المؤلفون: Cao, Yu, Axup, Jun Y, Y., Jennifer S, Wang, Rongsheng E, Choi, Seihyun, Tardif, Virginie, Lim, Reyna KV, Pugh, Holly M, Lawson, Brian R, Welzel, Gus, Kazane, Stephanie A, Sun, Ying, Tian, Feng, Srinagesh, Shailaja, Javahishvili, Tsotne, Schultz, Peter G, Kim, Chan Hyuk

المصدر: Angewandte Chemie International Edition. 54(24)

مصطلحات موضوعية: Cancer, Breast Cancer, 5.2 Cellular and gene therapies, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, Aetiology, Animals, Antibodies, Bispecific, Breast Neoplasms, CD3 Complex, Cell Line, Tumor, Female, Humans, Jurkat Cells, Leukocytes, Mononuclear, Mice, Receptor, ErbB-2, Receptors, Fc, T-Lymphocytes, Trastuzumab, Xenograft Model Antitumor Assays, Receptor, erbB-2, T-cell activation, antibody drug conjugates, bispecific antibodies, breast cancers, noncanonical amino acids, Chemical Sciences, Organic Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5zp2x39k

المؤلفون: Yang, Peng-Yu, Zou, Huafei, Chao, Elizabeth, Sherwood, Lance, Nunez, Vanessa, Keeney, Michael, Ghartey-Tagoe, Esi, Ding, Zhongli, Quirino, Herlinda, Luo, Xiaozhou, Welzel, Gus, Chen, Guohua, Singh, Parminder, Woods, Ashley K., Schultz, Peter G., Shen, Weijun

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2016 Apr 01. 113(15), 4140-4145.

URL الوصول: https://www.jstor.org/stable/26469270

المؤلفون: Constantinides, Panayiotis P., Welzel, Gus, Ellens, Harma, Smith, Philip L., Sturgis, Sandra, Yiv, Seang H., Owen, Albert B.

المصدر: Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. February 1996 13(2):210-215

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المؤلفون: Peng-Yu Yang, Huafei Zou, Chao, Elizabeth, Sherwood, Lance, Nunez, Vanessa, Keeney, Michael, Ghartey-Tagoe, Esi, Zhongli Ding, Quirino, Herlinda, Xiaozhou Luo, Welzel, Gus, Guohua Chen, Singh, Parminder, Woods, Ashley K., Schultz, Peter G., Weijun Shen

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 4/12/2016, Vol. 113 Issue 15, p4140-4145, 6p

مصطلحات موضوعية: EXENDINS, TRANSDERMAL medication, GLUCAGON-like peptide-1 agonists, GLUCAGON-like peptide-1 receptor, PHARMACOKINETICS, PHARMACODYNAMICS

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المؤلفون: Walker, John R., Pacoma, Reynand, Watson, James, Weijia Ou, Alves, Juliano, Mason, Daniel E., Peters, Eric C., Urbina, Hugo D., Welzel, Gus, Althage, Alana, Bo Liu, Tuntland, Tove, Jacobson, Laura H., Harris, Jennifer L., Schumacher, Andrew M.

المصدر: Journal of Neuroscience; 2/6/2013, Vol. 33 Issue 6, p2457-2464, 8p

مصطلحات موضوعية: PROTEOLYSIS, BLOOD plasma, NEPRILYSIN, DRUG dosage, BRAIN stimulation, LABORATORY mice, ALZHEIMER'S disease

المؤلفون: Cao Y; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Axup JY; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Ma JS; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Wang RE; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Choi S; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Tardif V; Department of Immunology and Microbial Science, The Scripps Research Institute (USA)., Lim RK; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Pugh HM; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Lawson BR; Department of Immunology and Microbial Science, The Scripps Research Institute (USA)., Welzel G; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Kazane SA; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Sun Y; EuCode Technology, Ambrx, Inc. 10975 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Tian F; EuCode Technology, Ambrx, Inc. 10975 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Srinagesh S; EuCode Technology, Ambrx, Inc. 10975 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Javahishvili T; EuCode Technology, Ambrx, Inc. 10975 N Torrey Pines Rd, La Jolla, CA 92037 (USA)., Schultz PG; Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037 (USA). Schultz@scripps.edu.; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, CA 92037 (USA). Schultz@scripps.edu., Kim CH; California Institute for Biomedical Research, 11119 N Torrey Pines Rd, La Jolla, CA 92037 (USA). chkim@calibr.org.

المصدر: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2015 Jun 08; Vol. 54 (24), pp. 7022-7. Date of Electronic Publication: 2015 Apr 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Bispecific/*chemistry , T-Lymphocytes/*metabolism, Animals ; Antibodies, Bispecific/immunology ; Antibodies, Bispecific/therapeutic use ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; CD3 Complex/immunology ; Cell Line, Tumor ; Female ; Humans ; Jurkat Cells ; Leukocytes, Mononuclear/immunology ; Mice ; Receptor, ErbB-2/immunology ; Receptors, Fc/chemistry ; Receptors, Fc/metabolism ; T-Lymphocytes/immunology ; Trastuzumab/chemistry ; Trastuzumab/immunology ; Xenograft Model Antitumor Assays