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المؤلفون: Mark A. Ashwell, Jean-Marc Lapierre, Christopher Brassard, Karen Bresciano, Cathy Bull, Susan Cornell-Kennon, Sudharshan Eathiraj, Dennis S. France, Terence Hall, Jason Hill, Eoin Kelleher, Sampada Khanapurkar, Darin Kizer, Steffi Koerner, Jeff Link, Yanbin Liu, Sapna Makhija, Magdi Moussa, Nivedita Namdev, Khanh Nguyen, Robert Nicewonger, Rocio Palma, Jeff Szwaya, Manish Tandon, Uma Uppalapati, David Vensel, Laurie P. Volak, Erika Volckova, Neil Westlund, Hui Wu, Rui-Yang Yang, Thomas C. K. Chan
المصدر: Journal of Medicinal Chemistry. 55:5291-5310
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Pyridines, Administration, Oral, Biological Availability, AKT1, Antineoplastic Agents, Plasma protein binding, Pharmacology, Crystallography, X-Ray, Mice, Structure-Activity Relationship, Adenosine Triphosphate, In vivo, Catalytic Domain, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, Phosphorylation, Protein kinase B, Adaptor Proteins, Signal Transducing, Cell Proliferation, Effector, Chemistry, Imidazoles, Ribosomal Protein S6 Kinases, 70-kDa, Small molecule, Biochemistry, Microsomes, Liver, Molecular Medicine, Proto-Oncogene Proteins c-akt, Protein Binding
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المؤلفون: Uma Uppalapati, Mark A. Ashwell, Bin Zhang, Xiubin Gu, David Leggett, Chiang J. Li
المصدر: SLAS Discovery. 13:538-543
مصطلحات موضوعية: Programmed cell death, Indoles, DNA damage, Cell, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Biology, environment and public health, Biochemistry, Analytical Chemistry, Cell Line, Tumor, medicine, Humans, Phosphorylation, RNA, Small Interfering, Coloring Agents, Cytotoxicity, Checkpoint Kinase 2, Fluorescent Dyes, Cell Death, G2-M DNA damage checkpoint, Molecular biology, enzymes and coenzymes (carbohydrates), medicine.anatomical_structure, Fluorescent Antibody Technique, Direct, Cell culture, Enzyme Induction, High-content screening, Trans-Activators, Molecular Medicine, Biological Assay, biological phenomena, cell phenomena, and immunity, DNA Damage, HeLa Cells, Propidium, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16819613f79653412d7fcccae44b09c
https://doi.org/10.1177/1087057108318509 -
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المؤلفون: Thomas C.K. Chan, Mark A. Ashwell, Jean-Marc Lapierre, Christopher Brassard, Cathy Bull, Susan Cornell-Kennon, Sudharshan Eathiraj, Dennis S. France, Jason Hill, Steffi Koerner, Eoin Kelleher, Darin Kizer, Yanbin Liu, Jeff Link, Sapna Makhija, Magdi Moussa, Nivedita Namdev, Robert Nicewonger, Uma Uppalapati, Rocio Palma, Jeff Szwaya, Manish Tandon, David Vensel, Laurie Volak, Erika Volckova, Neil Westland, Hui Wu, Rui-Yang Yang
المصدر: Cancer Research. 72:LB-1
مصطلحات موضوعية: Cancer Research, Effector, Chemistry, AKT1, Cancer, Pharmacology, medicine.disease, Small molecule, In vitro, Oncology, In vivo, medicine, Protein kinase B, Intracellular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::34014a12fe34271da22ab4f26b260726
https://doi.org/10.1158/1538-7445.am2012-lb-1
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