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1
المؤلفون: Chin-Chung Lin, Amin A. Nomeir, Ashit K. Ganguly, Patrick Pinto, Matthew Bryant, Ming Liu, F. G. Njoroge, Bancha Vibulbhan, Walter R. Bishop, Doll Ronald J, V. Girijavallabhan
المصدر: Journal of Medicinal Chemistry. 41:1561-1567
مصطلحات موضوعية: Farnesyl Protein Transferase, Pyridines, Stereochemistry, medicine.drug_class, Administration, Oral, Biological Availability, Mice, Nude, Antineoplastic Agents, Carboxamide, Oncogene Protein p21(ras), Cyclic N-Oxides, Mice, chemistry.chemical_compound, In vivo, Drug Discovery, Tumor Cells, Cultured, medicine, Animals, Humans, Enzyme Inhibitors, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, biology, Biological activity, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Female, Piperidine, Drug Screening Assays, Antitumor, Neoplasm Transplantation, Acetamide
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2
المؤلفون: Alan K. Mallams, Doll Ronald J, Shiyong Wang, Jesse Wong, Walter R. Bishop, Ashit K. Ganguly, F. G. Njoroge, Donna Carr, Linda James, Bancha Vibulbhan, Taveras Arthur G, Z. Li, C. Nardo, I. King, James J. Kaminski, Joanne M. Petrin, Paul Kirschmeier, V. Girijavallabhan, Stacy W. Remiszewski, Ming Liu, Carmen S. Alvarez, Randall R. Rossman, Chin-Chung Lin, Mathew S. Bryant, Mark E. Snow, Joseph J. Catino
المصدر: Bioorganic & Medicinal Chemistry. 5:93-99
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Farnesyl Protein Transferase, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Biochemistry, Mass Spectrometry, Mice, Piperidines, Prenylation, Drug Discovery, Tumor Cells, Cultured, Animals, Humans, Tumor growth, Molecular Biology, Antitumor activity, Tetrapeptide, Chemistry, Organic Chemistry, Benzazepines, Molecular Medicine, Signal transduction process, Intracellular
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3
المؤلفون: Joanne M. Petrin, F. G. Njoroge, Bancha Vibulbhan, Walter R. Bishop, Doll Ronald J, V. Girijavallabhan, Ashit K. Ganguly, Carmen S. Alvarez
المصدر: ChemInform. 28
مصطلحات موضوعية: chemistry.chemical_classification, chemistry, Farnesyl Protein Transferase, Stereochemistry, General Medicine, Sulfonamide, Tricyclic
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4
المؤلفون: Arthur King, Walter R. Bishop, E. Barrabee, Joseph Terracciano, Ronald Mierzwa, Min Chu, Robert Patton, M. S. Puar, M. Hallade, Mahesh Patel
المصدر: ChemInform. 29
مصطلحات موضوعية: Farnesyl Protein Transferase, biology, Chemistry, Stereochemistry, General Medicine, Fungus, biology.organism_classification
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5
المؤلفون: Walter R. Bishop, S. B. Rosenblum, Jay Weinstein, Joseph M. Kelly, Paul Kirschmeier, Michael Connolly, Linda James, Ronald L. Wolin, Adriano Afonso
المصدر: ChemInform. 30
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Farnesyl Protein Transferase, Stereochemistry, Amide, Benzoxepin, Pyridine, Biological activity, General Medicine, Ring (chemistry)
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6
المؤلفون: Nielsen Ll, Bryant Ms, Paul Kirschmeier, Ming Liu, Walter R. Bishop
مصطلحات موضوعية: Clinical trial, biology, In vivo, Farnesyltransferase, Transgene, biology.protein, Cytotoxic T cell, Farnesyl Transferase, Clinical efficacy, Pharmacology, Bioavailability
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4a6a6d51f1bb1c8545446ae1ba5c4e5c
https://doi.org/10.1016/s0076-6879(01)33065-3 -
7
المؤلفون: Pai Jk, Whyte D, Walter R. Bishop, Paul Kirschmeier, Wilson O
مصطلحات موضوعية: Gene isoform, Expression vector, biology, Biochemistry, Prenylation, Farnesyltransferase, biology.protein, Protein prenylation, Heterologous expression, Transfection, GTPase, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8b57c847ad8b973d66be1bdbd44ff2e4
https://doi.org/10.1016/s0076-6879(01)32196-1 -
8
المؤلفون: Kimberly Gray, Walter R. Bishop, Doll Ronald J, Lydia Armstrong, Donna Carr, Taveras Arthur G, Linda James, Paul Kirschmeier, Hena R. Ashar
المصدر: Chemical research in toxicology. 13(10)
مصطلحات موضوعية: Alkyl and Aryl Transferases, Chemistry, Farnesyl Transferase Inhibitor, Cell Cycle, Antineoplastic Agents, General Medicine, Toxicology, Mechanism of action, Biochemistry, medicine, Animals, Humans, medicine.symptom, Enzyme Inhibitors, Tumor Suppressor Protein p53
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9
المؤلفون: Matthew Bryant, Dell J, Ming Liu, Amin A. Nomeir, Bohdan Yaremko, Randall R. Rossman, Paul Kirschmeier, Doll Ronald J, Chin-Chung Lin, Walter A. Korfmacher, Joseph J. Catino, N. Prioli, M. Malkowski, Philip Lipari, Walter R. Bishop, V. Girijavallabhan, Z. Li, Alan K. Mallams, Jianping Chen, Suininhg Lee
المصدر: Cancer chemotherapy and pharmacology. 43(1)
مصطلحات موضوعية: Cancer Research, Farnesyl Protein Transferase, medicine.medical_treatment, Biological Availability, Mice, Nude, Antineoplastic Agents, Biology, Toxicology, Transfection, Piperazines, Cyclic N-Oxides, chemistry.chemical_compound, Mice, Prenylation, medicine, Animals, Humans, Pharmacology (medical), Enzyme Inhibitors, Cell Line, Transformed, Pharmacology, Farnesyl-diphosphate farnesyltransferase, Genes, mos, COS cells, Alkyl and Aryl Transferases, Oncogene, Growth factor, Fibroblasts, Molecular biology, Genes, ras, Oncology, chemistry, Biochemistry, Colonic Neoplasms, Signal transduction, Growth inhibition, Cell Division, Neoplasm Transplantation
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10
المؤلفون: Bohdan Yaremko, Ashit K. Ganguly, D. F. Rane, M. Malkowski, Robert Patton, Chin-Chung Lin, Walter R. Bishop, Bancha Vibulbhan, Jianping Chen, Amin A. Nomeir, Philip Lipari, Doll Ronald J, Matthew Bryant, Joanne M. Petrin, Chen Kj, Dell J, Ming Liu, Z. Li, F. G. Njoroge, Girijavallabhan, I. King, Suining Lee, Joseph J. Catino
المصدر: Journal of medicinal chemistry. 40(26)
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Farnesyl Protein Transferase, medicine.drug_class, Stereochemistry, Pyridines, Substituent, Protein Prenylation, Mice, Nude, Carboxamide, Antineoplastic Agents, Transfection, Chemical synthesis, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Piperidines, Drug Discovery, medicine, Structure–activity relationship, Phenyl group, Animals, Enzyme Inhibitors, Alkyl and Aryl Transferases, biology, Molecular Structure, 3T3 Cells, Neoplasms, Experimental, chemistry, Enzyme inhibitor, Drug Design, COS Cells, biology.protein, ras Proteins, Molecular Medicine, Piperidine