لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Nishimura Y; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892., Francis JN; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112.; Navigen, Inc., Salt Lake City, UT 84108., Donau OK; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892., Jesteadt E; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892., Sadjadpour R; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892., Smith AR; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112., Seaman MS; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02215., Welch BD; Navigen, Inc., Salt Lake City, UT 84108., Martin MA; Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892; malm@nih.gov kay@biochem.utah.edu., Kay MS; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112; malm@nih.gov kay@biochem.utah.edu.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 08; Vol. 117 (36), pp. 22436-22442. Date of Electronic Publication: 2020 Aug 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents*/chemistry , Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/therapeutic use , HIV*/drug effects , HIV*/genetics , HIV Infections*/drug therapy , HIV Infections*/prevention & control , HIV Infections*/virology , Simian Immunodeficiency Virus*/drug effects , Simian Immunodeficiency Virus*/genetics, Virus Internalization/*drug effects, Animals ; Drug Evaluation, Preclinical ; Female ; HIV Envelope Protein gp41/antagonists & inhibitors ; Macaca mulatta ; Male

المؤلفون: Redman JS; Department of Biochemistry , University of Utah School of Medicine , Salt Lake City , Utah 84132 , United States., Francis JN; Department of Biochemistry , University of Utah School of Medicine , Salt Lake City , Utah 84132 , United States.; Navigen Inc. , Salt Lake City , Utah 84108 , United States., Marquardt R; Department of Biochemistry , University of Utah School of Medicine , Salt Lake City , Utah 84132 , United States., Papac D; Navigen Inc. , Salt Lake City , Utah 84108 , United States., Mueller AL; Navigen Inc. , Salt Lake City , Utah 84108 , United States., Eckert DM; Department of Biochemistry , University of Utah School of Medicine , Salt Lake City , Utah 84132 , United States., Welch BD; Navigen Inc. , Salt Lake City , Utah 84108 , United States., Kay MS; Department of Biochemistry , University of Utah School of Medicine , Salt Lake City , Utah 84132 , United States.

المصدر: Molecular pharmaceutics [Mol Pharm] 2018 Mar 05; Vol. 15 (3), pp. 1169-1179. Date of Electronic Publication: 2018 Feb 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: HIV Fusion Inhibitors/*pharmacokinetics , HIV Infections/*drug therapy , HIV-1/*drug effects , Peptide Fragments/*pharmacokinetics, Animals ; Cholesterol/chemistry ; Delayed-Action Preparations ; Drug Carriers/chemistry ; Drug Design ; Drug Evaluation, Preclinical ; HIV Fusion Inhibitors/administration & dosage ; HIV Fusion Inhibitors/chemical synthesis ; HIV Infections/prevention & control ; HIV Infections/virology ; HIV-1/physiology ; Half-Life ; Macaca fascicularis ; Male ; Models, Animal ; Peptide Fragments/administration & dosage ; Peptide Fragments/chemical synthesis ; Rats ; Rats, Sprague-Dawley ; Stereoisomerism

المؤلفون: Clinton TR; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah, 84112-5650., Weinstock MT, Jacobsen MT, Szabo-Fresnais N, Pandya MJ, Whitby FG, Herbert AS, Prugar LI, McKinnon R, Hill CP, Welch BD, Dye JM, Eckert DM, Kay MS

المصدر: Protein science : a publication of the Protein Society [Protein Sci] 2015 Apr; Vol. 24 (4), pp. 446-63. Date of Electronic Publication: 2014 Oct 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-896X (Electronic) Linking ISSN: 09618368 NLM ISO Abbreviation: Protein Sci Subsets: MEDLINE

مواضيع طبية MeSH: Ebolavirus/*chemistry , Viral Envelope Proteins/*chemistry , Viral Envelope Proteins/*metabolism, Amino Acid Sequence ; Drug Delivery Systems ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Sequence Alignment ; Viral Envelope Proteins/genetics

المؤلفون: Poor TA; Department of Molecular Biosciences Northwestern University, Evanston, Illinois, USA., Song AS; Department of Molecular Biosciences Northwestern University, Evanston, Illinois, USA., Welch BD; Department of Molecular Biosciences Northwestern University, Evanston, Illinois, USA Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, USA., Kors CA; Department of Molecular Biosciences Northwestern University, Evanston, Illinois, USA Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, USA., Jardetzky TS; Department of Structural Biology, Stanford University, Stanford, California, USA., Lamb RA; Department of Molecular Biosciences Northwestern University, Evanston, Illinois, USA Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, USA ralamb@northwestern.edu.

المصدر: Journal of virology [J Virol] 2015 Mar; Vol. 89 (6), pp. 3438-41. Date of Electronic Publication: 2015 Jan 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

مواضيع طبية MeSH: Parainfluenza Virus 5/*metabolism , Viral Fusion Proteins/*chemistry, Amino Acid Motifs ; Crystallography, X-Ray ; Humans ; Mutation ; Parainfluenza Virus 5/chemistry ; Parainfluenza Virus 5/genetics ; Protein Stability ; Protein Structure, Tertiary ; Rubulavirus Infections/virology ; Viral Fusion Proteins/genetics ; Viral Fusion Proteins/metabolism