المؤلفون: Maja Zakošek Pipan, Sonja Prpar Mihevc, Malan Štrbenc, Urban Košak, Ilija German Ilić, Jurij Trontelj, Simon Žakelj, Stanislav Gobec, Darja Pavlin, Gregor Majdič

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/32c976e38cff4eb89133a4590bc3ef91

المؤلفون: Urban Košak, Stanislav Gobec

المصدر: Acta Chimica Slovenica, Vol 67, Iss 3, Pp 940-948 (2020)

مصطلحات موضوعية: ((phenylcarbamoyl)oxy)benzoic acids, phenyl isocyanates, carbamates, building blocks, alzheimer’s disease., Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://journals.matheo.si/index.php/ACSi/article/view/6006; https://doaj.org/toc/1318-0207; https://doaj.org/toc/1580-3155

URL الوصول: https://doaj.org/article/1b683dea22254bcf9a4e2596748928b1

المؤلفون: Stane Pajk, Damijan Knez, Urban Košak, Maja Zorović, Xavier Brazzolotto, Nicolas Coquelle, Florian Nachon, Jacques-Philippe Colletier, Marko Živin, Jure Stojan, Stanislav Gobec

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 498-505 (2020)

مصطلحات موضوعية: butyrylcholinesterase, inhibitor, probe, fluorescence, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/dbf12d5fe8ba43da9d6b77ed1a105af9

المؤلفون: Mihajlo Gajic, Damijan Knez, Izidor Sosič, Janez Mravljak, Anže Meden, Urban Košak, Luisa Leitzbach, Sven George, Bettina Hofmann, Aleksandra Zivkovic, Dieter Steinhilber, Holger Stark, Stanislav Gobec, Andrija Smelcerovic, Marko Anderluh

المصدر: ChemMedChem, str. 1-11, Vol. 17, iss. 5, 2022
COBISS-ID: 519053337

مصطلحات موضوعية: Pharmacology, Organic Chemistry, butyrylcholinesterase (BChE), cathepsin B, inhibition of deoxyribonuclease I, Farmacevtska kemija, Ligands, Oxyquinoline, Biochemistry, Cathepsin B, Molecular Docking Simulation, Structure-Activity Relationship, Butyrylcholinesterase, Drug Discovery, Acetylcholinesterase, Molecular Medicine, Deoxyribonuclease I, Cholinesterase Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, udc:615.4

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf3a358ca06ba59bd1a7afc8192721b
https://pubmed.ncbi.nlm.nih.gov/34994078

المؤلفون: Oscar Moreno, Abraham Martín, Pilar Castellnou, Unai Cossío, Albert Giralt, Jordi Llop, Pedro Ramos-Cabrer, Ander Egimendia, Rossana Passannante, Ana Joya, Xabier Ríos-Anglada, Estibaliz Capetillo-Zarate, Stanislav Gobec, Magdalena Sastre, Urban Košak, Damijan Knez, Vanessa Gómez-Vallejo, Luka Rejc, Zuriñe Baz, Mariel Marder, Ignacio Tobalina-Larrea

المصدر: Theranostics
Addi. Archivo Digital para la Docencia y la Investigación
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Dipòsit Digital de la UB
Universidad de Barcelona

مصطلحات موضوعية: 0301 basic medicine, Fluorine Radioisotopes, positron emission tomography, Medicine (miscellaneous), Plaque, Amyloid, Mice, 0302 clinical medicine, Positron Emission Tomography Computed Tomography, Stilbenes, alzheimer disease, Medicine, Tissue Distribution, Carbon Radioisotopes, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Butyrylcholinesterase, Aniline Compounds, biology, Molecular Structure, Biochemical markers, Animal models in research, Alzheimer's disease, medicine.anatomical_structure, Marcadors bioquímics, butyrylcholinesterase, Disease Progression, Female, Amyloid Beta, Research Paper, medicine.medical_specialty, Biodistribution, Amyloid beta, Mice, Transgenic, Nerve Tissue Proteins, Neuroimaging, Blood–brain barrier, 03 medical and health sciences, In vivo, Internal medicine, Animals, 1112 Oncology and Carcinogenesis, Florbetaben, Amyloid beta-Peptides, business.industry, medicine.disease, Mice, Inbred C57BL, amyloid beta, Disease Models, Animal, 030104 developmental biology, Endocrinology, Malaltia d'Alzheimer, PET, biology.protein, Cholinesterase Inhibitors, Models animals en la investigació, Radiopharmaceuticals, business, 030217 neurology & neurosurgery, Ex vivo, Biomarkers

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78aa3f6c23115abd785a53a122b059cb
http://hdl.handle.net/10810/51929

المؤلفون: Philipp Spatz, Takahiro Higuchi, Urban Košak, Damijan Knez, Naoko Nose, Stanislav Gobec, Michael Decker, Xinyu Chen, Christian Gentzsch

مصطلحات موضوعية: Cancer Research, Biodistribution, Chromatography, biology, Chemistry, Radiosynthesis, Binding potential, 030218 nuclear medicine & medical imaging, Dissociation constant, 03 medical and health sciences, 0302 clinical medicine, Oncology, In vivo, Enzyme inhibitor, biology.protein, Radiology, Nuclear Medicine and imaging, ddc:610, IC50, 030217 neurology & neurosurgery, Butyrylcholinesterase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d7bd2b15e59a7a1bd36a74951179c5
https://opus.bibliothek.uni-wuerzburg.de/files/26987/Gentzsch_Molecular.pdf

المؤلفون: Sonja Prpar Mihevc, Darja Pavlin, Malan Štrbenc, Urban Košak, Ilija Ilić, Jurij Trontelj, Gregor Majdic, Maja Zakošek Pipan, Simon Žakelj, Stanislav Gobec

المصدر: Scientific reports, vol. 11, no. 18098, 2021.
Scientific reports, str. [1-10] : Ilustr., art. 18098, Vol. 11, 2021
COBISS-ID: 18727432
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports

مصطلحات موضوعية: dogs, Disease, Severity of Illness Index, Quality of life, canine dementia scale, Informed consent, Medicine, Dog Diseases, Cognitive impairment, udc:636.7.09:616.892, Butyrylcholinesterase, Multidisciplinary, Neurodegenerative diseases, canine cognitive dysfunction, Disease Management, Cognition, Alzheimer's disease, udc:616, Dogs, Cognitive test, Treatment Outcome, Neurology, butyrylcholinesterase, Disease Susceptibility, Alzheimer’s disease, medicine.medical_specialty, Science, Untreated group, Drug development, Article, Quality of life (healthcare), Internal medicine, Dementia, Animals, Cognitive Dysfunction, Cognitive skill, Neurodegeneration, Psychiatry, business.industry, Conflict of interest, medicine.disease, Cholinesterase Inhibitors, business, butyrylcholinesterase inhibitor

وصف الملف: application/pdf; text/url

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba18d374e1d297444ebf4852a2f1e96
https://doi.org/10.21203/rs.3.rs-118291/v1

المؤلفون: Christian, Gentzsch, Xinyu, Chen, Philipp, Spatz, Urban, Košak, Damijan, Knez, Naoko, Nose, Stanislav, Gobec, Takahiro, Higuchi, Michael, Decker

المصدر: Molecular Imaging and Biology

مصطلحات موضوعية: Fluorine Radioisotopes, Positron emission tomography, Radiochemistry, Brain, Enzyme inhibitor, Rats, Biodistribution, Quaternization, Butyrylcholinesterase, Positron-Emission Tomography, Animals, Humans, Radiopharmaceuticals, Alzheimer’s disease, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::88a3da203952b27c71ba637a2ac3d6d6
https://pubmed.ncbi.nlm.nih.gov/33660167

المؤلفون: Xavier Brazzolotto, Florian Nachon, Marko Živin, Jure Stojan, Maja Zorović, Damijan Knez, Jacques-Philippe Colletier, Urban Košak, Stanislav Gobec, Stane Pajk, Nicolas Coquelle

المساهمون: Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Institut Laue-Langevin (ILL), Institut de Recherche Biomédicale des Armées [Antenne Marseille] (IRBA), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Institut de Recherche Biomédicale des Armées (IRBA), ILL, University of Ljubljana, Faculty of Pharmacy, Askerceva 7, 1000 Ljubljana, Slovenia, Faculty of Pharmacy, University of Ljubljana, Département de Toxicologie et Risques Chimiques, Institute of Biochemistry, Faculty of Medicine

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.498-505. ⟨10.1080/14756366.2019.1710502⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2020, 35 (1), pp.498-505. ⟨10.1080/14756366.2019.1710502⟩
Journal of enzyme inhibition and medicinal chemistry, vol. 35, no. 1, pp. 498-505, 2020.
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 498-505 (2020)

مصطلحات موضوعية: Models, Molecular, [SDV]Life Sciences [q-bio], Crystallography, X-Ray, 01 natural sciences, Mice, chemistry.chemical_compound, Drug Discovery, MESH: Animals, Butyrylcholinesterase, chemistry.chemical_classification, zaviralci, Molecular Structure, biology, MESH: Butyrylcholinesterase, General Medicine, MESH: Fluorescent Dyes, Fluorescence, Acetylcholinesterase, MESH: Amides, 3. Good health, inhibitor, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], Fluorescence intensity, Biochemistry, butyrylcholinesterase, fluorescence, patogeneza Alzheimerjeve bolezni, MESH: Cholinesterase Inhibitors, MESH: Models, Molecular, Research Paper, MESH: Molecular Structure, Mixed inhibition, RM1-950, probe, butiriliholinesteraza, Hydrolase, Animals, Humans, [CHIM]Chemical Sciences, udc:616.894+616.892.3:615.2, MESH: Mice, Fluorescent Dyes, Pharmacology, MESH: Humans, 010405 organic chemistry, Active site, MESH: Crystallography, X-Ray, Amides, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, biology.protein, Therapeutics. Pharmacology, Cholinesterase Inhibitors

وصف الملف: application/pdf; text/url

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346bbfead7d353e2e74735bc335c4593
https://hal.science/hal-03014299/file/Pajk2020.pdf

المؤلفون: Nika Strašek, Abida Zahirović, Damijan Knez, Florian Nachon, Urban Košak, Xavier Brazzolotto, Simon Žakelj, Janko Kos, Anja Pišlar, Marko Jukič, Stanislav Gobec

المصدر: European Journal of Medicinal Chemistry. 197:112282

مصطلحات موضوعية: Monoamine Oxidase Inhibitors, Monoamine oxidase, Pharmacology, 01 natural sciences, Neuroprotection, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Piperidines, Alzheimer Disease, Cell Line, Tumor, Drug Discovery, Humans, Enzyme kinetics, Butyrylcholinesterase, 030304 developmental biology, 0303 health sciences, Amyloid beta-Peptides, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, General Medicine, Acetylcholinesterase, Peptide Fragments, 0104 chemical sciences, Neuroprotective Agents, Monoamine neurotransmitter, chemistry, Drug Design, biology.protein, Carbamates, Cholinesterase Inhibitors, Monoamine oxidase B, Protein Multimerization, Monoamine oxidase A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fee10e02a975ea027fb35f6a132662
https://doi.org/10.1016/j.ejmech.2020.112282