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1دورية أكاديمية
المؤلفون: Rienk Offringa, Catherine Olesch, Frederik Cichon, Mareike Grees, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Michael Erkelenz, Thi Thanh Uyen Nguyen, Ulf Boemer, Judith Günther, Marc Kunze, Kirstin Petersen, Dennis Kirchhoff
المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2051-1426
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المؤلفون: Steven M. Corsello, Huajia Zhang, Rajesha Rupaimoole, Volker K. Schulze, Clara Lemos, Kasia B. Handing, Douglas L. Orsi, Mrinal Shekhar, Ulrike Sack, Sven Christian, Wilhelm Bone, Ranad Humeidi, William Colgan, Stephanie Hoyt, Andrew Cherniack, Jens Schroder, Stefan Kaulfuss, Krzysztof Brzezinka, Oliver von Ahsen, Anne Mengel, Roman C. Hillig, Detlev Suelzle, Jeremie Mortier, Caitlin Harrington, Rohith Nagari, Justyna Wierzbinska, Derek Chiang, Georg Beckmann, Meagan Olive, Namrata Udeshi, Annie Apffel, Steven Carr, Philip Lienau, Christian Lechner, Ulf Boemer, Alisha Caliman, David McKinney, Florence Wagner, Dominik Mumberg, Marcus Bauser, Andrea Haegebarth, Knut Eis, Ashley Eheim, Todd R. Golub
المصدر: Cancer Research. 82:3588-3588
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eda27f4110e552a48e195fe20ca593a7
https://doi.org/10.1158/1538-7445.am2022-3588 -
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المؤلفون: Holger Hess-Stumpp, Marie-Pierre Collin, Stuart Ince, Oliver Politz, Uwe Thuss, Sebastian Bender, Klemens Lustig, Dieter Zopf, Christoph Kneip, Peter Ellinghaus, Dominik Mumberg, Sylvia Grünewald, Ulf Boemer, Charlotte Kopitz, Mélanie Héroult, Karl Ziegelbauer
المصدر: International Journal of Cancer
مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Lung Neoplasms, Colorectal cancer, Cell, Mice, Nude, colorectal cancer, Antineoplastic Agents, Breast Neoplasms, Thiophenes, Fibroblast growth factor, Piperazines, Mice, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Human Umbilical Vein Endothelial Cells, cancer, Animals, Humans, Medicine, Pyrroles, Phosphorylation, Kinase activity, Cancer Therapy and Prevention, Mice, Inbred BALB C, rogaratinib, Bladder cancer, business.industry, Cancer, medicine.disease, preclinical models, Receptors, Fibroblast Growth Factor, Xenograft Model Antitumor Assays, Rats, medicine.anatomical_structure, Oncology, Fibroblast growth factor receptor, 030220 oncology & carcinogenesis, fibroblast growth factor receptor, Cancer research, Female, Drug Screening Assays, Antitumor, Colorectal Neoplasms, business
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المؤلفون: Hans Briem, Benjamin Bader, Ulf Boemer, Brice Sautier, N. Bohnke, A. Hilpmann, Nicolas Werbeck, J. Kahmann, Volker Badock, D. Wegener, Knut Eis, J. Schroeder, K. Graham, Dieter Moosmayer, Christian Stegmann, J. Mastouri, K. Petersen, Jörg Weiske, Gerhard Siemeister, Roman C. Hillig, Lars Wortmann, F. von Nussbaum
المصدر: 'Proceedings of the National Academy of Sciences of the USA ', vol: 116, pages: 2551-2560 (2019)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 116(7), 2551-2560 (2019). doi:10.1073/pnas.1812963116مصطلحات موضوعية: crystal structure, GTP', Crystallography, X-Ray, medicine.disease_cause, Biochemistry, Cell Line, Proto-Oncogene Proteins p21(ras), Drug Discovery, Fluorescence Resonance Energy Transfer, medicine, Humans, Small GTPase, Mode of action, Multidisciplinary, Chemistry, Drug discovery, fragment screen, SOS, Biological Sciences, High-Throughput Screening Assays, Cell biology, PNAS Plus, SOS1, ddc:500, Guanine nucleotide exchange factor, KRAS, Signal transduction, SOS1 Protein, small-molecule inhibitor, Protein Binding, Signal Transduction, RAS
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b81d68c52d5b8e57b984ebab279c8e8
https://doi.org/10.1073/pnas.1812963116 -
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المؤلفون: Timothy A. Lewis, Franziska Siegel, Ulf Boemer, Bethany Kaplan, Heidi Greulich, Franz von Nussbaum, Jens Schroeder, Stephan Siegel, K. Petersen, Ursula Moenning, Mario Hermsen, Florian Prinz, Matthew Meyerson, Sabine Zitzmann-Kolbe, Andrew D. Cherniack, Daniel Korr, Detlev Suelzle, Uwe Eberspaecher, Knut Eis, Keith Graham, Gizem Karsli-Uzunbas
المصدر: Cancer Research. 81:1470-1470
مصطلحات موضوعية: Cancer Research, Mutation, business.industry, medicine.medical_treatment, Mutant, Cancer, medicine.disease, medicine.disease_cause, Targeted therapy, Exon, T790M, Oncology, Cancer cell, Cancer research, Medicine, Osimertinib, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6267af0034fe42b36e3b59f0f149a452
https://doi.org/10.1158/1538-7445.am2021-1470 -
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المؤلفون: Uwe Eberspaecher, Rienk Offringa, Gabriele Leder, Judith Guenther, Roland Neuhaus, Bertolt Kreft, Rafael Carretero, Jeffrey Mowat, Ingo Hartung, Ulf Boemer, Martina Schaefer, Nicolas Werbeck, Mine Oezcan-Wahlbrink, Nuria Aiguabella Font, Sandra Berndt, Barbara Nicke, Corinna Link, Oliver von Ahsen, Mareike Grees, Daniel Baumann
المصدر: Cancer Research. 81:1722-1722
مصطلحات موضوعية: Cancer Research, Tumor microenvironment, biology, Chemistry, Kinase, Cell, Immune checkpoint, medicine.anatomical_structure, Oncology, Immunity, biology.protein, medicine, Cancer research, Antibody, Protein kinase A, Intracellular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8c95b8a195d1c33ac1081db66cf562fd
https://doi.org/10.1158/1538-7445.am2021-1722 -
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المؤلفون: Franziska Siegel, Carl Friedrich Nising, Franz von Nussbaum, Ulf Boemer, Herbert Himmel, Detlev Suelzle, Marcus Bauser, Uwe Eberspaecher, Simon Holton, Joerg Weiske, Florian Prinz, Ralf Lesche, Clara Lemos, Dominik Mumberg, Dieter Moosmayer, Knut Eis, Andrea Haegebarth, Stefan Prechtl, Barbara Nicke, Duy Nguyen, Lars Wortmann, Christian Lechner, Katrin Nowak-Reppel
المصدر: Journal of medicinal chemistry. 62(2)
مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Pyridines, Cell, Drug Evaluation, Preclinical, Apoptosis, Crystallography, X-Ray, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Protein structure, RNA interference, Drug Discovery, medicine, Structure–activity relationship, Humans, Binding site, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase 7, Cell Proliferation, Binding Sites, Kinase, Chemistry, Cell Differentiation, Small molecule, Cell biology, Protein Structure, Tertiary, Molecular Docking Simulation, 030104 developmental biology, medicine.anatomical_structure, Pyrimidines, Cell culture, 030220 oncology & carcinogenesis, Molecular Medicine, Half-Life, Signal Transduction
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المؤلفون: Maria Castedo, Ulf Boemer, Dominik Mumberg, Antje Margret Wengner, Mohamed Jemaà, Ariane Abrieu, Laura Senovilla, Ilio Vitale, Stefan Prechtl, Guido Kroemer, Volker Schulze, Karl Ziegelbauer, Lorenzo Galluzzi, Oliver Kepp, Philip Lienau, Gerhard Siemeister, Marcus Koppitz, Michael Brands
المصدر: Cell Death & Differentiation. 20:1532-1545
مصطلحات موضوعية: Paclitaxel, Mice, Nude, Apoptosis, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Biology, Transfection, Mice, Random Allocation, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Animals, Humans, Protein Kinase Inhibitors, Molecular Biology, Mitotic catastrophe, Mitosis, Metaphase, Anaphase, Original Paper, Cell Cycle, Drug Synergism, Cell Biology, Protein-Tyrosine Kinases, Cell cycle, Xenograft Model Antitumor Assays, Spindle apparatus, Cell biology, Spindle checkpoint, Cancer cell, Female, HeLa Cells
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المؤلفون: Matthias Friebe, Jan Andersson, Miklós Tóth, Andrea Varrone, Damian Brockschnieder, Ludger Dinkelborg, Balázs Gulyás, Tobias Heinrich, Heribert Schmitt-Willich, Christer Halldin, Sabine Krause, Thomas Dyrks, Ulf Boemer
المصدر: Journal of Nuclear Medicine. 53:1794-1801
مصطلحات موضوعية: Male, Fluorine Radioisotopes, Pathology, medicine.medical_specialty, Biodistribution, Amyloid, Pyridines, Standardized uptake value, Pharmacology, Mice, In vivo, medicine, Amyloid precursor protein, Animals, Humans, Radiology, Nuclear Medicine and imaging, Radioactive Tracers, Amyloid beta-Peptides, biology, Chemistry, medicine.disease, Macaca mulatta, In vitro, Frontal Lobe, Positron-Emission Tomography, biology.protein, Female, Alzheimer's disease, Ex vivo, Half-Life
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المؤلفون: Franz von Nussbaum, Ulf Boemer, Michael Brands, Wolf-Dietrich Doecke, Nicole Schmidt, Reinhard Nubbemeyer, Holger Steuber, Eleni Lagkadinou, Oliver Politz, Ulrich Bothe, Andreas Steinmeyer, Holger Siebeneicher, Judith Guenther, Antje Margret Wengner, Dominik Mumberg, Lisette Potze, Thomas M. Zollner, Martin Lange, Karl Ziegelbauer
المصدر: Cancer Research. 78:1887-1887
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, biology, Chemistry, IRAK4, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Oncology, hemic and lymphatic diseases, 030220 oncology & carcinogenesis, Ibrutinib, biology.protein, Cancer research, Bruton's tyrosine kinase, Signal transduction, Protein kinase B, Tyrosine kinase, PI3K/AKT/mTOR pathway, Copanlisib
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ed9906a0dd171187036a294f5e6b5afc
https://doi.org/10.1158/1538-7445.am2018-1887