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المؤلفون: Martin W. Berchtold, Lasse G. Lorentzen, Isabel Porth, Martin R. Larsen, Katarzyna Kulej, Jonas M. la Cour, Triantafyllos Zacharias, S. B. Panina, Mads Munk
المصدر: Berchtold, M W, Munk, M, Kulej, K, Porth, I, Lorentzen, L, Panina, S, Zacharias, T, Larsen, M R & la Cour, J M 2021, ' The heart arrhythmia-linked D130G calmodulin mutation causes premature inhibitory autophosphorylation of CaMKII ', Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1868, no. 12, 119119 . https://doi.org/10.1016/j.bbamcr.2021.119119
مصطلحات موضوعية: Calmodulin, Mutant, Mutation, Missense, Heart failure, Cardiomyocyte, medicine.disease_cause, Mice, Cell Line, Tumor, Ca2+/calmodulin-dependent protein kinase, medicine, Animals, Myocytes, Cardiac, Phosphorylation, CRISPR/Cas9, Molecular Biology, Mutation, CaMKII, biology, Chemistry, Kinase, Autophosphorylation, Wild type, Arrhythmias, Cardiac, Cell Biology, Myocardial Contraction, Cell biology, biology.protein, Calcium, Calcium-Calmodulin-Dependent Protein Kinase Type 2
وصف الملف: application/pdf
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المؤلفون: Triantafyllos Zacharias, Michael J. Davies, Konstantina Flouda, Bente Gammelgaard, Thomas A. Jepps, Carl H. Schiesser
المصدر: Biochemical pharmacology. 173
مصطلحات موضوعية: 0301 basic medicine, Male, Thioredoxin Reductase 1, Antioxidant, Hypochlorous acid, medicine.medical_treatment, Myocytes, Smooth Muscle, chemistry.chemical_element, Inflammation, Pharmacology, In Vitro Techniques, Biochemistry, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Glutathione Peroxidase GPX1, Organoselenium Compounds, medicine, Animals, Humans, Aorta, Cells, Cultured, Hexoses, Glutathione Peroxidase, Molecular Structure, Endothelial Cells, Middle Aged, Coronary Vessels, In vitro, Bioavailability, Oxidative Stress, 030104 developmental biology, chemistry, Protective Agents, Vasoconstriction, 030220 oncology & carcinogenesis, medicine.symptom, Intracellular, Selenium
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المؤلفون: Thomas Jespersen, Jau-Nian Chen, Katarzyna Kulej, Raffaela Torggler, Martin R. Larsen, Jonas M. la Cour, Triantafyllos Zacharias, Kevin Wang, Martin W. Berchtold
المصدر: Berchtold, M W, Zacharias, T, Kulej, K, Wang, K, Torggler, R, Jespersen, T, Chen, J-N, Larsen, M R & la Cour, J M 2016, ' The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish ', Journal of Biological Chemistry, vol. 291, no. 52, pp. 26636-26646 . https://doi.org/10.1074/jbc.M116.758680
The Journal of biological chemistry, vol 291, iss 52مصطلحات موضوعية: 0301 basic medicine, calmodulin, Protein Conformation, Mutant, heart failure, Arrhythmias, Cardiovascular, medicine.disease_cause, Medical and Health Sciences, Biochemistry, Tachycardia, Myocytes, Cardiac, Phosphorylation, Zebrafish, Cells, Cultured, Mutation, Cultured, catecholaminergic polymorphic ventricular tachycardia, Kinase, Autophosphorylation, Biological Sciences, Cell biology, Long QT Syndrome, Heart Disease, Cardiac, Biochemistry & Molecular Biology, medicine.medical_specialty, animal structures, Calmodulin, Cells, Biology, 03 medical and health sciences, Internal medicine, medicine, cell signaling, Animals, Humans, Viability assay, Molecular Biology, Cell Proliferation, Myocytes, calcium, Cell growth, Ventricular, DT40, Arrhythmias, Cardiac, Cell Biology, biology.organism_classification, 030104 developmental biology, Endocrinology, Chemical Sciences, biology.protein, Tachycardia, Ventricular, Calcium, Ca2+/calmodulin-dependent protein kinase II, Calcium-Calmodulin-Dependent Protein Kinase Type 2
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450c2b0ac980a35a6b31621121d1a37
https://pubmed.ncbi.nlm.nih.gov/27815504 -
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المؤلفون: Triantafyllos Zacharias, Ioanna-Katerina Aggeli, Georgia Papapavlou, Isidoros Beis, Catherine Gaitanaki
المصدر: Canadian Journal of Physiology and Pharmacology. 91:1095-1106
مصطلحات موضوعية: medicine.medical_specialty, Programmed cell death, Physiology, chemistry.chemical_element, Apoptosis, Calcium, p38 Mitogen-Activated Protein Kinases, Bcl-2-associated X protein, Physiology (medical), Internal medicine, medicine, Animals, Fragmentation (cell biology), Rana ridibunda, bcl-2-Associated X Protein, Pharmacology, Calcium metabolism, TUNEL assay, Cell Death, L-Lactate Dehydrogenase, biology, Calpain, Myocardium, Heart, General Medicine, Endocrinology, chemistry, biology.protein, Poly(ADP-ribose) Polymerases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90991c5df85d46f0e7739acc2f2801ba
https://doi.org/10.1139/cjpp-2013-0081
