نتائج البحث - "Toops Dana S"

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كتاب إلكتروني

Design, Synthesis, and Evaluation of Novel Oxazolidinone Antibacterial Agents Active Against Multidrug-Resistant Bacteria

المؤلفون: Barbachyn, Michael R., Brickner, Steven J., Gadwood, Robert C., Garmon, Stuart A., Grega, Kevin C., Hutchinson, Douglas K., Munesada, Kiyotaka, Reischer, Robert J., Taniguchi, Mikio, Thomasco, Lisa M., Toops, Dana S., Yamada, Hiromi, Ford, Charles W., Zurenko, Gary E.

المساهمون: Rosen, Barry P., editor^Aff1, Mobashery, Shahriar, editor^Aff1

المصدر: Resolving the Antibiotic Paradox : Progress in Understanding Drug Resistance and Development of New Antibiotics. 456:219-238

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Identification of Phenylisoxazolines as Novel and Viable Antibacterial Agents Active against Gram-Positive Pathogens

المصدر: Journal of Medicinal Chemistry. 46:284-302

مصطلحات موضوعية: Male, Staphylococcus aureus, medicine.drug_class, Biological Availability, Carboxamide, Microbial Sensitivity Tests, In Vitro Techniques, Crystallography, X-Ray, Gram-Positive Bacteria, Chemical synthesis, Piperazines, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, In vivo, Drug Resistance, Bacterial, Drug Discovery, Benzene Derivatives, medicine, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Structure–activity relationship, Antibacterial agent, Chemistry, Stereoisomerism, Isoxazoles, Staphylococcal Infections, Combinatorial chemistry, In vitro, Anti-Bacterial Agents, Rats, Biochemistry, Linezolid, Hepatocytes, Molecular Medicine, Antibacterial activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b367ff99342ae88e0043e780292f449
https://doi.org/10.1021/jm020248u

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Synthesis and antibacterial activity of new tropone-substituted phenyloxazolidinone antibacterial agents 2. Modification of the phenyl ring — the potentiating effect of fluorine substitution on in vivo activity

المؤلفون: Betty H. Yagi, Suzanne E. Glickman, Susan K. Hendges, Ford Charles W, Toops Dana S, Jonda D. Schaadt, Barbachyn Michael R, Douglas Stapert, Kevin C. Grega, Jerry M. Buysse, Judith C. Hamel, James O. Kilburn, Gary E. Zurenko, William F. Demyan

المصدر: Bioorganic & Medicinal Chemistry Letters. 6:1009-1014

مصطلحات موضوعية: Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, chemistry.chemical_element, Ring (chemistry), Biochemistry, Combinatorial chemistry, In vitro, chemistry.chemical_compound, Meta, chemistry, In vivo, Drug Discovery, Fluorine, Molecular Medicine, Tropone, Antibacterial activity, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f0dd928cb5886649f84d91fbdc7e4276
https://doi.org/10.1016/0960-894x(96)00155-2

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Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity

المؤلفون: Sally P. Klemens, Toops Dana S, James O. Kilburn, Susan K. Hendges, Ford Charles W, S. E. Glickman, Gary E. Zurenko, Kevin C. Grega, Steven J. Brickner, Michael H. Cynamon, Hutchinson Douglas K, Barbachyn Michael R

المصدر: Journal of Medicinal Chemistry. 39:680-685

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd36c5010853b90f6315fcfa170f5c2
https://doi.org/10.1021/jm950956y

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Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

المؤلفون: Susan K. Hendges, Toops Dana S, Hutchinson Douglas K, Manninen Peter Rudolph, Barbachyn Michael R, Gary E. Zurenko, Stuart A. Garmon, Steven J. Brickner, Ford Charles W, Kevin C. Grega, Debra A. Ulanowicz

المصدر: Journal of Medicinal Chemistry. 39:673-679

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aabb6b3bba82a4a3a9cb3b1862302a7
https://doi.org/10.1021/jm9509556

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6

Efficient synthesis of 1-(trialkylstannyl)- and 1-(triarylstannyl)bicyclo[1.1.1]pentanes

المؤلفون: Toops Dana S, Barbachyn Michael R

المصدر: The Journal of Organic Chemistry. 58:6505-6508

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Bicyclic molecule, Organic Chemistry, Organic chemistry, Pentanes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1a95a4479f19d496e323a558f8350e72
https://doi.org/10.1021/jo00075a063

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U-87947E, a protein quinolone antibacterial agent incorporating a bicyclo[1.1.1]pent-1-yl (BCP) subunit

المؤلفون: Raymond J. Reid, Gary E. Zurenko, Ronda D. Schaadt, Barbachyn Michael R, John W. Allison, Toops Dana S, Hutchinson Douglas K, Betty H. Yagi

المصدر: Bioorganic & Medicinal Chemistry Letters. 3:671-676

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d473c3ab37e1a7576f9f4b87c210bbc6
https://doi.org/10.1016/s0960-894x(01)81251-8

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ChemInform Abstract: U-87947E (I), a Potent Quinolone Antibacterial Agent Incorporating a Bicyclo(1.1.1)pent-1-yl (BCP) Subunit

المؤلفون: Ronda D. Schaadt, Betty H. Yagi, R. J. Reid, J. W. Allison, Gary E. Zurenko, Toops Dana S, Barbachyn Michael R, Hutchinson Douglas K

المصدر: ChemInform. 26

مصطلحات موضوعية: Bicyclic molecule, medicine.drug_class, Stereochemistry, Chemistry, Protein subunit, medicine, General Medicine, Quinolone, Antibacterial agent

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::96cb677bcc0b692dfb7e64777b527ce6
https://doi.org/10.1002/chin.199508193

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ChemInform Abstract: Synthesis and Antibacterial Activity of New Tropone-Substituted Phenyloxazolidinone Antibacterial Agents. Part 1. Identification of Leads and Importance of the Tropone Substitution Pattern

المؤلفون: Betty H. Yagi, Kevin C. Grega, Ronda D. Schaadt, W. F. Demyan, Toops Dana S, Gary E. Zurenko, Steven J. Brickner, J. O. Kilburn, Barbachyn Michael R, Debra A. Ulanowicz, Ford Charles W, S. E. Glickman, Judith C. Hamel, J. M. Buysse, Douglas Stapert

المصدر: ChemInform. 27

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Substitution (logic), Identification (biology), General Medicine, Tropone, Antibacterial activity, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::15d27743efd29b12fa0ee68e52d3e0a8
https://doi.org/10.1002/chin.199636129

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ChemInform Abstract: Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

المؤلفون: Susan K. Hendges, Kevin C. Grega, Hutchinson Douglas K, Gary E. Zurenko, Manninen Peter Rudolph, Toops Dana S, Stuart A. Garmon, Ford Charles W, Steven J. Brickner, Debra A. Ulanowicz, Barbachyn Michael R

المصدر: ChemInform. 27

مصطلحات موضوعية: biology, Chemistry, medicine.drug_class, Antibiotics, General Medicine, biology.organism_classification, Microbiology, Multiple drug resistance, Mycobacterium tuberculosis, Antibiotic resistance, Mechanism of action, In vivo, medicine, Vancomycin, medicine.symptom, Antibacterial activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::41e79c504ba9874c79e0b97f0dab22ce
https://doi.org/10.1002/chin.199621139

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