المؤلفون: Byrnes C; The Emmes Company, LLC, 401 North Washington Street, Suite 700, Rockville, MD 20850. Electronic address: cbyrnes@emmes.com., Botello-Harbaum M; The Emmes Company, LLC, 401 North Washington Street, Suite 700, Rockville, MD 20850. Electronic address: marbotel3@aol.com., Clemons T; The Emmes Company, LLC, 401 North Washington Street, Suite 700, Rockville, MD 20850. Electronic address: tclemons@emmes.com., Bailey L; Sickle Cell Consortium, Inc., P.O. Box 1195, Cumming, GA 30028. Electronic address: director@sicklecellconsortium.org., Valdes KM; National Heart Lung and Blood Institute, National Institutes of Health, 6705 Rockledge Dr, Bethesda MD 20817. Electronic address: k.valdes4513@gmail.com., Coleman-Cowger VH; The Emmes Company, LLC, 401 North Washington Street, Suite 700, Rockville, MD 20850. Electronic address: vcolemancowger@emmes.com.

المصدر: Journal of the National Medical Association [J Natl Med Assoc] 2022 Apr; Vol. 114 (2), pp. 211-217. Date of Electronic Publication: 2022 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7503090 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1943-4693 (Electronic) Linking ISSN: 00279684 NLM ISO Abbreviation: J Natl Med Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Anemia, Sickle Cell*/therapy , Clinical Trials as Topic* , Patient Participation*, Genetic Therapy ; Humans ; United States

المؤلفون: Hockberger P; Northwestern University, Evanston, IL, USA. p-hockberger@northwestern.edu.; Chicago Biomedical Innovation Alliance (CBIA), Chicago, IL, USA. p-hockberger@northwestern.edu., Valdes KM; Women In Bio, Sea Island, GA, USA., Bosc J; Women In Bio, Sea Island, GA, USA., Iadicicco L; Women In Bio, Sea Island, GA, USA., Georganopoulou D; Women In Bio, Sea Island, GA, USA.

المصدر: Nature biotechnology [Nat Biotechnol] 2021 Apr; Vol. 39 (4), pp. 523-525.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Perry ME; Office of Strategic Coordination, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA., Valdes KM; National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Bethesda, MD, USA., Wilder E; Office of Strategic Coordination, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA., Austin CP; National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Bethesda, MD, USA., Brooks PJ; National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Bethesda, MD, USA.

المصدر: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2018 Oct; Vol. 17 (10), pp. 689-690. Date of Electronic Publication: 2018 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1784 (Electronic) Linking ISSN: 14741776 NLM ISO Abbreviation: Nat Rev Drug Discov Subsets: MEDLINE

مواضيع طبية MeSH: Genome, Human/*genetics, Animals ; Gene Editing/methods ; Genetic Therapy/methods ; Humans ; Mutation/genetics

المؤلفون: Li K; Division of Vascular and Endovascular Surgery, Department of Surgery, University of California, San Francisco, and Veterans Affairs Medical Center, San Francisco, California, USA., Rodosthenous RS; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Kashanchi F; Laboratory of Molecular Virology, National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA., Gingeras T; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA., Gould SJ; Department of Biological Chemistry, Johns Hopkins University, Baltimore, Maryland, USA., Kuo LS; National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA., Kurre P; Doernbecher Children's Hospital, Department of Pediatrics and Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, Oregon, USA., Lee H; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, USA., Leonard JN; Department of Chemical and Biological Engineering, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, USA., Liu H; Departments of Pharmacology and Medicine (Hematology and Oncology), Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Lombo TB; NIH, Office of the Director, Environmental Influences on Child Health Outcomes Program, Bethesda, Maryland, USA., Momma S; Institute of Neurology (Edinger Institute), Frankfurt University Medical School, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Frankfurt, Heidelberg, Germany., Nolan JP; Scintillon Institute, San Diego, California, USA., Ochocinska MJ; National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland, USA., Pegtel DM; Department of Pathology, Cancer Center Amsterdam, Vrije Universiteit (VU) University Medical Center, Amsterdam, The Netherlands., Sadovsky Y; Magee-Womens Research Institute, Department of Microbiology and Molecular Genetics, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Sánchez-Madrid F; Instituto de Investigación Sanitaria Princesa, Hospital Universitario de la Princesa, Universidad Autónoma de Madrid, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Valdes KM; National Center for Advancing Translational Science, Bethesda, Maryland, USA., Vickers KC; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Weaver AM; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Witwer KW; Department of Molecular and Comparative Pathobiology, Department of Neurology, The Johns Hopkins University, Baltimore, Maryland, USA., Zeng Y; Department of Chemistry, University of Kansas Cancer Center, Lawrence, Kansas, USA., Das S; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Raffai RL; Division of Vascular and Endovascular Surgery, Department of Surgery, University of California, San Francisco, and Veterans Affairs Medical Center, San Francisco, California, USA., Howcroft TK; Cancer Immunology, Hematology, and Etiology Branch, Division of Cancer Biology, National Cancer Institute, Bethesda, Maryland, USA.

المصدر: JCI insight [JCI Insight] 2018 Apr 05; Vol. 3 (7). Date of Electronic Publication: 2018 Apr 05 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Cell Communication/*genetics , Extracellular Space/*metabolism , Gene Expression Regulation/*immunology , RNA/*metabolism, Animals ; Cell Communication/immunology ; Congresses as Topic ; Disease Models, Animal ; Extracellular Space/genetics ; Extracellular Space/immunology ; Humans ; National Institutes of Health (U.S.) ; RNA/immunology ; Translational Research, Biomedical/methods ; United States

المؤلفون: Valdes KM; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park (UMCP), College Park, Maryland, USA., Sundar GS; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park (UMCP), College Park, Maryland, USA., Belew AT; Center for Bioinformatics and Computation Biology, UMCP, College Park, MD, USA., Islam E; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park (UMCP), College Park, Maryland, USA., El-Sayed NM; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park (UMCP), College Park, Maryland, USA.; Center for Bioinformatics and Computation Biology, UMCP, College Park, MD, USA., Le Breton Y; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park (UMCP), College Park, Maryland, USA. lebreton@umd.edu., McIver KS; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park (UMCP), College Park, Maryland, USA. kmciver@umd.edu.

المصدر: Scientific reports [Sci Rep] 2018 Mar 21; Vol. 8 (1), pp. 4971. Date of Electronic Publication: 2018 Mar 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Blood Glucose/*immunology , Gene Expression Regulation, Bacterial/*immunology , Regulon/*immunology , Streptococcal Infections/*immunology , Streptococcus pyogenes/*pathogenicity, Bacterial Proteins/genetics ; Bacterial Proteins/immunology ; Bacterial Proteins/metabolism ; Blood Glucose/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Bacterial/genetics ; Humans ; Phosphotransferases ; Sequence Analysis, RNA ; Streptococcal Infections/blood ; Streptococcal Infections/microbiology ; Streptococcus pyogenes/genetics ; Streptococcus pyogenes/immunology ; Virulence/genetics ; Virulence/immunology ; Virulence Factors/genetics ; Virulence Factors/immunology ; Virulence Factors/metabolism

المؤلفون: Vega LA; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Valdes KM; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Sundar GS; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Belew AT; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Islam E; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Berge J; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Curry P; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Chen S; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., El-Sayed NM; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA.; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA., Le Breton Y; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA lebreton@umd.edu kmciver@umd.edu., McIver KS; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA lebreton@umd.edu kmciver@umd.edu.

المصدر: Infection and immunity [Infect Immun] 2017 Feb 23; Vol. 85 (3). Date of Electronic Publication: 2017 Feb 23 (Print Publication: 2017).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0246127 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5522 (Electronic) Linking ISSN: 00199567 NLM ISO Abbreviation: Infect Immun Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate*, Bacterial Proteins/*genetics , Host-Pathogen Interactions/*immunology , Streptococcal Infections/*immunology , Streptococcal Infections/*microbiology , Streptococcus pyogenes/*physiology , Transcription Factors/*genetics, Animals ; Disease Models, Animal ; Humans ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/microbiology ; Mice ; Microbial Viability ; Mutation ; Neutrophils/immunology ; Neutrophils/metabolism ; Neutrophils/microbiology ; Streptococcal Infections/metabolism ; Streptococcal Infections/mortality ; Virulence

المؤلفون: Valdes KM; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Sundar GS; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Vega LA; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Belew AT; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA.; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA., Islam E; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Binet R; Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA., El-Sayed NM; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA.; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA., Le Breton Y; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA lebreton@umd.edu kmciver@umd.edu., McIver KS; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA lebreton@umd.edu kmciver@umd.edu.

المصدر: Infection and immunity [Infect Immun] 2016 Mar 24; Vol. 84 (4), pp. 1016-1031. Date of Electronic Publication: 2016 Mar 24 (Print Publication: 2016).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0246127 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5522 (Electronic) Linking ISSN: 00199567 NLM ISO Abbreviation: Infect Immun Subsets: MEDLINE

مواضيع طبية MeSH: Blood/*microbiology , Fructose/*metabolism , Neutrophils/*physiology , Operon/*physiology , Streptococcus pyogenes/*physiology, Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Blood Bactericidal Activity/physiology ; Chromosome Mapping ; Chromosomes, Bacterial ; Female ; Gene Expression Regulation, Bacterial ; Humans ; Mice ; Mutation ; Streptococcal Infections/microbiology

المؤلفون: Le Breton Y, Belew AT, Valdes KM, Islam E, Curry P, Tettelin H; 1] [2]., Shirtliff ME; 1] [2]., El-Sayed NM; 1] [2]., McIver KS

المصدر: Scientific reports [Sci Rep] 2015 May 21; Vol. 5, pp. 9838. Date of Electronic Publication: 2015 May 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Genome, Bacterial*, Streptococcus pyogenes/*genetics, Bayes Theorem ; Biosynthetic Pathways/genetics ; Genes, Essential ; Glycolysis/genetics ; Humans ; Sequence Analysis, DNA ; Streptococcus pyogenes/isolation & purification

المؤلفون: Le Breton Y; Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA., Mistry P, Valdes KM, Quigley J, Kumar N, Tettelin H, McIver KS

المصدر: Infection and immunity [Infect Immun] 2013 Mar; Vol. 81 (3), pp. 862-75. Date of Electronic Publication: 2013 Jan 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0246127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5522 (Electronic) Linking ISSN: 00199567 NLM ISO Abbreviation: Infect Immun Subsets: MEDLINE

مواضيع طبية MeSH: Blood/*microbiology , Gene Expression Regulation, Bacterial/*physiology , Genome, Bacterial/*genetics , Streptococcus pyogenes/*genetics, Chromosome Mapping ; Chromosomes, Bacterial ; Genetic Fitness ; Hemolysin Proteins/genetics ; Hemolysin Proteins/metabolism ; Humans ; Mutagenesis, Insertional ; Mutation