المؤلفون: Vieira de Sá R; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Sudria-Lopez E; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Cañizares Luna M; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Harschnitz O; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands.; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CX, Utrecht, The Netherlands.; Human Technopole, Viale Rita Levi-Montalcini, 1, 20157, Milan, Italy., van den Heuvel DMA; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Kling S; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Vonk D; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Westeneng HJ; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CX, Utrecht, The Netherlands., Karst H; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Bloemenkamp L; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Varderidou-Minasian S; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Schlegel DK; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Mars M; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Broekhoven MH; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., van Kronenburg NCH; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Adolfs Y; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Vangoor VR; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., de Jongh R; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Ljubikj T; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Peeters L; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Seeler S; Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Mocholi E; Center for Molecuar Medicine, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Basak O; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Gordon D; Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK., Giuliani F; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CX, Utrecht, The Netherlands., Verhoeff T; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Korsten G; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Calafat Pla T; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Venø MT; Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Omiics ApS, Aarhus, Denmark., Kjems J; Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Talbot K; Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK., van Es MA; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CX, Utrecht, The Netherlands., Veldink JH; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CX, Utrecht, The Netherlands., van den Berg LH; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CX, Utrecht, The Netherlands., Zelina P; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Pasterkamp RJ; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands. r.j.pasterkamp@umcutrecht.nl.

المصدر: Nature communications [Nat Commun] 2024 Aug 29; Vol. 15 (1), pp. 7484. Date of Electronic Publication: 2024 Aug 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis*/genetics , Amyotrophic Lateral Sclerosis*/metabolism , Amyotrophic Lateral Sclerosis*/pathology , Ataxin-2*/genetics , Ataxin-2*/metabolism , Peptides*/metabolism , Peptides*/genetics , Induced Pluripotent Stem Cells*/metabolism , Motor Neurons*/metabolism , Motor Neurons*/pathology , Disease Models, Animal* , Mice, Transgenic*, Humans ; Animals ; Mice ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Phenotype ; Male ; Female ; Mitochondria/metabolism ; Neurites/metabolism

المؤلفون: Rybiczka-Tešulov M; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Institute of Medical Genetics, Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria., Garritsen O; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Venø MT; Department of Molecular Biology and Genetics, Interdisciplinary Nanoscience Centre, Aarhus University, Aarhus C, Denmark.; Omiics ApS, Aarhus N, Denmark., Wieg L; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Dijk RV; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; VectorY Therapeutics, Matrix Innovation Center VI, Amsterdam, The Netherlands., Rahimi K; Department of Molecular Biology and Genetics, Interdisciplinary Nanoscience Centre, Aarhus University, Aarhus C, Denmark.; Department of Genetics, Blavatnik Institute, Harvard Medical School, MA, Boston, USA., Gomes-Duarte A; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; VectorY Therapeutics, Matrix Innovation Center VI, Amsterdam, The Netherlands., Wit M; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van de Haar LL; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Berlin Institute for Medical Systems Biology, Max Delbrück Center, Berlin, Germany., Michels L; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; VectorY Therapeutics, Matrix Innovation Center VI, Amsterdam, The Netherlands., van Kronenburg NCH; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van der Meer C; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Kjems J; Department of Molecular Biology and Genetics, Interdisciplinary Nanoscience Centre, Aarhus University, Aarhus C, Denmark., Vangoor VR; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Pasterkamp RJ; Department of Translational Neuroscience, UMC Utrecht Brain Center Utrecht, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. r.j.pasterkamp@umcutrecht.nl.

المصدر: Nature communications [Nat Commun] 2024 Aug 08; Vol. 15 (1), pp. 6773. Date of Electronic Publication: 2024 Aug 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: RNA, Circular*/genetics , RNA, Circular*/metabolism , Dopaminergic Neurons*/metabolism , Dopaminergic Neurons*/cytology , Mesencephalon*/metabolism , Mesencephalon*/cytology , Mesencephalon*/embryology , Cell Movement*/genetics , Gene Expression Regulation, Developmental*, Animals ; Mice ; Neurogenesis/genetics ; Female ; Alternative Splicing ; Mice, Inbred C57BL ; Transcriptome

المؤلفون: Gomes-Duarte A; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Venø MT; Interdisciplinary Nanoscience Center, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Omiics ApS, Aarhus, Denmark., de Wit M; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Senthilkumar K; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Broekhoven MH; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., van den Herik J; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Heeres FR; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., van Rossum D; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Rybiczka-Tesulov M; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Legnini I; Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., van Rijen PC; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., van Eijsden P; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Gosselaar PH; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Rajewsky N; Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Kjems J; Interdisciplinary Nanoscience Center, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Vangoor VR; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Pasterkamp RJ; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

المصدر: Frontiers in molecular neuroscience [Front Mol Neurosci] 2022 Mar 03; Vol. 15, pp. 832133. Date of Electronic Publication: 2022 Mar 03 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: PubMed not MEDLINE

المؤلفون: Reschke CR; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Silva LFA; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Vangoor VR; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, the Netherlands., Rosso M; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., David B; Department of Epileptology, University Hospital Bonn, 53127 Bonn, Germany., Cavanagh BL; Cellular and Molecular Imaging Core, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Connolly NMC; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Brennan GP; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Sanz-Rodriguez A; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Mooney C; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; School of Computer Science, University College Dublin, Dublin 4, Ireland., Batool A; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Greene C; Department of Genetics, Trinity College Dublin, Dublin 2, Ireland., Brennan M; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Conroy RM; Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Rüber T; Department of Epileptology, University Hospital Bonn, 53127 Bonn, Germany; Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, Goethe University Frankfurt, 60528 Frankfurt am Main, Germany; Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, 60528 Frankfurt am Main, Germany., Prehn JHM; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., Campbell M; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; Department of Genetics, Trinity College Dublin, Dublin 2, Ireland., Pasterkamp RJ; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, the Netherlands., Henshall DC; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland; FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland. Electronic address: dhenshall@rcsi.ie.

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Jun 02; Vol. 29 (6), pp. 2041-2052. Date of Electronic Publication: 2021 Feb 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antagomirs/*genetics , Blood-Brain Barrier/*metabolism , Epilepsy/*genetics , Epilepsy/*therapy, Animals ; Antagomirs/administration & dosage ; Blood-Brain Barrier/pathology ; Disease Management ; Disease Models, Animal ; Disease Susceptibility ; Gene Expression Regulation ; Gene Silencing ; Gene Transfer Techniques ; Genetic Predisposition to Disease ; Genetic Therapy ; Mice ; MicroRNAs/genetics ; RNA Interference ; Treatment Outcome

المؤلفون: Vangoor VR; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Gomes-Duarte A; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Pasterkamp RJ; Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands.

المصدر: Journal of neurochemistry [J Neurochem] 2021 Mar; Vol. 156 (6), pp. 777-801. Date of Electronic Publication: 2020 Oct 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

مواضيع طبية MeSH: Motor Neuron Disease/*genetics , Motor Neurons/*physiology , RNA, Long Noncoding/*genetics , RNA, Long Noncoding/*physiology, Animals ; Humans ; Motor Neuron Disease/physiopathology

المؤلفون: Gomes-Duarte A; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Bauer S; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe-University Frankfurt, Frankfurt, Germany.; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg, Germany., Venø MT; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Omiics ApS, Aarhus, Denmark., Norwood BA; Department of Neuroscience, Expesicor Inc., Kalispell, MT, United States.; Diagnostics Development, FYR Diagnostics, Missoula, MT, United States., Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, Ireland., Kjems J; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Rosenow F; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe-University Frankfurt, Frankfurt, Germany.; Epilepsy Center, Department of Neurology, Philipps University Marburg, Marburg, Germany., Vangoor VR; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands., Pasterkamp RJ; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

المصدر: Frontiers in genetics [Front Genet] 2021 Jan 28; Vol. 12, pp. 627907. Date of Electronic Publication: 2021 Jan 28 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101560621 Publication Model: eCollection Cited Medium: Print ISSN: 1664-8021 (Print) Linking ISSN: 16648021 NLM ISO Abbreviation: Front Genet Subsets: PubMed not MEDLINE

المؤلفون: Venø MT; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Reschke CR; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Morris G; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Connolly NMC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Su J; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Yan Y; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Engel T; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Jimenez-Mateos EM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Harder LM; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Pultz D; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Haunsberger SJ; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Pal A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Heller JP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Campbell A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Langa E; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Brennan GP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Conboy K; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Richardson A; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom., Norwood BA; Department of Neuroscience, Expesicor Inc, Kalispell, MT 59901.; Diagnostics Development, FYR Diagnostics, Missoula, MT 59801., Costard LS; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Neubert V; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Rostock, 18051, Germany., Del Gallo F; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Salvetti B; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Vangoor VR; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Sanz-Rodriguez A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Muilu J; Research and Development, BC Platforms, FI-02130, Espoo, Finland., Fabene PF; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 8 - 37134, Verona, Italy., Pasterkamp RJ; Affiliated Partner of the European Reference Network EpiCARE, Department of Translational Neuroscience, University Medical Center Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG, Utrecht, The Netherlands., Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland., Schorge S; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.; UCL School of Pharmacy, University College London, London, WC1N 1AX, United Kingdom., Andersen JS; Center for Experimental Bioinformatics, University of Southern Denmark, DK-5230 Odense M, Denmark., Rosenow F; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Bauer S; Epilepsy Center, Department of Neurology, Philipps University Marburg, 35043, Marburg, Germany.; Epilepsy Center Frankfurt Rhine-Main, Neurocenter, University Hospital Frankfurt and Center for Personalized Translational Epilepsy Research, Goethe University Frankfurt, 60528, Frankfurt, Germany., Kjems J; Interdisciplinary Nanoscience Centre, Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark., Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland; dhenshall@rcsi.ie.; FutureNeuro, The Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, D02 YN77, Ireland.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 07; Vol. 117 (27), pp. 15977-15988. Date of Electronic Publication: 2020 Jun 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Epilepsy, Temporal Lobe/*drug therapy , Epilepsy, Temporal Lobe/*metabolism , MicroRNAs/*drug effects , MicroRNAs/*metabolism , Oligonucleotides, Antisense/*pharmacology , Seizures/*drug therapy , Seizures/*metabolism, Animals ; Antagomirs/pharmacology ; Argonaute Proteins/genetics ; Argonaute Proteins/metabolism ; Biomarkers ; Disease Models, Animal ; Epilepsy ; Female ; Hippocampus/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Proteomics ; Rats ; Rats, Sprague-Dawley ; Seizures/genetics ; Systems Analysis ; Up-Regulation/drug effects

المؤلفون: Vangoor VR; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Reschke CR; Department of Physiology and Medical Physics.; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin D02, Ireland., Senthilkumar K; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., van de Haar LL; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., de Wit M; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Giuliani G; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Broekhoven MH; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Morris G; Department of Physiology and Medical Physics.; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin D02, Ireland.; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London WC1N 3BG, United Kingdom., Engel T; Department of Physiology and Medical Physics., Brennan GP; Department of Physiology and Medical Physics.; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin D02, Ireland., Conroy RM; Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland., van Rijen PC; Department of Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, 3584 CG, Utrecht, The Netherlands, and., Gosselaar PH; Department of Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, 3584 CG, Utrecht, The Netherlands, and., Schorge S; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London WC1N 3BG, United Kingdom., Schaapveld RQJ; InteRNA Technologies 3584 CM Utrecht, The Netherlands., Henshall DC; Department of Physiology and Medical Physics.; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin D02, Ireland., De Graan PNE; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Pasterkamp RJ; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands, r.j.pasterkamp@umcutrecht.nl.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2019 Jun 26; Vol. 39 (26), pp. 5064-5079. Date of Electronic Publication: 2019 Apr 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Antagomirs/*therapeutic use , Epilepsy, Temporal Lobe/*drug therapy , Hippocampus/*drug effects , MicroRNAs/*antagonists & inhibitors , Seizures/*drug therapy, Animals ; Antagomirs/pharmacology ; Disease Models, Animal ; Epilepsy, Temporal Lobe/genetics ; Epilepsy, Temporal Lobe/metabolism ; Hippocampus/metabolism ; MEF2 Transcription Factors/genetics ; MEF2 Transcription Factors/metabolism ; Male ; Mice ; Neurons/drug effects ; Neurons/metabolism ; Seizures/genetics ; Seizures/metabolism ; Treatment Outcome

المؤلفون: Shi Y; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Lin S; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Staats KA; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Li Y; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Chang WH; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Hung ST; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Hendricks E; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Linares GR; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Wang Y; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.; Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Son EY; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA., Wen X; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Kisler K; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.; Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Wilkinson B; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Menendez L; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Sugawara T; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Woolwine P; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Huang M; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Cowan MJ; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Ge B; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Koutsodendris N; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Sandor KP; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Komberg J; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Vangoor VR; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Senthilkumar K; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Hennes V; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Seah C; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA., Nelson AR; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.; Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Cheng TY; DRVision Technologies, LLC, Bellvue, Washington, USA., Lee SJ; DRVision Technologies, LLC, Bellvue, Washington, USA., August PR; Icagen Corporation, Oro Valley, Arizona, USA., Chen JA; Verge Genomics, San Francisco, California, USA., Wisniewski N; Verge Genomics, San Francisco, California, USA., Hanson-Smith V; Verge Genomics, San Francisco, California, USA., Belgard TG; Verge Genomics, San Francisco, California, USA., Zhang A; Verge Genomics, San Francisco, California, USA., Coba M; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.; Department of Psychiatry and Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Grunseich C; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA., Ward ME; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA., van den Berg LH; Department of Neurology, University Medical Center Utrecht, Utrecht, the Netherlands., Pasterkamp RJ; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Trotti D; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Zlokovic BV; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.; Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Ichida JK; Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, California, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

المصدر: Nature medicine [Nat Med] 2018 Mar; Vol. 24 (3), pp. 313-325. Date of Electronic Publication: 2018 Feb 05.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*genetics , C9orf72 Protein/*genetics , Frontotemporal Dementia/*genetics , Nerve Degeneration/*genetics , rab5 GTP-Binding Proteins/*genetics, Amyotrophic Lateral Sclerosis/pathology ; Animals ; DNA Repeat Expansion/genetics ; Disease Models, Animal ; Endosomes/genetics ; Frontotemporal Dementia/pathology ; Gene Expression Regulation/genetics ; Haploinsufficiency/genetics ; Humans ; Introns/genetics ; Motor Neurons/metabolism ; Motor Neurons/pathology ; Mutation ; Nerve Degeneration/physiopathology

SCR Disease Name: Frontotemporal Dementia With Motor Neuron Disease

المؤلفون: van Battum EY; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Verhagen MG; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Vangoor VR; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Fujita Y; Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan., Derijck AAHA; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., O'Duibhir E; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Giuliani G; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., de Gunst T; InteRNA Technologies B.V., Yalelaan 62, 3584 CM Utrecht, The Netherlands, and., Adolfs Y; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands., Lelieveld D; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands., Egan D; Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands., Schaapveld RQJ; InteRNA Technologies B.V., Yalelaan 62, 3584 CM Utrecht, The Netherlands, and., Yamashita T; Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan., Pasterkamp RJ; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands, r.j.pasterkamp@umcutrecht.nl.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2018 Jan 17; Vol. 38 (3), pp. 613-630. Date of Electronic Publication: 2017 Dec 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation/*physiology , Kruppel-Like Transcription Factors/*metabolism , MicroRNAs/*metabolism , Nerve Regeneration/*physiology, Animals ; Axons/metabolism ; Female ; Humans ; Kruppel-Like Factor 4 ; Male ; Mice ; Mice, Inbred C57BL ; Retinal Ganglion Cells/physiology