المؤلفون: Anliker-Ort M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Hsin CH; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Krause A; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Pfister M; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., van den Anker J; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Kaufmann P; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

المصدر: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Aug; Vol. 11 (4), pp. e01112.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 101626369 Publication Model: Print Cited Medium: Internet ISSN: 2052-1707 (Electronic) Linking ISSN: 20521707 NLM ISO Abbreviation: Pharmacol Res Perspect Subsets: MEDLINE

مواضيع طبية MeSH: Factor Va*, Electrocardiography

المؤلفون: Anliker-Ort M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Delahaye S; Department of Preclinical Drug Metabolism and Pharmacokinetics, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Janů L; CEPHA s.r.o., Pilsen, Czech Republic., van den Anker J; Pediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Berger B; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Kaufmann P; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

المصدر: Clinical and translational science [Clin Transl Sci] 2023 Jul; Vol. 16 (7), pp. 1220-1231. Date of Electronic Publication: 2023 Apr 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

مواضيع طبية MeSH: Factor Va* , Cytochrome P-450 CYP3A*, Humans ; Male ; Midazolam/pharmacokinetics ; Cytochrome P-450 CYP2C19 ; Drug Interactions ; Cytochrome P-450 Enzyme System ; Omeprazole/pharmacokinetics

المؤلفون: Gantseva AR; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology, Institutskiy Pereulok, 9, Dolgoprudny, Moscow Oblast 141701, Russia., Gantseva ER; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie gory, Moscow 119991, Russia., Sveshnikova AN; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow 109029, Russia; National Medical Research Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 1 Samory Mashela St, 117198 Moscow, Russia; Faculty of Fundamental Physical and Chemical Engineering, Lomonosov Moscow State University, GSP-1, 1 Leninskiye Gory, Moscow 119991, Russia., Panteleev MA; Faculty of Physics, Lomonosov Moscow State University, 1/2 Leninskie gory, Moscow 119991, Russia; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow 109029, Russia; National Medical Research Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 1 Samory Mashela St, 117198 Moscow, Russia., Kovalenko TA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., Moscow 109029, Russia; National Medical Research Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, 1 Samory Mashela St, 117198 Moscow, Russia. Electronic address: after-ten@yandex.ru.

المصدر: Journal of theoretical biology [J Theor Biol] 2024 Nov 07; Vol. 594, pp. 111925. Date of Electronic Publication: 2024 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0376342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8541 (Electronic) Linking ISSN: 00225193 NLM ISO Abbreviation: J Theor Biol Subsets: MEDLINE

مواضيع طبية MeSH: Factor Xa*/metabolism , Prothrombin*/metabolism, Kinetics ; Humans ; Models, Biological ; Phospholipids/metabolism ; Blood Coagulation/physiology ; Thrombin/metabolism ; Factor Va/metabolism ; Thromboplastin/metabolism ; Substrate Specificity ; Factor V

المؤلفون: Faundes V; Laboratory of Genetics and Inborn Errors of Metabolism, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.

المصدر: Journal of medicinal food [J Med Food] 2023 Feb; Vol. 26 (2), pp. 162-163. Date of Electronic Publication: 2023 Jan 13.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9812512 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7600 (Electronic) Linking ISSN: 1096620X NLM ISO Abbreviation: J Med Food Subsets: MEDLINE

مواضيع طبية MeSH: Spermidine* , Factor Va*, Eukaryota ; Brain

المؤلفون: Hammann-Hänni A; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Kaufmann P; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Klein G; APEX GmbH, Munich, Germany., Schmid K; APEX GmbH, Munich, Germany., Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

المصدر: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 152-158. Date of Electronic Publication: 2022 Oct 26.

نوع المنشور: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

مواضيع طبية MeSH: Factor Va* , Renal Insufficiency*, Humans ; Area Under Curve

المؤلفون: Anliker-Ort M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.; Paediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Farine H; Translational Biomarkers, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Groenen P; Translational Biomarkers, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Kornberger R; Parexel International GmbH, Berlin, Germany., van den Anker J; Paediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Kaufmann P; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Jan; Vol. 89 (1), pp. 380-389. Date of Electronic Publication: 2022 Sep 07.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Factor Va* , Matrix Metalloproteinase 9*, Female ; Humans ; Male ; Administration, Oral ; Area Under Curve ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drug Administration Schedule ; Healthy Volunteers

المؤلفون: Ort M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.; Paediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Hsin CH; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Richard M; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Huehn E; Department of Preclinical Drug Metabolism and Pharmacokinetics, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Sabattini G; Department of Preclinical Drug Metabolism and Pharmacokinetics, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., van de Wetering J; PRA Health Sciences, Groningen, The Netherlands., Kornberger R; Parexel International GmbH, Berlin, Germany., van den Anker J; Paediatric Pharmacology and Pharmacometrics, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland., Kaufmann P; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.

المصدر: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2022 Aug; Vol. 131 (2), pp. 114-128. Date of Electronic Publication: 2022 Jun 08.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial

بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Factor Va*/adverse effects , Factor Va*/pharmacokinetics , Factor Va*/pharmacology, Administration, Oral ; Animals ; Area Under Curve ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Healthy Volunteers ; Humans ; Male

المؤلفون: Soule EE; Department of Pharmacology & Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA., Yu H; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA., Olson L; Department of Pharmacology & Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA., Naqvi I; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA., Kumar S; The Children's Hospital of Philadelphia, Division of Hematology, Department of Pediatrics, The University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA., Krishnaswamy S; The Children's Hospital of Philadelphia, Division of Hematology, Department of Pediatrics, The University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA., Sullenger BA; Department of Pharmacology & Cancer Biology, Duke University, Durham, NC 27710, USA; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: bruce.sullenger@duke.edu.

المصدر: Cell chemical biology [Cell Chem Biol] 2022 Feb 17; Vol. 29 (2), pp. 215-225.e5. Date of Electronic Publication: 2022 Feb 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Anticoagulants/*pharmacology , Aptamers, Nucleotide/*pharmacology , Blood Coagulation/*drug effects , Factor V/*antagonists & inhibitors , Factor Va/*antagonists & inhibitors, Amino Acid Sequence ; Anticoagulants/chemistry ; Anticoagulants/metabolism ; Aptamers, Nucleotide/chemistry ; Aptamers, Nucleotide/metabolism ; Base Pairing ; Binding Sites ; COVID-19/blood ; Cell Membrane/chemistry ; Cell Membrane/metabolism ; Factor V/chemistry ; Factor V/genetics ; Factor V/metabolism ; Factor Va/chemistry ; Factor Va/genetics ; Factor Va/metabolism ; Heparin, Low-Molecular-Weight/chemistry ; Heparin, Low-Molecular-Weight/metabolism ; Humans ; Immune Sera/chemistry ; Immune Sera/metabolism ; Models, Molecular ; Nucleic Acid Conformation ; Protamines ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; SARS-CoV-2/growth & development ; SARS-CoV-2/pathogenicity ; SELEX Aptamer Technique ; Substrate Specificity ; COVID-19 Drug Treatment

المؤلفون: Wu, J., Ai, X., Zheng, Y., Xu, Z., Zhao, F.

المصدر: IEEE Transactions on Aerospace and Electronic Systems IEEE Trans. Aerosp. Electron. Syst. Aerospace and Electronic Systems, IEEE Transactions on. 60(4):4295-4309 Aug, 2024

المؤلفون: Mach, Pavel, Pelikanova, Ivana, Rohlena, Jaroslav

المصدر: 2024 47th International Spring Seminar on Electronics Technology (ISSE) Electronics Technology (ISSE), 2024 47th International Spring Seminar on. 2024:1-4 May, 2024

Relation: 2024 47th International Spring Seminar on Electronics Technology (ISSE)