المؤلفون: da Silva SEB; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil.; Federal University of Pernambuco, Keizo Asami Institute - iLIKA, Recife, PE, Brazil., da Silva Moura JA; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., Branco Júnior JF; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., de Moraes Gomes PAT; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., de Paula SKS; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., Viana DCF; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., de Freitas Ramalho EAV; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., de Melo Gomes JV; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., Pereira MC; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil.; Federal University of Pernambuco, Laboratory of Immunomodulation and New Therapeutic Approaches - LINAT, Recife, PE, Brazil., da Rocha Pitta MG; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., da Rocha Pitta I; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil., da Rocha Pitta MG; Federal University of Pernambuco, Laboratory of Design and Drug Synthesis - LPSF, Recife, PE, Brazil.

المصدر: Current topics in medicinal chemistry [Curr Top Med Chem] 2024; Vol. 24 (14), pp. 1264-1277.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101119673 Publication Model: Print Cited Medium: Internet ISSN: 1873-4294 (Electronic) Linking ISSN: 15680266 NLM ISO Abbreviation: Curr Top Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Quinolines*/pharmacology , Quinolines*/chemistry , Quinolines*/chemical synthesis , Thiazolidinediones*/pharmacology , Thiazolidinediones*/chemical synthesis , Thiazolidinediones*/chemistry , Molecular Docking Simulation*, Molecular Structure ; Humans ; Cell Survival/drug effects ; Structure-Activity Relationship ; Animals ; PPAR gamma/agonists ; PPAR gamma/metabolism ; Dose-Response Relationship, Drug ; Mice ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Cyclooxygenase 2/metabolism ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/chemical synthesis ; Anti-Inflammatory Agents/chemistry ; Tumor Necrosis Factor-alpha/metabolism

المؤلفون: de Oliveira MCVA; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Viana DCF; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Silva AA; Laboratory of Experimental Neuropharmacology, Department of Physiology and Pharmacology, Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pereira MC; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Duarte FS; Laboratory of Experimental Neuropharmacology, Department of Physiology and Pharmacology, Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta MGR; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta IR; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta MGR; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil. Electronic address: marinagaldinopitta@gmail.com.

المصدر: Bioorganic chemistry [Bioorg Chem] 2022 Feb; Vol. 119, pp. 105548. Date of Electronic Publication: 2021 Dec 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anticonvulsants/*therapeutic use , Epilepsy/*drug therapy , Phthalimides/*therapeutic use , Seizures/*drug therapy , Thiazoles/*therapeutic use, Animals ; Anticonvulsants/chemical synthesis ; Anticonvulsants/chemistry ; Cells, Cultured ; Dose-Response Relationship, Drug ; Epilepsy/pathology ; Humans ; Male ; Molecular Docking Simulation ; Molecular Structure ; Phthalimides/chemical synthesis ; Phthalimides/chemistry ; Rats ; Rats, Wistar ; Seizures/pathology ; Structure-Activity Relationship ; Thiazoles/chemical synthesis ; Thiazoles/chemistry

المؤلفون: Ramalho EAVF; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Viana DCF; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Mendonça da Costa VC; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta M; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Rêgo MJBM; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta IDR; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil.; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta MGDR; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil.

المصدر: Medicinal chemistry (Shariqah (United Arab Emirates)) [Med Chem] 2022; Vol. 18 (9), pp. 980-989.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101240303 Publication Model: Print Cited Medium: Internet ISSN: 1875-6638 (Electronic) Linking ISSN: 15734064 NLM ISO Abbreviation: Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Oxindoles*, Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Almeida ML; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Viana DCF; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., da Costa VCM; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Dos Santos FA; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pereira MC; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta MGR; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., de Melo Rêgo MJB; Laboratory of Immunomodulation and New Therapeutic Approaches (LINAT), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta IR; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil., Pitta MGR; Laboratory of Design and Drug Synthesis (LPSF), Nucleus of Research in Therapeutical Innovation Suely Galdino (NUPIT SG), Biosciences Center, Federal University of Pernambuco, Recife, Brazil.

المصدر: Combinatorial chemistry & high throughput screening [Comb Chem High Throughput Screen] 2020; Vol. 23 (5), pp. 359-368.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9810948 Publication Model: Print Cited Medium: Internet ISSN: 1875-5402 (Electronic) Linking ISSN: 13862073 NLM ISO Abbreviation: Comb Chem High Throughput Screen Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Docking Simulation*, Acridines/*pharmacology , Antineoplastic Agents/*pharmacology, Acridines/chemical synthesis ; Acridines/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure