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1دورية أكاديمية
المؤلفون: Aashish Manglik, Henry Lin, Dipendra K. Aryal, John D. McCorvy, Daniela Dengler, Gregory Corder, Anat Levit, Ralf C. Kling, Viachaslau Bernat, Harald Hübner, Xi-Ping Huang, Maria F. Sassano
المصدر: Nature, Nature. 537(7619):185-190
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2
المؤلفون: Zi-Fu, Wang, Andrei, Ursu, Jessica L, Childs-Disney, Rea, Guertler, Wang-Yong, Yang, Viachaslau, Bernat, Suzanne G, Rzuczek, Rita, Fuerst, Yong-Jie, Zhang, Tania F, Gendron, Ilyas, Yildirim, Brendan G, Dwyer, Joseph E, Rice, Leonard, Petrucelli, Matthew D, Disney
المصدر: Cell chemical biology. 26(2)
مصطلحات موضوعية: Binding Sites, DNA Repeat Expansion, C9orf72 Protein, Amyotrophic Lateral Sclerosis, RNA-Binding Proteins, Molecular Dynamics Simulation, Article, Small Molecule Libraries, Kinetics, Frontotemporal Dementia, Polyribosomes, Protein Biosynthesis, Humans, Nucleic Acid Conformation, Thermodynamics, Nuclear Magnetic Resonance, Biomolecular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::db489aeede88b88763d3b52015dafa54
https://pubmed.ncbi.nlm.nih.gov/30503283 -
3
المصدر: ChemMedChem. 10:566-574
مصطلحات موضوعية: Receptors, CXCR3, Allosteric modulator, Arrestins, Stereochemistry, Allosteric regulation, Biology, Ligands, CXCR3, Biochemistry, Allosteric Regulation, Drug Discovery, Functional selectivity, Humans, Immunologic Factors, CXCL11, General Pharmacology, Toxicology and Pharmaceutics, Receptor, beta-Arrestins, Quinazolinones, G protein-coupled receptor, Pharmacology, Aza Compounds, Organic Chemistry, Ligand (biochemistry), Chemokine CXCL11, HEK293 Cells, Biophysics, Molecular Medicine, Signal Transduction
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4Identifying Modulators of CXC Receptors 3 and 4 with Tailored Selectivity Using Multi-Target Docking
المؤلفون: Regine Brox, Denis Schmidt, Peter Kolb, Nuska Tschammer, Viachaslau Bernat
المصدر: ACS Chemical Biology. 10:715-724
مصطلحات موضوعية: Receptors, CXCR4, Receptors, CXCR3, Computational biology, Pharmacology, Biology, Ligands, Sulfur Radioisotopes, CXCR3, Biochemistry, Molecular Docking Simulation, Protein Structure, Secondary, Small Molecule Libraries, Structure-Activity Relationship, Chemokine receptor, Drug Discovery, Humans, Homology modeling, Binding site, Receptor, Binding Sites, Drug discovery, Cell Membrane, General Medicine, Protein Structure, Tertiary, HEK293 Cells, Guanosine 5'-O-(3-Thiotriphosphate), Structural Homology, Protein, Docking (molecular), Molecular Medicine, Databases, Chemical, Protein Binding
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5
المؤلفون: Nuska Tschammer, Viachaslau Bernat, Frank W. Heinemann, Tizita Haimanot Admas, Regine Brox
المصدر: ACS Chemical Biology. 9:2664-2677
مصطلحات موضوعية: inorganic chemicals, chemistry.chemical_classification, Receptors, CXCR3, Chemistry, Stereochemistry, Biomolecule, Allosteric regulation, General Medicine, CXCR3, Boronic Acids, Biochemistry, chemistry.chemical_compound, Allosteric Regulation, Docking (molecular), Covalent bond, Molecular Probes, Molecular Medicine, Moiety, Homology modeling, Boronic acid
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6
المؤلفون: Tania F. Gendron, Brendan G. Dwyer, Joseph E. Rice, Rea Guertler, Rita Fuerst, Matthew D. Disney, Wang Yong Yang, Yong Jie Zhang, Viachaslau Bernat, Leonard Petrucelli, Andrei Ursu, Zi-Fu Wang, Ilyas Yildirim, Jessica L. Childs-Disney, Suzanne G. Rzuczek
المصدر: Cell Chemical Biology. 26:179-190.e12
مصطلحات موضوعية: Pharmacology, 010405 organic chemistry, Clinical Biochemistry, RNA, Translation (biology), Nuclear magnetic resonance spectroscopy, Biology, 01 natural sciences, Biochemistry, Small molecule, Molecular biology, 0104 chemical sciences, C9orf72, Drug Discovery, Ran, Nucleic acid, Molecular Medicine, Trinucleotide repeat expansion, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ef0b11fe13bb972db023d5e9b322d441
https://doi.org/10.1016/j.chembiol.2018.10.018 -
7
المصدر: ChemMedChem. 11(6)
مصطلحات موضوعية: 0301 basic medicine, Receptors, CXCR3, Stereochemistry, Allosteric regulation, Photoaffinity Labels, Pyrimidinones, Tritium, Biochemistry, Mass Spectrometry, 03 medical and health sciences, chemistry.chemical_compound, Piperidines, Drug Discovery, Acetamides, Radioligand, Cyclic AMP, Humans, General Pharmacology, Toxicology and Pharmaceutics, G protein-coupled receptor, Pharmacology, Trifluoromethyl, Photoactivatable probes, Photolysis, Photoaffinity labeling, Chemistry, Ligand, Organic Chemistry, Chemokine CXCL11, 030104 developmental biology, HEK293 Cells, Molecular Medicine
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8
المؤلفون: Peter Gmeiner, Brian K. Kobilka, Viachaslau Bernat, Henry Lin, Dipendra K. Aryal, Da Duan, Gregory Corder, Brian K. Shoichet, Aashish Manglik, Ralf C. Kling, Anat Levit, Bryan L. Roth, Maria F. Sassano, Xi Ping Huang, Stefan Löber, Harald Hübner, John D. McCorvy, Grégory Scherrer, Daniela Dengler, Patrick M. Giguère
المصدر: Nature. 537(7619)
مصطلحات موضوعية: 0301 basic medicine, Male, Oliceridine, Receptors, Opioid, mu, Pain, Thiophenes, Pharmacology, GTP-Binding Protein alpha Subunits, Gi-Go, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Humans, Urea, Spiro Compounds, Receptor, G protein-coupled receptor, Mice, Knockout, Multidisciplinary, Drug discovery, business.industry, Alkaloid, HEK 293 cells, Analgesics, Opioid, Mice, Inbred C57BL, Molecular Docking Simulation, 030104 developmental biology, HEK293 Cells, chemistry, Opioid, Receptors, Opioid, Morphine, Analgesia, business, medicine.drug
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9
المصدر: ChemMedChem. 7(8)
مصطلحات موضوعية: Allosteric modulator, Receptors, CXCR3, Stereochemistry, Allosteric regulation, Pyrimidinones, Ligands, Tritium, Biochemistry, Chemokine receptor, Structure-Activity Relationship, Allosteric Regulation, Drug Discovery, Acetamides, Radioligand, Humans, CXCL11, General Pharmacology, Toxicology and Pharmaceutics, G protein-coupled receptor, Pharmacology, Binding Sites, Chemistry, Organic Chemistry, Cooperative binding, Small molecule, Chemokine CXCL11, Kinetics, HEK293 Cells, Molecular Medicine, Protein Binding
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10
المؤلفون: Viachaslau Bernat, Matthew D. Disney
المصدر: Neuron. (1):28-46
مصطلحات موضوعية: RNA Folding, RNA, Untranslated, Neuroscience(all), Computational biology, Biology, RNA Biochemistry, Ribosome, Article, Protein biosynthesis, Humans, Myotonic Dystrophy, Molecular Targeted Therapy, RNA, Messenger, General Neuroscience, Amyotrophic Lateral Sclerosis, Rational design, RNA, Small molecule, Cell biology, Tauopathies, Structural biology, Fragile X Syndrome, Frontotemporal Dementia, Nervous System Diseases, Function (biology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fbbdbeca8cdbed7df2c332a3dc7705