المؤلفون: Schmidt D; University of Freiburg Medical Center, Freiburg, Germany., Endres C; Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Hoefflin R; Weizmann Institute of Science, Rehovot, Israel., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Zwick M; University Medical Center Freiburg, Freiburg, Germany., Karantzelis N; University of Freiburg Medical Center, Freiburg, Germany., Staehle HF; University of Freiburg Medical Center, Freiburg, Germany., Vinnakota JM; University of Freiburg Medical Center, Freiburg, Germany., Duquesne S; Albert-Ludwigs-University, Freiburg, Germany., Mozaffari Jovein M; University of Freiburg Medical Center, Freiburg, Germany., Pfeifer D; University Medical Center Freiburg, Freiburg, Germany., Becker H; University of Freiburg Medical Center, Freiburg, Germany., Blazar BR; University of Minnesota, Minneapolis, MN, United States., Zähringer A; University of Freiburg Medical Center, Freiburg, Germany., Duyster J; Freiburg University Hospital, Freiburg, Germany., Brummer T; University of Freiburg, Freiburg, Germany., Boerries M; University of Freiburg, Freiburg, Germany., Baumeister J; RWTH Aachen University, Aachen, Germany., Shoumariyeh K; Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Li J; Cambridge Institute for Medical Research, Cambridge, United Kingdom., Green AR; Cambridge Stem Cell Institute, Cambridge, United Kingdom., Heidel FH; Hannover Medical School, Hannover, Germany., Tirosh I; Weizmann Institute of Science, Rehovot, Israel., Pahl HL; Department of Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany, Freiburg, Germany., Leimkühler N; Essen University Hospital, Essen, Germany., Köhler N; University of Freiburg Medical Center, Freiburg, Germany., de Toledo MAS; RWTH Aachen University, Aachen, Germany., Koschmieder S; RWTH Aachen University, Aachen, NRW, Germany., Zeiser R; University of Freiburg Medical Center, Freiburg, Germany.

المصدر: Cancer research [Cancer Res] 2024 Jun 17. Date of Electronic Publication: 2024 Jun 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

المؤلفون: Vinnakota JM; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, 79104 Freiburg, Germany., Adams RC; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Medicine, University of Queensland, 4006 Brisbane, QLD, Australia.; QIMR Berghofer Medical Research Institute, 4072 Brisbane, QLD, Australia., Athanassopoulos D; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Schmidt D; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, 79104 Freiburg, Germany., Biavasco F; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Zähringer A; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Erny D; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany., Schwabenland M; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany., Langenbach M; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, 79104 Freiburg, Germany., Wenger V; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Salié H; Department of Medicine II-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Cook J; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany., Mossad O; Faculty of Biology, Albert-Ludwigs-University, 79104 Freiburg, Germany.; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79110 Freiburg, Germany., Dersch R; Clinic of Neurology and Neurophysiology, Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Rauer S; Clinic of Neurology and Neurophysiology, Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Duquesne S; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Monaco G; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany.; Single-Cell Omics Platform Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Institute for Transfusion Medicine and Gene Therapy, Medical Center-University of Freiburg, 79106 Freiburg, Germany., Wolf P; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Department of Urology, Medical Center-University of Freiburg, 79106 Freiburg, Germany., Blank T; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany., Häne P; Institute of Experimental Immunology at the University of Zürich, CH-8057 Zürich, Switzerland., Greter M; Institute of Experimental Immunology at the University of Zürich, CH-8057 Zürich, Switzerland., Becher B; Institute of Experimental Immunology at the University of Zürich, CH-8057 Zürich, Switzerland., Henneke P; Center for Chronic Immunodeficiency and Center for Pediatrics, University Medical Center Freiburg, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany., Pfeifer D; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Blazar BR; Masonic Cancer Center and Department of Pediatrics, Division of Blood and Marrow Transplant and Cellular Therapy, University of Minnesota, Minneapolis, MN 55454, USA., Duyster J; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Boerries M; Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79110 Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between DKFZ and Medical Center - University of Freiburg and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Köhler N; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany., Chhatbar CM; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany., Bengsch B; Department of Medicine II-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany., Prinz M; Institute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany.; Center for Neuro Modulation, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Zeiser R; Department of Medicine I-Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; CIBSS-Center for Integrative Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between DKFZ and Medical Center - University of Freiburg and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

المصدر: Science translational medicine [Sci Transl Med] 2024 Jun 12; Vol. 16 (751), pp. eadj9672. Date of Electronic Publication: 2024 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Microglia*/drug effects , Microglia*/metabolism , Microglia*/pathology , Immunotherapy*/adverse effects , Programmed Cell Death 1 Receptor*/metabolism , Programmed Cell Death 1 Receptor*/antagonists & inhibitors , Central Nervous System*/pathology , Central Nervous System*/drug effects, Animals ; Humans ; Mice, Inbred C57BL ; Syk Kinase/metabolism ; Mice

المؤلفون: Vinnakota JM; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Biavasco F; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schwabenland M; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Chhatbar C; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Adams RC; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Erny D; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Duquesne S; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., El Khawanky N; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Medicine III, School of Medicine, Technical University of Munich, Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany., Schmidt D; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Fetsch V; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Zähringer A; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Salié H; Department of Medicine II, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Athanassopoulos D; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Braun LM; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Javorniczky NR; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Ho JNHG; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Kierdorf K; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Marks R; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Wäsch R; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Simonetta F; Division of Hematology, Geneva University Hospitals Geneva, Geneva, Switzerland., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Medical Center, University of Freiburg, Freiburg, Germany., Pfeifer D; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Monaco G; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Single-Cell Omics Platform Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Institute for Transfusion Medicine and Gene Therapy, Medical Center, University of Freiburg, Freiburg, Germany., Capitini C; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Fry TJ; Center for Cancer and Blood Disorders, Children's Hospital Colorado and Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Blank T; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany., Blazar BR; Masonic Cancer Center and Department of Pediatrics, Division of Blood & Marrow Transplant & Cellular Therapy, University of Minnesota, Minneapolis, MN, USA., Wagner E; Department of Hematology and Medical Oncology, Johannes Gutenberg-University Medical Center, Mainz, Germany., Theobald M; Department of Hematology and Medical Oncology, Johannes Gutenberg-University Medical Center, Mainz, Germany., Sommer C; Institute of Neuropathology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany., Stelljes M; Department of Medicine/Hematology and Oncology, University of Münster, Münster, Germany., Reicherts C; Department of Medicine/Hematology and Oncology, University of Münster, Münster, Germany., Jeibmann A; Institute of Neuropathology, University Hospital Münster, Münster, Germany., Schittenhelm J; Department of Neuropathology, Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany., Monoranu CM; Institute of Pathology, University of Würzburg, Würzburg, Germany., Rosenwald A; Institute of Pathology, University of Würzburg, Würzburg, Germany., Kortüm M; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany., Rasche L; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany., Einsele H; Department of Internal Medicine 2, University Hospital of Würzburg, Würzburg, Germany., Meyer PT; Department of Nuclear Medicine, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Brumberg J; Department of Nuclear Medicine, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Völkl S; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Erlangen, Germany., Mackensen A; Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Erlangen, Germany., Coras R; Department of Neuropathology, University Hospital Erlangen, Erlangen, Germany., von Bergwelt-Baildon M; Department of Medicine III, Hematology/Oncology, University Hospital, Ludwig-Maximilians Universität (LMU) Munich, Munich, Germany., Albert NL; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Bartos LM; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Brendel M; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Holzgreve A; Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany., Mack M; Department of Nephrology, University of Regensburg, Regensburg, Germany., Boerries M; Institute of Medical Bioinformatics and Systems Medicine, Medical Center, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany., Mackall CL; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford, CA, USA., Duyster J; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Henneke P; Division of Pediatric Infectious Diseases, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Priller J; Department of Psychiatry, Technischen Universität München (TUM), Munich, Germany., Köhler N; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Strübing F; Center for Neuropathology and Prion Research, University Hospital, LMU Munich, Munich, Germany., Bengsch B; Department of Medicine II, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ruella M; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USA.; Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Subklewe M; Department of Medicine III, Hematology/Oncology, University Hospital, Ludwig-Maximilians Universität (LMU) Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center (DKFZ), Heidelberg, Germany., von Baumgarten L; German Cancer Consortium (DKTK), Partner Site Munich, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Neuro-Oncology, Department of Neurosurgery, University Hospital, LMU Munich, Munich, Germany., Gill S; Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA, USA.; Division of Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA., Prinz M; Institute for Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Zeiser R; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; German Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany. robert.zeiser@uniklinik-freiburg.de.; Signalling Research Centres BIOSS and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.

المصدر: Nature cancer [Nat Cancer] 2024 May 13. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

المؤلفون: Adams RC; Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Carter-Cusack D; Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Llanes GT; Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Hunter CR; Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Vinnakota JM; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs University, Freiburg, Germany., Ruitenberg MJ; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Vukovic J; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Bertolino P; Centenary Institute and University of Sydney, AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia., Chand KK; UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Wixey JA; UQ Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.; Perinatal Research Centre, Royal Brisbane and Women's Hospital, Herston, Brisbane, QLD, Australia., Nayler SP; Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia., Hill GR; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA.; Division of Oncology, Department of Medicine, University of Washington, Seattle, WA., Furlan SN; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA., Zeiser R; Department of Medicine I, Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.; German Cancer Consortium, Partner Site Freiburg, Freiburg, Germany, and German Cancer Research Centre, Heidelberg, Germany., MacDonald KPA; Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

المصدر: Blood [Blood] 2024 Mar 07; Vol. 143 (10), pp. 912-929.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Graft vs Host Disease*/etiology , Hematopoietic Stem Cell Transplantation*/adverse effects, Humans ; Mice ; Animals ; Neuroinflammatory Diseases ; CD4-Positive T-Lymphocytes ; Macrophages/pathology ; Receptor Protein-Tyrosine Kinases ; Receptors, Colony-Stimulating Factor

المؤلفون: Maas-Bauer K; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Stell AV; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Yan KL; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., de Vega E; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Vinnakota JM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Unger S; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Núñez N; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Norona J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Talvard-Balland N; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Koßmann S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schwan C; Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty, University of Freiburg, Freiburg, Germany., Miething C; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Martens US; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty, University of Freiburg, Freiburg, Germany., Shoumariyeh K; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between German Cancer Research Center (DKFZ) and Medical Center - University of Freiburg, Freiburg, Germany., Nestor RP; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Duquesne S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Hanke K; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Rackiewicz M; Department of Biology, University of Fribourg, Fribourg, Switzerland.; Department of Dermatology, Medical Center, University of Freiburg, Freiburg, Germany., Hu Z; Department of Biology, University of Fribourg, Fribourg, Switzerland.; Department of Dermatology, Medical Center, University of Freiburg, Freiburg, Germany., El Khawanky N; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Taromi S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Andrlova H; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Faraidun H; Faculty of Biology, University of Freiburg, Freiburg, Germany., Walter S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Pfeifer D; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Follo M; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Waldschmidt J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Melchinger W; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Rassner M; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Wehr C; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schmitt-Graeff A; Institute of Pathology, University Hospital Freiburg, Freiburg, Germany., Halbach S; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between German Cancer Research Center (DKFZ) and Medical Center - University of Freiburg, Freiburg, Germany.; IMMZ, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Liao J; Department of Medicine, University of Arizona, Tucson, USA., Häcker G; IMMH, University Hospital Freiburg, Faculty of Medicine, Freiburg, Germany., Brummer T; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between German Cancer Research Center (DKFZ) and Medical Center - University of Freiburg, Freiburg, Germany.; IMMZ, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; Signaling Research Centres BIOSS and CIBSS - Centre for Integrative Biological Signaling Studies, University of Freiburg, Freiburg, Germany., Dengjel J; Department of Biology, University of Fribourg, Fribourg, Switzerland.; Department of Dermatology, Medical Center, University of Freiburg, Freiburg, Germany., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Grosse R; Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty, University of Freiburg, Freiburg, Germany.; CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Tugues S; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Blazar BR; Department of Pediatrics, Division of Blood & Marrow Transplant & Cellular Therapy, University of Minnesota, Minneapolis, MN, USA., Becher B; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Boerries M; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between German Cancer Research Center (DKFZ) and Medical Center - University of Freiburg, Freiburg, Germany.; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Zeiser R; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between German Cancer Research Center (DKFZ) and Medical Center - University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; Signaling Research Centres BIOSS and CIBSS - Centre for Integrative Biological Signaling Studies, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.

المصدر: Nature communications [Nat Commun] 2024 Jan 10; Vol. 15 (1), pp. 446. Date of Electronic Publication: 2024 Jan 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: rho-Associated Kinases*/genetics , Graft vs Host Disease*/drug therapy, Humans ; Animals ; Mice ; Signal Transduction ; NF-kappa B ; Adrenal Cortex Hormones/pharmacology ; Adrenal Cortex Hormones/therapeutic use

المؤلفون: Isbell LK; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Tschuch C; Charles River Discovery Research Services GmbH, Freiburg, Germany., Doostkam S; Institute of Neuropathology, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Waldeck S; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; German Cancer Consortium (DKTK), partner site Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany., Shoumariyeh K; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; German Cancer Consortium (DKTK), partner site Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany., Lenhard D; Charles River Discovery Research Services GmbH, Freiburg, Germany., Schaefer HE; Department of Pathology, University of Freiburg, Freiburg, Germany., Reinacher PC; Department of Stereotactic and Functional Neurosurgery, Medical Faculty, University of Freiburg, Freiburg, Germany.; Fraunhofer Institute for Laser Technology (ILT), Aachen, Germany., Bartsch I; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Pantic M; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Vinnakota JM; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Kakkassery V; Department of Ophthalmology, University of Luebeck, Luebeck, Germany., Schorb E; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany., Scherer F; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; German Cancer Consortium (DKTK), partner site Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany., Frey AV; Department of Pathology, University of Freiburg, Freiburg, Germany., Boerries M; Institute of Medical Bioinformatics and Systems Medicine (IBSM), Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; German Cancer Consortium (DKTK), partner site Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany., Illerhaus G; Clinic of Hematology, Oncology and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany., Duyster J; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; German Cancer Consortium (DKTK), partner site Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany., Schueler J; Charles River Discovery Research Services GmbH, Freiburg, Germany., von Bubnoff N; Department of Medicine I, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany.; German Cancer Consortium (DKTK), partner site Freiburg, Germany and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Hematology and Oncology, University Hospital Schleswig-Holstein, Luebeck, Germany.

المصدر: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2023 Apr; Vol. 49 (2), pp. e12899.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 7609829 Publication Model: Print Cited Medium: Internet ISSN: 1365-2990 (Electronic) Linking ISSN: 03051846 NLM ISO Abbreviation: Neuropathol Appl Neurobiol Subsets: MEDLINE

مواضيع طبية MeSH: Retinal Neoplasms*/diagnosis , Retinal Neoplasms*/drug therapy , Retinal Neoplasms*/pathology , Central Nervous System Neoplasms*/pathology , Lymphoma, Large B-Cell, Diffuse*/drug therapy , Lymphoma, Large B-Cell, Diffuse*/genetics , Lymphoma, Large B-Cell, Diffuse*/pathology, Humans ; Animals ; Mice ; Heterografts ; Vitreous Body/metabolism ; Vitreous Body/pathology ; Central Nervous System/pathology ; Retina/metabolism

المؤلفون: Ho JNHG; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Schmidt D; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Lowinus T; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Ryoo J; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Dopfer EP; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Gonzalo Núñez N; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Costa-Pereira S; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Toffalori C; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milano, Italy., Punta M; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milano, Italy.; Center for Omics Sciences, IRCCS San Raffaele Institute, Milano, Italy., Fetsch V; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Wertheimer T; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Rittmann MC; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Braun LM; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Follo M; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Briere C; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Vinnakota JM; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Langenbach M; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Koppers F; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Shoumariyeh K; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research, Center (DKFZ), Heidelberg, Germany., Engel H; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Rückert T; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Märklin M; Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tuebingen, Tuebingen, Germany.; Deutsche Forschungsgemeinschaft Cluster of Excellence 2180 'Image-guided and Functional Instructed Tumor Therapy,' University of Tuebingen, Tuebingen, Germany., Holzmayer S; Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tuebingen, Tuebingen, Germany.; Deutsche Forschungsgemeinschaft Cluster of Excellence 2180 'Image-guided and Functional Instructed Tumor Therapy,' University of Tuebingen, Tuebingen, Germany., Illert AL; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research, Center (DKFZ), Heidelberg, Germany., Magon F; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Andrieux G; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research, Center (DKFZ), Heidelberg, Germany.; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Duquesne S; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Pfeifer D; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany., Staniek J; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany.; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, Medical Centre., Rizzi M; Department of Rheumatology and Clinical Immunology, Faculty of Medicine, Medical Centre.; Signalling Research Centres BIOSS and CIBSS - Centre for Integrative Biological, Signalling Studies, and., Miething C; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research, Center (DKFZ), Heidelberg, Germany., Köhler N; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Duyster J; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research, Center (DKFZ), Heidelberg, Germany., Menssen HD; Novartis Pharma, Basel, Switzerland., Boerries M; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research, Center (DKFZ), Heidelberg, Germany.; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Buescher JM; Max-Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Cabezas-Wallscheid N; Max-Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Blazar BR; Division of Blood & Marrow Transplant and Cellular Therapy, Department of Pediatrics, University of Minnesota, Minneapolis, MN; and., Apostolova P; Max-Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Johns Hopkins University, Baltimore, MD., Vago L; Unit of Immunogenetics, Leukemia Genomics and Immunobiology, Division of Immunology, Transplantation and Infectious Disease, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milano, Italy., Pearce EL; Max-Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.; The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Johns Hopkins University, Baltimore, MD., Becher B; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Zeiser R; Clinic of Internal Medicine I, Hematology, Oncology, and Stem Cell Transplantation, Faculty of Medicine, Medical Centre, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research, Center (DKFZ), Heidelberg, Germany.; Signalling Research Centres BIOSS and CIBSS - Centre for Integrative Biological, Signalling Studies, and.

المصدر: Blood [Blood] 2022 Sep 08; Vol. 140 (10), pp. 1167-1181.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/genetics , Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism, Animals ; Apoptosis ; Humans ; Major Histocompatibility Complex ; Mice ; Proto-Oncogene Proteins c-mdm2/metabolism ; Transplantation, Homologous ; Up-Regulation

المؤلفون: El Khawanky N; Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Hughes A; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia., Yu W; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia., Myburgh R; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Comprehensive Cancer Center Zurich (CCCZ), Zurich, Switzerland., Matschulla T; Institute of Experimental and Clinical Pharmacology and Toxicology, Division II, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Taromi S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Medical and Life Sciences, University Furtwangen, Villingen-Schwenningen, Germany., Aumann K; Department of Pathology, Institute for Clinical Pathology, University Medical Center Freiburg, Freiburg, Germany., Clarson J; Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.; Department of Haematology, Royal Adelaide Hospital, Adelaide, SA, Australia., Vinnakota JM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Shoumariyeh K; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Miething C; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lopez AF; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia., Brown MP; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.; Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA, Australia.; Cancer Clinical Trials Unit, Department of Medical Oncology, Royal Adelaide Hospital, Adelaide, SA, Australia., Duyster J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Hein L; Institute of Experimental and Clinical Pharmacology and Toxicology, Division II, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Manz MG; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Comprehensive Cancer Center Zurich (CCCZ), Zurich, Switzerland., Hughes TP; Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.; Department of Haematology, Royal Adelaide Hospital, Adelaide, SA, Australia., White DL; Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia.; School of Biological Sciences, Faculty of Science, University of Adelaide, Adelaide, SA, Australia., Yong ASM; Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia. agnes.yong@health.wa.gov.au.; School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia. agnes.yong@health.wa.gov.au.; Department of Haematology, Royal Perth Hospital, Perth, WA, Australia. agnes.yong@health.wa.gov.au.; School of Medicine, The University of Western Australia, Perth, WA, Australia. agnes.yong@health.wa.gov.au., Zeiser R; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; Signaling Research Centres BIOSS and CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.

المصدر: Nature communications [Nat Commun] 2021 Nov 08; Vol. 12 (1), pp. 6436. Date of Electronic Publication: 2021 Nov 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Azacitidine/*administration & dosage , Immunotherapy, Adoptive/*methods , Interleukin-3 Receptor alpha Subunit/*immunology , Leukemia, Myeloid/*therapy , Single-Chain Antibodies/*immunology , Xenograft Model Antitumor Assays/*methods, Acute Disease ; Animals ; Cell Line, Tumor ; Cells, Cultured ; Cytotoxicity, Immunologic ; DNA Methylation/drug effects ; Enzyme Inhibitors/administration & dosage ; HEK293 Cells ; HL-60 Cells ; Humans ; Interleukin-3 Receptor alpha Subunit/metabolism ; Kaplan-Meier Estimate ; Leukemia, Myeloid/immunology ; Leukemia, Myeloid/pathology ; Mice, Knockout ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell/metabolism ; Receptors, Chimeric Antigen/immunology ; Receptors, Chimeric Antigen/metabolism ; Mice

المؤلفون: Vinnakota JM; Department of Medicine I - Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, Albert-Ludwigs-University, Freiburg, Germany., Zeiser R; Department of Medicine I - Medical Centre, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.

المصدر: Frontiers in immunology [Front Immunol] 2021 Oct 06; Vol. 12, pp. 748019. Date of Electronic Publication: 2021 Oct 06 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Central Nervous System/*drug effects , Central Nervous System Diseases/*etiology , Central Nervous System Infections/*immunology , Cerebrovascular Disorders/*etiology , Graft vs Host Disease/*etiology , Hematopoietic Stem Cell Transplantation/*adverse effects, Acute Disease ; Allografts/immunology ; Animals ; Anti-Infective Agents/adverse effects ; Anti-Infective Agents/therapeutic use ; Central Nervous System/immunology ; Central Nervous System Diseases/immunology ; Central Nervous System Infections/drug therapy ; Cerebrovascular Disorders/immunology ; Disease Models, Animal ; Female ; Graft vs Host Disease/diagnosis ; Graft vs Host Disease/immunology ; Graft vs Host Disease/prevention & control ; Humans ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/therapeutic use ; Male ; Mice ; Primates ; T-Lymphocytes/immunology ; T-Lymphocytes/transplantation

المؤلفون: Hamarsheh S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Osswald L; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Saller BS; Faculty of Biology, University of Freiburg, Freiburg, Germany.; Institute of Neuropathology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Unger S; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., De Feo D; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Vinnakota JM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Konantz M; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland., Uhl FM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Becker H; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lübbert M; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Shoumariyeh K; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schürch C; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Venhoff N; Clinic for Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schmitt-Graeff A; University of Freiburg, Freiburg, Germany., Duquesne S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Pfeifer D; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Cooper MA; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia., Lengerke C; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland., Boerries M; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany., Duyster J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany., Niemeyer CM; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany.; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Erlacher M; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany.; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Blazar BR; Division of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA., Becher B; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Groß O; Institute of Neuropathology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Biological Signalling Studies (BIOSS) and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Brummer T; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany.; Institute of Molecular Medicine and Cell Research (IMMZ), Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Freiburg, Germany., Zeiser R; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany. robert.zeiser@uniklinik-freiburg.de.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; Centre for Biological Signalling Studies (BIOSS) and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.

المصدر: Nature communications [Nat Commun] 2020 Apr 03; Vol. 11 (1), pp. 1659. Date of Electronic Publication: 2020 Apr 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Inflammasomes/*immunology , Myeloproliferative Disorders/*genetics , NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism , Proto-Oncogene Proteins p21(ras)/*genetics, Animals ; Cell Proliferation ; Gene Expression ; Hematopoiesis ; Humans ; Inflammasomes/metabolism ; Interleukin-1beta/metabolism ; Leukemia, Myeloid/etiology ; Leukemia, Myeloid/genetics ; Mice ; Mice, Inbred C57BL ; Molecular Targeted Therapy ; Myeloid Cells/metabolism ; NLR Proteins/metabolism ; Proto-Oncogene Proteins p21(ras)/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction