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1دورية أكاديمية
المؤلفون: Christopher C. Presley, Charles K. Perry, Elizabeth S. Childress, Matthew J. Mulder, Vincent B. Luscombe, Alice L. Rodriguez, Colleen M. Niswender, P. Jeffrey Conn, Craig W. Lindsley
المصدر: ACS Omega, Vol 4, Iss 7, Pp 12782-12789 (2019)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2470-1343
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المؤلفون: Madeline F, Long, Rory A, Capstick, Paul K, Spearing, Julie L, Engers, Alison R, Gregro, Sean R, Bollinger, Sichen, Chang, Vincent B, Luscombe, Alice L, Rodriguez, Hyekyung P, Cho, Colleen M, Niswender, Thomas M, Bridges, P Jeffrey, Conn, Craig W, Lindsley, Darren W, Engers, Kayla J, Temple
المصدر: Bioorg Med Chem Lett
مصطلحات موضوعية: Structure-Activity Relationship, Pyrimidines, Dose-Response Relationship, Drug, Molecular Structure, Receptor, Muscarinic M4, Drug Discovery, Humans, Article
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المؤلفون: Changho Han, J. Scott Daniels, Alice L. Rodriguez, Colleen M. Niswender, Alison R. Gregro, P. Jeffrey Conn, Michael R. Wood, Craig W. Lindsley, Katrina A. Bollinger, Michael W. Wood, Mark E. Duggan, Sichen Chang, Darren W. Engers, Atin Lamsal, Ryan D. Morrison, Andrew S. Felts, Trevor C. Chopko, Nicholas J. Brandon, Nathalie Schnetz-Boutaud, Vincent B. Luscombe, Hyekyung P. Cho, Mike Poslusney, Carrie K. Jones, Donald F. Stec, Thomas M. Bridges, Michael Bubser, Bruce J. Melancon
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:2224-2228
مصطلحات موضوعية: chemistry.chemical_classification, 010405 organic chemistry, Stereochemistry, Metabolite, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Metabolism, 01 natural sciences, Biochemistry, 0104 chemical sciences, Cns penetration, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, Molecular Medicine, Penetrant (biochemical), Molecular Biology, Aldehyde oxidase, Tricyclic
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المؤلفون: Colleen M. Niswender, Christopher C Presley, P. Jeffrey Conn, Vincent B. Luscombe, Alice L. Rodriguez, Charles K. Perry, Craig W. Lindsley, Matthew J. Mulder, Elizabeth S. Childress
المصدر: ACS Omega, Vol 4, Iss 7, Pp 12782-12789 (2019)
مصطلحات موضوعية: Molecular switch, Cytochrome, biology, Ligand, General Chemical Engineering, Metabolite, Allosteric regulation, General Chemistry, Combinatorial chemistry, lcsh:Chemistry, chemistry.chemical_compound, lcsh:QD1-999, chemistry, Biotransformation, In vivo, biology.protein, G protein-coupled receptor
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المؤلفون: Alice L. Rodriguez, P. Jeffrey Conn, Allison R. Gregro, Michael Bubser, Mark E. Dugan, Colleen M. Niswender, Leah C. Konkol, Michael W. Wood, Darren W. Engers, Craig W. Lindsley, Jeanette L. Bertron, Bruce J. Melancon, Sean R. Bollinger, Thomas M. Bridges, Samantha E. Yohn, Vincent B. Luscombe, Andrew S. Felts, Michael R. Wood, Carrie K. Jones, Nicholas J. Brandon, Katrina A. Bollinger
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:1714-1718
مصطلحات موضوعية: Allosteric modulator, 010405 organic chemistry, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Computational biology, 01 natural sciences, Biochemistry, 0104 chemical sciences, Pyridazine, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, medicine, Molecular Medicine, Moiety, Pharmaceutical sciences, Molecular Biology
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المؤلفون: Michael S. Poslusney, Alice L. Rodriguez, P. Jeffrey Conn, Craig W. Lindsley, Colleen M. Niswender, Vincent B. Luscombe, Darren W. Engers, Thomas M. Bridges, Katrina A. Bollinger, Michael R. Wood, Bruce J. Melancon, James M. Salovich
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:362-366
مصطلحات موضوعية: Bicyclic molecule, 010405 organic chemistry, Hydrogen bond, Chemistry, Stereochemistry, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Allosteric regulation, Pharmaceutical Science, Carboxamide, Pyrazole, 01 natural sciences, Biochemistry, First generation, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Intramolecular force, Drug Discovery, medicine, Molecular Medicine, Moiety, Molecular Biology
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المؤلفون: Colleen M. Niswender, Craig W. Lindsley, Andrew S. Felts, Vincent B. Luscombe, P. Jeffrey Conn, Hyekyung P. Cho, Elizabeth S. Childress, Megan M. Breiner, Joshua M. Wieting, Kyle A. Emmitte, Madeline F. Long, Alice L. Rodriguez, Anna L. Blobaum
المصدر: Journal of Medicinal Chemistry. 62:378-384
مصطلحات موضوعية: 0303 health sciences, Pyrimidine, medicine.drug_class, Stereochemistry, Allosteric regulation, Carboxamide, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, chemistry, Metabotropic glutamate receptor, Drug Discovery, Pyridine, medicine, Molecular Medicine, Structure–activity relationship, Selectivity, Receptor, 030304 developmental biology
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المؤلفون: Anna L. Blobaum, Jerri M. Rook, Jonathan W. Dickerson, Colleen M. Niswender, Julie L. Engers, Hekyung P Cho, Elizabeth S. Childress, Darren W. Engers, Rory A. Capstick, P. Jeffrey Conn, Craig W. Lindsley, Vincent B. Luscombe, Madeline F. Long
المصدر: ACS Medicinal Chemistry Letters. 9:917-922
مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.drug_class, Organic Chemistry, Allosteric regulation, Carboxamide, Pharmacology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Drug Discovery, Pyridine, Toxicity, medicine, Potency, Cholinergic, 030217 neurology & neurosurgery, EC50
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المؤلفون: Carole J. R. Bataille, Daniel Lucy, Vincent B Luscombe, Angela J. Russell, David R. Greaves
المصدر: DNA and cell biology. 39(11)
مصطلحات موضوعية: 0301 basic medicine, Inflammation, Enteroendocrine cell, Biology, Ligands, Proinflammatory cytokine, Receptors, G-Protein-Coupled, 03 medical and health sciences, 0302 clinical medicine, Immune system, Phagocytosis, Genetics, medicine, GPR84, Humans, Receptor, Molecular Biology, Orphan receptor, Macrophages, Fatty Acids, Cell Biology, General Medicine, Cell biology, Gastrointestinal Tract, 030104 developmental biology, 030220 oncology & carcinogenesis, Free fatty acid receptor, medicine.symptom, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be133c5efd113960b8de6978182e933
https://pubmed.ncbi.nlm.nih.gov/33001759 -
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المؤلفون: Thomas M. Bridges, Rory A. Capstick, Alice L. Rodriguez, Paul K. Spearing, Madeline F. Long, Vincent B. Luscombe, P. Jeffrey Conn, Alison R. Gregro, Sichen Chang, Julie L. Engers, Hyekyung P. Cho, Sean R. Bollinger, Colleen M. Niswender, Darren W. Engers, Kayla J. Temple, Craig W. Lindsley
المصدر: Bioorganic & Medicinal Chemistry Letters. 53:128416
مصطلحات موضوعية: chemistry.chemical_classification, Allosteric modulator, Pyrimidine, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, chemistry, Drug Discovery, Molecular Medicine, Molecular Biology, Tricyclic