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المؤلفون: Totah RA, Sheffels P, Roberts T, Whittington D, Thummel K, Kharasch ED

المصدر: Anesthesiology; Mar2008, Vol. 108 Issue 3, p363-374, 12p

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المؤلفون: Bercu JP; Gilead Sciences, Inc., Nonclinical Safety and Pathobiology (NSP), Foster City, California, USA., Ponting DJ; Lhasa Limited, Leeds, UK., Ripp SL; Pharmacokinetics, Dynamics & Metabolism, Pfizer Research & Development, Groton, Connecticut, USA., Dobo KL; Drug Safety Research and Development, Pfizer Research & Development, Groton, Connecticut, USA., Totah RA; Department of Medicinal Chemistry, University of Washington, Seattle, Washington, USA., Bolleddula J; Quantitative Pharmacology, EMD Serono Research & Development Institute, Inc., Billerica, Massachusetts, USA.

المصدر: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2024 Jul; Vol. 116 (1), pp. 34-37. Date of Electronic Publication: 2024 Mar 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Rifampin*/therapeutic use , Drug Interactions*, Humans ; Antibiotics, Antitubercular/therapeutic use ; Antibiotics, Antitubercular/adverse effects ; Antibiotics, Antitubercular/pharmacokinetics

المؤلفون: Robey RW; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Fitzsimmons CM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Guiblet WM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Frye WJE; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., González Dalmasy JM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Wang L; Laboratory of Receptor Biology and Gene Expression, Developmental Genomics Group, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Russell DA; Department of Medicinal Chemistry, University of Washington, Seattle, Washington., Huff LM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Perciaccante AJ; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Ali-Rahmani F; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Lipsey CC; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Wade HM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Mitchell AV; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Maligireddy SS; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Terrero D; Department of Pharmacology and Experimental Therapeutics, Department of Cancer Cell and Cancer Biology, University of Toledo, Toledo, Ohio., Butcher D; Molecular Histopathology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Edmondson EF; Molecular Histopathology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Jenkins LM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Nikitina T; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Zhurkin VB; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Tiwari AK; Department of Pharmacology and Experimental Therapeutics, Department of Cancer Cell and Cancer Biology, University of Toledo, Toledo, Ohio., Piscopio AD; OnKure, Inc., Boulder, Colorado., Totah RA; Department of Medicinal Chemistry, University of Washington, Seattle, Washington., Bates SE; Division of Hematology/Oncology, Department of Medicine, Columbia University Medical Center, New York, New York.; Hematology/Oncology Research Department, James J. Peters Department of Veterans Affairs Medical Center, New York, New York., Arda HE; Laboratory of Receptor Biology and Gene Expression, Developmental Genomics Group, Center for Cancer Research, NCI, NIH, Bethesda, Maryland., Gottesman MM; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Batista PJ; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Apr 02; Vol. 23 (4), pp. 464-477.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase Inhibitors*/pharmacology , Histone Deacetylase Inhibitors*/therapeutic use , Neoplasms*/drug therapy, Humans ; Methyltransferases/metabolism ; Panobinostat/pharmacology ; Panobinostat/therapeutic use ; Zinc

المؤلفون: Wiley AM; Department of Medicinal Chemistry, University of WA School of Pharmacy, Seattle, WA, USA., Yang J; Department of Medicinal Chemistry, University of WA School of Pharmacy, Seattle, WA, USA., Madhani R; Department of Medicinal Chemistry, University of WA School of Pharmacy, Seattle, WA, USA., Nath A; Department of Medicinal Chemistry, University of WA School of Pharmacy, Seattle, WA, USA., Totah RA; Department of Medicinal Chemistry, University of WA School of Pharmacy, Seattle, WA, USA.

المصدر: Drug metabolism reviews [Drug Metab Rev] 2024 Feb-May; Vol. 56 (2), pp. 145-163. Date of Electronic Publication: 2024 Mar 20.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0322067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-9883 (Electronic) Linking ISSN: 03602532 NLM ISO Abbreviation: Drug Metab Rev Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP2J2* , Cytochrome P-450 Enzyme System*/metabolism , Long QT Syndrome*/chemically induced , Long QT Syndrome*/metabolism , Cytochrome P-450 Enzyme Inhibitors*/pharmacology, Humans ; Animals

المؤلفون: Czuba LC; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Malhotra K; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Enthoven L; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Fay EE; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Moreni SL; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Mao J; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Shi Y; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Huang W; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Totah RA; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Isoherranen N; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Hebert MF; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington mhebert@uw.edu.

المصدر: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2023 Nov; Vol. 51 (11), pp. 1474-1482. Date of Electronic Publication: 2023 Aug 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP2D6*/metabolism , Dextromethorphan*/metabolism, Humans ; Female ; Pregnancy ; Dextrorphan ; Taurocholic Acid ; Postpartum Period