المؤلفون: Guerriero CJ; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: cjg11@pitt.edu., Gomez YK; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California., Daskivich GJ; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania., Reutter KR; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania., Augustine AA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania., Weiberth KF; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania., Nakatsukasa K; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania; Division of Biological Science, Graduate School of Natural Sciences, Nagoya City University, Nagoya, Aichi, Japan., Grabe M; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California., Brodsky JL; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.

المصدر: Biophysical journal [Biophys J] 2019 Aug 20; Vol. 117 (4), pp. 668-678. Date of Electronic Publication: 2019 Jul 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Dynamics Simulation*, ATP-Binding Cassette Transporters/*chemistry , Cell Membrane/*chemistry , Saccharomyces cerevisiae Proteins/*chemistry, ATP-Binding Cassette Transporters/metabolism ; Cell Membrane/metabolism ; Protein Domains ; Protein Folding ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae Proteins/metabolism

المؤلفون: Guerriero CJ; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Reutter KR; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Augustine AA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Preston GM; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Weiberth KF; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Mackie TD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Cleveland-Rubeor HC; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Bethel NP; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158., Callenberg KM; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Nakatsukasa K; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260.; Division of Biological Science, Graduate School of Natural Sciences, Nagoya City University, Nagoya, Aichi 467-8501, Japan., Grabe M; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158., Brodsky JL; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260 jbrodsky@pitt.edu.

المصدر: Molecular biology of the cell [Mol Biol Cell] 2017 Jul 15; Vol. 28 (15), pp. 2076-2090. Date of Electronic Publication: 2017 May 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum-Associated Degradation/*physiology , Membrane Proteins/*metabolism, Adenosine Triphosphatases/metabolism ; Cell Cycle Proteins/metabolism ; Endoplasmic Reticulum/metabolism ; Hydrophobic and Hydrophilic Interactions ; Membranes/metabolism ; Mutation ; Proteasome Endopeptidase Complex/metabolism ; Protein Folding ; Protein Translocation Systems/metabolism ; Protein Transport ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Ubiquitin/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitination

المؤلفون: Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S

المصدر: The Journal of clinical investigation [J Clin Invest] 2016 Sep 01; Vol. 126 (9), pp. 3585-97. Date of Electronic Publication: 2016 Aug 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Huntingtin Protein/*genetics , Huntington Disease/*genetics , Serine/*chemistry, Alanine/chemistry ; Animals ; Aspartic Acid/chemistry ; Behavior, Animal ; Chromosomes, Artificial, Bacterial ; Disease Models, Animal ; Disease Progression ; Female ; Gait ; Genotype ; Humans ; Huntingtin Protein/chemistry ; Male ; Maze Learning ; Mice ; Mice, Transgenic ; Mutation ; Nerve Tissue Proteins/genetics ; Neurodegenerative Diseases/metabolism ; Neurons/metabolism ; Nuclear Proteins/genetics ; Phenotype ; Phosphorylation ; Proteasome Endopeptidase Complex/metabolism

المؤلفون: Ghosh R; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA., Wang L; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA., Wang ES; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA., Perera BG; Department of Chemistry, University of Washington, Seattle, WA 98195, USA., Igbaria A; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA., Morita S; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA., Prado K; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA., Thamsen M; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA., Caswell D; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA., Macias H; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA., Weiberth KF; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA., Gliedt MJ; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA., Alavi MV; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA 94143, USA., Hari SB; Department of Chemistry, University of Washington, Seattle, WA 98195, USA., Mitra AK; Department of Chemistry, University of Washington, Seattle, WA 98195, USA., Bhhatarai B; Department of Molecular and Cellular Pharmacology,, Miller School of Medicine, University of Miami, FL 33136, USA., Schürer SC; Center for Computational Science, Miller School of Medicine, University of Miami, FL 33136, USA; Department of Molecular and Cellular Pharmacology,, Miller School of Medicine, University of Miami, FL 33136, USA., Snapp EL; Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA., Gould DB; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA., German MS; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA., Backes BJ; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA., Maly DJ; Department of Chemistry, University of Washington, Seattle, WA 98195, USA., Oakes SA; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: scott.oakes@ucsf.edu., Papa FR; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Lung Biology Center, University of California, San Francisco, San Francisco, CA 94143, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: frpapa@medicine.ucsf.edu.

المصدر: Cell [Cell] 2014 Jul 31; Vol. 158 (3), pp. 534-48. Date of Electronic Publication: 2014 Jul 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum Stress*, Endoribonucleases/*antagonists & inhibitors , Protein Kinase Inhibitors/*pharmacology , Protein Serine-Threonine Kinases/*antagonists & inhibitors, Allosteric Regulation ; Animals ; Apoptosis/drug effects ; Cell Line ; Endoribonucleases/chemistry ; Endoribonucleases/metabolism ; Enzyme Activation/drug effects ; Humans ; Islets of Langerhans/metabolism ; Male ; Mice ; Protein Serine-Threonine Kinases/chemistry ; Protein Serine-Threonine Kinases/metabolism ; Rats ; Retina/metabolism ; Ribonucleases/antagonists & inhibitors

المؤلفون: Guerriero CJ; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA., Weiberth KF, Brodsky JL

المصدر: The Journal of biological chemistry [J Biol Chem] 2013 Jun 21; Vol. 288 (25), pp. 18506-20. Date of Electronic Publication: 2013 May 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cytoplasm/*metabolism , HSP70 Heat-Shock Proteins/*metabolism , Saccharomyces cerevisiae/*metabolism , Saccharomyces cerevisiae Proteins/*metabolism , Ubiquitin-Protein Ligases/*metabolism, ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/metabolism ; Active Transport, Cell Nucleus ; Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Binding Sites/genetics ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Nucleus/metabolism ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum-Associated Degradation ; HSP70 Heat-Shock Proteins/genetics ; Immunoblotting ; Microscopy, Fluorescence ; Mutation ; Proteasome Endopeptidase Complex/metabolism ; Protein Binding ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Substrate Specificity ; Ubiquitin/genetics ; Ubiquitin/metabolism ; Ubiquitin-Protein Ligases/genetics ; Valosin Containing Protein

المؤلفون: Judy ME; Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America ; Department of Biochemistry, University of California San Francisco, San Francisco, California, United States of America., Nakamura A, Huang A, Grant H, McCurdy H, Weiberth KF, Gao F, Coppola G, Kenyon C, Kao AW

المصدر: PLoS genetics [PLoS Genet] 2013; Vol. 9 (9), pp. e1003714. Date of Electronic Publication: 2013 Sep 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Osmotic Pressure*, Apoptosis/*genetics , Endoplasmic Reticulum/*genetics , Stress, Physiological/*genetics, Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans/physiology ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Caspases/genetics ; Caspases/metabolism ; Endoplasmic Reticulum/metabolism ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mutation ; Signal Transduction/genetics