المؤلفون: Luis A. Williams, David J. Gerber, Amy Elder, Wei Chou Tseng, Valeriya Baru, Nathaniel Delaney-Busch, Christina Ambrosi, Gauri Mahimkar, Vaibhav Joshi, Himali Shah, Karthiayani Harikrishnan, Hansini Upadhyay, Sakthi H. Rajendran, Aishwarya Dhandapani, Joshua Meier, Steven J. Ryan, Caitlin Lewarch, Lauren Black, Julie Douville, Stefania Cinquino, Helen Legakis, Karsten Nalbach, Christian Behrends, Ai Sato, Lorenzo Galluzzi, Timothy W. Yu, Duncan Brown, Sudhir Agrawal, David Margulies, Alan Kopin, Graham T. Dempsey

المصدر: Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 189-203 (2022)

مصطلحات موضوعية: Oligonucleotides: Therapies and Applications, antisense oligonucleotide, TECPR2, human induced pluripotent stem cells, SPG49, HSAN9, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253122001676; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/555fd4156baf47509e8e7211947eb238

المؤلفون: Priyanka Narayan, Grzegorz Sienski, Julia M. Bonner, Yuan-Ta Lin, Jinsoo Seo, Valeriya Baru, Aftabul Haque, Blerta Milo, Leyla A. Akay, Agnese Graziosi, Yelena Freyzon, Dirk Landgraf, William R. Hesse, Julie Valastyan, M. Inmaculada Barrasa, Li-Huei Tsai, Susan Lindquist

المصدر: Cell Reports, Vol 33, Iss 1, Pp 108224- (2020)

مصطلحات موضوعية: apolipoprotein E, Alzheimer's disease, genetic risk factors, PICALM, endocytosis, trafficking, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720312134; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/371d6e17de3e4dcca3170e73f880da3a

المؤلفون: Luis A, Williams, David J, Gerber, Amy, Elder, Wei Chou, Tseng, Valeriya, Baru, Nathaniel, Delaney-Busch, Christina, Ambrosi, Gauri, Mahimkar, Vaibhav, Joshi, Himali, Shah, Karthiayani, Harikrishnan, Hansini, Upadhyay, Sakthi H, Rajendran, Aishwarya, Dhandapani, Joshua, Meier, Steven J, Ryan, Caitlin, Lewarch, Lauren, Black, Julie, Douville, Stefania, Cinquino, Helen, Legakis, Karsten, Nalbach, Christian, Behrends, Ai, Sato, Lorenzo, Galluzzi, Timothy W, Yu, Duncan, Brown, Sudhir, Agrawal, David, Margulies, Alan, Kopin, Graham T, Dempsey

المصدر: Molecular therapy. Nucleic acids. 29

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0f46faf63abd1f4135c97b4442e9dca4
https://pubmed.ncbi.nlm.nih.gov/35860385

المؤلفون: Leyla Anne Akay, Susan Lindquist, Agnese Graziosi, Sebastian Boland, William T. Ralvenius, Valeriya Baru, Aleksandra Alicja Arczewska, Nora Kory, Julia Maeve Bonner, Elana Lockshin, Grzegorz Sienski, Caroline A. Lewis, Priyanka Narayan, Blerta Milo, Manolis Kellis, Liang He, David M. Sabatini, Li-Huei Tsai

المساهمون: Sienski G., Narayan P., Bonner J.M., Kory N., Boland S., Arczewska A.A., Ralvenius W.T., Akay L., Lockshin E., He L., Milo B., Graziosi A., Baru V., Lewis C.A., Kellis M., Sabatini D.M., Tsai L.-H., Lindquist S.

المصدر: Sci Transl Med
PMC

مصطلحات موضوعية: Apolipoprotein E, Lipid metabolism, General Medicine, Lipidome, Biology, Article, Cell biology, medicine.anatomical_structure, Lipid droplet, Lipidomics, mental disorders, medicine, Neuroglia, lipids (amino acids, peptides, and proteins), human activities, Lipid Transport, Intracellular, alzheimer apoe4 apoe3 iPSCs lipid glia

وصف الملف: ELETTRONICO; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4318185a6e20804c536d843839fba1
http://hdl.handle.net/11585/854127

المؤلفون: Julia Maeve Bonner, Susan Lindquist, Leyla Anne Akay, M. Inmaculada Barrasa, Julie S. Valastyan, Agnese Graziosi, Valeriya Baru, Aftabul Haque, Yelena Freyzon, Grzegorz Sienski, William R. Hesse, Li-Huei Tsai, Priyanka Narayan, Yuan-Ta Lin, Jinsoo Seo, Blerta Milo, Dirk Landgraf

المصدر: Cell Reports, Vol 33, Iss 1, Pp 108224-(2020)
Cell Rep
Elsevier

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Endocytic cycle, Apolipoprotein E4, Biology, Endocytosis, General Biochemistry, Genetics and Molecular Biology, Article, PICALM, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Risk Factors, trafficking, mental disorders, genetic risk factors, Humans, endocytosis, Allele, Induced pluripotent stem cell, lcsh:QH301-705.5, apolipoprotein E, Signal transducing adaptor protein, Alzheimer's disease, Cell biology, 030104 developmental biology, lcsh:Biology (General), lipids (amino acids, peptides, and proteins), Stem cell, human activities, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33720e98ac0cff7e832c8e35452f808f
http://www.sciencedirect.com/science/article/pii/S2211124720312134

المؤلفون: Gabriel B, Borja, Himali, Shroff, Hansini, Upadhyay, Pin W, Liu, Valeriya, Baru, Yung-Chih, Cheng, Owen B, McManus, Luis A, Williams, Graham T, Dempsey, Christopher A, Werley

المصدر: Methods in molecular biology (Clifton, N.J.). 2191

مصطلحات موضوعية: Neurons, Optogenetics, Calcium Channels, N-Type, Channelrhodopsins, Synapses, Animals, Humans, Calcium, Synapsins, Synaptic Transmission, Rats, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a8060881a314c8e3cd5a056924005c70
https://pubmed.ncbi.nlm.nih.gov/32865742

المؤلفون: Graham T. Dempsey, Pin W. Liu, Hansini Upadhyay, Gabriel B. Borja, Christopher A. Werley, Valeriya Baru, Himali Shroff, Luis A. Williams, Yung-Chih Cheng, Owen B. McManus

المصدر: Methods in Molecular Biology ISBN: 9781071608296

مصطلحات موضوعية: 0301 basic medicine, biology, Drug discovery, Channelrhodopsin, chemistry.chemical_element, Optogenetics, Neurotransmission, Calcium, Cav2.1, 03 medical and health sciences, Electrophysiology, 030104 developmental biology, 0302 clinical medicine, chemistry, biology.protein, Synaptic signaling, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dfb35627916d5e37a95faa9e16f9544b
https://doi.org/10.1007/978-1-0716-0830-2_8

المؤلفون: Thibaut Imberdis, Frank Soldner, Michel Becuwe, Sepp D. Kohlwein, Yelena Freyzon, Gary P.H. Ho, Aftabul Haque, Tobias C. Walther, Clary B. Clish, Elizabeth Terry-Kantor, Dennis J. Selkoe, Saranna Fanning, Gregory A. Newby, Daniel Termine, Tallie Noble, Nagendran Ramalingam, M. Inmaculada Barrasa, Robert V. Farese, Michael A. Welte, Susan Lindquist, Yali Lou, Jackson Sandoe, Tae-Eun Kim, Harald F. Hofbauer, Silke Nuber, David Pincus, Dirk Landgraf, Rudolf Jaenisch, Supriya Srinivasan, Ulf Dettmer, Valeriya Baru

المساهمون: Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology. Department of Biology, Broad Institute of MIT and Harvard

المصدر: PMC

مصطلحات موضوعية: Parkinson's disease, Pharmacology, Antiparkinson Agents, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, Neural Stem Cells, Lipid droplet, Drug Discovery, Molecular Targeted Therapy, Enzyme Inhibitors, Cerebral Cortex, Neurons, 0303 health sciences, Dopaminergic, Parkinson Disease, Toxicity, alpha-Synuclein, Stearoyl-CoA Desaturase, Induced Pluripotent Stem Cells, Mice, Transgenic, Saccharomyces cerevisiae, Biology, Article, Cell Line, Diglycerides, 03 medical and health sciences, medicine, Animals, Humans, Metabolomics, Caenorhabditis elegans, Molecular Biology, Unsaturated fatty acid, Triglycerides, 030304 developmental biology, Alpha-synuclein, Dopaminergic Neurons, Neurotoxicity, Cell Biology, Lipid Droplets, medicine.disease, Lipid Metabolism, Mice, Inbred C57BL, Disease Models, Animal, chemistry, Nerve Degeneration, 030217 neurology & neurosurgery, Homeostasis, Oleic Acid

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995be04b05c6e841478eda306d3ad6bc
https://hdl.handle.net/1721.1/125128

المؤلفون: Gabriela Caraveo, Martin Soste, Susan Lindquist, Valeriya Baru, Valentina Cappelleti, Saranna Fanning, Luke Whitesell, Chee Yeun Chung, Paola Picotti, Yanmei Huang, Damian B. van Rossum, Sofia Zaichick

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 114 (52)

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Proteome, Calcineurin, FKBP12, α -synuclein, Parkinson’s Disease, Tacrolimus, Phosphatase, Tacrolimus Binding Protein 1A, Pharmacology, Dephosphorylation, Rats, Sprague-Dawley, 03 medical and health sciences, α-synuclein, medicine, Animals, Multidisciplinary, Chemistry, Parkinson Disease, Biological Sciences, medicine.disease, Phosphoproteins, 3. Good health, Rats, Disease Models, Animal, 030104 developmental biology, FKBP, PNAS Plus, Toxicity, alpha-Synuclein, α synuclein, Neuroscience

وصف الملف: application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736b1a33474e7145c686992fe722e441
https://pubmed.ncbi.nlm.nih.gov/29229832

المؤلفون: Pavan K. Auluck, Hanna Kim, Xiaohui Yan, Gabriela Caraveo, Kim A. Caldwell, Martin Soste, Paola Picotti, Chee Yeun Chung, Valeriya Baru, Luke Whitesell, Eugene V. Mosharov, David T. Yue, Manu Ben-Johny, Guy A. Caldwell, David Sulzer, Susan Lindquist

المصدر: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Lewy Body Disease, Saccharomyces cerevisiae Proteins, Calcineurin Inhibitors, Models, Neurological, Phosphatase, Mice, Transgenic, Saccharomyces cerevisiae, Biology, Tacrolimus, Mice, chemistry.chemical_compound, Calmodulin, Animals, Humans, Calcium Signaling, Cells, Cultured, Neuroinflammation, Calcium signaling, Neurons, Alpha-synuclein, Synucleinopathies, Multidisciplinary, NFATC Transcription Factors, Calcineurin, Parkinson Disease, NFAT, Phosphoric Monoester Hydrolases, Recombinant Proteins, Rats, 3. Good health, PNAS Plus, chemistry, Biochemistry, Gene Knockdown Techniques, alpha-Synuclein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46c8de704119b87b68c5f978fff703a