المؤلفون: Vincent T. Metzger, Daniel C. Cannon, Jeremy J. Yang, Stephen L. Mathias, Cristian G. Bologa, Anna Waller, Stephan C. Schürer, Dušica Vidović, Keith J. Kelleher, Timothy K. Sheils, Lars Juhl Jensen, Christophe G. Lambert, Tudor I. Oprea, Jeremy S. Edwards

المصدر: PeerJ, Vol 12, p e17470 (2024)

مصطلحات موضوعية: Text mining, Diseases, Drug targets, Named entity recognition, Understudied protein, Disease ontology, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://peerj.com/articles/17470.pdf; https://peerj.com/articles/17470/; https://doaj.org/toc/2167-8359

URL الوصول: https://doaj.org/article/960d5f8e591045c1b0baec822e03ab67

المؤلفون: Keith J Kelleher, Timothy K Sheils, Stephen L Mathias, Jeremy J Yang, Vincent T Metzger, Vishal B Siramshetty, Dac-Trung Nguyen, Lars Juhl Jensen, Dušica Vidović, Stephan C Schürer, Jayme Holmes, Karlie R Sharma, Ajay Pillai, Cristian G Bologa, Jeremy S Edwards, Ewy A Mathé, Tudor I Oprea

المصدر: Kelleher, K J, Sheils, T K, Mathias, S L, Yang, J J, Metzger, V T, Siramshetty, V B, Nguyen, D-T, Jensen, L J, Vidovic, D, Schurer, S C, Holmes, J, Sharma, K R, Pillai, A, Bologa, C G, Edwards, J S, Mathe, E A & Oprea, T 2023, ' Pharos 2023 : an integrated resource for the understudied human proteome ', Nucleic Acids Research, vol. 51, no. D1, gkac1033, pp. D1405-D1416 . https://doi.org/10.1093/nar/gkac1033

مصطلحات موضوعية: ONTOLOGY, DATABASE, DISCOVERY, Genetics, MAP, VISUALIZATION

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d65450ea96a731b4d232b473fbf4326
https://curis.ku.dk/portal/da/publications/pharos-2023(f032f17b-c49b-4c10-9eb3-36e30874c00f).html

المؤلفون: Eryk Kropiwnicki, Jessica L. Binder, Jeremy J. Yang, Jayme Holmes, Alexander Lachmann, Daniel J. B. Clarke, Timothy Sheils, Keith J. Kelleher, Vincent T. Metzger, Cristian G. Bologa, Tudor I. Oprea, Avi Ma'ayan

المصدر: Current Protocols. 2

مصطلحات موضوعية: Machine Learning, Medical Laboratory Technology, Genome, General Immunology and Microbiology, SARS-CoV-2, General Neuroscience, Databases, Genetic, COVID-19, Humans, Proteins, Health Informatics, General Pharmacology, Toxicology and Pharmaceutics, General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53d391a4c0ca33b04fd8138d9b5618
https://doi.org/10.1002/cpz1.355

المؤلفون: Vincent T Metzger, James O Lloyd-Smith, Leor S Weinberger

المصدر: PLoS Computational Biology, Vol 7, Iss 3, p e1002015 (2011)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3060167?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/35ddb37f5e694ea5b3da9d0117802d25

المؤلفون: Gary A. Huber, Changsun Eun, Peter M. Kekenes-Huskey, Vincent T. Metzger, J. Andrew McCammon

المصدر: Metzger, VT; Eun, C; Kekenes-Huskey, PM; Huber, G; & McCammon, JA. (2014). Electrostatic channeling in P. falciparum DHFR-TS: Brownian dynamics and smoluchowski modeling. Biophysical Journal, 107(10), 2394-2402. doi: 10.1016/j.bpj.2014.09.039. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0pz7v7dn
Biophysical journal, vol 107, iss 10

مصطلحات موضوعية: Models, Molecular, Surface Properties, Plasmodium falciparum, Static Electricity, Substrate channeling, Biophysics, Electric charge, Rare Diseases, Species Specificity, Multienzyme Complexes, Models, Catalytic Domain, parasitic diseases, Static electricity, heterocyclic compounds, biology, Chemistry, Molecular, Charge density, Active site, Thymidylate Synthase, Biological Sciences, Tetrahydrofolate Dehydrogenase, Crystallography, Good Health and Well Being, Ionic strength, Chemical physics, Physical Sciences, Chemical Sciences, Solvents, biology.protein, Brownian dynamics, Protein quaternary structure, Proteins and Nucleic Acids

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c55d9f91262a5f320351fd5c109df7
https://doi.org/10.1016/j.bpj.2014.09.039

المؤلفون: J. Andrew McCammon, Barry J. Grant, Vincent T. Metzger, Peter M. Kekenes-Huskey

المصدر: Protein Science. 21:1429-1443

مصطلحات موضوعية: SERCA, biology, Endoplasmic reticulum, ATPase, Allosteric regulation, chemistry.chemical_element, Calcium, Biochemistry, Cell biology, Cytosol, Protein structure, chemistry, biology.protein, Molecular Biology, Calcium signaling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0071fa84f794075297b84f5030b705fd
https://doi.org/10.1002/pro.2129

المؤلفون: Changsun Eun, J. Andrew McCammon, Vincent T. Metzger, Peter M. Kekenes-Huskey

المصدر: Eun, C; Kekenes-Huskey, PM; Metzger, VT; & McCammon, JA. (2014). A model study of sequential enzyme reactions and electrostatic channeling. Journal of Chemical Physics, 140(10). doi: 10.1063/1.4867286. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0s60638m
The Journal of chemical physics, vol 140, iss 10

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Kinetics, Static Electricity, General Physics and Astronomy, Biological Molecules and Networks, Reaction rate, Chemical kinetics, Engineering, Models, Static electricity, Physical and Theoretical Chemistry, chemistry.chemical_classification, Chemical Physics, Molecular biophysics, Molecular, Substrate (chemistry), Electrostatics, Enzymes, Enzyme, chemistry, Physical Sciences, Chemical Sciences, Biophysics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53940d1dc9d837222e3db138315f4bfb
https://pubmed.ncbi.nlm.nih.gov/24628210

المؤلفون: Changsun Eun, Peter M. Kekenes-Huskey, Vincent T. Metzger, J. Andrew McCammon

المصدر: Biophysical Journal. 106(2)

مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, Stereochemistry, Kinetics, Biophysics, Substrate (chemistry), Reaction rate, chemistry.chemical_compound, Enzyme, Computational chemistry, Elementary reaction, Diffusion limited enzyme, Enzyme kinetics, Methylene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad8eabf888f537b904aef90a5909245

المؤلفون: Peter M, Kekenes-Huskey, Vincent T, Metzger, Barry J, Grant, J, Andrew McCammon

المصدر: Protein science : a publication of the Protein Society. 21(10)

مصطلحات موضوعية: Principal Component Analysis, Binding Sites, Thermodynamics, Calcium, Calcium Signaling, Articles, Molecular Dynamics Simulation, Databases, Protein, Protein Structure, Tertiary, Sarcoplasmic Reticulum Calcium-Transporting ATPases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d09f20ff6be30ae4e600901e759ac993
https://pubmed.ncbi.nlm.nih.gov/22821874

المؤلفون: James O. Lloyd-Smith, Vincent T. Metzger, Leor S. Weinberger

المساهمون: De Boer, Rob J

المصدر: PLoS computational biology, vol 7, iss 3
PLoS Computational Biology
PLoS Computational Biology, Vol 7, Iss 3, p e1002015 (2011)
Metzger, VT; Lloyd-Smith, JO; & Weinberger, LS. (2011). Autonomous targeting of infectious superspreaders using engineered transmissible therapies. PLoS Computational Biology, 7(3). doi: 10.1371/journal.pcbi.1002015. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9js4s3ms

مصطلحات موضوعية: Drug Resistance, Prevalence, Population Modeling, HIV Infections, Disease, Drug resistance, Protein Engineering, Mathematical Sciences, 0302 clinical medicine, Immunodeficiency Viruses, Models, Viral, 030212 general & internal medicine, lcsh:QH301-705.5, Pathogen, Clinical Trials as Topic, 0303 health sciences, education.field_of_study, Ecology, Statistical, Biological Sciences, 3. Good health, Infectious Diseases, Pharmaceutical Preparations, Computational Theory and Mathematics, Modeling and Simulation, HIV/AIDS, Synthetic Biology, Infection, Viral load, Research Article, Biotechnology, Anti-HIV Agents, Evolution, Bioinformatics, Population, Biology, Microbiology, Evolution, Molecular, Vaccine Related, 03 medical and health sciences, Cellular and Molecular Neuroscience, Acquired immunodeficiency syndrome (AIDS), Clinical Research, Virology, Viruslike Particles, Information and Computing Sciences, Drug Resistance, Viral, Evolutionary Modeling, Genetics, medicine, Humans, education, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Acquired Immunodeficiency Syndrome, Models, Statistical, Prevention, Computational Biology, Molecular, Genetic Therapy, medicine.disease, Good Health and Well Being, lcsh:Biology (General), Infectious disease (medical specialty), Communicable Disease Control, Mutation, Africa, Immunology, Immunization, Infectious Disease Modeling

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7adfa13ad9fd145d6affdf4f5ee6e681
https://doi.org/10.1371/journal.pcbi.1002015