نتائج البحث - "Trypanosoma brucei brucei/genetics"

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كتاب

المساهمون: Barry, David (J David)

مصطلحات موضوعية: Trypanosoma., Trypanosoma -- genetics., Trypanosoma brucei brucei -- genetics., Leishmania major -- genetics., Trypanosoma cruzi -- genetics.

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Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation

المؤلفون: Leal, Andrea Zurita, Schwebs, Marie, Briggs, Emma, Weisert, Nadine, Reis, Helena, Lemgruber, Leandro, Luko, Katarina, Wilkes, Jonathan, Butter, Falk, McCulloch, Richard, Janzen, Christian J

المصدر: Leal, A Z, Schwebs, M, Briggs, E, Weisert, N, Reis, H, Lemgruber, L, Luko, K, Wilkes, J, Butter, F, McCulloch, R & Janzen, C J 2020, ' Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation ', Nucleic Acids Research, vol. 48, no. 17, pp. 9660-9680 . https://doi.org/10.1093/nar/gkaa686
Nucleic Acids Research

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2bc879cdb11e5fa85d6adad39ce9d5ab
https://hdl.handle.net/20.500.11820/d1b64ac1-6db2-4e94-9a94-1939e105a396

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رسالة جامعية

Genome characterisation and mobility investigation in trypanosomes

المؤلفون: Branche, Carole

مصطلحات موضوعية: Trypanosoma -- genetics, Trypanosoma -- physiology, Genome, protozoan, Trypanosoma cruzi -- genetics, Trypanosoma cruzi -- physiology, Trypanosoma brucei brucei -- genetics, Trypanosoma brucei brucei -- physiology, Flagella -- genetics, Chagas disease -- parasitology

URL الوصول: http://diss.kib.ki.se/2006/91-7140-682-4/

Degree: Diss. (sammanfattning) Stockholm : Karol. inst., 2006

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Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids

المؤلفون: Inês Loureiro, Nuno Santarém, Joana Tavares, Joana Faria, Sandra Macedo-Ribeiro, Pedro Cecílio, Anabela Cordeiro-da-Silva

المساهمون: Instituto de Investigação e Inovação em Saúde

المصدر: Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: 0301 basic medicine, Leishmaniasis, Visceral/parasitology, Trypanosoma brucei brucei/enzymology, Mutant, Protozoan Proteins, Gene Expression, Isomerase, medicine.disease_cause, Mice, Ribulosephosphates, Antiprotozoal Agents/pharmacology, Trypanosoma brucei brucei/drug effects, Leishmania infantum/enzymology, Leishmania infantum, Aldose-Ketose Isomerases, Leishmania infantum/genetics, Mutation, Multidisciplinary, Genes, Essential, Pyrrolidinones, 3. Good health, Complementation, Aldose-Ketose Isomerases/genetics, Ribose-5-phosphate isomerase, Trypanosoma brucei brucei/genetics, Biochemistry, Liver, Ribosemonophosphates/metabolism, Life Cycle Stages/genetics, Protozoan Proteins/genetics, Leishmaniasis, Visceral, Ribosemonophosphates, Trypanosomiasis, African/parasitology, Plasmids, Protozoan Proteins/metabolism, Isomerase activity, Pyrrolidinones/pharmacology, Trypanosoma brucei brucei, Antiprotozoal Agents, Plasmids/chemistry, Biology, Trypanosoma brucei, Article, 03 medical and health sciences, Leishmania infantum/growth & development, Liver/parasitology, Aldose-Ketose Isomerases/metabolism, medicine, Animals, Humans, Amino Acid Sequence, Gene, Life Cycle Stages/drug effects, Life Cycle Stages, 030102 biochemistry & molecular biology, Sequence Homology, Amino Acid, Genetic Complementation Test, Leishmania infantum/drug effects, Plasmids/metabolism, biology.organism_classification, Molecular biology, Disease Models, Animal, 030104 developmental biology, Trypanosomiasis, African, Ribulosephosphates/metabolism, Sequence Alignment, Gene Deletion

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb73ed76e56ff21852cd4d0324b1d30

Find this article in full text from ProQuest

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Antitumor Quinol PMX464 Is a Cytocidal Anti-trypanosomal Inhibitor Targeting Trypanothione Metabolism*

المؤلفون: Susan Wyllie, Paul G. Wyatt, Alan H. Fairlamb, Malcolm F. G. Stevens, Geoffrey Wells, Janine König

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Amide Synthases/metabolism, Time Factors, Spermidine, Thioredoxin reductase, Trypanothione, Protozoan Proteins, Amide Synthases/genetics, Biochemistry, chemistry.chemical_compound, Thioredoxins, Cysteine/metabolism, Trypanosomiasis/drug therapy, Trypanosoma brucei brucei/metabolism, Thioredoxins/genetics, biology, Glutathione/genetics, Drug Action, Thioredoxins/metabolism, Glutathione, Trypanocidal Agents, Trypanosoma brucei brucei/genetics, Tryparedoxin Peroxidase, Thiol, Drug, medicine.symptom, Thioredoxin, Antineoplastic Agents/pharmacology, Peroxidase, Protozoan Proteins/metabolism, Trypanosomiasis/genetics, Cysteine/genetics, Glutathione/analogs & derivatives, Trypanosoma brucei brucei, Trypanosomiasis/metabolism, Antineoplastic Agents, Trypanosoma brucei, Trypanosome, Dose-Response Relationship, Amide Synthases, Trypanosomiasis, medicine, Spermidine/analogs & derivatives, Animals, Benzothiazoles/pharmacology, Benzothiazoles, Cysteine, Molecular Biology, Hydroquinones/pharmacology, Dose-Response Relationship, Drug, Cell Biology, biology.organism_classification, Glutathione/metabolism, Spermidine/metabolism, Hydroquinones, Metabolism, Mechanism of action, chemistry, biology.protein, Peroxiredoxin, Trypanocidal Agents/pharmacology, Quinol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644701f01b2fea36b4b7629a41fa03c3
http://europepmc.org/articles/PMC3048735

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Ribose 5-Phosphate Isomerase B Knockdown Compromises Trypanosoma brucei Bloodstream Form Infectivity

المؤلفون: Sandra Macedo-Ribeiro, Christine Clayton, Nilanjan Roy, Anabela Cordeiro-da-Siva, Nuno Santarém, Joana Faria, Inês Loureiro, Joana Tavares

المساهمون: Instituto de Investigação e Inovação em Saúde

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 9, Iss 1, p e3430 (2015)

مصطلحات موضوعية: Glucose-6-phosphate isomerase, Isomerase activity, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, Trypanosoma brucei brucei/enzymology, Trypanosoma brucei brucei, Antibodies, Protozoan, Isomerase, Trypanosoma brucei, Pentose phosphate pathway, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, chemistry.chemical_compound, Mice, Ribose, parasitic diseases, Aldose-Ketose Isomerases/metabolism, Animals, Cloning, Molecular, Trypanosoma brucei brucei/metabolism, Trypanosoma cruzi, Molecular Biology, Aldose-Ketose Isomerases, 030304 developmental biology, 0303 health sciences, biology, 030306 microbiology, lcsh:Public aspects of medicine, Public Health, Environmental and Occupational Health, Biology and Life Sciences, lcsh:RA1-1270, biology.organism_classification, 3. Good health, Aldose-Ketose Isomerases/genetics, Infectious Diseases, Ribose-5-phosphate isomerase, Trypanosomiasis, African, chemistry, Biochemistry, Trypanosoma brucei brucei/genetics, Gene Knockdown Techniques, Parasitology, RNA Interference, Trypanosomiasis, African/parasitology, Trypanosomiasis, African/blood, Research Article

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af85b00ee781bfac34009576d245503
https://repositorio-aberto.up.pt/handle/10216/118188

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Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation

المؤلفون: Christopher Proudfoot, Richard McCulloch

المصدر: Nucleic Acids Research
Proudfoot, C & McCulloch, R 2005, ' Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation ', Nucleic Acids Research, vol. 33, no. 21, pp. 6906-19 .

مصطلحات موضوعية: Rec A Recombinases/physiology, DNA Repair, Trypanosoma brucei brucei/enzymology, DNA repair, Genes, Protozoan, Molecular Sequence Data, Trypanosoma brucei brucei, RAD51, Protozoan Proteins, Protozoan Proteins/analysis, Trypanosoma brucei, medicine.disease_cause, Article, Cell Line, 03 medical and health sciences, parasitic diseases, Genetics, medicine, Antigenic variation, Animals, Cell Nucleus/enzymology, Amino Acid Sequence, Gene, 030304 developmental biology, Cell Nucleus, Recombination, Genetic, 0303 health sciences, Mutation, Rec A Recombinases/genetics, biology, 030302 biochemistry & molecular biology, DNA Repair Pathway, biology.organism_classification, Antigenic Variation, Rec A Recombinases, Trypanosoma brucei brucei/genetics, Protozoan Proteins/physiology, Protozoan Proteins/genetics, Rec A Recombinases/analysis, Homologous recombination, Sequence Alignment, DNA Damage