المؤلفون: Reardon HT; Abide Therapeutics, San Diego, CA, USA., Herbst RA; Abide Therapeutics, San Diego, CA, USA., Henry CL; Abide Therapeutics, San Diego, CA, USA., Herbst DM; Abide Therapeutics, San Diego, CA, USA., Ngo N; Abide Therapeutics, San Diego, CA, USA., Cisar JS; Abide Therapeutics, San Diego, CA, USA.; Janssen Research & Development, Spring House, PA., Weber OD; Abide Therapeutics, San Diego, CA, USA., Niphakis MJ; Abide Therapeutics, San Diego, CA, USA., O'Neill GP; Abide Therapeutics, San Diego, CA, USA.

المصدر: SLAS technology [SLAS Technol] 2019 Oct; Vol. 24 (5), pp. 489-498. Date of Electronic Publication: 2019 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-6311 (Electronic) Linking ISSN: 24726303 NLM ISO Abbreviation: SLAS Technol Subsets: MEDLINE

مواضيع طبية MeSH: Microfluidics/*methods , Proteomics/*methods, Algorithms ; Animals ; Biological Assay ; Mice ; Molecular Weight ; Reproducibility of Results

المؤلفون: Clapper JR; Abide Therapeutics, San Diego, California., Henry CL; Abide Therapeutics, San Diego, California., Niphakis MJ; Abide Therapeutics, San Diego, California., Knize AM; Abide Therapeutics, San Diego, California., Coppola AR; Abide Therapeutics, San Diego, California., Simon GM; Abide Therapeutics, San Diego, California., Ngo N; Abide Therapeutics, San Diego, California., Herbst RA; Abide Therapeutics, San Diego, California., Herbst DM; Abide Therapeutics, San Diego, California., Reed AW; Abide Therapeutics, San Diego, California., Cisar JS; Abide Therapeutics, San Diego, California., Weber OD; Abide Therapeutics, San Diego, California., Viader A; Abide Therapeutics, San Diego, California., Alexander JP; Abide Therapeutics, San Diego, California., Cunningham ML; Abide Therapeutics, San Diego, California., Jones TK; Abide Therapeutics, San Diego, California., Fraser IP; Abide Therapeutics, San Diego, California., Grice CA; Abide Therapeutics, San Diego, California., Ezekowitz RAB; Abide Therapeutics, San Diego, California., O'Neill GP; Abide Therapeutics, San Diego, California., Blankman JL; Abide Therapeutics, San Diego, California jackie@abidetx.com.

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2018 Dec; Vol. 367 (3), pp. 494-508. Date of Electronic Publication: 2018 Oct 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Endocannabinoids/*metabolism , Enzyme Inhibitors/*pharmacology , Monoacylglycerol Lipases/*antagonists & inhibitors, Analgesics/pharmacology ; Animals ; Antipruritics/pharmacology ; Arachidonic Acids/metabolism ; Brain/drug effects ; Brain/metabolism ; Cell Line, Tumor ; Cyclooxygenase Inhibitors/pharmacology ; Glycerides/metabolism ; Humans ; Hydrolysis/drug effects ; Male ; Mice ; Mice, Inbred ICR ; PC-3 Cells ; Pain/drug therapy ; Pain/metabolism ; Piperidines/pharmacology ; Prostaglandins/pharmacology ; Rats ; Rats, Sprague-Dawley ; Rodentia

المؤلفون: Cisar JS; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Weber OD; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Clapper JR; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Blankman JL; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Henry CL; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Simon GM; Vividion Therapeutics , 3565 General Atomics Court, Suite 100 , San Diego , California 92121 , United States., Alexander JP; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Jones TK; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Ezekowitz RAB; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., O'Neill GP; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States., Grice CA; Abide Therapeutics , 10835 Road to the Cure, Suite 250 , San Diego , California 92121 , United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2018 Oct 25; Vol. 61 (20), pp. 9062-9084. Date of Electronic Publication: 2018 Aug 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Discovery*, Monoacylglycerol Lipases/*antagonists & inhibitors , Nervous System Diseases/*drug therapy , Nervous System Diseases/*enzymology , Piperazine/*pharmacology , Piperazines/*pharmacology , Pyrrolidines/*pharmacology, Animals ; Dogs ; Dose-Response Relationship, Drug ; Humans ; Male ; Mice ; Molecular Targeted Therapy ; Pain/drug therapy ; Pain/enzymology ; Piperazine/pharmacokinetics ; Piperazine/therapeutic use ; Piperazines/pharmacokinetics ; Piperazines/therapeutic use ; Pyrrolidines/pharmacokinetics ; Pyrrolidines/therapeutic use ; Rats ; Tissue Distribution