsh:Q, Plasminogen activator, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3301fff9d7d8f383ecad0b4191cca81
http://europepmc.org/articles/PMC6367345

المؤلفون: Tomas Lundqvist, Stewart L. Fisher, Gunther Kern, Rutger H. A. Folmer, Yafeng Xue, D. Trevor Newton, Thomas A. Keating, Richard A. Alm, Boudewijn L. M. de Jonge

المصدر: Nature, Nature. 447(7146):817-822

الإتاحة: https://ideas.repec.org/a/nat/nature/v447y2007i7146d10.1038_nature05689.html

المؤلفون: Tomas Lundqvist, Douglas B. Jordan, Ylva Lindqvist, James J. Steffens, Tatyana Sandalova, Gregory S. Basarab, Zdzislaw Wawrzak

المصدر: Proteins: Structure, Function, and Genetics. 35:425-439

مصطلحات موضوعية: Enzyme complex, biology, Hydrogen bond, medicine.drug_class, Chemistry, Stereochemistry, Active site, Carboxamide, Lyase, Biochemistry, Crystallography, chemistry.chemical_compound, Structural Biology, Amide, medicine, Side chain, biology.protein, Molecular Biology, Scytalone dehydratase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::263b9e735dfaf1abd02a21fd328e6541
https://doi.org/10.1002/(sici)1097-0134(19990601)35:4<425::aid-prot6>3.0.co;2-1

المؤلفون: James J. Steffens, Beverly R Pfrogner, Tomas Lundqvist, Gregory S. Basarab, Rand S. Schwartz, Zdzislaw Wawrzak, Douglas B. Jordan

المصدر: Pesticide Science. 55:277-280

مصطلحات موضوعية: chemistry.chemical_classification, biology, Stereochemistry, Chemistry, Substrate (chemistry), Active site, Applied Microbiology and Biotechnology, Plant disease, Enzyme catalysis, Elimination reaction, Enzyme, biology.protein, Site-directed mutagenesis, Scytalone dehydratase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1cd408375aeade9783d1c8570c02324b
https://doi.org/10.1002/(sici)1096-9063(199903)55:3<277::aid-ps893>3.0.co;2-1

المؤلفون: Tomas Lundqvist, Gunter Schneider

المصدر: Biochemistry. 30:904-908

مصطلحات موضوعية: Coordination sphere, biology, Stereochemistry, Chemistry, Rhodospirillum rubrum, Active site, Crystal structure, biology.organism_classification, Biochemistry, Protein structure, biology.protein, Binding site, Ternary complex, Protein ligand

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::24729f52297187c9032fb0f8bd39895d
https://doi.org/10.1021/bi00218a004

المؤلفون: Alexander Satz, Lawrence Macpherson, Gregory S. Basarab, Bolin Geng, Ekundayo Osimboni, Pamela Hill, Charles J. Eyermann, Janelle Comita-Prevoir, Madhusudhan Reddy Gowravaram, George B. Mullen, Tomas Lundqvist, Marshall Morningstar, Andrew Kiely, James T. Loch

المصدر: Bioorganicmedicinal chemistry letters. 19(3)

مصطلحات موضوعية: Chemistry, Pharmaceutical, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Plasma protein binding, Muri, Biochemistry, Binding, Competitive, Helicobacter Infections, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Non-competitive inhibition, Anti-Infective Agents, Drug Discovery, Structure–activity relationship, Glutamate racemase, Animals, Humans, Amines, Molecular Biology, Antibacterial agent, Amino Acid Isomerases, chemistry.chemical_classification, biology, Helicobacter pylori, Organic Chemistry, Enzyme, chemistry, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Dimerization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569ca10e683562576800e405bb8042c7
https://pubmed.ncbi.nlm.nih.gov/19097892

المؤلفون: Brian Noonan, Randy Petrichko, Peter Doig, Bolin Geng, Elise Gorseth, Gloria Anne Breault, Tomas Lundqvist, Charles J. Eyermann, Janelle Comita-Prevoir

المصدر: Bioorganicmedicinal chemistry letters. 18(15)

مصطلحات موضوعية: Staphylococcus aureus, Stereochemistry, Gram-positive bacteria, Clinical Biochemistry, Enterococcus faecium, Molecular Conformation, Pharmaceutical Science, Isomerase, Muri, Crystallography, X-Ray, Gram-Positive Bacteria, Biochemistry, Structure-Activity Relationship, Drug Discovery, Enterococcus faecalis, Glutamate racemase, Combinatorial Chemistry Techniques, Purine metabolism, Molecular Biology, Antibacterial agent, Amino Acid Isomerases, chemistry.chemical_classification, biology, Molecular Structure, Chemistry, Organic Chemistry, biology.organism_classification, Anti-Bacterial Agents, Enzyme, Purines, Molecular Medicine, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5372b4655adec951d7ef19416d0d9f1d
https://pubmed.ncbi.nlm.nih.gov/18614367

المؤلفون: Gunter Schneider, Tomas Lundqvist, Ylva Lindqvist

المصدر: Journal of Molecular Biology. 211:989-1008

مصطلحات موضوعية: Models, Molecular, Macromolecular Substances, Protein Conformation, Stereochemistry, Ribulose-Bisphosphate Carboxylase, Molecular Sequence Data, Staggered conformation, Rhodospirillum rubrum, Protein structure, X-Ray Diffraction, Structural Biology, Amino Acid Sequence, Molecular Biology, Peptide sequence, Protein secondary structure, chemistry.chemical_classification, biology, Hydrogen bond, Active site, Hydrogen Bonding, biology.organism_classification, Amino acid, Crystallography, chemistry, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c71503ae55de776e8528a43a685f0be
https://doi.org/10.1016/0022-2836(90)90088-4

المؤلفون: Rutger H. A. Folmer, Boudewijn L. M. de Jonge, Thomas A. Keating, Gunther Kern, Yafeng Xue, D. Trevor Newton, Richard A. Alm, Tomas Lundqvist, Stewart L. Fisher

المصدر: Nature. 447(7146)

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Allosteric regulation, Isomerase, Biology, Crystallography, X-Ray, chemistry.chemical_compound, Structure-Activity Relationship, Biosynthesis, Allosteric Regulation, Escherichia coli, Glutamate racemase, Enzyme Inhibitors, Amino Acid Isomerases, chemistry.chemical_classification, Multidisciplinary, Bacteria, Helicobacter pylori, Drug discovery, Glutamate receptor, Recombinant Proteins, Anti-Bacterial Agents, Kinetics, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Allosteric Site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6320775373e356e41e5af546419442a
https://pubmed.ncbi.nlm.nih.gov/17568739

المؤلفون: Tomas, Lundqvist

المصدر: Current opinion in drug discoverydevelopment. 8(4)

مصطلحات موضوعية: Pharmacology, Magnetic Resonance Spectroscopy, Pharmaceutical Preparations, Drug Design, Biophysics, Drug Evaluation, Preclinical, Animals, Humans, Computer Simulation, Biosensing Techniques, Calorimetry, Crystallography, X-Ray, Biophysical Phenomena

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0f36998c76921b4b91c14bab1ecdcc71
https://pubmed.ncbi.nlm.nih.gov/16022188