المؤلفون: Mike A. Lyons, Barbara Graham, Ekaterina Maidj, Anne J. Lenaerts, Dashick W. L. Scott, Franceen Eshun-Wilson, Matt Zimmerman, Gregory T. Robertson, Michelle E. Ramey, Brendan K. Podell, Véronique Dartois, Firat Kaya, Bryce C. Asay, Courtney Hastings, Lisa M. Massoudi, Joshua Vasquez, Lisa K. Woolhiser, Veronica Gruppo, Claire L. Carter

المصدر: Antimicrobial Agents and Chemotherapy

مصطلحات موضوعية: Drug, Tuberculosis, C3HeB/FeJ, media_common.quotation_subject, Thiazines, murine models, Pharmacology, Piperazines, Mycobacterium tuberculosis, Mice, medicine, Animals, Distribution (pharmacology), Experimental Therapeutics, Pharmacology (medical), Pulmonary pathology, Mode of action, media_common, Mice, Inbred C3H, biology, business.industry, DprE1 inhibitors, biology.organism_classification, medicine.disease, Clinical trial, Infectious Diseases, tuberculosis, Pharmacodynamics, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e510dfb090f045f63f9ccd0aa795aebb
https://doi.org/10.1128/aac.00583-21

المؤلفون: Vincent Hernandez, Liang Liu, M. R. K. Alley, Iñigo Angulo-Barturen, Manisha Mohan, Baojie Wan, Andrés Palencia, Wai Choi, Zhenkun Ma, Lisa Feng, Scott G. Franzblau, Charles Z. Ding, Maliwan Meewan, David Barros, James C. Sacchettini, Joaquín Rullas, Paul Houston, Fernando Rock, Wei Bu, Anne J. Lenaerts, Tanya Parish, Alfonso Mendoza, Xianfeng Li, Lisa K. Woolhiser, Yasheen Zhou, M. Gerard Waters, Christopher B. Cooper, Jacob J. Plattner, Suoming Zhang, Eric E. Easom, Stephen Cusack, Veronica Gruppo, Theresa O’Malley, Holly Sexton, Esther Pérez-Herrán, Thomas R. Ioerger, Yuehong Wang

المصدر: Antimicrobial Agents and Chemotherapy
'Antimicrobial Agents and Chemotherapy ', vol: 60, pages: 6271-6280 (2016)

مصطلحات موضوعية: 0301 basic medicine, Drug, Tuberculosis, media_common.quotation_subject, 030106 microbiology, Mycobacterium smegmatis, Antitubercular Agents, Drug Evaluation, Preclinical, Administration, Oral, Mice, Inbred Strains, Microbial Sensitivity Tests, Pharmacology, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, medicine, Animals, Humans, Pharmacology (medical), Experimental Therapeutics, Vero Cells, media_common, Protein Synthesis Inhibitors, Mice, Inbred BALB C, Protein synthesis inhibitor, biology, Leucyl-tRNA synthetase, Isoniazid, biology.organism_classification, medicine.disease, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Infectious Diseases, chemistry, Streptomycin, Linezolid, Female, Leucine-tRNA Ligase, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ebfe2cf75e49febf18965798c8ef46
http://europepmc.org/articles/PMC5038265

المؤلفون: Pamela Berry, Yasheen Zhou, David S. Carter, Jason Halladay, Courtney Hastings, Vincent Hernandez, Bjorn Sunde, Weimin Mao, James C. Sacchettini, Aaron Korkegian, Wai Choi, Peter J. Tonge, Mrk Alley, Anne J. Lenaerts, Yi Xia, Gregory T. Robertson, Michael S. Scherman, Tanya Parish, Lisa K. Woolhiser, Veronica Gruppo, Lindsay Flint, Thomas R. Ioerger, Theresa O’Malley, Matthew B. McNeil

المصدر: Life Science Alliance

مصطلحات موضوعية: 0301 basic medicine, Drug, Tuberculosis, Health, Toxicology and Mutagenesis, media_common.quotation_subject, 030106 microbiology, Plant Science, Reductase, Biochemistry, Genetics and Molecular Biology (miscellaneous), Microbiology, Mycobacterium tuberculosis, 03 medical and health sciences, Medicine, Research Articles, media_common, chemistry.chemical_classification, Ecology, biology, business.industry, INHA, Isoniazid, medicine.disease, biology.organism_classification, In vitro, 3. Good health, 030104 developmental biology, Enzyme, chemistry, business, medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b771f3e73b484f275174c0822eeecdd9
http://europepmc.org/articles/PMC6238539

المؤلفون: Ashit Trivedi, Bernd Meibohm, David F. Bruhn, Michael R. McNeil, Marcus M. Maddox, Michael S. Scherman, Rakesh, Dora B. Madhura, Lei Yang, Robin B. Lee, Anne J. Lenaerts, Richard E. Lee, Janet C. Gilliland, Veronica Gruppo

المصدر: Bioorganic & Medicinal Chemistry. 20:6063-6072

مصطلحات موضوعية: Cell Survival, Nitrofurans, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Antitubercular Agents, Pharmaceutical Science, Microbial Sensitivity Tests, Biochemistry, Article, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Microsomes, Morpholine, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Solubility, Molecular Biology, Nitrofuran, Organic Chemistry, Isoxazoles, Mycobacterium tuberculosis, Rats, Bioavailability, chemistry, Molecular Medicine, Piperidine, Caco-2 Cells, Lead compound, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774b8ff1cb144c294974a0c3a34bb7c9
https://doi.org/10.1016/j.bmc.2012.08.023

المؤلفون: Anna E. Grzegorzewicz, Veronica Gruppo, Tamara Hess, Anne J. Lenaerts, Mary Jackson, Ha Pham, Michael S. Scherman, Vijay A. K.B. Gundi, Richard E. Lee, Victoria Jones, Sarah E. M. Born, Jana Korduláková, Christophe Morisseau, Michael R. McNeil, Elton J. North, Sivagami Sundaram Chavadi

المصدر: Nature chemical biology

مصطلحات موضوعية: Tuberculosis, Cell, Drug Evaluation, Preclinical, SQ109, Adamantane, Microbial Sensitivity Tests, Biology, Article, Microbiology, Mycolic acid, Small Molecule Libraries, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Drug Resistance, Bacterial, medicine, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, 030306 microbiology, Phenylurea Compounds, Cell Membrane, Membrane Transport Proteins, Trehalose, Biological Transport, Cell Biology, medicine.disease, biology.organism_classification, Anti-Bacterial Agents, 3. Good health, Membrane, medicine.anatomical_structure, Mycolic Acids, Biochemistry, chemistry, Mutation, Cord Factors, Mycobacterium species, Biogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660e2dae36ee7f45e081cc69d3f3e8c9
http://europepmc.org/articles/PMC3307863

المؤلفون: Anne J. Lenaerts, Janet C. Gilliland, Ian M. Orme, Mary Ann De Groote, Veronica Gruppo, Lisa K. Woolhiser

المصدر: Antimicrobial Agents and Chemotherapy. 56:731-738

مصطلحات موضوعية: Drug, Tuberculosis, media_common.quotation_subject, Antitubercular Agents, Microbial Sensitivity Tests, Pharmacology, Mycobacterium tuberculosis, Mice, In vivo, Isoniazid, Animals, Humans, Medicine, Experimental Therapeutics, Pharmacology (medical), Lung, Tuberculosis, Pulmonary, media_common, Mice, Inbred BALB C, biology, business.industry, Pyrazinamide, biology.organism_classification, medicine.disease, Clinical trial, Disease Models, Animal, Regimen, Treatment Outcome, Infectious Diseases, Immunology, Drug Therapy, Combination, Female, Rifampin, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535c71d850682115aa2fbf0f123052cc
https://doi.org/10.1128/aac.05701-11

المؤلفون: Veronica Gruppo, Gary K. Schoolnik, Martin I. Voskuil, M.R. Klein, Rowan P. Morris, Anne J. Lenaerts, Gavin J. Ryan, R.A. Morton, Kevin C. Visconti, Iona L. Bartek, R. Rutherford

المصدر: Tuberculosis. 89:310-316

مصطلحات موضوعية: Microbiology (medical), Tuberculosis, medicine.drug_class, Immunology, Antibiotics, Mutant, Virulence, Regulon, Microbiology, Article, Mycobacterium tuberculosis, Mice, Bacterial Proteins, Drug tolerance, Drug Resistance, Bacterial, medicine, Animals, Lung, Gene, Mice, Inbred BALB C, biology, Gene Expression Regulation, Bacterial, biology.organism_classification, medicine.disease, Anti-Bacterial Agents, DNA-Binding Proteins, Disease Models, Animal, Infectious Diseases, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e6e042a371f11376d9ff17b9e07374
https://doi.org/10.1016/j.tube.2009.06.001

المؤلفون: Tsungda Hsu, Randall J. Basaraba, Scott A. Fulton, W. Henry Boom, Ian M. Orme, William R. Jacobs, Gopinath S. Palanisamy, Oliver C. Turner, Scott M. Reba, Veronica Gruppo, Ana Paula Junqueira-Kipnis

المصدر: Immunology. 119:224-231

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Necrosis, Tuberculosis, medicine.medical_treatment, Immunology, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Microbiology, Mycobacterium tuberculosis, Pathogenesis, Interferon-gamma, Mice, Bacterial Proteins, Cell Movement, medicine, Animals, Immunology and Allergy, Cytotoxic T cell, Interferon gamma, Lung, Mice, Knockout, Mycobacterium bovis, Virulence, biology, Original Articles, Macrophage Activation, biology.organism_classification, medicine.disease, Mice, Inbred C57BL, Cytokine, Genes, Bacterial, Disease Progression, Female, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ca07adaf8b7f661c809ccae67c3479
https://doi.org/10.1111/j.1365-2567.2006.02427.x

المؤلفون: Robert C. Reynolds, Karen S. Marietta, Jerry D. Rose, Christine M. Johnson, Anne J. Lenaerts, Ian M. Orme, Nicholas M. Tompkins, Diane K. Driscoll, Veronica Gruppo

المصدر: Antimicrobial Agents and Chemotherapy. 49:2294-2301

مصطلحات موضوعية: Tuberculosis, Antitubercular Agents, Colony Count, Microbial, Drug Evaluation, Preclinical, SQ109, Microbial Sensitivity Tests, Pharmacology, Biology, Mycobacterium tuberculosis, Mice, chemistry.chemical_compound, In vivo, Moxifloxacin, Tuberculosis, Multidrug-Resistant, medicine, Animals, Humans, Experimental Therapeutics, Pharmacology (medical), Lung, Tuberculosis, Pulmonary, Isoniazid, medicine.disease, biology.organism_classification, Gatifloxacin, Specific Pathogen-Free Organisms, Mice, Inbred C57BL, Disease Models, Animal, Metronidazole, Infectious Diseases, chemistry, Nitroimidazoles, Female, Spleen, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0acbf67ddfd632a7a610cd04ae1809
https://doi.org/10.1128/aac.49.6.2294-2301.2005

المؤلفون: Buka Samten, Peter F. Barnes, Homayoun Shams, Hassan Safi, André Kipnis, Shiping Wu, Susan T. Howard, Veronica Gruppo, David L. Lakey, Randall J. Basaraba, Ian M. Orme, Benjamin Wizel

المصدر: Molecular Microbiology. 51:1551-1562

مصطلحات موضوعية: Tuberculosis, Growth factor, medicine.medical_treatment, Virulence, chemical and pharmacologic phenomena, Biology, biology.organism_classification, medicine.disease, digestive system, Microbiology, law.invention, Mycobacterium tuberculosis, fluids and secretions, stomatognathic system, Sigma factor, law, Sense (molecular biology), medicine, Recombinant DNA, Molecular Biology, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf447731fdfa96c20cd03e644aefcc28
https://doi.org/10.1111/j.1365-2958.2003.03922.x