المؤلفون: Rafael Balaña-Fouce, Yolanda Pérez-Pertejo, José Miguel Escudero-Martínez, Pablo A. García, Rosa M. Reguera, María Ángeles Castro, Arturo San Feliciano, Pablo G. Jambrina

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 11, Iss, Pp 70-79 (2019)
International Journal for Parasitology: Drugs and Drug Resistance

مصطلحات موضوعية: 0301 basic medicine, LTopIB, Leishmania Type IB DNA Topoisomerase, Topoisomerase Inhibitors, Drug Resistance, Anthraquinones, Mice, 0302 clinical medicine, NQ, Naphthoquinone, Pharmacology (medical), Leishmania infantum, ADME, Mice, Inbred BALB C, biology, Chemistry, Quinones, Regular Article, Acridinequinone, Hep G2 Cells, BAcQ, Benzoacridinequinone, Quinone, DNA-Topoisomerase IB, CPT, Camptothecin, Molecular Docking Simulation, Infectious Diseases, Biochemistry, Leishmaniasis, Visceral, Female, medicine.symptom, Terpenylquinones, Antiparasitic, medicine.drug_class, AQ, Anthraquinone, 030231 tropical medicine, Antiprotozoal Agents, SI, Selectivity Index, VL, Visceral Leishmaniasis, lcsh:Infectious and parasitic diseases, FBS, Foetal Bovine Serum, 03 medical and health sciences, medicine, iRFP, Infrared Fluorescent Protein, Animals, Humans, AMB, Amphotericin B deoxycholate, lcsh:RC109-216, Pharmacology, Macrophages, Druglikeness, biology.organism_classification, In vitro, 030104 developmental biology, Mechanism of action, Docking (molecular), MTF, Miltefosine, Parasitology, Camptothecin, DNA Topoisomerases, Spleen, Naphthoquinones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d9b06ad8097eda5ef9ffab63bf394b
http://www.sciencedirect.com/science/article/pii/S2211320719301095

المؤلفون: Oumaima Nassiri, Boutaina Mouhoub, Noufissa Benajiba, Abdelilah Berhili, Rachid Seddik, Imane El Mezgueldi, Chaymae Rochdi, Mohammed Bensalah, Jalila El Malki, Achraf Miri, Mounia Slaoui, Ali Azghar

المصدر: IDCases
IDCases, Vol 26, Iss, Pp e01247-(2021)

مصطلحات موضوعية: medicine.medical_specialty, MCH, mean corpuscular hemoglobin, Hepatosplenomegaly, MGV, mean globular volume, Case Report, Infectious and parasitic diseases, RC109-216, Sand flies, Neutropenia, Gastroenterology, Pallor, Internal medicine, PT, prothrombin time, medicine, DIC, disseminated intravascular coagulation, Visceral leishmaniasis, medicine.diagnostic_test, LDH, lactate dehydrogenase, business.industry, Complete blood count, medicine.disease, Pancytopenia, MAS, macrophage activation syndrome, Protozoa parasite, Morocco, Infectious Diseases, Macrophage activation syndrome, VL, visceral leishmaniasis, medicine.symptom, Hemophagocytosis, business, HLH, Hemophagocytic Lymphohistiocytosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3d9139b5a020c4d1cb6c8328774035
http://europepmc.org/articles/PMC8371194

المؤلفون: Meixian Xu, Lei Kang, Fang Guo

المصدر: International Journal of Infectious Diseases
International Journal of Infectious Diseases, Vol 97, Iss, Pp 27-29 (2020)

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), endocrine system, Pediatrics, medicine.medical_specialty, bone marrow aspiration, medicine.medical_treatment, HLH, hemophagocytic lymphohistiocytosis, 030106 microbiology, Hepatosplenomegaly, Article, lcsh:Infectious and parasitic diseases, BMA, bone marrow aspiration, VL-HLH, visceral leishmaniasis-related hemophagocytic lymphohistiocytosis, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Amphotericin B, parasitic diseases, medicine, lcsh:RC109-216, 030212 general & internal medicine, Chemotherapy, Hemophagocytic lymphohistiocytosis, biology, business.industry, mNGS, next-generation meta-genome sequencing, fungi, visceral leishmaniasis-related hemophagocytic lymphohistiocytosis, next-generation meta-genome sequencing, General Medicine, musculoskeletal system, medicine.disease, Leishmania, biology.organism_classification, Pancytopenia, Regimen, Infectious Diseases, Visceral leishmaniasis, VL, visceral leishmaniasis, AMB, libosomal amphotericin B, medicine.symptom, business, hormones, hormone substitutes, and hormone antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10440bd84743cdb3d855045483b2cb41
https://doi.org/10.1016/j.ijid.2020.05.056

المؤلفون: Christian Bogdan

المصدر: Cytokine
Cytokine: X, Vol 2, Iss 4, Pp 100041-(2020)

مصطلحات موضوعية: Interferon-α/β, NOS2 (iNOS), type 2 (or inducible) nitric oxide synthase, HO-1, heme oxygenase 1, TGF-β, transforming growth factor-beta, Biochemistry, chemistry.chemical_compound, AHR, aryl hydrocarbon receptor, CR, complement receptor, DC, dendritic cells, Immunology and Allergy, AMP, antimicrobial peptide, Phox, phagocyte NADPH oxidase, Hypoxia, Leishmaniasis, NK cell, natural killer cell, DCL, diffuse cutaneous leishmaniasis, SOCS, suppressor of cytokine signaling, Effector, Hematology, Cell biology, STAT, signal transducer and activator of transcription, NOX2, NADPH oxidase 2 (gp91 or cytochrome b558 β-subunit of Phox), NFAT5, nuclear factor of activated T cells 5, JAK, Janus kinase, Reprogramming, Research Article, lcsh:Immunologic diseases. Allergy, Stromal cell, Immunology, IDO, indoleamine-2,3-dioxygenase, Biology, OXPHOS, mitochondrial oxidative phosphorylation, RNS, reactive nitrogen species, Immune system, ROS, reactive oxygen species, NCX1, Na+/Ca2+ exchanger 1, medicine, CAMP, cathelicidin-type antimicrobial peptide, Tonicity, LPG, lipophosphoglycan, IFN, interferon, TLR, toll-like receptor, Molecular Biology, PKDL, post kala-azar dermal leishmaniasis, NO, nitric oxide, mTOR, mammalian/mechanistic target of rapamycin, Arginase, Macrophages, IFNAR, type I IFN (IFN-α/β) receptor, Nitric oxide, Lipophosphoglycan, medicine.disease, Leishmania, biology.organism_classification, IL, interleukin, Visceral leishmaniasis, Metabolism, chemistry, LRV1, Leishmania RNA virus 1, Phagocyte NADPH oxidase, VL, visceral leishmaniasis, (L)CL, (localized) cutaneous leishmaniasis, Interferon-γ, lcsh:RC581-607, Arg, arginase, Th1 (Th2), type 1 (type2) T helper cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c346b1974962b6f0934f117cb72355
https://pubmed.ncbi.nlm.nih.gov/33604563

المؤلفون: Carolina Santiago, María Ángeles Castro, Arturo San Feliciano, Pablo A. García, María Victoria Rojo, Andrés Abad, Rosa M. Reguera, José Miguel Escudero-Martínez, Rafael Balaña-Fouce, Yolanda Pérez-Pertejo, José Luis López-Pérez

المصدر: International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 7, Iss 3, Pp 272-285 (2017)
GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname

مصطلحات موضوعية: 0301 basic medicine, AMBdc, AMB deoxicholate, AMB, Amphotericin B, parásitos, Microtubules, Mice, Podophyllin, Tubulin, iRFP, Infra Red Fluorescent Protein, Pharmacology (medical), Leishmania infantum, Podophyllotoxin, Leishmania, biology, Podophyllum, NTD, Neglected Tropical Diseases, Hep G2 Cells, Aldehído podofílico, Tubulin Modulators, Infectious Diseases, Biochemistry, Liver, medicine.drug, 030106 microbiology, Instituto de Investigación Biomédica de Salamanca, Tubulina, Article, SI, Selectivity Index, lcsh:Infectious and parasitic diseases, VL, Visceral Leishmaniasis, 03 medical and health sciences, Structure-Activity Relationship, Microtubule, FCS, Foetal Calf Serum, medicine, Animals, Humans, Parasites, lcsh:RC109-216, Podophyllic aldehyde, Ciencias farmacéuticas, Pharmacology, DNA-Topoisomerase, biology.organism_classification, 030104 developmental biology, Docking (molecular), Podofilotoxina, biology.protein, ADN-Topoisomerasa, Parasitology, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799dc84a613335110782f95293a3b480
http://europepmc.org/articles/PMC5512185

المؤلفون: Leopoldo F M, Nascimento, Dayane Francisca Higino, Miranda, Luana D, Moura, Flaviane A, Pinho, Guilherme Loureiro, Werneck, Ricardo, Khouri, Steven G, Reed, Malcolm S, Duthie, Aldina, Barral, Manoel, Barral-Netto, Maria S P, Cruz

المصدر: Vaccine: X

مصطلحات موضوعية: CanL, canine leishmaniosis, Clinical signs, MPL, monophosphoryl lipid A, SLA, Second generation Lipid Adjuvant, SE, stable emulsion, Th1, T helper 1-like cells, IL, interleukin, Parasite, Canine visceral leishmaniasis, Regular paper, GLA, glycopyranosyl lipid, VL, visceral leishmaniasis, IFN, interferon, Drug, Vaccine, TLR, Toll-like receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0ab9f224981577d832b9390e7a90790f
https://pubmed.ncbi.nlm.nih.gov/31891152

المؤلفون: Steven G. Reed, Michelle Favila, Raodoh Mohamath, Hong Liang, John D. Laurance, Kimberly A. Hofmeyer, Steven J. Reed, Rhea N. Coler, Aarthy C. Vallur, Yeung L. Tutterrow, H. Remy Bailor, Malcolm S. Duthie, Julie Vergara, Alessandro Picone, Jeffrey A. Guderian, Randall F. Howard

المصدر: Vaccine

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Antibodies, Protozoan, Immunoglobulin G, Mice, Leishmania, Vaccines, Synthetic, Leishmaniasis Vaccines, SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, GLA-SE, glucopyranosyl lipid adjuvant in stable emulsion, H2B, histone H2B, Recombinant Proteins, 3. Good health, Vaccination, SMT, sterol methyltransferase, Infectious Diseases, Leishmaniasis, Visceral, Molecular Medicine, Female, Adjuvant, TLR, Toll-like receptor, Antigens, Protozoan, Biology, Article, 03 medical and health sciences, Antigen, Immunology and Microbiology(all), Escherichia coli, medicine, Animals, Humans, Protozoa, General Veterinary, General Immunology and Microbiology, CL, cutaneous leishmaniasis, Protein, Public Health, Environmental and Occupational Health, T cell, MDH, malate dehydrogenase, Th1 Cells, medicine.disease, biology.organism_classification, veterinary(all), Virology, Fusion protein, Mice, Inbred C57BL, 030104 developmental biology, Visceral leishmaniasis, Immunology, VL, visceral leishmaniasis, biology.protein, Vaccine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1330152f16af4428ac9203f0df3213
https://doi.org/10.1016/j.vaccine.2016.04.067

المؤلفون: José António Araújo Pinto, A. S. Silva, Francisca Rocha Aguiar, António Carlos Eugénio Megre Sarmento, João Paulo Branco Calheiros Figueiredo Dias, João Nuak

المصدر: IDCases
IDCases, Vol 2, Iss 4, Pp 102-105 (2015)

مصطلحات موضوعية: medicine.medical_specialty, CT, computerized tomography, LDH, lactic dehydrogenase, Fever, Anti-nuclear antibody, ENA, anti-extractable nuclear antigens, medicine.medical_treatment, Hepatosplenomegaly, Case Report, Infectious and parasitic diseases, RC109-216, SLE, systemic lupus erythematosus, PCR, polymerase chain reaction, Systemic lupus erythematosus, WBC, white blood cell count, medicine, PCP, primary care physician, AmB, amphotericin B, ESR, erythrocyte sedimentation rate, LAB, liposomal amphotericin B, Visceral leishmaniasis, biology, business.industry, ID, infectious diseases, ANA, anti-nuclear antibodies, Immunosuppression, CMV, cytomegalovirus, biology.organism_classification, medicine.disease, Pancytopenia, Dermatology, HIV, human immunodeficiency virus, Infectious Diseases, Immunology, RNA, ribonucleic acid, VL, visceral leishmaniasis, dsDNA, double-stranded deoxyribonucleic acid, EBV, Epstein–Barr virus, Leishmania infantum, medicine.symptom, business, Rare disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8ad7c224c9022b5c807997712234ec

المؤلفون: Rosa M. Reguera, Christopher Fernandez-Prada, Raquel Álvarez-Velilla, Rafael Balaña-Fouce, Carlos García-Estrada

المصدر: International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 326-337 (2014)

مصطلحات موضوعية: Drug, Chagas disease, Top, DNA topoisomerase, Tritryps, media_common.quotation_subject, Virulence, NTD, neglected tropical diseases, Biology, Trypanosoma brucei, lcsh:Infectious and parasitic diseases, chemistry.chemical_compound, medicine, Chemotherapy, Pharmacology (medical), lcsh:RC109-216, Trypanosoma cruzi, kDNA, kinetoplast DNA, media_common, ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, Genetics, Invited Review, Drug discovery, CL, cutaneous leishmaniasis, Topoisomerase, Topoisomerases, NGO, non-governmental organization, Kinetoplastids, biology.organism_classification, medicine.disease, NLS, Nuclear Localization Signal, DNA topology, Target-based drug discovery, Infectious Diseases, chemistry, DALYs, disability-adjusted life years, biology.protein, VL, visceral leishmaniasis, Parasitology, lk, linking number, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c842845cd26abc94afd88be6ea5893

المؤلفون: Rupinder, Kaur, Sukhbir, Kaur

المصدر: Journal of Traditional and Complementary Medicine

مصطلحات موضوعية: SSG, Sodium stibogluconate, PCT, Proximal convoluted tubules, Extract, T.S, Transverse section, DCT, Distal convoluted tubules, VL, Visceral leishmaniasis, Biochemical, Parasite load, Immunological, DMSO, Dimethyl sulphoxide, Histopathological studies, BLEE, Bergenia ligulata ethanolic extract, p.t.d., Post treatment days, p.i.d., Post infection days, Original Article, CMI, Cell mediated immune responses, HPLC, SRBC, Sheep red blood cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8ec44852e8b595345f705285adc1853b
https://pubmed.ncbi.nlm.nih.gov/29322016