المؤلفون: Danny T. Huang, Helge M. Magnussen

المصدر: Journal of Molecular Biology

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Xenopus, Regulator, Gene Expression, medicine.disease_cause, Crystallography, X-Ray, RMSD, Root-mean-square deviation, 0302 clinical medicine, E3, Structural Biology, GST, Glutathione S-transferase, Catalytic Domain, Conserved Sequence, Zebrafish, Mammals, 0303 health sciences, Mutation, biology, Chemistry, Proto-Oncogene Proteins c-mdm2, Small molecule, Recombinant Proteins, Ubiquitin ligase, MDM2h, human MDM2 419-C, Domain (ring theory), TEV, Tobacco Etch Virus, Protein Binding, Research Article, SPR, Surface plasmon resonance, E2(UbcH5B)~Ub, thioester bond-linked E2~Ub conjugate, Protein design, E2(UbcH5B)–Ub, isopeptide-linked E2–Ub conjugate, Computational biology, Ring (chemistry), 03 medical and health sciences, Protein Aggregates, Aggregation, Protein Domains, MDM2, medicine, Animals, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Molecular Biology, neoplasms, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, Sequence Homology, Amino Acid, Ubiquitin, Mutagenesis, Ubiquitination, MDM2z, Danio rerio MDM2 407-C, Ubiquitin-Conjugating Enzymes, biology.protein, Biocatalysis, Protein Conformation, beta-Strand, MDM2f, Xenopus tropicalis MDM2 414-C, Tumor Suppressor Protein p53, Protein Processing, Post-Translational, Sequence Alignment, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1d09f643ebb18e3d1991e060fd5fc3
https://pubmed.ncbi.nlm.nih.gov/33450248

المؤلفون: Amrita Patel, Gary J. Sibbet, Danny T. Huang

المصدر: Journal of Biological Chemistry
The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, ubiquitin-conjugating enzyme (E2 enzyme), Stereochemistry, Protein Conformation, Protein degradation, Ring (chemistry), Crystallography, X-Ray, Biochemistry, ubiquitin ligase, Inhibitor of Apoptosis Proteins, Turn (biochemistry), 03 medical and health sciences, Ubiquitin, structural biology, Humans, ubiquitylation (ubiquitination), RING E3, Molecular Biology, UbcH5B, chemistry.chemical_classification, DNA ligase, 030102 biochemistry & molecular biology, biology, Chemistry, apoptosis, Ubiquitination, Cell Biology, non-covalent, allosteric regulation, Ubiquitin ligase, cIAP1, 030104 developmental biology, Structural biology, E3 ubiquitin ligase, Covalent bond, Protein Synthesis and Degradation, Ubiquitin-Conjugating Enzymes, biology.protein, protein degradation, activation, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0ed8fbc72a4ec2f42fb5cf9ce61444

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