المؤلفون: Tsuchida CA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, CA 94720.; Innovative Genomics Institute, University of California, Berkeley, CA 94720., Wasko KM; Innovative Genomics Institute, University of California, Berkeley, CA 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720., Hamilton JR; Innovative Genomics Institute, University of California, Berkeley, CA 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720., Doudna JA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, CA 94720.; Innovative Genomics Institute, University of California, Berkeley, CA 94720.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; Department of Chemistry, University of California, Berkeley, CA 94720.; California Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720.; Gladstone Institutes, University of California, San Francisco, CA 94158.; HHMI, University of California, Berkeley, CA 94720.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 12; Vol. 121 (11), pp. e2307796121. Date of Electronic Publication: 2024 Mar 04.

نوع المنشور: Review; Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Commerce* , Gene Editing*, Genetic Therapy ; RNA, Messenger ; Ribonucleoproteins

المؤلفون: Adler BA; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Trinidad MI; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA., Bellieny-Rabelo D; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Zhang E; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA., Karp HM; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Skopintsev P; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Thornton BW; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Weissman RF; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Yoon PH; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Chen L; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, CA 94720, USA., Hessler T; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, CA 94720, USA.; Department of Environmental Science, Policy, and Management, University of California, Berkeley, CA 94720, USA.; EGSB Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA., Eggers AR; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Colognori D; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Boger R; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Doherty EE; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Tsuchida CA; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA., Tran RV; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Hofman L; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Graduate School of Life Sciences, Utrecht University, 3584 CS Utrecht, UT, The Netherlands., Shi H; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA., Wasko KM; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Zhou Z; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Xia C; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA., Al-Shimary MJ; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Patel JR; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Thomas VCJX; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Chemistry, University of California, Berkeley, CA 94720, USA., Pattali R; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Kan MJ; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Pediatrics, Division of Allergy, Immunology, and Bone Marrow Transplantation, University of California, San Francisco, CA 94158, USA., Vardapetyan A; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Yang A; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Lahiri A; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Maxwell MF; Department of Chemistry and Biochemistry, Hampton University, Hampton, VA 23668, USA., Murdock AG; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Ramit GC; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Henderson HR; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA., Calvert RW; Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC 3168, Australia., Bamert RS; Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC 3168, Australia., Knott GJ; Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC 3168, Australia., Lapinaite A; School of Molecular Sciences, Arizona State University, Tempe, AZ 85281, USA.; Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.; Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA., Pausch P; LSC-EMBL Partnership Institute for Genome Editing Technologies, Life Sciences Center, Vilnius University, Vilnius 10257, Lithuania., Cofsky JC; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Sontheimer EJ; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA., Wiedenheft B; Department of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA., Fineran PC; Department of Microbiology and Immunology, University of Otago, Dunedin 9016, New Zealand.; Genetics Otago, University of Otago, Dunedin 9016, New Zealand.; Bioprotection Aotearoa, University of Otago, Dunedin 9016, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Otago, Dunedin 9016, New Zealand., Brouns SJJ; Department of Bionanoscience, Delft University of Technology, 2629 HZ Delft, Netherlands.; Kavli Institute of Nanoscience, 2629 HZ Delft, The Netherlands., Sashital DG; Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA., Thomas BC; Metagenomi, Inc., Emeryville, CA 94608, USA., Brown CT; Metagenomi, Inc., Emeryville, CA 94608, USA., Goltsman DSA; Metagenomi, Inc., Emeryville, CA 94608, USA., Barrangou R; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27606, USA., Siksnys V; Institute of Biotechnology, Life Sciences Center, Vilnius University, Vilnius 10257, Lithuania., Banfield JF; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, CA 94720, USA.; Department of Environmental Science, Policy, and Management, University of California, Berkeley, CA 94720, USA.; EGSB Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; The University of Melbourne, Parkville, VIC 3052, Australia., Savage DF; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA., Doudna JA; Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, CA 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.; Department of Chemistry, University of California, Berkeley, CA 94720, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.; MBIB Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Gladstone Institutes, University of California, San Francisco, CA 94158, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2024 Jan 05; Vol. 52 (D1), pp. D590-D596.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*/genetics , CRISPR-Associated Proteins*/chemistry , CRISPR-Associated Proteins*/classification , CRISPR-Associated Proteins*/genetics , Databases, Genetic* , Endodeoxyribonucleases*/chemistry , Endodeoxyribonucleases*/classification , Endodeoxyribonucleases*/genetics, Phylogeny ; Encyclopedias as Topic

المؤلفون: Tsuchida CA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Brandes N; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Bueno R; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Trinidad M; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Mazumder T; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Yu B; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA; Parker Institute for Cancer Immunotherapy, Stanford University School of Medicine, Stanford, CA, USA., Hwang B; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Chang C; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA., Liu J; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA., Sun Y; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Hopkins CR; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Parker KR; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA., Qi Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Hofman L; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA; Graduate School of Life Sciences, Utrecht University, Utrecht, the Netherlands., Satpathy AT; Parker Institute for Cancer Immunotherapy, Stanford University School of Medicine, Stanford, CA, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Stadtmauer EA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cate JHD; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Eyquem J; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA., Fraietta JA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., June CH; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Chang HY; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA; Parker Institute for Cancer Immunotherapy, Stanford University School of Medicine, Stanford, CA, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA., Ye CJ; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA; Chan Zuckerberg Biohub, San Francisco, CA, USA; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA; Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, CA, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA. Electronic address: jimmie.ye@ucsf.edu., Doudna JA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA; Department of Chemistry, University of California Berkeley, Berkeley, CA, USA; Howard Hughes Medical Institute, University of California Berkeley, Berkeley, CA, USA. Electronic address: doudna@berkeley.edu.

المصدر: Cell [Cell] 2023 Oct 12; Vol. 186 (21), pp. 4567-4582.e20. Date of Electronic Publication: 2023 Oct 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*/genetics , Gene Editing*/methods , T-Lymphocytes* , Chromosome Aberrations*, Humans ; Chromosomes ; DNA Damage ; Clinical Trials as Topic

المؤلفون: Tsuchida CA; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; These authors contributed equally to this work., Brandes N; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; These authors contributed equally to this work., Bueno R; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; These authors contributed equally to this work.; Present address: BioMarin Pharmaceutical Inc., Novato, CA, USA., Trinidad M; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA., Mazumder T; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Yu B; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Parker Institute for Cancer Immunotherapy, Stanford University School of Medicine, Stanford, CA, USA., Hwang B; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Present address: Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, South Korea., Chang C; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA.; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA., Liu J; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA.; Present address: Altos Labs, Redwood City, CA, USA., Sun Y; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Hopkins CR; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Parker KR; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Present address: Cartography Biosciences, South San Francisco, CA, USA., Qi Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Satpathy AT; Parker Institute for Cancer Immunotherapy, Stanford University School of Medicine, Stanford, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Stadtmauer EA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cate JHD; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Eyquem J; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA., Fraietta JA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., June CH; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Chang HY; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Parker Institute for Cancer Immunotherapy, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA., Ye CJ; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.; Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA., Doudna JA; University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 22. Date of Electronic Publication: 2023 Mar 22.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Tsuchida CA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, California 94720, USA; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA., Zhang S; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Doost MS; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, California 94720, USA., Zhao Y; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Wang J; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., O'Brien E; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, California 94720, USA., Fang H; Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China., Li CP; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Li D; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Hai ZY; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China., Chuck J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, Jupiter, Florida 33458, USA., Brötzmann J; Department of Structural Cell Biology, Max Planck Institute of Biochemistry, Martinsried, Germany., Vartoumian A; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, California 94720, USA., Burstein D; School of Molecular Cell Biology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 6997801, Israel., Chen XW; Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China., Nogales E; California Institute for Quantitative Biosciences, University of California, Berkeley, California 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA; Molecular Biophysics & Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA., Doudna JA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, California 94720, USA; Innovative Genomics Institute, University of California, Berkeley, California 94720, USA; California Institute for Quantitative Biosciences, University of California, Berkeley, California 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA; Molecular Biophysics & Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, California 94720, USA; Department of Chemistry, University of California, Berkeley, California 94720, USA; Gladstone Institute of Data Science and Biotechnology. Gladstone Institutes, San Francisco, California 94158, USA. Electronic address: doudna@berkeley.edu., Liu JG; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address: junjiegogoliu@tsinghua.edu.cn.

المصدر: Molecular cell [Mol Cell] 2022 Mar 17; Vol. 82 (6), pp. 1199-1209.e6. Date of Electronic Publication: 2022 Feb 25.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Gene Editing*/methods , RNA, Guide, CRISPR-Cas Systems*/genetics , RNA, Guide, CRISPR-Cas Systems*/metabolism, Animals ; CRISPR-Cas Systems/genetics ; Endonucleases/genetics ; Endonucleases/metabolism ; Mammals/metabolism ; RNA/genetics

المؤلفون: Stahl EC; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Gopez AR; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Tsuchida CA; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Fan VB; University of California, Berkeley, Berkeley, CA, United States of America., Moehle EA; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Witkowsky LB; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Hamilton JR; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Lin-Shiao E; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., McElroy M; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., McDevitt SL; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Ciling A; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Tsui CK; University of California, Berkeley, Berkeley, CA, United States of America., Pestal K; University of California, Berkeley, Berkeley, CA, United States of America., Gildea HK; University of California, Berkeley, Berkeley, CA, United States of America., Keller A; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Sylvain IA; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Williams C; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Hirsh A; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Ehrenberg AJ; University of California, Berkeley, Berkeley, CA, United States of America., Kantor R; University of California, Berkeley, Berkeley, CA, United States of America.; Department of Civil and Environmental Engineering, University of California, Berkeley, CA, United States of America., Metzger M; University of California, Berkeley, Berkeley, CA, United States of America.; Department of Civil and Environmental Engineering, University of California, Berkeley, CA, United States of America., Nelson KL; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America.; Department of Civil and Environmental Engineering, University of California, Berkeley, CA, United States of America., Urnov FD; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Ringeisen BR; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Giannikopoulos P; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Doudna JA; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, CA, United States of America.

مؤلفون مشاركون: IGI Testing Consortium

المصدر: PloS one [PLoS One] 2021 Nov 10; Vol. 16 (11), pp. e0258263. Date of Electronic Publication: 2021 Nov 10 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19/*virology , Ribonuclease P/*genetics , SARS-CoV-2/*genetics , Wastewater/*virology, DNA Primers/genetics ; Humans ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction/methods ; Sensitivity and Specificity ; Specimen Handling/methods ; Wastewater-Based Epidemiological Monitoring

المؤلفون: Hamilton JR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Stahl EC; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Tsuchida CA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America.; San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, United States of America., Lin-Shiao E; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Tsui CK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America., Pestal K; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America., Gildea HK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America., Witkowsky LB; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Moehle EA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., McDevitt SL; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., McElroy M; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Keller A; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Sylvain I; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Hirsh A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Ciling A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Ehrenberg AJ; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America.; Department of Integrative Biology, University of California, Berkeley, Berkeley, CA, United States of America., Ringeisen BR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Huberty G; Washington Hospital Healthcare System Clinical Laboratory, Fremont, CA, United States of America., Urnov FD; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Giannikopoulos P; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Doudna JA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, United States of America.; Gladstone Institutes, San Francisco, CA, United States of America.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, United States of America.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, United States of America.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, United States of America.

مؤلفون مشاركون: IGI SARS-CoV-2 Consortium

المصدر: PloS one [PLoS One] 2021 Aug 05; Vol. 16 (8), pp. e0255690. Date of Electronic Publication: 2021 Aug 05 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Testing/*methods , RNA, Viral/*isolation & purification , SARS-CoV-2/*genetics, Adult ; COVID-19/diagnosis ; Female ; Humans ; Male ; Mass Screening/methods ; RNA/genetics ; RNA/isolation & purification ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction/methods ; Robotics/methods ; Saliva/chemistry ; Specimen Handling/methods

المؤلفون: Pausch P; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; VU LSC-EMBL Partnership for Genome Editing Technologies, Life Sciences Center, Vilnius University, Vilnius, Lithuania., Soczek KM; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA., Herbst DA; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Tsuchida CA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA., Al-Shayeb B; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA, USA., Banfield JF; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA.; Department of Earth and Planetary Sciences, University of California, Berkeley, Berkeley, CA, USA., Nogales E; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Howard Hughes Medical Institute, Baltimore, MD, USA., Doudna JA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA. doudna@berkeley.edu.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA. doudna@berkeley.edu.; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA, USA. doudna@berkeley.edu.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. doudna@berkeley.edu.; Howard Hughes Medical Institute, Baltimore, MD, USA. doudna@berkeley.edu.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA. doudna@berkeley.edu.; Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA. doudna@berkeley.edu.

المصدر: Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Aug; Vol. 28 (8), pp. 652-661. Date of Electronic Publication: 2021 Aug 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: DNA Cleavage* , Molecular Conformation*, CRISPR-Associated Proteins/*metabolism , CRISPR-Cas Systems/*genetics , Clustered Regularly Interspaced Short Palindromic Repeats/*genetics, Bacteriophages/genetics ; DNA/metabolism ; DNA-Binding Proteins/metabolism ; Gene Editing ; Genetic Techniques ; RNA, Guide, CRISPR-Cas Systems/metabolism

المؤلفون: Hamilton JR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA., Tsuchida CA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA., Nguyen DN; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA., Shy BR; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., McGarrigle ER; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA., Sandoval Espinoza CR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA., Carr D; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA., Blaeschke F; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA., Marson A; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA; Parker Institute for Cancer Immunotherapy, San Francisco, CA 94158, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA., Doudna JA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA; University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA; Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA; California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: doudna@berkeley.edu.

المصدر: Cell reports [Cell Rep] 2021 Jun 01; Vol. 35 (9), pp. 109207.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cell Engineering* , Gene Transfer Techniques* , Transgenes*, CRISPR-Cas Systems/*genetics, A549 Cells ; CD4-Positive T-Lymphocytes/metabolism ; CRISPR-Associated Protein 9/metabolism ; Gene Editing ; HIV-1/physiology ; Humans ; Jurkat Cells ; Lentivirus/genetics ; Receptors, Chimeric Antigen/metabolism ; Ribonucleoproteins/metabolism ; Virion/metabolism ; env Gene Products, Human Immunodeficiency Virus

المؤلفون: Ehrenberg AJ; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Moehle EA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Brook CE; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Doudna Cate AH; University of California, Berkeley, California, United States of America., Witkowsky LB; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Sachdeva R; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hirsh A; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Barry K; Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America., Hamilton JR; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Lin-Shiao E; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., McDevitt S; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Valentin-Alvarado L; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Letourneau KN; University of California, Berkeley, California, United States of America., Hunter L; University of California, Berkeley, California, United States of America., Keller A; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Pestal K; University of California, Berkeley, California, United States of America., Frankino PA; University of California, Berkeley, California, United States of America., Murley A; University of California, Berkeley, California, United States of America., Nandakumar D; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Stahl EC; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Tsuchida CA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Gildea HK; University of California, Berkeley, California, United States of America., Murdock AG; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hochstrasser ML; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., O'Brien E; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Ciling A; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Tsitsiklis A; University of California, Berkeley, California, United States of America., Worden K; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Dugast-Darzacq C; University of California, Berkeley, California, United States of America., Hays SG; University of California, Berkeley, California, United States of America., Barber CC; University of California, Berkeley, California, United States of America., McGarrigle R; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Lam EK; University of California, Berkeley, California, United States of America., Ensminger DC; University of California, Berkeley, California, United States of America., Bardet L; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Sherry C; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Harte A; University of California, Berkeley, California, United States of America.; University Health Services, University of California, Berkeley, California, United States of America., Nicolette G; University of California, Berkeley, California, United States of America.; University Health Services, University of California, Berkeley, California, United States of America., Giannikopoulos P; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hockemeyer D; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America.; Chan Zuckerberg Biohub, San Francisco, California, United States of America., Petersen M; University of California, Berkeley, California, United States of America., Urnov FD; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Ringeisen BR; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Boots M; University of California, Berkeley, California, United States of America., Doudna JA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, California, United States of America.

مؤلفون مشاركون: IGI SARS-CoV-2 Testing Consortium

المصدر: PloS one [PLoS One] 2021 May 26; Vol. 16 (5), pp. e0251296. Date of Electronic Publication: 2021 May 26 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Program Evaluation*, COVID-19/*diagnosis , Saliva/*virology, Adult ; Aged ; COVID-19/epidemiology ; COVID-19/virology ; COVID-19 Testing/methods ; Female ; Humans ; Male ; Middle Aged ; RNA, Viral/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Social Norms ; Surveys and Questionnaires ; Universities ; Young Adult