المؤلفون: İş Ö; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Wang X; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Reddy JS; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Min Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Yilmaz E; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Bhattarai P; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Patel T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Bergman J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Quicksall Z; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Heckman MG; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Tutor-New FQ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Can Demirdogen B; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Biomedical Engineering, TOBB University of Economics and Technology, Ankara, Turkey., White L; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Koga S; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Krause V; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Inoue Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Kanekiyo T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Cosacak MI; German Center for Neurodegenerative Diseases (DZNE) within Helmholtz Association, Dresden, Germany., Nelson N; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA., Lee AJ; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Vardarajan B; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Mayeux R; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Kouri N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Deniz K; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Carnwath T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Oatman SR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lewis-Tuffin LJ; Mayo Clinic Florida Cytometry and Cell Imaging Laboratory, Mayo Clinic, Jacksonville, FL, USA., Nguyen T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Graff-Radford J; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Alzheimer's Disease Research Center, Rochester, MN, USA., Jr Jack CR; Mayo Clinic, Radiology, Rochester, MN, USA., Kantarci K; Mayo Clinic Alzheimer's Disease Research Center, Rochester, MN, USA., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Nho K; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, USA., Saykin AJ; Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.; Indiana Alzheimer's Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Kizil C; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.; The Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA., Allen M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. taner.nilufer@mayo.edu.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA. taner.nilufer@mayo.edu.

مؤلفون مشاركون: Alzheimer’s Disease Neuroimaging Initiative

المصدر: Nature communications [Nat Commun] 2024 Jun 20; Vol. 15 (1), pp. 4758. Date of Electronic Publication: 2024 Jun 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/genetics , Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/pathology , Smad3 Protein*/metabolism , Smad3 Protein*/genetics , Zebrafish* , Astrocytes*/metabolism , Vascular Endothelial Growth Factor A*/metabolism , Vascular Endothelial Growth Factor A*/genetics , Pericytes*/metabolism , Pericytes*/pathology, Humans ; Animals ; Male ; Induced Pluripotent Stem Cells/metabolism ; Female ; Aged ; Transcriptome ; Brain/metabolism ; Brain/pathology ; Brain/blood supply ; Aged, 80 and over ; Disease Models, Animal

المؤلفون: Min Y; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Center for Clinical and Translational Science, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Jacksonville, FL, USA., Wang X; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., İş Ö; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Patel TA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Gao J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Reddy JS; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Quicksall ZS; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Nguyen T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lin S; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Tutor-New FQ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Chalk JL; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Mitchell AO; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Crook JE; Center for Clinical and Translational Science, Mayo Clinic, Rochester, MN, USA., Nelson PT; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.; Department of Pathology & Laboratory Medicine, University of Kentucky, Lexington, KY, USA., Van Eldik LJ; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.; Department of Neuroscience, University of Kentucky, Lexington, KY, USA., Golde TE; Department of Pharmacology and Chemical Biology, Department of Neurology, Emory Center for Neurodegenerative Disease, Emory University, Atlanta, GA, USA., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Zhang K; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Allen M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. taner.nilufer@mayo.edu.; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA. taner.nilufer@mayo.edu.

المصدر: Nature communications [Nat Commun] 2023 Nov 02; Vol. 14 (1), pp. 6801. Date of Electronic Publication: 2023 Nov 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Supranuclear Palsy, Progressive*/pathology , Tauopathies*/pathology , Discoidin Domain Receptor 2*, Humans ; Animals ; Mice ; tau Proteins/metabolism ; Systems Biology ; Neuroglia/metabolism

المؤلفون: Patel T; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Carnwath TP; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Wang X; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, USA., Allen M; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Lincoln SJ; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Lewis-Tuffin LJ; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida, USA., Quicksall ZS; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, USA., Lin S; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Tutor-New FQ; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Ho CCG; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Min Y; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Malphrus KG; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Nguyen TT; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Martin E; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA., Garcia CA; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA., Alkharboosh RM; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience Graduate Program, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, Minnesota, USA.; Regenerative Sciences Training Program, Center for Regenerative Medicine, Mayo Clinic, Rochester, Minnesota, USA., Grewal S; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA., Chaichana K; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA., Wharen R; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA., Guerrero-Cazares H; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA., Quinones-Hinojosa A; Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA.

المصدر: Aging cell [Aging Cell] 2022 May; Vol. 21 (5), pp. e13606. Date of Electronic Publication: 2022 Apr 06.

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/metabolism , Neurodegenerative Diseases*/genetics , Neurodegenerative Diseases*/metabolism, Apolipoproteins E/genetics ; Apolipoproteins E/metabolism ; Humans ; Microglia/metabolism ; Transcriptome/genetics

المؤلفون: Wang X; Department of Quantitative Health Sciences and., Allen M; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., İş Ö; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Reddy JS; Department of Quantitative Health Sciences and., Tutor-New FQ; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Castanedes Casey M; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Carrasquillo MM; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Oatman SR; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Min Y; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Asmann YW; Department of Quantitative Health Sciences and., Funk C; Institute for Systems Biology, Seattle, Washington, USA., Nguyen T; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Ho CC; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Malphrus KG; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Seyfried NT; Department of Biochemistry and., Levey AI; Department of Neurology, Emory University, Atlanta, Georgia, USA., Younkin SG; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Murray ME; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Dickson DW; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA., Price ND; Institute for Systems Biology, Seattle, Washington, USA., Golde TE; Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA., Ertekin-Taner N; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.; Department of Neurology, Mayo Clinic Florida, Jacksonville, Florida, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2022 Jan 18; Vol. 132 (2).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*, Alzheimer Disease/*metabolism , Brain/*metabolism , Supranuclear Palsy, Progressive/*metabolism, Aged ; Female ; Humans ; Male