نتائج البحث - "Trypsin -- metabolism"

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A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa

المؤلفون: Anders B. Sorensen, Per Greisen, Jesper J. Madsen, Jacob Lund, Gorm Andersen, Pernille G. Wulff-Larsen, Anette A. Pedersen, Prafull S. Gandhi, Michael T. Overgaard, Henrik Østergaard, Ole H. Olsen

المصدر: Sorensen, A B, Greisen, P J, Madsen, J J, Lund, J, Andersen, G, Wulff-Larsen, P G, Pedersen, A A, Gandhi, P S, Overgaard, M T, Østergaard, H & Olsen, O H 2022, ' A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa ', Scientific Reports, vol. 12, no. 1, 3747 . https://doi.org/10.1038/s41598-022-07620-7

مصطلحات موضوعية: Serine Endopeptidases/metabolism, Multidisciplinary, Serine Endopeptidases, Trypsin, Factor VIIa, Trypsin/metabolism, Substrate Specificity

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76db24a5a1ef10c061682678804cfa1
https://vbn.aau.dk/ws/files/482458848/s41598_022_07620_7.pdf

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رسالة جامعية

Kallikrein-related peptidases in human epidermis : studies on activity, regulation, and function

المؤلفون: Stefansson, Kristina

مصطلحات موضوعية: Epidermis -- enzymology, Kallikreins -- metabolism, Kallikreins -- physiology, Serine endopeptidases -- metabolism, Trypsin -- metabolism, Receptor, PAR-2 -- physiology

URL الوصول: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1644

Degree: Diss. (sammanfattning) Umeå : Univ., 2008

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دورية أكاديمية

Identification of aphid salivary proteins: a proteomic investigation of Myzus persicae.

المؤلفون: Harmel, Nicolas, Letocart, E., Cherqui, A., Giordanengo, P., Mazzucchelli, Gabriel, Guillonneau, F., De Pauw, Edwin, Haubruge, Eric, Francis, Frédéric

المصدر: Insect Molecular Biology, 17 (2), 165-74 (2008)

مصطلحات موضوعية: Amylases/metabolism, Animals, Aphids/enzymology/metabolism, Electrophoresis, Polyacrylamide Gel, Glucose 1-Dehydrogenase/metabolism, Glucose Oxidase/metabolism, Insect Proteins/chemistry/metabolism, NADH Dehydrogenase/metabolism, Proteomics/methods, Salivary Proteins and Peptides/chemistry/metabolism, Spectrometry, Mass, Electrospray Ionization, Tandem Mass Spectrometry, Trypsin/metabolism, alpha-Glucosidases/metabolism, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:0962-1075; urn:issn:1365-2583

URL الوصول: https://orbi.uliege.be/handle/2268/34208

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Modelling ligand selectivity of serine proteases using integrative proteochemometric approaches improves model performance and allows the multi-target dependent interpretation of features

المؤلفون: Andreas Bender, Oscar Méndez-Lucio, Qurrat ul Ain, Thérèse E. Malliavin, Isidro Cortes Ciriano, Gerard J. P. van Westen

المساهمون: Bender, Andreas [0000-0002-6683-7546], Apollo - University of Cambridge Repository, The Unilever Centre for Molecular Science Informatics - Department of Chemistry [Cambridge, UK], University of Cambridge [UK] (CAM), Bioinformatique structurale - Structural Bioinformatics, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), European Bioinformatics Institute [Hinxton] (EMBL-EBI), EMBL Heidelberg, The authors thank Chad H. G. Allen and Lewis Mervin for proof reading the manuscript. Q.U.A. thanks the Islamic Develop- ment Bank and Cambridge Commonwealth Trust for Funding. O.M.L. is grateful to CONACyT (No. 217442/312933) and the Cambridge Overseas Trust for funding. G.v.W thanks EMBL (EIPOD) and Marie Curie (COFUND) for funding. A.B. thanks Unilever and the ERC (Starting Grant ERC-2013-StG 336159 MIXTURE) for funding. ICC thanks the Institut Pasteur and the Pasteur-Paris International PhD programme for funding. TM thanks the Institut Pasteur for funding., European Project: 336159,EC:FP7:ERC,ERC-2013-StG,MIXTURE(2014), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Integrative Biology, 6(11), 1023-1033
Integrative biology
Integrative biology, Royal Society of Chemistry, 2014, 6 (11), pp.1023-1033. ⟨10.1039/C4IB00175C⟩
Integrative biology, 2014, 6 (11), pp.1023-1033. ⟨10.1039/C4IB00175C⟩

مصطلحات موضوعية: MESH: Serine Proteinase Inhibitors/pharmacology, Proteases, Quantitative structure–activity relationship, Serine Proteinase Inhibitors, medicine.medical_treatment, Biophysics, MESH: Amino Acid Sequence, MESH: Thrombin/antagonists & inhibitors, 01 natural sciences, Biochemistry, Serine, 03 medical and health sciences, medicine, Trypsin, Amino Acid Sequence, Binding site, MESH: Models, Theoretical, 030304 developmental biology, MESH: Serine Proteases/metabolism, Serine protease, 0303 health sciences, MESH: Blood Coagulation Factors/antagonists & inhibitors, Binding Sites, Protease, biology, Thrombin, Active site, Models, Theoretical, Ligand (biochemistry), [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Blood Coagulation Factors, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, MESH: Binding Sites, biology.protein, MESH: Trypsin/metabolism, Serine Proteases