المؤلفون: Sarma S; Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, United States of America., Hodzic-Santor B; Division of General Internal Medicine, Sinai Health System, Toronto, Ontario, Canada., Raissi A; Division of General Internal Medicine, Sinai Health System, Toronto, Ontario, Canada., Colacci M; Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Verma AA; Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of General Internal Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Razak F; Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of General Internal Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Højbjerg Lassen MC; Department of Cardiology, Gentofte University Hospital, University of Copenhagen, Copenhagen, Denmark., Fralick M; Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada; Division of General Internal Medicine, Sinai Health System, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address: mike.fralick@utoronto.ca.

المصدر: Journal of diabetes and its complications [J Diabetes Complications] 2024 Sep; Vol. 38 (9), pp. 108827. Date of Electronic Publication: 2024 Jul 29.

نوع المنشور: Journal Article; Multicenter Study

بيانات الدورية: Publisher: Elsevier Science Pub. Co Country of Publication: United States NLM ID: 9204583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-460X (Electronic) Linking ISSN: 10568727 NLM ISO Abbreviation: J Diabetes Complications Subsets: MEDLINE

مواضيع طبية MeSH: Diabetic Ketoacidosis*/epidemiology , Diabetic Ketoacidosis*/chemically induced , Sodium-Glucose Transporter 2 Inhibitors*/therapeutic use , Sodium-Glucose Transporter 2 Inhibitors*/adverse effects , Hospitalization*/statistics & numerical data , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/blood , Diabetes Mellitus, Type 2*/epidemiology, Humans ; Male ; Female ; Middle Aged ; Cohort Studies ; Aged ; Adult ; Dipeptidyl-Peptidase IV Inhibitors/therapeutic use ; Dipeptidyl-Peptidase IV Inhibitors/adverse effects ; Risk Factors ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/therapeutic use

المؤلفون: Malecki SL; Department of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address: sarah.voll@mail.utoronto.ca., Loffler A; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada., Tamming D; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada., Dyrby Johansen N; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Biering-Sørensen T; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Fralick M; Division of General Internal Medicine, Sinai Health System, ON, Toronto, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada., Sohail S; Department of Medicine, University of Toronto, Toronto, ON, Canada., Shi J; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada., Roberts SB; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada., Colacci M; Department of Medicine, University of Toronto, Toronto, ON, Canada; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada., Ismail M; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada., Razak F; Department of Medicine, University of Toronto, Toronto, ON, Canada; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada., Verma AA; Department of Medicine, University of Toronto, Toronto, ON, Canada; St. Michael's Hospital, University of Toronto, Toronto, ON, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

المصدر: International journal of medical informatics [Int J Med Inform] 2024 Sep; Vol. 189, pp. 105508. Date of Electronic Publication: 2024 May 29.

نوع المنشور: Journal Article; Validation Study

بيانات الدورية: Publisher: Elsevier Science Ireland Ltd Country of Publication: Ireland NLM ID: 9711057 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8243 (Electronic) Linking ISSN: 13865056 NLM ISO Abbreviation: Int J Med Inform Subsets: MEDLINE

مواضيع طبية MeSH: International Classification of Diseases* , Algorithms*, Humans ; Canada ; Denmark ; Software ; Hospitalization/statistics & numerical data

المؤلفون: Bai AD; Division of Infectious Diseases, Department of Medicine, Queen's University, Kingston, Ontario, Canada., Srivastava S; Division of General Internal Medicine, Department of Medicine, Queen's University, Kingston, Ontario, Canada., Leung M; Division of General Internal Medicine, Department of Medicine, Queen's University, Kingston, Ontario, Canada., Johnson H; Division of General Internal Medicine, Department of Medicine, Queen's University, Kingston, Ontario, Canada., Verma AA; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada., Razak F; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

المصدر: JPEN. Journal of parenteral and enteral nutrition [JPEN J Parenter Enteral Nutr] 2024 Aug 20. Date of Electronic Publication: 2024 Aug 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 7804134 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-2444 (Electronic) Linking ISSN: 01486071 NLM ISO Abbreviation: JPEN J Parenter Enteral Nutr Subsets: MEDLINE

المؤلفون: Bai AD; Division of Infectious Diseases, Department of Medicine, Queen's University, Kingston, ON, Canada., Srivastava S; Division of General Internal Medicine, Department of Medicine, Queen's University, Kingston, ON, Canada., Martinez Cajas JL; Division of Infectious Diseases, Department of Medicine, Queen's University, Kingston, ON, Canada., Razak F; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada., Verma AA; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

المصدر: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Jul 27. Date of Electronic Publication: 2024 Jul 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE

المؤلفون: Bai AD; Division of Infectious Diseases, Department of Medicine, Queen's University, Kingston, ON, Canada. Electronic address: tony.bai@queensu.ca., Srivastava S; Division of General Internal Medicine, Department of Medicine, Queen's University, Kingston, ON, Canada., Digby GC; Division of Respirology, Department of Medicine, Queen's University, Kingston, ON, Canada., Girard V; Internal Medicine Residency Program, Department of Medicine, Queen's University, Kingston, ON, Canada., Razak F; Department of Medicine, University of Toronto, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada., Verma AA; Department of Medicine, University of Toronto, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.

المصدر: Chest [Chest] 2024 Jul; Vol. 166 (1), pp. 39-48. Date of Electronic Publication: 2024 Feb 20.

نوع المنشور: Journal Article; Multicenter Study

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0231335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-3543 (Electronic) Linking ISSN: 00123692 NLM ISO Abbreviation: Chest Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/therapeutic use , Hospital Mortality* , Pneumonia, Aspiration*/drug therapy , Pneumonia, Aspiration*/epidemiology, Humans ; Male ; Retrospective Studies ; Female ; Aged ; Ontario/epidemiology ; Middle Aged ; Aged, 80 and over ; Community-Acquired Infections/drug therapy ; Clostridium Infections/drug therapy ; Clostridium Infections/epidemiology ; Bacteria, Anaerobic/drug effects ; Clostridioides difficile

المؤلفون: Cressman AM; Temerty Faculty of Medicine, University of Toronto, Toronto, Toronto, Ontario, Canada.; Division of General Internal Medicine, University of Toronto, Toronto, Ontario, Canada., Wen B; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada., Saha S; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada., Jun HY; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada., Waters R; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada., Lail S; Unity Health Toronto, Toronto, Ontario, Canada.; Department of Family and Community Medicine, Temerty Faculty of Medicine, Toronto, Canada., Jabeen A; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada., Koppula R; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada., Lapointe-Shaw L; Temerty Faculty of Medicine, University of Toronto, Toronto, Toronto, Ontario, Canada.; Division of General Internal Medicine, University of Toronto, Toronto, Ontario, Canada., Sheehan KA; Temerty Faculty of Medicine, University of Toronto, Toronto, Toronto, Ontario, Canada.; Division of Psychiatry, The University of Toronto, Toronto, Ontario, Canada., Weinerman A; Temerty Faculty of Medicine, University of Toronto, Toronto, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada., Daneman N; Temerty Faculty of Medicine, University of Toronto, Toronto, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada., Verma AA; Temerty Faculty of Medicine, University of Toronto, Toronto, Toronto, Ontario, Canada.; Division of General Internal Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada.; Unity Health Toronto, Toronto, Ontario, Canada., Razak F; Temerty Faculty of Medicine, University of Toronto, Toronto, Toronto, Ontario, Canada.; Division of General Internal Medicine, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada.; Unity Health Toronto, Toronto, Ontario, Canada., MacFadden D; The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

المصدر: PloS one [PLoS One] 2024 Jun 26; Vol. 19 (6), pp. e0299473. Date of Electronic Publication: 2024 Jun 26 (Print Publication: 2024).

نوع المنشور: Journal Article; Multicenter Study

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis*/mortality , Sepsis*/diagnosis , Electronic Health Records* , Hospital Mortality* , Severity of Illness Index*, Humans ; Male ; Aged ; Female ; Middle Aged ; Retrospective Studies ; Aged, 80 and over ; Length of Stay ; Intensive Care Units ; ROC Curve

المؤلفون: Malecki S; Internal Medicine Residency Program, University of Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada., Loffler A; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Liao F; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Hora T; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Agarwal A; Internal Medicine Residency Program, University of Toronto, Toronto, Ontario, Canada., Lail S; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Roberts SB; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., McFadden D; The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Gupta S; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada., Razak F; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Canada., Verma AA; Internal Medicine Residency Program, University of Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.

المصدر: Journal of hospital medicine [J Hosp Med] 2024 Jun 02. Date of Electronic Publication: 2024 Jun 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101271025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-5606 (Electronic) Linking ISSN: 15535592 NLM ISO Abbreviation: J Hosp Med Subsets: MEDLINE

المؤلفون: Hodzic-Santor B; Division of General Internal Medicine, Sinai Health System, Toronto, Ontario, Canada., Colacci M; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada., Raissi A; Division of General Internal Medicine, Sinai Health System, Toronto, Ontario, Canada., Ray P; Division of General Internal Medicine, Sinai Health System, Toronto, Ontario, Canada., Verma AA; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada; Division of General Internal Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Razak F; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada; Division of General Internal Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., MacFadden DR; The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Biering-Sørensen T; Department of Cardiology, Copenhagen University Hospital-Herlev & Gentofte, Copenhagen, Denmark., Skaarup KG; Department of Cardiology, Copenhagen University Hospital-Herlev & Gentofte, Copenhagen, Denmark., Sarma S; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States., Fralick M; Division of General Internal Medicine, Sinai Health System, Toronto, Ontario, Canada; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address: mike.fralick@mail.utoronto.ca.

المصدر: Canadian journal of diabetes [Can J Diabetes] 2024 Jun; Vol. 48 (4), pp. 227-232. Date of Electronic Publication: 2024 Jan 21.

نوع المنشور: Journal Article; Multicenter Study; Validation Study

بيانات الدورية: Publisher: Canadian Diabetes Association Country of Publication: Canada NLM ID: 101148810 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3840 (Electronic) Linking ISSN: 14992671 NLM ISO Abbreviation: Can J Diabetes Subsets: MEDLINE

مواضيع طبية MeSH: Diabetic Ketoacidosis*/diagnosis , Diabetic Ketoacidosis*/epidemiology , International Classification of Diseases*/standards, Humans ; Cross-Sectional Studies ; Female ; Male ; Adult ; Middle Aged ; Hospitalization/statistics & numerical data ; Ontario/epidemiology

المؤلفون: Sheehan KA; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Centre for Mental Health, University Health Network, Toronto, ON, Canada., Shin S; St. Michael's Hospital, Unity Health Network, Toronto, ON, Canada., Hall E; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Department of Psychiatry, Unity Health Network, Toronto, ON, Canada., Mak DYF; St. Michael's Hospital, Unity Health Network, Toronto, ON, Canada., Lapointe-Shaw L; Department of Medicine, University of Toronto, Toronto ON, Canada.; Department of Medicine, University Health Network, Toronto, ON, Canada., Tang T; Department of Medicine, University of Toronto, Toronto ON, Canada.; Institute for Better Health, Trillium Health Partners, Mississauga, ON, Canada., Marwaha S; Department of Medicine, University of Toronto, Toronto ON, Canada.; Department of Medicine, Unity Health Network, Toronto, ON, Canada., Gandell D; Department of Medicine, University of Toronto, Toronto ON, Canada.; Department of Medicine, Sunnybrook Heatlh Sciences Centre, Toronto, ON, Canada., Rawal S; Department of Medicine, University of Toronto, Toronto ON, Canada.; Department of Medicine, University Health Network, Toronto, ON, Canada., Inouye S; Aging Brain Center, Hebrew Senior Life, Boston, MA, United States of America.; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America., Verma AA; Department of Medicine, University of Toronto, Toronto ON, Canada.; Department of Medicine, Unity Health Network, Toronto, ON, Canada., Razak F; Department of Medicine, University of Toronto, Toronto ON, Canada.; Department of Medicine, Unity Health Network, Toronto, ON, Canada.

المصدر: PloS one [PLoS One] 2024 May 13; Vol. 19 (5), pp. e0302888. Date of Electronic Publication: 2024 May 13 (Print Publication: 2024).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Comparative Study

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Delirium*/diagnosis , Delirium*/epidemiology , International Classification of Diseases*, Humans ; Male ; Female ; Aged ; Retrospective Studies ; Middle Aged ; Aged, 80 and over ; Ontario/epidemiology ; Hospitalization ; Cohort Studies

المؤلفون: Malecki SL; Internal Medicine Residency Program, University of Toronto, Toronto, Ontario, Canada; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada., Heung T; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; The Dalglish Family 22q Clinic, University Health Network, Toronto, Ontario, Canada., Wodchis WP; Professor, Institute of Health Policy Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Senior Scientist and Research Chair, Implementation and Evaluation Science, Institute for Better Health, Trillium Health Partners, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada., Saskin R; ICES, Toronto, Ontario, Canada., Palma L; ICES, Toronto, Ontario, Canada., Verma AA; Li Ka Shing Knowledge Institute and Department of Medicine, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Bassett AS; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; The Dalglish Family 22q Clinic, University Health Network, Toronto, Ontario, Canada; Division of Cardiology, Centre for Mental Health & Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address: anne.bassett@utoronto.ca.

المصدر: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2024 May; Vol. 26 (5), pp. 101088. Date of Electronic Publication: 2024 Feb 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE

مواضيع طبية MeSH: Health Care Costs*, Humans ; Male ; Female ; Adult ; Young Adult ; Ontario/epidemiology ; Aged ; Adolescent ; Middle Aged ; DiGeorge Syndrome/genetics ; DiGeorge Syndrome/economics ; DiGeorge Syndrome/epidemiology ; Aging/genetics ; Case-Control Studies ; Chromosome Deletion ; Chromosomes, Human, Pair 22/genetics