المؤلفون: Taylor JD; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK. jonathan.taylor@astrazeneca.com., Barrett N; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Martinez Cuesta S; Data Sciences and Quantitative Biology, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge, CB2 0AA, UK., Cassidy K; Protein Sciences, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca, Waltham, MA, 02451, USA., Pachl F; Protein Sciences, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca, Waltham, MA, 02451, USA., Dodgson J; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Patel R; Centre for Genomics Research, Dynamic Omics, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge, CB2 0AA, UK., Eriksson TM; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Riley A; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Burrell M; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Bauer C; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Rees DG; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Cimbro R; Centre for Genomics Research, Dynamic Omics, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge, CB2 0AA, UK., Zhang AX; Protein Sciences, Discovery Sciences, R&D BioPharmaceuticals, AstraZeneca, Waltham, MA, 02451, USA., Minter RR; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK., Hunt J; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK. james.hunt1@astrazeneca.com., Legg S; Biologics Engineering, R&D Oncology, AstraZeneca, Cambridge, CB2 0AA, UK.

المصدر: Communications biology [Commun Biol] 2024 Sep 19; Vol. 7 (1), pp. 1179. Date of Electronic Publication: 2024 Sep 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , Proteolysis* , Protein Tyrosine Phosphatase, Non-Receptor Type 11*/metabolism , Protein Tyrosine Phosphatase, Non-Receptor Type 11*/genetics, Humans ; Ubiquitination ; Proto-Oncogene Proteins p21(ras)/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Recombinant Fusion Proteins/metabolism ; Recombinant Fusion Proteins/genetics ; HEK293 Cells ; Proteomics/methods ; Protein Binding

المؤلفون: Deng Y; Department of Medical Oncology, The First Affiliated Hospital of Fujian Medical University, , Fuzhou, Fujian Province, 350005, China.; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Chen X; Department of Thoracic Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian Province, 350014, China., Chen X; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Huang C; Laboratory of Immuno-Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, 420 Fuma Rd. Jin'an District, Fuzhou, Fujian Province, 350014, China., Zhang Z; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Xu Z; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Wang X; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Wu J; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Li L; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Song J; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China., Zhou R; Key Laboratory of Gastrointestinal Cancer, Ministry of Education, Fujian Medical University, Fuzhou, Fujian Province, 350108, China. rxzhou@fjmu.edu.cn.; School of Basic Medical Sciences, Fujian Medical University, No. 1 Xueyuan Road, Fuzhou, Fujian, 350108, China. rxzhou@fjmu.edu.cn.

المصدر: BMC cancer [BMC Cancer] 2024 Sep 18; Vol. 24 (1), pp. 1158. Date of Electronic Publication: 2024 Sep 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitination* , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/metabolism , Lung Neoplasms*/genetics , Adenocarcinoma of Lung*/pathology , Adenocarcinoma of Lung*/metabolism , Adenocarcinoma of Lung*/genetics , Disease Progression* , Cell Proliferation* , Pre-B-Cell Leukemia Transcription Factor 1*/metabolism , Pre-B-Cell Leukemia Transcription Factor 1*/genetics , Epithelial-Mesenchymal Transition*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Female ; Cell Movement ; Neoplasm Staging ; Male ; Gene Expression Regulation, Neoplastic ; Middle Aged ; Mice, Nude ; Nuclear Receptor Subfamily 1, Group F, Member 1

المؤلفون: Wang B; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu 210000, China; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China., Li F; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu 210000, China., Hu J; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu 210000, China; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China., Sun F; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu 210000, China; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China., Han L; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu 210000, China; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China., Zhang J; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu 210000, China; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China. Electronic address: 101011288@seu.edu.cn., Zhu B; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, Jiangsu 210000, China; Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China. Electronic address: zhubl@jscdc.cn.

المصدر: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Sep 15; Vol. 283, pp. 116773. Date of Electronic Publication: 2024 Jul 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis*/drug effects , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , Benzene*/toxicity , Autophagy*/drug effects, Humans ; Environmental Pollutants/toxicity ; Prospective Studies ; Male ; Adult ; Female

المؤلفون: Kochańczyk T; Structural Biology Program, Sloan Kettering Institute, New York, NY, USA.; Howard Hughes Medical Institute, New York, NY, USA., Hann ZS; Structural Biology Program, Sloan Kettering Institute, New York, NY, USA.; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lux MC; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Chemical Biology Program, Sloan Kettering Institute, New York, NY, USA., Delos Reyes AMV; Chemical Biology Program, Sloan Kettering Institute, New York, NY, USA.; Pharmacology Graduate Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ji C; Chemical Biology Program, Sloan Kettering Institute, New York, NY, USA., Tan DS; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. tand@mskcc.org.; Chemical Biology Program, Sloan Kettering Institute, New York, NY, USA. tand@mskcc.org.; Pharmacology Graduate Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA. tand@mskcc.org., Lima CD; Structural Biology Program, Sloan Kettering Institute, New York, NY, USA. limac@mskcc.org.; Howard Hughes Medical Institute, New York, NY, USA. limac@mskcc.org.; Tri-Institutional PhD Program in Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. limac@mskcc.org.

المصدر: Nature [Nature] 2024 Sep; Vol. 633 (8028), pp. 216-223. Date of Electronic Publication: 2024 Aug 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Protein Processing, Post-Translational* , Schizosaccharomyces pombe Proteins*/chemistry , Schizosaccharomyces pombe Proteins*/metabolism , Schizosaccharomyces pombe Proteins*/ultrastructure , Sulfhydryl Compounds*/chemistry , Sulfhydryl Compounds*/metabolism , Ubiquitin*/chemistry , Ubiquitin*/metabolism , Ubiquitin*/ultrastructure , Ubiquitin-Activating Enzymes*/chemistry , Ubiquitin-Activating Enzymes*/metabolism , Ubiquitin-Activating Enzymes*/ultrastructure , Ubiquitin-Conjugating Enzymes*/chemistry , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/ultrastructure , Ubiquitin-Protein Ligases*/chemistry , Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/ultrastructure, Cryoelectron Microscopy ; Esterification ; Models, Molecular ; Protein Conformation ; Schizosaccharomyces/enzymology ; Schizosaccharomyces/ultrastructure

المؤلفون: Jiang Y; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, China., Liu B; Cardiovascular Disease Center, The First Hospital of Jilin University, Jilin University, Changchun, China., Fu L; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, China., Li F; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, China; The Key Laboratory for Bionics Engineering, Ministry of Education, Jilin University, Changchun, China; Key Laboratory for Health Biomedical Materials of Jilin Province, Jilin University, Changchun, China; Engineering Research Center for Medical Biomaterials of Jilin Province, Jilin University, Changchun, China; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang, China. Electronic address: lifan@jlu.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Sep; Vol. 276 (Pt 2), pp. 134011. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/genetics , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , NF-E2-Related Factor 2*/metabolism , NF-E2-Related Factor 2*/genetics , Autophagy*/genetics , Kelch-Like ECH-Associated Protein 1*/metabolism , Kelch-Like ECH-Associated Protein 1*/genetics , Signal Transduction* , Cell Proliferation* , Gene Expression Regulation, Neoplastic*, Humans ; Cell Line, Tumor ; Cell Movement/genetics ; Ubiquitination

المؤلفون: Lv P; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.; Institute of Andrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China., Liu J; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. jhliu@tjh.tjmu.edu.cn.; Institute of Andrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. jhliu@tjh.tjmu.edu.cn., Liu X; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. xmliu77@hust.edu.cn.; Institute of Andrology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. xmliu77@hust.edu.cn.

المصدر: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2024 Aug 28; Vol. 22 (1), pp. 110. Date of Electronic Publication: 2024 Aug 28.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101153627 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7827 (Electronic) Linking ISSN: 14777827 NLM ISO Abbreviation: Reprod Biol Endocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Spermatogenesis*/physiology , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/physiology, Male ; Humans ; Animals ; Ubiquitination/physiology ; Meiosis/physiology

المؤلفون: Cybulla E; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA., Wallace S; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Meroni A; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Jackson J; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Agashe S; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Tennakoon M; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Limbu M; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Quinet A; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Lomonosova E; Department of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO 63110, USA., Noia H; Department of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO 63110, USA., Tirman S; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Wood M; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA., Lemacon D; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA., Fuh K; Division of Gynecologic Oncology, Department of Ob/Gyn and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143, USA., Zou L; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27708, USA., Vindigni A; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2024 Aug 27; Vol. 52 (15), pp. 8861-8879.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , DNA Replication* , BRCA1 Protein*/metabolism , BRCA1 Protein*/genetics , BRCA1 Protein*/deficiency , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , Fanconi Anemia Complementation Group N Protein*/genetics , Fanconi Anemia Complementation Group N Protein*/metabolism, Humans ; Cell Line, Tumor ; Ubiquitination ; Proliferating Cell Nuclear Antigen/metabolism ; Proliferating Cell Nuclear Antigen/genetics ; DNA Repair

المؤلفون: van de Kooij B; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands. l.w.van.de.kooij@umcg.nl.; Koch Institute for Integrative Cancer Research, MIT Center for Precision Cancer Medicine, Departments of Biology and Bioengineering, Massachusetts Institute of Technology, Cambridge, MA, USA. l.w.van.de.kooij@umcg.nl.; Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. l.w.van.de.kooij@umcg.nl., van der Wal FJ; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Rother MB; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Wiegant WW; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Creixell P; Koch Institute for Integrative Cancer Research, MIT Center for Precision Cancer Medicine, Departments of Biology and Bioengineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; CRUK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom., Stout M; Department of Molecular Mechanisms of Disease, University of Zurich (UZH), Zurich, Switzerland., Joughin BA; Koch Institute for Integrative Cancer Research, MIT Center for Precision Cancer Medicine, Departments of Biology and Bioengineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Vornberger J; Department of Molecular Mechanisms of Disease, University of Zurich (UZH), Zurich, Switzerland., Altmeyer M; Department of Molecular Mechanisms of Disease, University of Zurich (UZH), Zurich, Switzerland., van Vugt MATM; Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Yaffe MB; Koch Institute for Integrative Cancer Research, MIT Center for Precision Cancer Medicine, Departments of Biology and Bioengineering, Massachusetts Institute of Technology, Cambridge, MA, USA. myaffe@mit.edu.; Department of Surgery, Beth Israel Deaconess Medical Center, Divisions of Acute Care Surgery, Trauma, and Critical Care and Surgical Oncology, Harvard Medical School, Boston, USA. myaffe@mit.edu., van Attikum H; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands. h.van.attikum@lumc.nl.

المصدر: Nature communications [Nat Commun] 2024 Aug 16; Vol. 15 (1), pp. 7076. Date of Electronic Publication: 2024 Aug 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: DNA Breaks, Double-Stranded* , Fanconi Anemia Complementation Group D2 Protein*/metabolism , Fanconi Anemia Complementation Group D2 Protein*/genetics , Fanconi Anemia Complementation Group L Protein*/metabolism , Fanconi Anemia Complementation Group L Protein*/genetics , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , Homologous Recombination*, Humans ; Nuclear Proteins/metabolism ; Nuclear Proteins/genetics ; Carrier Proteins/metabolism ; Carrier Proteins/genetics ; CRISPR-Cas Systems ; Ubiquitination ; Fanconi Anemia/genetics ; Fanconi Anemia/metabolism ; Endodeoxyribonucleases/metabolism ; Endodeoxyribonucleases/genetics ; HEK293 Cells ; Recombinational DNA Repair ; DNA Repair ; DNA End-Joining Repair ; DNA Helicases

المؤلفون: Lin X; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China.; Graduate School of Medicine, Hebei North University, Zhangjiakou, Hebei, China., Sun D; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Yang S; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Cheng K; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Wang X; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Meng W; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Wu H; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Liu W; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Wu X; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China., Yang H; Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China., Wang X; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China. wjfpost@tom.com., Zhou L; Taizhou Central Hospital (Taizhou University Hospital), School of Medicine, Taizhou University, Taizhou, Zhejiang, China. lishazhou@tzc.edu.cn.

المصدر: Cell death & disease [Cell Death Dis] 2024 Aug 13; Vol. 15 (8), pp. 590. Date of Electronic Publication: 2024 Aug 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , Breast Neoplasms*/metabolism , Breast Neoplasms*/pathology , Breast Neoplasms*/genetics , Breast Neoplasms*/drug therapy , Drug Resistance, Neoplasm*/drug effects , Estrogen Receptor alpha*/metabolism , Feedback, Physiological*, Humans ; Female ; Animals ; Disease Progression ; Mice, Nude ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Mice ; Apoptosis/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Fulvestrant/pharmacology ; Ubiquitination ; MCF-7 Cells

المؤلفون: Kaminskaya AN; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Evpak AS; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Belogurov AA Jr; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Department of Biological Chemistry, Russian University of Medicine, Ministry of Health of Russian Federation, 127473 Moscow, Russia., Kudriaeva AA; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 08; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Ubiquitin*/metabolism , Ubiquitination* , Evolution, Molecular* , Signal Transduction* , Ubiquitin-Conjugating Enzymes*/metabolism , Ubiquitin-Conjugating Enzymes*/genetics , Ubiquitin-Conjugating Enzymes*/chemistry, Humans ; Animals ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/chemistry ; Protein Processing, Post-Translational ; Phylogeny