المؤلفون: Valcourt JR; Systems, Synthetic, and Quantitative Biology Program, Harvard University, Cambridge, MA 02138, USA; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA; Division of Applied Physics, Harvard University, Cambridge, MA 02138, USA. Electronic address: valcourt@alumni.harvard.edu., Huang RE; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA; Division of Applied Physics, Harvard University, Cambridge, MA 02138, USA., Kundu S; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Venkatasubramanian D; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA; Division of Applied Physics, Harvard University, Cambridge, MA 02138, USA., Kingston RE; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Ramanathan S; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA; Division of Applied Physics, Harvard University, Cambridge, MA 02138, USA; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: sharad@cgr.harvard.edu.

المصدر: Cell reports [Cell Rep] 2021 Nov 09; Vol. 37 (6), pp. 109990.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cell Lineage* , Gene Expression Regulation, Developmental*, Germ Layers/*cytology , Human Embryonic Stem Cells/*cytology , Mesoderm/*cytology , Octamer Transcription Factor-3/*metabolism , SOXB1 Transcription Factors/*metabolism, Cell Differentiation ; Gene Expression Profiling ; Gene Regulatory Networks ; Germ Layers/metabolism ; Human Embryonic Stem Cells/metabolism ; Humans ; Mesoderm/metabolism ; Octamer Transcription Factor-3/genetics ; RNA-Seq ; SOXB1 Transcription Factors/genetics

المؤلفون: Bokoch MP; Cardiovascular Research Institute , University of California , San Francisco , California 94158 , United States.; Department of Anesthesia and Perioperative Care , University of California , San Francisco , California 94143 , United States., Jo H; Department of Pharmaceutical Chemistry , University of California , San Francisco , California 94143 , United States., Valcourt JR; D. E. Shaw Research , New York , New York 10036 , United States., Srinivasan Y; Cardiovascular Research Institute , University of California , San Francisco , California 94158 , United States., Pan AC; D. E. Shaw Research , New York , New York 10036 , United States., Capponi S; Cardiovascular Research Institute , University of California , San Francisco , California 94158 , United States., Grabe M; Cardiovascular Research Institute , University of California , San Francisco , California 94158 , United States., Dror RO; D. E. Shaw Research , New York , New York 10036 , United States., Shaw DE; D. E. Shaw Research , New York , New York 10036 , United States.; Department of Biochemistry and Molecular Biophysics , Columbia University , New York , New York 10032 , United States., DeGrado WF; Department of Pharmaceutical Chemistry , University of California , San Francisco , California 94143 , United States., Coughlin SR; Cardiovascular Research Institute , University of California , San Francisco , California 94158 , United States.

المصدر: Biochemistry [Biochemistry] 2018 Oct 02; Vol. 57 (39), pp. 5748-5758. Date of Electronic Publication: 2018 Aug 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Lactones/*metabolism , Lipid Bilayers/*metabolism , Pyridines/*metabolism , Receptor, PAR-1/*antagonists & inhibitors , Receptor, PAR-1/*metabolism, Animals ; Binding Sites ; Fibroblasts ; Humans ; Lactones/chemistry ; Ligands ; Molecular Dynamics Simulation ; Molecular Structure ; Phosphatidylcholines/metabolism ; Protein Binding ; Protein Conformation ; Pyridines/chemistry ; Rats ; Receptor, PAR-1/chemistry

المؤلفون: Dror RO; 1] D. E. Shaw Research, 120 West 45th Street, 39th Floor, New York, New York 10036, USA [2]., Green HF, Valant C, Borhani DW, Valcourt JR, Pan AC, Arlow DH, Canals M, Lane JR, Rahmani R, Baell JB, Sexton PM, Christopoulos A, Shaw DE

المصدر: Nature [Nature] 2013 Nov 14; Vol. 503 (7475), pp. 295-9. Date of Electronic Publication: 2013 Oct 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Receptors, G-Protein-Coupled/*antagonists & inhibitors , Receptors, G-Protein-Coupled/*chemistry, Allosteric Regulation/physiology ; Animals ; Binding Sites ; CHO Cells ; Cricetulus ; Humans ; Models, Chemical ; Molecular Conformation ; Molecular Dynamics Simulation ; Mutation ; Protein Binding ; Receptors, G-Protein-Coupled/genetics ; Reproducibility of Results

المؤلفون: Valcourt JR; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Lemons JM, Haley EM, Kojima M, Demuren OO, Coller HA

المصدر: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2012 May 01; Vol. 11 (9), pp. 1680-96. Date of Electronic Publication: 2012 May 01.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-4005 (Electronic) Linking ISSN: 15514005 NLM ISO Abbreviation: Cell Cycle Subsets: MEDLINE

مواضيع طبية MeSH: Adaptation, Physiological* , Cell Cycle Checkpoints*, Escherichia coli/*metabolism , Hematopoietic Stem Cells/*metabolism , Saccharomyces cerevisiae/*metabolism, Animals ; Autophagy ; Cell Proliferation ; Escherichia coli/cytology ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Glucose/metabolism ; Glycolysis ; Hematopoietic Stem Cells/cytology ; Humans ; Lymphocyte Activation ; Phosphatidylinositol 3-Kinase/metabolism ; Saccharomyces cerevisiae/cytology ; Signal Transduction ; T-Lymphocytes/cytology ; T-Lymphocytes/metabolism ; TOR Serine-Threonine Kinases/metabolism