المؤلفون: Cheng Z; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK., Ennis DP; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK., Lu B; Department of Cell and Developmental Biology, University College London, London, UK., Mirza HB; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK., Sokota C; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, UK., Kaur B; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, UK., Singh N; Department of Pathology, Barts Healthcare NHS Trust, London, UK., Le Saux O; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK., Russo G; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK., Giannone G; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK., Tookman LA; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK., Krell J; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK., Barnes C; Department of Cell and Developmental Biology, University College London, London, UK., McDermott J; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, UK., McNeish IA; Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London, UK.

المصدر: The Journal of pathology [J Pathol] 2024 Sep; Vol. 264 (1), pp. 42-54. Date of Electronic Publication: 2024 Jul 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE

مواضيع طبية MeSH: Ovarian Neoplasms*/genetics , Ovarian Neoplasms*/pathology , Cystadenocarcinoma, Serous*/genetics , Cystadenocarcinoma, Serous*/pathology , Fallopian Tube Neoplasms*/genetics , Fallopian Tube Neoplasms*/pathology , Tumor Suppressor Protein p53*/genetics, Humans ; Female ; Carcinoma in Situ/genetics ; Carcinoma in Situ/pathology ; Neoplasm Grading ; DNA Copy Number Variations ; Mutation ; Genomics/methods ; Whole Genome Sequencing ; Ploidies ; Middle Aged ; Biomarkers, Tumor/genetics ; Disease Progression

المؤلفون: Cheng Z; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, United Kingdom., Mirza H; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, United Kingdom., Ennis DP; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, United Kingdom., Smith P; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Morrill Gavarró L; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Sokota C; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, United Kingdom., Giannone G; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, United Kingdom.; Department of Oncology, University of Turin, Turin, Italy., Goranova T; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Bradley T; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Piskorz A; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Lockley M; Centre for Cancer Cell and Molecular Biology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Kaur B; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, United Kingdom., Singh N; Department of Pathology, Barts Healthcare NHS Trust, London, United Kingdom., Tookman LA; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, United Kingdom., Krell J; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, United Kingdom., McDermott J; Department of Pathology, University College London Hospital NHS Trust, London, United Kingdom., Macintyre G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Markowetz F; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Brenton JD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., McNeish IA; Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, United Kingdom.

مؤلفون مشاركون: BriTROC-1 Investigators

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Jul 01; Vol. 28 (13), pp. 2911-2922.

نوع المنشور: Research Support, Non-U.S. Gov't; Journal Article

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Ovarian Neoplasms*/genetics , Ovarian Neoplasms*/pathology, Carcinoma, Ovarian Epithelial ; Female ; Genomics ; High-Throughput Nucleotide Sequencing ; Humans ; Middle Aged ; Mutation

المؤلفون: Walton J; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom. Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Blagih J; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Ennis D; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Leung E; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Dowson S; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Farquharson M; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Tookman LA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Orange C; Department of Pathology, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Athineos D; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Mason S; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Stevenson D; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Blyth K; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Strathdee D; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Balkwill FR; Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Vousden K; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Lockley M; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., McNeish IA; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom. Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom. iain.mcneish@glasgow.ac.uk.

المصدر: Cancer research [Cancer Res] 2016 Oct 15; Vol. 76 (20), pp. 6118-6129. Date of Electronic Publication: 2016 Aug 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal*, BRCA2 Protein/*physiology , CRISPR-Cas Systems/*physiology , Cystadenocarcinoma, Serous/*etiology , Ovarian Neoplasms/*etiology , Tumor Suppressor Protein p53/*physiology, Animals ; BRCA2 Protein/genetics ; Cell Line, Tumor ; Cystadenocarcinoma, Serous/drug therapy ; Exome ; Female ; Gene Editing ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/genetics ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use ; Tumor Microenvironment ; Tumor Suppressor Protein p53/genetics

المؤلفون: Tookman LA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Browne AK; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Connell CM; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Bridge G; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Ingemarsdotter CK; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Dowson S; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Shibata A; Advanced Scientific Research Leaders Development Unit, Gunma University, Maebashi, Gunma, Japan., Lockley M; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Martin SA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., McNeish IA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom. Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom. Iain.mcneish@glasgow.ac.uk.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2016 Jan; Vol. 14 (1), pp. 44-55. Date of Electronic Publication: 2015 Oct 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Homologous Recombination*, Adenoviridae/*physiology , BRCA2 Protein/*metabolism , Ovarian Neoplasms/*metabolism , Rad51 Recombinase/*metabolism, Adenoviridae/genetics ; Adenovirus E2 Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cisplatin/pharmacology ; Female ; Genetic Vectors/pharmacology ; Humans ; Oncolytic Virotherapy ; Virus Replication

المؤلفون: Browne A; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Tookman LA; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Ingemarsdotter CK; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Bouwman RD; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Pirlo K; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., Wang Y; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom., McNeish IA; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom. Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Lockley M; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, United Kingdom. m.lockley@qmul.ac.uk.

المصدر: Cancer research [Cancer Res] 2015 Jul 15; Vol. 75 (14), pp. 2811-21. Date of Electronic Publication: 2015 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Adenoviridae/*immunology , Anti-Inflammatory Agents/*pharmacology , Inflammation/*prevention & control , Integrin beta3/*metabolism , Oncolytic Virotherapy/*adverse effects , Oncolytic Viruses/*immunology , Ovarian Neoplasms/*therapy , Peptides, Cyclic/*pharmacology, Adenoviridae/drug effects ; Animals ; Anti-Inflammatory Agents/therapeutic use ; Antineoplastic Agents/immunology ; Antineoplastic Agents/therapeutic use ; Cells, Cultured ; Combined Modality Therapy ; Female ; Humans ; Integrin beta3/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Nude ; Oncolytic Viruses/drug effects ; Ovarian Neoplasms/immunology ; Ovarian Neoplasms/pathology ; Peptides, Cyclic/therapeutic use ; Xenograft Model Antitumor Assays

المؤلفون: Ingemarsdotter CK; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Tookman LA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Browne A; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Pirlo K; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Cutts R; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Chelela C; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Khurrum KF; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Leung EY; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Dowson S; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Webber L; Cancer Research UK and UCL Clinical Trials Centre, London, UK., Khan I; Cancer Research UK and UCL Clinical Trials Centre, London, UK., Ennis D; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Syed N; Division of Brain Sciences, Faculty of Medicine, Imperial College, London, UK., Crook TR; Dundee Cancer Centre, University of Dundee, Ninewells Hospital, Dundee, UK., Brenton JD; Cancer Research UK Cambridge Institute, Cambridge, UK., Lockley M; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., McNeish IA; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Electronic address: iain.mcneish@glasgow.ac.uk.

المصدر: Molecular oncology [Mol Oncol] 2015 Apr; Vol. 9 (4), pp. 791-805. Date of Electronic Publication: 2014 Dec 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Adenoviridae/*metabolism , Cell Cycle Checkpoints/*drug effects , Coxsackie and Adenovirus Receptor-Like Membrane Protein/*metabolism , Drug Resistance, Neoplasm/*drug effects , Oncolytic Viruses/*metabolism , Paclitaxel/*pharmacology , Up-Regulation/*drug effects, Animals ; Cell Line, Tumor ; Cytokines/metabolism ; Female ; Histones/metabolism ; Humans ; Inflammation Mediators/metabolism ; Mice, Nude ; Ovarian Neoplasms/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Xenograft Model Antitumor Assays

المؤلفون: Young AM; Barts Cancer Institute, Queen Mary University of London, London, UK., Archibald KM, Tookman LA, Pool A, Dudek K, Jones C, Williams SL, Pirlo KJ, Willis AE, Lockley M, McNeish IA

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2012 Sep; Vol. 20 (9), pp. 1676-88. Date of Electronic Publication: 2012 Jun 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Protein Biosynthesis*, Adenoviruses, Human/*genetics , Oncolytic Viruses/*genetics , Ovarian Neoplasms/*therapy , RNA, Viral/*metabolism , Viral Nonstructural Proteins/*genetics, Adaptive Immunity ; Adenoviruses, Human/immunology ; Animals ; Cell Line, Tumor ; Eukaryotic Initiation Factor-2/genetics ; Eukaryotic Initiation Factor-2/metabolism ; Female ; Gene Expression ; Humans ; Mice ; Oncolytic Viruses/immunology ; Ovarian Neoplasms/immunology ; Ovarian Neoplasms/pathology ; Ovary/drug effects ; Ovary/immunology ; Ovary/pathology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Viral/genetics ; Ribosomes/genetics ; Ribosomes/metabolism ; Species Specificity ; Viral Nonstructural Proteins/metabolism ; Virus Replication/genetics

المؤلفون: Connell CM; Centre for Molecular Oncology and Imaging, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom., Shibata A, Tookman LA, Archibald KM, Flak MB, Pirlo KJ, Lockley M, Wheatley SP, McNeish IA

المصدر: The Journal of clinical investigation [J Clin Invest] 2011 Apr; Vol. 121 (4), pp. 1283-97. Date of Electronic Publication: 2011 Mar 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Oncolytic Virotherapy*, Cell Cycle Proteins/*metabolism , Oncolytic Viruses/*genetics , Oncolytic Viruses/*physiology , Ovarian Neoplasms/*therapy , Protein Kinases/*metabolism , Protein Serine-Threonine Kinases/*metabolism, Animals ; Ataxia Telangiectasia Mutated Proteins ; Cell Line, Tumor ; Checkpoint Kinase 1 ; DNA Repair ; DNA Replication ; Female ; Humans ; Mice ; Mice, Nude ; Mutation ; Neoplasm Transplantation ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Signal Transduction ; Transplantation, Heterologous ; cdc25 Phosphatases/metabolism