المؤلفون: Heppner DE; Department of Chemistry, The State University of New York at Buffalo. Buffalo, New York 14221, United States., Ogboo BC; Department of Chemistry, The State University of New York at Buffalo. Buffalo, New York 14221, United States., Urul DA; AssayQuant Technologies Inc., Marlboro, Massachusetts 01752, United States., May EW; AssayQuant Technologies Inc., Marlboro, Massachusetts 01752, United States., Schaefer EM; AssayQuant Technologies Inc., Marlboro, Massachusetts 01752, United States., Murkin AS; Department of Chemistry, The State University of New York at Buffalo. Buffalo, New York 14221, United States., Gehringer M; Division of Medicinal Chemistry, Institute of Biomedical Engineering, University Hospital Tübingen and Institute of Pharmaceutical Sciences, University of Tübingen. 72076 Tübingen, Germany.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Aug 08. Date of Electronic Publication: 2024 Aug 08.

نوع المنشور: Editorial

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

المؤلفون: Wittlinger F; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Ogboo BC; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA., Shevchenko E; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies' Eberhard Karls Universität Tübingen, 72076, Tübingen, Germany.; Tübingen Center for Academic Drug Discovery & Development (TüCAD2), 72076, Tübingen, Germany., Damghani T; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA., Pham CD; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA., Schaeffner IK; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA., Oligny BT; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA., Chitnis SP; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA., Beyett TS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, 5119 Rollins Research Center, 1510 Clifton Rd, Atlanta, GA, 30322, USA., Rasch A; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Buckley B; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14203, USA., Urul DA; AssayQuant Technologies, Inc., Marlboro, MA, 01752, USA., Shaurova T; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14203, USA., May EW; AssayQuant Technologies, Inc., Marlboro, MA, 01752, USA., Schaefer EM; AssayQuant Technologies, Inc., Marlboro, MA, 01752, USA., Eck MJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA., Hershberger PA; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14203, USA., Poso A; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies' Eberhard Karls Universität Tübingen, 72076, Tübingen, Germany.; Tübingen Center for Academic Drug Discovery & Development (TüCAD2), 72076, Tübingen, Germany.; School of Pharmacy, University of Eastern Finland, 70210, Kuopio, Finland., Laufer SA; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany. stefan.laufer@uni-tuebingen.de.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies' Eberhard Karls Universität Tübingen, 72076, Tübingen, Germany. stefan.laufer@uni-tuebingen.de.; Tübingen Center for Academic Drug Discovery & Development (TüCAD2), 72076, Tübingen, Germany. stefan.laufer@uni-tuebingen.de., Heppner DE; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA. davidhep@buffalo.edu.; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14203, USA. davidhep@buffalo.edu.; Department of Structural Biology, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA. davidhep@buffalo.edu.

المصدر: Communications chemistry [Commun Chem] 2024 Feb 20; Vol. 7 (1), pp. 38. Date of Electronic Publication: 2024 Feb 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Nature Country of Publication: England NLM ID: 101725670 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3669 (Electronic) Linking ISSN: 23993669 NLM ISO Abbreviation: Commun Chem Subsets: PubMed not MEDLINE

المؤلفون: Hoyt KW; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States., Urul DA; AssayQuant Technologies, Inc., Marlboro, Massachusetts 01752, United States., Ogboo BC; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States., Wittlinger F; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., Laufer SA; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls Universität Tübingen, 72076 Tübingen, Germany.; Tübingen Center for Academic Drug Discovery & Development (TüCAD2), 72076 Tübingen, Germany., Schaefer EM; AssayQuant Technologies, Inc., Marlboro, Massachusetts 01752, United States., May EW; AssayQuant Technologies, Inc., Marlboro, Massachusetts 01752, United States., Heppner DE; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States.; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States.; Department of Structural Biology, The State University of New York, Buffalo, New York 14203, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 Jan 11; Vol. 67 (1), pp. 2-16. Date of Electronic Publication: 2023 Dec 22.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: ErbB Receptors* , Enzyme Inhibitors*/pharmacology, Reproducibility of Results ; Drug Design ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/chemistry

المؤلفون: Heppner DE; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States.; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States., Wittlinger F; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., Beyett TS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States., Shaurova T; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States., Urul DA; AssayQuant Technologies, Inc., 260 Cedar Hill St., Marlboro, Massachusetts 01752, United States., Buckley B; Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States., Pham CD; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States., Schaeffner IK; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States., Yang B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States., Ogboo BC; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, United States., May EW; AssayQuant Technologies, Inc., 260 Cedar Hill St., Marlboro, Massachusetts 01752, United States., Schaefer EM; AssayQuant Technologies, Inc., 260 Cedar Hill St., Marlboro, Massachusetts 01752, United States., Eck MJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States., Laufer SA; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls Universität Tübingen, 72076 Tübingen, Germany.; Tübingen Center for Academic Drug Discovery & Development (TüCAD2), 72076 Tübingen, Germany., Hershberger PA; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14203, United States.

المصدر: ACS medicinal chemistry letters [ACS Med Chem Lett] 2022 Nov 10; Vol. 13 (12), pp. 1856-1863. Date of Electronic Publication: 2022 Nov 10 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

المؤلفون: Long MJC; Beverley East Riding of Yorkshire, United Kingdom., Urul DA; Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, United States., Aye Y; Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. Electronic address: yimon.aye@epfl.ch.

المصدر: Methods in enzymology [Methods Enzymol] 2020; Vol. 633, pp. 203-230. Date of Electronic Publication: 2019 Mar 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7988 (Electronic) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

مواضيع طبية MeSH: Antioxidant Response Elements* , Proteins*/genetics , Proteins*/metabolism , Signal Transduction*, Cysteine ; Drug Design ; Oxidation-Reduction

المؤلفون: Van Hall-Beauvais A; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York.; Ecole Polytechnique Fédérale de Lausanne, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland., Zhao Y; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York.; Ecole Polytechnique Fédérale de Lausanne, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland., Urul DA; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York.; Ecole Polytechnique Fédérale de Lausanne, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland., Long MJC; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York., Aye Y; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York.; Department of Biochemistry, Weill Cornell Medicine, New York, New York.; Ecole Polytechnique Fédérale de Lausanne, Institute of Chemical Sciences and Engineering, Lausanne, Switzerland.

المصدر: Current protocols in chemical biology [Curr Protoc Chem Biol] 2018 Sep; Vol. 10 (3), pp. e43. Date of Electronic Publication: 2018 Aug 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101559235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-4762 (Electronic) Linking ISSN: 21604762 NLM ISO Abbreviation: Curr Protoc Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Caenorhabditis elegans/*metabolism , Proteins/*metabolism, Animals ; COS Cells ; Chlorocebus aethiops ; HEK293 Cells ; HeLa Cells ; Humans ; Molecular Structure ; Oxidation-Reduction ; Proteins/chemistry ; Species Specificity

المؤلفون: Surya SL; Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States., Long MJC; Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States., Urul DA; Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States., Zhao Y; Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States., Mercer EJ, EIsaid IM; Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States., Evans T, Aye Y; Department of Chemistry and Chemical Biology , Cornell University , Ithaca , New York 14853 , United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2018 Jul 20; Vol. 13 (7), pp. 1824-1831. Date of Electronic Publication: 2018 Feb 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Aldehydes/*metabolism , HSP27 Heat-Shock Proteins/*metabolism, Aldehydes/chemistry ; Alkylation ; Animals ; Cell Line, Tumor ; Cysteine/chemistry ; HEK293 Cells ; HSP27 Heat-Shock Proteins/chemistry ; HSP27 Heat-Shock Proteins/genetics ; Humans ; Kinetics ; Mutagenesis ; Protein Structure, Secondary ; Sequence Homology, Amino Acid ; Zebrafish

المؤلفون: Long MJC; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States., Urul DA; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States., Chawla S; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States., Lin HY; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States., Zhao Y; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States., Haegele JA; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States., Wang Y; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States., Aye Y; Department of Chemistry and Chemical Biology, Cornell University , Ithaca, New York 14853, United States.; Department of Biochemistry, Weill Cornell Medicine , New York, New York 10065, United States.

المصدر: Biochemistry [Biochemistry] 2018 Jan 16; Vol. 57 (2), pp. 216-220. Date of Electronic Publication: 2017 Sep 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Caenorhabditis elegans/*metabolism , Caenorhabditis elegans Proteins/*analysis, Aldehydes/chemistry ; Animals ; Animals, Genetically Modified ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Caenorhabditis elegans/ultrastructure ; Caenorhabditis elegans Proteins/genetics ; Electrochemistry ; Hydrolases/chemistry ; Hydrolases/genetics ; Kelch-Like ECH-Associated Protein 1/chemistry ; Kelch-Like ECH-Associated Protein 1/genetics ; Longevity ; Luminescent Proteins/analysis ; Luminescent Proteins/chemistry ; Luminescent Proteins/genetics ; Oxidation-Reduction ; Photochemistry ; Protein Processing, Post-Translational ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Transgenes ; Red Fluorescent Protein