المؤلفون: Chen B; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA Chenb@medimmune.com SimsG@MedImmune.com., Vousden KA; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK., Naiman B; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Turman S; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Sun H; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Wang S; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.; Viela Bio, Gaithersburg, Maryland, USA., Vinall LMK; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK., Kemp BP; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK., Kasturiangan S; Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, USA., Rees DG; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, UK., Grant E; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Hinrichs MJ; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Eck S; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., DiGiandomenico A; Microbial Sciences, MedImmune, LLC, Gaithersburg, Maryland, USA., Jack Borrok M; Department of Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland, USA., Ly N; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Xiong X; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Gonzalez C; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Morehouse C; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Wang Y; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Zhou Y; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Cann J; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Zhao W; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Koelkebeck H; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Okubo K; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Mayadas TN; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Howe D; Department of Clinical Development, MedImmune Ltd, Granta Park, Great Abington, UK., Griffiths J; Department of Translational Medicine, MedImmune LLC, Gaithersburg, Maryland, USA., Kolbeck R; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Herbst R; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA., Sims GP; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA Chenb@medimmune.com SimsG@MedImmune.com.

المصدر: Annals of the rheumatic diseases [Ann Rheum Dis] 2019 Feb; Vol. 78 (2), pp. 228-237. Date of Electronic Publication: 2018 Nov 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Anti-Idiotypic/*pharmacology , Antigen-Antibody Complex/*drug effects , Autoimmune Diseases/*drug therapy , Immunologic Factors/*pharmacology , Receptors, IgG/*immunology, Animals ; Antibodies, Antineutrophil Cytoplasmic/immunology ; Antigen-Antibody Complex/immunology ; Autoimmune Diseases/immunology ; Dendritic Cells/immunology ; Humans ; Immunoglobulin G/immunology ; Interleukin-6/immunology ; Macaca fascicularis ; Mice ; Mice, Transgenic ; Neutrophils/immunology ; Reactive Oxygen Species/immunology ; Tumor Necrosis Factor-alpha/immunology