المؤلفون: Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J. Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W. Thoroughgood, Katie J. Simmons, Christopher G. Dowson, Colin W. G. Fishwick, Luiz Pedro S. de Carvalho, David I. Roper

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/66e59bce52674d29b83d6b33b62cc099

المؤلفون: Dean Rea, Christopher W. Thoroughgood, Luiz Pedro S. de Carvalho, S. Batson, Cesira de Chiara, Vita Majce, David I. Roper, Vilmos Fülöp, Colin W. G. Fishwick, Katie J. Simmons, Christopher G. Dowson, Stanislav Gobec, Adrian J. Lloyd

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Science, D-cycloserine, General Physics and Astronomy, chemical and pharmacologic phenomena, General Biochemistry, Genetics and Molecular Biology, Bacterial cell structure, Article, 03 medical and health sciences, Alanine racemase, medicine, Escherichia coli, Peptide Synthases, Phosphorylation, lcsh:Science, Antibiotics, Antitubercular, chemistry.chemical_classification, DNA ligase, Multidisciplinary, 030102 biochemistry & molecular biology, Escherichia coli Proteins, Cycloserine, Alanine Racemase, hemic and immune systems, General Chemistry, 3. Good health, QR, carbohydrates (lipids), 030104 developmental biology, Enzyme, chemistry, Biochemistry, Mechanism of action, lcsh:Q, medicine.symptom, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8c3d91c18a7a14bfd843d766186dd0
http://wrap.warwick.ac.uk/95976/1/WRAP-inhibition-D-Ala-D-Ala-ligase-phosphorylated-antibiotic-Roper-2017.pdf

المؤلفون: Janez Košmrlj, Damijana Urankar, Luc Verschaeve, Vanessa Mathys, Marijan Kočevar, Cynthia Uythethofken, Kris Huygen, Slovenko Polanc, Davie Cappoen, Vita Majce

المصدر: European Journal of Medicinal Chemistry; Vol 74
European journal of medicinal chemistry

مصطلحات موضوعية: Antitubercular Agents, Imides, 01 natural sciences, Microbiology, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Potency, Viability assay, 030304 developmental biology, Pharmacology, 0303 health sciences, Mycobacterium bovis, biology, 010405 organic chemistry, Pharmacology. Therapy, Organic Chemistry, General Medicine, biology.organism_classification, 0104 chemical sciences, 3. Good health, Comet assay, Chemistry, chemistry, Mycobacterium ulcerans, Immunology, Growth inhibition, Drug Screening Assays, Antitumor, Mycobacterium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8563471742e589c275acf0ada4b92c74

المؤلفون: Slovenko Polanc, Marijan Kočevar, Vita Majce

المصدر: Tetrahedron Letters. 52:3287-3290

مصطلحات موضوعية: Fumaric acid, Organic Chemistry, Biochemistry, Catalysis, Solvent, chemistry.chemical_compound, chemistry, Drug Discovery, Organic chemistry, Amine gas treating, Piperidine, Acetonitrile, Isomerization, Microwave

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d647636df493d061372d4664e698b645
https://doi.org/10.1016/j.tetlet.2011.04.066

المؤلفون: Adrian J. Lloyd, Gašper Čadež, David I. Roper, Samo Turk, Slovenko Polanc, Stanislav Gobec, Vita Majce, S. Batson, Colin W. G. Fishwick, Matej Sova

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:1376-1379

مصطلحات موضوعية: Isostere, Structural similarity, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, Bacterial Proteins, Drug Discovery, Ethylamines, medicine, Moiety, Enzyme Inhibitors, Peptide Synthases, Carbon-Oxygen Ligases, Molecular Biology, Escherichia coli, chemistry.chemical_classification, DNA ligase, biology, Organic Chemistry, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Enzyme, Enterococcus, chemistry, Staphylococcus aureus, Drug Design, bacteria, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731ab3d627a493348a26230f2f944bb1
https://doi.org/10.1016/j.bmcl.2009.01.034

المؤلفون: Karen M. Ruane, David I. Roper, Vita Majce, Stanislav Gobec

مصطلحات موضوعية: Biophysics, Tripeptide, Peptidoglycan, Biology, medicine.disease_cause, Crystallography, X-Ray, Biochemistry, Bacterial cell structure, law.invention, chemistry.chemical_compound, Bacterial Proteins, Structural Biology, law, Genetics, medicine, Crystallization, chemistry.chemical_classification, DNA ligase, Pseudomonas aeruginosa, Substrate (chemistry), Condensed Matter Physics, Uridine Diphosphate N-Acetylmuramic Acid, carbohydrates (lipids), Enzyme, chemistry, Crystallization Communications

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98d16f6e091fe44e9ddcb1f7a4492b4
https://europepmc.org/articles/PMC3660887/

المؤلفون: Marijan Kočevar, Slovenko Polanc, Vita Majce

المصدر: ChemInform. 42

مصطلحات موضوعية: Solvent, Fumaric acid, chemistry.chemical_compound, chemistry, Amine gas treating, General Medicine, Piperidine, Acetonitrile, Combinatorial chemistry, Isomerization, Microwave, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::809fd108abf662685ad5a759cb988408
https://doi.org/10.1002/chin.201139024

المؤلفون: Slovenko Polanc, Vita Majce, Tamara Čimbora-Zovko, Maja Osmak, Ivo Piantanida, Andrej Virag, Marijan Kočevar, Gerhard Fritz, B. Alič, Anamaria Brozovic

مصطلحات موضوعية: Stereochemistry, Nitro compound, Antineoplastic Agents, Apoptosis, 1, 3-diaryltriazenes, synthesis, cytotoxicity, ROS induction, apoptosis, Chemical synthesis, Nitrophenols, chemistry.chemical_compound, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, Cytotoxic T cell, Humans, Prodrugs, Triazene, Cell Proliferation, Pharmacology, chemistry.chemical_classification, Chemistry, Organic Chemistry, Biological activity, General Medicine, DNA, Neoplasm, Prodrug, Endoplasmic Reticulum Stress, In vitro, Drug Resistance, Neoplasm, Nitro, Cisplatin, Triazenes, Reactive Oxygen Species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25d5f29b2cd986c44015550551840c7
https://doi.org/10.1016/j.ejmech.2011.04.024