المؤلفون: Abdul-Ridha A; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia., de Zhang LA; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia., Betrie AH; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia., Deluigi M; Department of Biochemistry, University of Zurich, CH-8057 Zurich, Switzerland., Vaid TM; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia.; The Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria 3010, Australia.; The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Whitehead A; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia., Zhang Y; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia., Davis B; Vernalis (R&D) Ltd, Granta Park, Cambridge CB21 6GB, U.K., Harris R; Vernalis (R&D) Ltd, Granta Park, Cambridge CB21 6GB, U.K., Simmonite H; Vernalis (R&D) Ltd, Granta Park, Cambridge CB21 6GB, U.K., Hubbard RE; Vernalis (R&D) Ltd, Granta Park, Cambridge CB21 6GB, U.K.; Department of Chemistry, University of York, York YO10 5DD, U.K., Gooley PR; The Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria 3010, Australia.; The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Plückthun A; Department of Biochemistry, University of Zurich, CH-8057 Zurich, Switzerland., Bathgate RAD; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia.; The Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria 3010, Australia., Chalmers DK; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia., Scott DJ; The Florey Institute, The University of Melbourne, 30 Royal Parade, Parkville, Victoria 3052, Australia.; The Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, Victoria 3010, Australia.

المصدر: ACS chemical neuroscience [ACS Chem Neurosci] 2024 Feb 07; Vol. 15 (3), pp. 671-684. Date of Electronic Publication: 2024 Jan 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Adrenergic, alpha-1*/metabolism , Prazosin*, Tamsulosin ; Norepinephrine

المؤلفون: Vaid TM; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Avenue, Chicago, Illinois 60607, United States., Demissie R; Biophysics Core at Research Resource Center, University of Illinois at Chicago, 1100 S. Ashland Avenue, Chicago, Illinois 60607, United States., Kwon Y; Biophysics Core at Research Resource Center, University of Illinois at Chicago, 1100 S. Ashland Avenue, Chicago, Illinois 60607, United States., Tran T; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Avenue, Chicago, Illinois 60607, United States.; Biophysics Core at Research Resource Center, University of Illinois at Chicago, 1100 S. Ashland Avenue, Chicago, Illinois 60607, United States., Moon HG; Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Villegas JA; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Avenue, Chicago, Illinois 60607, United States., Park GY; Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, United States., Johnson ME; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Avenue, Chicago, Illinois 60607, United States., Lee H; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Avenue, Chicago, Illinois 60607, United States.; Biophysics Core at Research Resource Center, University of Illinois at Chicago, 1100 S. Ashland Avenue, Chicago, Illinois 60607, United States.

المصدر: ACS omega [ACS Omega] 2023 Jun 01; Vol. 8 (23), pp. 20505-20512. Date of Electronic Publication: 2023 Jun 01 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE

المؤلفون: Lee H; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60607, USA; Biophysics Core at Research Resource Center, University of Illinois at Chicago, Chicago, IL 60607, USA., Youn I; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60607, USA., Demissie R; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60607, USA; Biophysics Core at Research Resource Center, University of Illinois at Chicago, Chicago, IL 60607, USA., Vaid TM; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60607, USA., Che CT; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60607, USA., Azar DT; Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL 60612, USA., Han KY; Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL 60612, USA. Electronic address: biohan72@uic.edu.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 May 01; Vol. 85, pp. 117289. Date of Electronic Publication: 2023 Apr 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Screening Assays* , Clioquinol*, Humans ; Matrix Metalloproteinase 14 ; Matrix Metalloproteinase Inhibitors/chemistry ; Matrix Metalloproteinases/metabolism

المؤلفون: Villegas JA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA., Vaid TM; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA., Johnson ME; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA.; Center for Biomolecular Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60606, USA., Moore TW; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, IL 60612, USA.; University of Illinois Cancer Center, University of Illinois Chicago, Chicago, IL 60612, USA.

المصدر: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2023 Mar 02; Vol. 21, pp. 1885-1892. Date of Electronic Publication: 2023 Mar 02 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology Country of Publication: Netherlands NLM ID: 101585369 Publication Model: eCollection Cited Medium: Print ISSN: 2001-0370 (Print) Linking ISSN: 20010370 NLM ISO Abbreviation: Comput Struct Biotechnol J Subsets: PubMed not MEDLINE

المؤلفون: Ren J; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Ave, Chicago, IL, 60607, USA.; BeiGene (Beijing) Co., Ltd, No. 30 Science Park Road, Zhong-Guan-Cun Life Sciences Park, Changping District, Beijing, 102206, People's Republic of China., Vaid TM; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Ave, Chicago, IL, 60607, USA., Lee H; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Ave, Chicago, IL, 60607, USA.; Biophysics Core at Research Resource Center, University of Illinois at Chicago, 1100 S. Ashland Ave, Chicago, IL, 60607, USA., Ojeda I; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Ave, Chicago, IL, 60607, USA., Johnson ME; Center for Biomolecular Sciences and Department of Pharmaceutical Sciences, University of Illinois at Chicago, 900 S. Ashland Ave, Chicago, IL, 60607, USA. mjohnson@uic.edu.

المصدر: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2023 Jan; Vol. 37 (1), pp. 53-65. Date of Electronic Publication: 2022 Nov 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4951 (Electronic) Linking ISSN: 0920654X NLM ISO Abbreviation: J Comput Aided Mol Des Subsets: MEDLINE

مواضيع طبية MeSH: Hepacivirus* , Hepatitis C*/drug therapy, Humans ; Molecular Dynamics Simulation ; Molecular Docking Simulation ; Protease Inhibitors/pharmacology ; Viral Nonstructural Proteins/chemistry ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry

المؤلفون: Deluigi M; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Morstein L; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Schuster M; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Klenk C; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Merklinger L; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.; Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, 2800 Kgs, Lyngby, Denmark., Cridge RR; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia., de Zhang LA; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia.; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, VIC, 3010, Australia., Klipp A; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, Vladimir-Prelog-Weg 1-5/10, CH-8093, Zurich, Switzerland., Vacca S; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Vaid TM; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL, USA., Mittl PRE; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Egloff P; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Eberle SA; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Zerbe O; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland., Chalmers DK; Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia., Scott DJ; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia. daniel.scott@florey.edu.au.; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, VIC, 3010, Australia. daniel.scott@florey.edu.au., Plückthun A; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland. plueckthun@bioc.uzh.ch.

المصدر: Nature communications [Nat Commun] 2022 Jan 19; Vol. 13 (1), pp. 382. Date of Electronic Publication: 2022 Jan 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Crystallography, X-Ray*, Receptors, Adrenergic, alpha-1/*chemistry, Binding Sites ; HEK293 Cells ; Humans ; Ligands ; Lipids/chemistry ; Models, Molecular ; Quinazolines/chemistry ; Quinazolines/metabolism ; Quinoxalines/chemistry ; Quinoxalines/metabolism ; Receptors, Adrenergic, alpha-2/chemistry

المؤلفون: Vaid TM; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, 3010, VIC, Australia.; Bio21 Molecular Science & Biotechnology Institute, University of Melbourne, Parkville, 3010, VIC, Australia.; The Florey Institute of Neuroscience & Mental Health, University of Melbourne, Parkville, 3015, VIC, Australia., Chalmers DK; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, 3052, VIC, Australia., Scott DJ; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, 3010, VIC, Australia.; The Florey Institute of Neuroscience & Mental Health, University of Melbourne, Parkville, 3015, VIC, Australia., Gooley PR; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, 3010, VIC, Australia.; Bio21 Molecular Science & Biotechnology Institute, University of Melbourne, Parkville, 3010, VIC, Australia.

المصدر: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Sep 10; Vol. 26 (51), pp. 11796-11805. Date of Electronic Publication: 2020 Aug 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

مواضيع طبية MeSH: Epinephrine/*chemistry , Receptors, Adrenergic, alpha-1/*chemistry , Receptors, G-Protein-Coupled/*chemistry, Ligands ; Magnetic Resonance Spectroscopy ; Receptors, Adrenergic, alpha-1/analysis ; Receptors, Adrenergic, alpha-1/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Signal Transduction

المؤلفون: Wu FJ; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville 3052, VIC, Australia; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville 3052, VIC, Australia; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Williams LM; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Abdul-Ridha A; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Gunatilaka A; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Vaid TM; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville 3052, VIC, Australia; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville 3052, VIC, Australia; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Kocan M; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Whitehead AR; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Griffin MDW; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville 3052, VIC, Australia; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville 3052, VIC, Australia., Bathgate RAD; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville 3052, VIC, Australia; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia., Scott DJ; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville 3052, VIC, Australia; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3052, VIC, Australia. Electronic address: daniel.scott@florey.edu.au., Gooley PR; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville 3052, VIC, Australia; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville 3052, VIC, Australia. Electronic address: prg@unimelb.edu.au.

المصدر: The Journal of biological chemistry [J Biol Chem] 2020 May 22; Vol. 295 (21), pp. 7404-7417. Date of Electronic Publication: 2020 Apr 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Adrenergic, alpha-1/*chemistry, Allosteric Regulation ; Crystallography, X-Ray ; Humans ; Ligands ; Nuclear Magnetic Resonance, Biomolecular ; Protein Conformation ; Receptors, Adrenergic, alpha-1/metabolism

المؤلفون: Bumbak F; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia.; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Thomas T; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Noonan-Williams BJ; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Vaid TM; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia.; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia., Yan F; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Whitehead AR; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia., Bruell S; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia., Kocan M; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia.; The School of BioSciences, The University of Melbourne, Parkville, Victoria 3010, Australia., Tan X; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, Alabama 35294-1240, United States., Johnson MA; Department of Chemistry, The University of Alabama at Birmingham, Birmingham, Alabama 35294-1240, United States., Bathgate RAD; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia.; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia., Chalmers DK; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia., Gooley PR; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3010, Australia., Scott DJ; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria 3010, Australia.; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.

المصدر: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2020 Apr 29; Vol. 3 (4), pp. 690-705. Date of Electronic Publication: 2020 Apr 29 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101721411 Publication Model: eCollection Cited Medium: Internet ISSN: 2575-9108 (Electronic) Linking ISSN: 25759108 NLM ISO Abbreviation: ACS Pharmacol Transl Sci Subsets: PubMed not MEDLINE

المؤلفون: Williams LM; The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia., He X; The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia.; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute University of Melbourne Parkville Vic Australia., Vaid TM; The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia.; Department of Biochemistry and Molecular Biology University of Melbourne Parkville Vic Australia.; The Bio21 Molecular Science and Biotechnology Institute University of Melbourne Parkville Vic Australia., Abdul-Ridha A; The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia., Whitehead AR; The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia., Gooley PR; Department of Biochemistry and Molecular Biology University of Melbourne Parkville Vic Australia.; The Bio21 Molecular Science and Biotechnology Institute University of Melbourne Parkville Vic Australia., Bathgate RAD; The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia.; Department of Biochemistry and Molecular Biology University of Melbourne Parkville Vic Australia., Williams SJ; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute University of Melbourne Parkville Vic Australia.; The Bio21 Molecular Science and Biotechnology Institute University of Melbourne Parkville Vic Australia., Scott DJ; The Florey Institute of Neuroscience and Mental Health University of Melbourne Parkville Vic Australia.; Department of Biochemistry and Molecular Biology University of Melbourne Parkville Vic Australia.

المصدر: Pharmacology research & perspectives [Pharmacol Res Perspect] 2018 Dec 26; Vol. 7 (1), pp. e00455. Date of Electronic Publication: 2018 Dec 26 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 101626369 Publication Model: eCollection Cited Medium: Internet ISSN: 2052-1707 (Electronic) Linking ISSN: 20521707 NLM ISO Abbreviation: Pharmacol Res Perspect Subsets: MEDLINE

مواضيع طبية MeSH: Cyclic Nucleotide Phosphodiesterases, Type 4/*metabolism , Diazepam/*pharmacology , Phosphodiesterase 4 Inhibitors/*pharmacology , Receptors, Adrenergic, alpha-1/*metabolism, Allosteric Regulation/drug effects ; Animals ; Binding Sites/drug effects ; COS Cells ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Magnetic Resonance Spectroscopy ; Receptors, Adrenergic, alpha-1/chemistry