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1
المؤلفون: Jane L. Grogan, Xin Yu, Allen Nguyen, Ganesh Kolumam, Eugene Chiang, Judy Young, Nathan Wei, Wai Lee Wong, Catherine Kung, Kristen Wolslegel, Laura DeForge, Michael J. Townsend
المصدر: Cytokine. 51:78-86
مصطلحات موضوعية: Male, T-Lymphocytes, medicine.medical_treatment, Immunology, Matrix metalloproteinase, Lymphocyte Activation, Biochemistry, Proinflammatory cytokine, Arthritis, Rheumatoid, Synovitis, Synovial Fluid, medicine, Humans, Immunology and Allergy, Synovial fluid, Molecular Biology, Aged, Demography, Aged, 80 and over, Chemistry, Lymphotoxin alpha1, beta2 Heterotrimer, Hematology, Fibroblasts, Middle Aged, medicine.disease, Cytokine, Lymphotoxin, Solubility, Rheumatoid arthritis, Metalloproteases, Female, Tumor necrosis factor alpha, Chemokines, Cell Adhesion Molecules
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2
المؤلفون: Ryan J. Watts, Wendy Sandoval, Yanmei Lu, Alexander W. Koch, Raymond K. Tong, Peter Liu, Lisa A Damico, Y. Gloria Meng, Wai Lee Wong, Hong Xiang
المصدر: mAbs. 1:364-369
مصطلحات موضوعية: medicine.medical_specialty, Angiogenesis, medicine.drug_class, Blotting, Western, Immunology, Enzyme-Linked Immunosorbent Assay, Monoclonal antibody, Mice, chemistry.chemical_compound, Western blot, Report, Cricetinae, Internal medicine, Neuropilin 1, medicine, Extracellular, Animals, Humans, Immunology and Allergy, Dose-Response Relationship, Drug, biology, medicine.diagnostic_test, Antibodies, Monoclonal, Neuropilin-1, Rats, Blot, Vascular endothelial growth factor, Endocrinology, Gene Expression Regulation, chemistry, biology.protein, Antibody
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3
المؤلفون: Kevin McDorman, Michelle Simpson, Eileen T. Duenas, Carl Ng, Amy Kim, Siao Ping Tsai, Jihong Yang, Richard Vandlen, Helga Raab, Paul Polakis, William Mallet, Viswanatham Katta, Richard H. Scheller, Sunil Bhakta, Mark S. Dennis, Suzanna Clark, Henry B. Lowman, Yvonne Chen, Wai Lee Wong, Jeffrey Gorrell, Chien C Lee, Y Gloria Meng, Jagath Reddy Junutula, Yanmei Lu, Douglas D. Leipold, Sylvia Weir, Sarajane Ross, Kelly Flagella, Susan D. Spencer, Mark X. Sliwkowski, Rayna Venook
المصدر: Nature Biotechnology. 26:925-932
مصطلحات موضوعية: Antibody-drug conjugate, Phage display, Antibodies, Neoplasm, Chemistry, Pharmaceutical, Biomedical Engineering, Antineoplastic Agents, Bioengineering, Pharmacology, Applied Microbiology and Biotechnology, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, Therapeutic index, Antigen, Antibody Specificity, In vivo, Cell Line, Tumor, Animals, Humans, Cysteine, Sulfhydryl Compounds, Ovarian Neoplasms, Binding Sites, biology, Cytotoxins, Immunotoxins, Antibodies, Monoclonal, Membrane Proteins, Rats, Macaca fascicularis, Monomethyl auristatin E, chemistry, Biochemistry, CA-125 Antigen, Mutagenesis, Site-Directed, biology.protein, Molecular Medicine, Female, Antibody, Oligopeptides, Biotechnology, Conjugate
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4
المؤلفون: Jeff Lutman, Allen Nguyen, Chae Janeka Reed, Zhihua Julia Qiu, Anan Chuntharapai, Judy Young, Jane L. Grogan, Xiaoying Gao, Laura DeForge, Rong Deng, Yong Ying, Wai Lee Wong
المصدر: Journal of immunological methods. 424
مصطلحات موضوعية: medicine.drug_class, medicine.medical_treatment, Immunology, Monoclonal antibody, Antibodies, Monoclonal, Humanized, Ligands, Sensitivity and Specificity, Epitope, In vivo, medicine, Immunology and Allergy, Animals, Humans, Lymphotoxin-alpha, Antibody-dependent cell-mediated cytotoxicity, Immunoassay, medicine.diagnostic_test, biology, Chemistry, Antibodies, Monoclonal, Reproducibility of Results, Molecular biology, In vitro, Antibodies, Anti-Idiotypic, Macaca fascicularis, Cytokine, biology.protein, Antibody
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5
المؤلفون: Yanmei Lu, Y. Gloria Meng, Wai Lee Wong
المصدر: Journal of Immunological Methods. 314:74-79
مصطلحات موضوعية: Luminescence, Recombinant Fusion Proteins, High-throughput screening, Immunology, Gene Dosage, Enzyme-Linked Immunosorbent Assay, CHO Cells, Humanized antibody, Mice, Antigen, Antibody Specificity, Cricetinae, Animals, Immunology and Allergy, Electrochemiluminescence, Centrifugation, Chromatography, biology, Chemistry, Chinese hamster ovary cell, Antibodies, Monoclonal, Antigens, CD20, Molecular biology, Clone Cells, Standard curve, biology.protein, Antibody
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6
المؤلفون: Ralph H. Schwall, Nazli Ghaboosi, Sharon Erickson, Zhi Ricky Quan, Jessica Kloss, David Finkle, Wai Lee Wong, Hartmut Koeppen, Vida Asghari, P Hollingshead, Elaine Mai
المصدر: Clinical Cancer Research. 10:2499-2511
مصطلحات موضوعية: Genetically modified mouse, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Time Factors, Receptor, ErbB-2, medicine.medical_treatment, Transgene, Molecular Sequence Data, Mammary gland, Down-Regulation, Enzyme-Linked Immunosorbent Assay, Mammary Neoplasms, Animal, Mice, Transgenic, Biology, Antibodies, Monoclonal, Humanized, Targeted therapy, Mice, Harderian gland, Breast cancer, Trastuzumab, Mammary tumor virus, Internal medicine, medicine, Animals, Humans, RNA, Messenger, Transgenes, Neoplasm Metastasis, Promoter Regions, Genetic, In Situ Hybridization, Fluorescence, Base Sequence, Models, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Antibodies, Monoclonal, Neoplasms, Experimental, medicine.disease, Immunohistochemistry, medicine.anatomical_structure, Endocrinology, Mammary Tumor Virus, Mouse, Oncology, Disease Progression, Cancer research, RNA, Female, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2508d33cc8e7d9856af78ebd7deb12
https://doi.org/10.1158/1078-0432.ccr-03-0448 -
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المؤلفون: Kerry Zobel, Wai Lee Wong, Sachdev S. Sidhu, Jian Ping Yin, Michael F. T. Koehler, Laurence A. Lasky, M. Theresa Pisabarro, Sherry Yeh, Nicholas J. Skelton
المصدر: Journal of Biological Chemistry. 278:7645-7654
مصطلحات موضوعية: Alanine, chemistry.chemical_classification, Mutation, Phage display, Mutagenesis, PDZ domain, Peptide, Cell Biology, Biology, medicine.disease_cause, Ligand (biochemistry), Biochemistry, chemistry, medicine, Biophysics, Binding site, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::143346cbd8141dae6a282d915194d24f
https://doi.org/10.1074/jbc.m209751200 -
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المؤلفون: Roberta Demott Friberg, Sherleen H. Huang, Ariel L. Barkan, P. Jean Ho, Neil Gesundheit, Wai Lee Wong
المصدر: Metabolism. 44:667-672
مصطلحات موضوعية: Adult, Male, Chronic exposure, medicine.medical_specialty, Calorie, Endocrinology, Diabetes and Metabolism, Endogeny, Biology, Cohort Studies, Eating, Endocrinology, Reference Values, Growth hormone-binding protein, Internal medicine, Acromegaly, medicine, Humans, Circadian rhythm, Aged, Analysis of Variance, Fasting, Middle Aged, medicine.disease, Growth Hormone, Female, Carrier Proteins, Quantitative analysis (chemistry), Federal state
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9
المؤلفون: M. Sadick, A. M. Boylan, J. M. Hoeffel, Wai Lee Wong, Anan Chuntharapai, K. T. Hartiala, V. C. Broaddus, Caroline Hebert
المصدر: American Journal of Physiology-Lung Cellular and Molecular Physiology. 267:L137-L144
مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Physiology, medicine.drug_class, Blotting, Western, Molecular Sequence Data, Monoclonal antibody, Pleural disease, Antigen, Desensitization (telecommunications), In vivo, Physiology (medical), medicine, Animals, Interleukin 8, Pleurisy, Lagomorpha, Base Sequence, Chemotactic Factors, biology, business.industry, Interleukin-8, Cell Biology, medicine.disease, biology.organism_classification, Molecular biology, Recombinant Proteins, Body Fluids, Endotoxins, Molecular Probes, Immunology, Pleura, Rabbits, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0398f0da2f7cc6129ac7460ff823bbd
https://doi.org/10.1152/ajplung.1994.267.2.l137 -
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المؤلفون: Helga Raab, Richard H. Scheller, Reina N. Fuji, Suzie J. Scales, Ola Saad, Darshana Ramesh Patel, Leslie A. Khawli, Willy Solis, Allen J. Ebens, Charles Eigenbrot, Dongwei Li, Janet Tien, Mark X. Sliwkowski, Elaine Mai, Luna Liu, Paul Polakis, Paul J. Mcdonald, Susan D. Spencer, Surinder Kaur, Shang-Fan Yu, Margaret Kenrick, Wai Lee Wong, Jay Tibbitts, Trung Nguyen, Philip E. Hass, Sunil Bhakta, Jakub Baudys, Richard Vandlen, Kelly Flagella, Jagath Reddy Junutula, Kathryn L Parsons-Reponte, Keyang Xu, Ben-Quan Shen
المصدر: Nature biotechnology. 30(2)
مصطلحات موضوعية: Models, Molecular, Immunoconjugates, Cell Survival, Protein Conformation, Biomedical Engineering, Mice, Nude, Bioengineering, Antibodies, Monoclonal, Humanized, Protein Engineering, Applied Microbiology and Biotechnology, Antibodies, Maleimides, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Succinimide, Cell Line, Tumor, Structure–activity relationship, Animals, Humans, Aminobenzoates, Maytansine, Cysteine, Sulfhydryl Compounds, Binding site, Maleimide, Mammary Neoplasms, Experimental, Glutathione, Trastuzumab, Rats, Macaca fascicularis, Biochemistry, chemistry, Immunoglobulin G, Biophysics, Molecular Medicine, Binding Sites, Antibody, Linker, Oligopeptides, Biotechnology, Conjugate