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المصدر: British Journal of Pharmacology. 159:449-461
مصطلحات موضوعية: Pharmacology, Chemistry, Protein subunit, Glutamate receptor, Excitotoxicity, medicine.disease_cause, Neuroprotection, chemistry.chemical_compound, Biochemistry, Ifenprodil, medicine, Binding site, Receptor, Binding domain
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2دورية أكاديمية
المؤلفون: Wee XK; Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore., Yang T, Go ML
المصدر: ChemMedChem [ChemMedChem] 2012 May; Vol. 7 (5), pp. 777-91. Date of Electronic Publication: 2012 Mar 13.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Agents/*chemical synthesis, Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; Humans ; Indoles/chemical synthesis ; Indoles/chemistry ; Indoles/pharmacology ; Inhibitory Concentration 50 ; K562 Cells ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Molecular Structure ; Solubility ; Structure-Activity Relationship ; Transplantation, Heterologous
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3دورية أكاديمية
المؤلفون: Wee XK; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Republic of Singapore., Ng KS, Leung HW, Cheong YP, Kong KH, Ng FM, Soh W, Lam Y, Low CM
المصدر: British journal of pharmacology [Br J Pharmacol] 2010 Jan 01; Vol. 159 (2), pp. 449-61. Date of Electronic Publication: 2010 Jan 15.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
مواضيع طبية MeSH: Benzimidazoles/*pharmacology , Neurons/*drug effects , Neuroprotective Agents/*pharmacology , Receptors, N-Methyl-D-Aspartate/*metabolism , Sulfonamides/*pharmacology, Animals ; Binding Sites ; Cells, Cultured ; Cerebral Cortex/cytology ; Embryo, Mammalian ; Hydrogen-Ion Concentration ; N-Methylaspartate/pharmacology ; Neurons/metabolism ; Protein Structure, Tertiary ; Protein Subunits/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/agonists ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors
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4دورية أكاديمية
المؤلفون: Wee XK; Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore., Yeo WK, Zhang B, Tan VB, Lim KM, Tay TE, Go ML
المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2009 Nov 01; Vol. 17 (21), pp. 7562-71. Date of Electronic Publication: 2009 Sep 11.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Agents/*chemical synthesis , Indoles/*chemical synthesis, Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Computer Simulation ; Cyclin-Dependent Kinase 2/antagonists & inhibitors ; Cyclin-Dependent Kinase 2/metabolism ; Drug Screening Assays, Antitumor ; Humans ; Indoles/chemistry ; Indoles/pharmacology ; K562 Cells ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/pharmacology ; Structure-Activity Relationship