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1
المؤلفون: David R. Langley, Brian Carpenter, Valentina Goldfarb, William J. Metzler, Susan E. Kiefer, Walter Kostich, Mian Gao, Kevin Kish, Ryan Westphal, Patricia A. McDonnell, Steven Sheriff, James William Bryson
المصدر: Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67:768-774
مصطلحات موضوعية: Molecular Sequence Data, Biophysics, Receptor-Like Protein Tyrosine Phosphatases, Protein tyrosine phosphatase, Biology, Crystallography, X-Ray, Biochemistry, law.invention, Crystal, Structural Biology, law, Catalytic Domain, Genetics, Humans, Amino Acid Sequence, Cloning, Molecular, Tyrosine, Crystallization, Ligand, Condensed Matter Physics, Crystallography, Crystallization Communications, Orthorhombic crystal system, Monoclinic crystal system
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2
المؤلفون: Dianlin Xie, Ning Yan, Matthew D. Healy, Keith L. Constantine, Joseph Yanchunas, Brian A. Dougherty, Li Tao, Jane A. Thanassi, Bennett T. Farmer, Stanley R. Krystek, Michael L. Doyle, Valentina Goldfarb, Nathan O. Siemers
المصدر: Protein Science. 14:1472-1484
مصطلحات موضوعية: biology, Stereochemistry, Chemistry, Molecular Sequence Data, Active site, Sequence alignment, Methyltransferases, computer.file_format, Protein structure prediction, Protein Data Bank, Biochemistry, Article, Protein Structure, Tertiary, Streptococcus pneumoniae, Protein structure, Bacterial Proteins, Structural Homology, Protein, Essential gene, biology.protein, Amino Acid Sequence, Molecular Biology, computer, Peptide sequence, Protein secondary structure
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3
المؤلفون: Ronald E. Rose, Michael Wittekind, David R. Langley, Jacques Friborg, Kevin Kish, Qi Guo, Valentina Goldfarb, Herbert E. Klei, Pin-Fang M. Lin, Yaqun Zhang, Steven Sheriff
المصدر: Journal of Virology. 81:9525-9535
مصطلحات موضوعية: Models, Molecular, Pyridines, Peptidomimetic, medicine.medical_treatment, Atazanavir Sulfate, Immunology, Mutant, Biology, Crystallography, X-Ray, Microbiology, Protein structure, HIV Protease, Virology, Vaccines and Antiviral Agents, Drug Resistance, Viral, Hydrolase, medicine, chemistry.chemical_classification, Protease, virus diseases, HIV Protease Inhibitors, Protein Structure, Tertiary, Atazanavir, Enzyme, Biochemistry, chemistry, Insect Science, Mutation, Oligopeptides, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8c3c24fb58201b14d92ea4dbf9029b
https://doi.org/10.1128/jvi.02503-05 -
4
المؤلفون: William J. Metzler, Keith L. Constantine, Stephen R. Johnson, Patricia A. McDonnell, Thomas J. Caulfield, David R. Magnin, Richard B. Sulsky, Jeffrey A. Robl, Luciano Mueller, Valentina Goldfarb, David S. Taylor, Bennett T. Farmer, Rex A. Parker, Leonard P. Adam
المصدر: Journal of Medicinal Chemistry. 49:5013-5017
مصطلحات موضوعية: Keratinocytes, Models, Molecular, Binding Sites, Magnetic Resonance Spectroscopy, Molecular Structure, Protein family, Molecular model, Chemistry, Stereochemistry, Binding protein, Fatty Acid-Binding Proteins, Ligands, Mandelic acid, Small molecule, Fatty acid-binding protein, chemistry.chemical_compound, Drug Discovery, Benzyl group, Humans, Molecular Medicine, Moiety, Computer Simulation
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5
المؤلفون: and Luciano Mueller, Rex A. Parker, Michael Wittekind, Mark S. Friedrichs, Ching-Hsuen Chu, Keith L. Constantine, Ii‡ Bennett T. Farmer, Valentina Goldfarb, Jamil Haris
المصدر: Biochemistry. 37:7965-7980
مصطلحات موضوعية: Intracellular Fluid, Models, Molecular, Protein Conformation, Stereochemistry, Nerve Tissue Proteins, Fatty Acid-Binding Proteins, Myelin P2 Protein, Biochemistry, Fatty acid-binding protein, Mice, chemistry.chemical_compound, Adipocyte, Adipocytes, Side chain, Animals, Humans, Molecule, Computer Simulation, Muscle, Skeletal, Nuclear Magnetic Resonance, Biomolecular, Nitrogen Isotopes, Chemistry, Tumor Suppressor Proteins, Dynamics (mechanics), Relaxation (NMR), Metabolism, Neoplasm Proteins, Cytosol, Thermodynamics, lipids (amino acids, peptides, and proteins), Carrier Proteins, Fatty Acid-Binding Protein 7, Hydrogen, Protein Binding
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6
المؤلفون: Craig R. Fairchild, John T. Hunt, Stephen R. Johnson, Soong-Hoon Kim, Patricia A. McDonnell, Rajeev S. Bhide, Gerald J. Duke, Luciano Mueller, Michael A. Poss, Keith L. Constantine, Herbert E. Klei, Valentina Goldfarb, William J. Metzler, Kevin Kish
المصدر: Bioorganicmedicinal chemistry letters. 23(14)
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Clinical Biochemistry, Phosphatase, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, N acetylneuraminate, Drug Discovery, Hydrolase, Animals, Humans, Carboxylate, Enzyme Inhibitors, Molecular Biology, Binding Sites, biology, Chemistry, Organic Chemistry, Substrate (chemistry), Active site, Phosphonate, Phosphoric Monoester Hydrolases, Protein Structure, Tertiary, Rats, Molecular Docking Simulation, Kinetics, Enzyme inhibitor, Drug Design, biology.protein, Sialic Acids, Molecular Medicine, Sugar Phosphates
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7
المؤلفون: Thomas B. Lavoie, Claudio Mapelli, Chester A. Meyers, Mariano Barbacid, Valentina Goldfarb, Bennett T. Farmer, Jonglin Tsao, Luciano Mueller, Michael Wittekind, Ki-Ling Suen
المصدر: Biochemistry. 33:13531-13539
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Protein Conformation, Molecular Sequence Data, Nuclear magnetic resonance spectroscopy of nucleic acids, Peptide, Biochemistry, SH3 domain, Mice, Protein structure, Computer Graphics, Side chain, Animals, Guanine Nucleotide Exchange Factors, Amino Acid Sequence, Peptide sequence, Adaptor Proteins, Signal Transducing, GRB2 Adaptor Protein, chemistry.chemical_classification, Binding Sites, Chemistry, Proteins, Nuclear magnetic resonance spectroscopy, Peptide Fragments, Recombinant Proteins, Crystallography, Oligopeptides, Two-dimensional nuclear magnetic resonance spectroscopy, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacd6e30d80d83b4ab895b18f77c3107
https://doi.org/10.1021/bi00250a004 -
8
المؤلفون: Kevin Kish, Joanne J. Bronson, Kingsley K. Appiah, Samuel Gerritz, Carolyn Diane Dzierba, Yanling Huang, Weixu Zhai, Valentina Goldfarb, Shuhao Shi, Patricia A. McDonnell, Shirong Zhu, Mian Gao, John E. Macor, Susan E. Kiefer, Brett R. Beno, Jonathan O’Connell, Walter Kostich, Steven Sheriff, Joseph Yanchunas, Ryan Westphal
المصدر: Journal of medicinal chemistry. 54(19)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Protein Conformation, Phosphatase, Molecular Sequence Data, Protein tyrosine phosphatase, Thiophenes, Crystallography, X-Ray, Ligands, Dephosphorylation, Structure-Activity Relationship, Catalytic Domain, Drug Discovery, Hydrolase, Humans, Amino Acid Sequence, Tyrosine, biology, Ligand, Chemistry, Receptor-Like Protein Tyrosine Phosphatases, Class 5, Active site, Small molecule, biology.protein, Molecular Medicine, Hydrophobic and Hydrophilic Interactions, Protein Binding
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المؤلفون: Luciano Mueller, Keith L. Constantine, Philip D. Jeffrey, Steven Sheriff, Valentina Goldfarb, Mark S. Friedrichs
المصدر: Proteins: Structure, Function, and Genetics. 15:290-311
مصطلحات موضوعية: Models, Molecular, Digoxin, Magnetic Resonance Spectroscopy, Protein Conformation, Hydrogen bond, Chemistry, Relaxation (NMR), Immunoglobulin Variable Region, Hydrogen Bonding, Aromaticity, Nanosecond, Biochemistry, Recombinant Proteins, Accessible surface area, Immunoglobulin Fab Fragments, Crystallography, Molecular dynamics, Microsecond, Nuclear magnetic resonance, X-Ray Diffraction, Heteronuclear molecule, Structural Biology, Thermodynamics, Immunoglobulin Light Chains, Molecular Biology
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المؤلفون: Keith L. Constantine, James Anthony, Valentina Goldfarb, Luciano Mueller, Michael Wittekind, Shi Chung Ng
المصدر: Biochemistry. 31:5033-5043
مصطلحات موضوعية: chemistry.chemical_compound, Heteronuclear molecule, Stereochemistry, Chemistry, Amide, Pulse sequence, Nuclear magnetic resonance spectroscopy, Antiparallel (biochemistry), Biochemistry, Two-dimensional nuclear magnetic resonance spectroscopy, Protein secondary structure, Homonuclear molecule
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ed6333a9ff3bfeeaedf51dbb11375dc
https://doi.org/10.1021/bi00136a017