-
1دورية أكاديمية
المؤلفون: Dahlia M. Kenawy, Yifan Zhang, Moataz Elsisy, Youngjae Chun, Marlene I. Garcia-Neuer, Mahmoud Abdel-Rasoul, William C. Clark, Bryan W. Tillman
المصدر: JVS - Vascular Science, Vol 3, Iss , Pp 415-416 (2022)
مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
-
2
-
3
-
4
المؤلفون: Robin M. Shaw, Karen H. Vousden, Timothy J. Humpton, Thomas G. Bird, William C. Clark, Ann Hedley, Christos Kiourtis, Holly Hall, Colin Nixon, Karen Blyth
المصدر: Humpton, T J, Hall, H, Kiourtis, C, Nixon, C, Clark, W, Hedley, A, Shaw, R, Bird, T G, Blyth, K & Vousden, K H 2021, ' p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4 ', Cell Death and Differentiation . https://doi.org/10.1038/s41418-021-00871-3
مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, biology, Hepatotoxin, Cytochrome P450, Cell Biology, Liver regeneration, 3. Good health, law.invention, Cell biology, Signalling & Oncogenes, 03 medical and health sciences, Metabolism, 0302 clinical medicine, Mediator, chemistry, law, 030220 oncology & carcinogenesis, biology.protein, Suppressor, Liver function, Molecular Biology, Transcription factor, 030304 developmental biology
وصف الملف: application/pdf
-
5
المؤلفون: Sara Zanivan, Rafael S. Martinez, William C. Clark, Paul Peixoto, Sergio Lilla, Colin Nixon, Laura C. A. Galbraith, Eric Hervouet, Ladan Fazli, Ann Hedley, Sonia H.Y. Kung, Luke Gaughan, Linda K. Rushworth, Hing Y. Leung, Martin E. Gleave, Gillian M. Mackay, Chara Ntala, Mark Salji, David Sumpton, Arnaud Blomme, Giovanny Rodriguez Blanco, Elodie Renaude
المصدر: Cancer Research. 81:3664-3678
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Proteome, Mice, Nude, Apoptosis, Cell Cycle Proteins, mTORC1, Mechanistic Target of Rapamycin Complex 1, urologic and male genital diseases, Large Neutral Amino Acid-Transporter 1, Mice, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, In vivo, Biomarkers, Tumor, Tumor Cells, Cultured, Animals, Humans, Medicine, PI3K/AKT/mTOR pathway, Cell Proliferation, business.industry, TOR Serine-Threonine Kinases, ATF4, Transporter, Prognosis, medicine.disease, Activating Transcription Factor 4, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, Survival Rate, Androgen receptor, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Metabolome, Cancer research, Transcriptome, business, Intracellular
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349939edf7b5e75f161508418fa75fa8
https://doi.org/10.1158/0008-5472.can-20-3694 -
6E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
المؤلفون: Danny T. Huang, David Sumpton, Sergio Lilla, Lori Buetow, Syed Feroj Ahmed, William C. Clark, Gary J. Sibbet, Ann Hedley, Sara Zanivan, Mads Gabrielsen
المصدر: Oncogene
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lymphoma, B-Cell, Ubiquitylation, Endosome, Receptor Protein-Tyrosine Kinases, Mutant, Breast Neoplasms, macromolecular substances, Biology, medicine.disease_cause, environment and public health, Interactome, Article, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, hemic and lymphatic diseases, Genetics, medicine, Humans, Proto-Oncogene Proteins c-cbl, Molecular Biology, Adaptor Proteins, Signal Transducing, Cell Proliferation, Myeloproliferative Disorders, Ubiquitin, fungi, Cancer, Oncogenes, medicine.disease, Ubiquitin ligase, ErbB Receptors, Gene Expression Regulation, Neoplastic, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Tissue Array Analysis, 030220 oncology & carcinogenesis, Mutation, Proteolysis, biology.protein, Cancer research, Female, Carcinogenesis, Protein Binding
وصف الملف: application/pdf
-
7
المؤلفون: Owen J. Sansom, John R. P. Knight, Simon T. Barry, Rachel A. Ridgway, David Sumpton, Rory T. Steven, Giovanny Rodriguez-Blanco, Eyal Gottlieb, Gaurav Malviya, William C. Clark, Douglas Strathdee, Emma R. Johnson, Holly Hall, Alex Dexter, Teresa Murta, David Y. Lewis, Saverio Tardito, Gregory Hamm, Gavin Brown, Colin Nixon, Kathryn Gilroy, Zoltan Takats, Sudhir B Malla, Dmitry Solovyev, Sigrid K. Fey, Fatih Ceteci, Gillian M. Mackay, Susan E. Critchlow, Ann Hedley, Nikola Vlahov, Alan M. Race, Martin Bushell, Andrew D. Campbell, Arafath Kaja Najumudeen, Richard J. A. Goodwin, Josephine Bunch, Chelsea J. Nikula, Agata Mrowinska, Philip D Dunne, Rene Jackstadt, Joshua D.G. Leach
المصدر: Nature Genetics. 53:16-26
مصطلحات موضوعية: 0303 health sciences, Mutation, Mutant, mTORC1, Biology, medicine.disease_cause, digestive system diseases, Glutamine, 03 medical and health sciences, 0302 clinical medicine, Cancer cell, Genetics, medicine, Cancer research, Amino acid transporter, KRAS, Signal transduction, neoplasms, 030217 neurology & neurosurgery, 030304 developmental biology
-
8
المؤلفون: William C. Clark, Alicia G. Harley
المصدر: Annual Review of Environment and Resources. 45:331-386
مصطلحات موضوعية: Sustainable development, 010504 meteorology & atmospheric sciences, Political science, Corporate governance, Equity (finance), Sustainability science, Engineering ethics, 010501 environmental sciences, Construct (philosophy), Adaptation (computer science), 01 natural sciences, 0105 earth and related environmental sciences, General Environmental Science
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a7f16e49400beefd03aefe55c45b03cf
https://doi.org/10.1146/annurev-environ-012420-043621 -
9
المؤلفون: Pam Epler, Matt O'Nesti, William C. Clark
المصدر: Advising Preservice Teachers Through Narratives From Students With Disabilities ISBN: 9781799873594
Advising Preservice Teachers Through Narratives From Students With Disabilitiesمصطلحات موضوعية: media_common.quotation_subject, Support system, Empathy, Psychology, Social psychology, media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b80ee51df7ee0aec6570520430e10d39
https://doi.org/10.4018/978-1-7998-7359-4.ch008 -
10
المؤلفون: Jim Cassidy, Owen J. Sansom, William C. Clark, Luis Serrano, Volker M. Stucke, Martin J Drysdale, Martin R Turner, Arafath Kaja Najumudeen, R.P. Fordham, Karen Pickering, Lucas B. Zeiger, Ewan J. McGhee, Saskia M. Brachmann, Ann Hedley, Andrew D. Campbell, Kathryn Gilroy, Jeanette A. Johansson, Maureen M. Bain, David F. Vincent, Kevin Myant, Christina Kiel, Kurt I. Anderson, Benjamin LeRoy Miller, Angeliki Malliri, S.R. van Hoof, Sigrid K. Fey, Jan Paul Medema, E.B. Unal, Anna-Karin E. Johnsson, Catherine Nixon, Laura M. Machesky, Douglas Strathdee
المساهمون: Center of Experimental and Molecular Medicine, Radiotherapy, CCA - Cancer biology and immunology, Najumudeen, AK [0000-0002-3764-5721], Zeiger, LB [0000-0002-8712-3112], Gay, DM [0000-0002-7407-1245], Machesky, LM [0000-0002-7592-9856], Nixon, C [0000-0002-8085-2160], Johnsson, AE [0000-0002-0018-700X], Strathdee, D [0000-0003-2959-4327], Anderson, KI [0000-0002-9324-9598], Malliri, A [0000-0001-6848-090X], Turner, M [0000-0002-3801-9896], Serrano, L [0000-0002-5276-1392], Myant, K [0000-0001-8017-1093], Campbell, AD [0000-0003-3930-1276], Sansom, OJ [0000-0001-9540-3010], Apollo - University of Cambridge Repository, Najumudeen, A. K. [0000-0002-3764-5721], Zeiger, L. B. [0000-0002-8712-3112], Gay, D. M. [0000-0002-7407-1245], Machesky, L. M. [0000-0002-7592-9856], Nixon, C. [0000-0002-8085-2160], Johnsson, A. E. [0000-0002-0018-700X], Strathdee, D. [0000-0003-2959-4327], Anderson, K. I. [0000-0002-9324-9598], Malliri, A. [0000-0001-6848-090X], Turner, M. [0000-0002-3801-9896], Serrano, L. [0000-0002-5276-1392], Myant, K. [0000-0001-8017-1093], Campbell, A. D. [0000-0003-3930-1276], Sansom, O. J. [0000-0001-9540-3010]
المصدر: Nature communications, 12(1):56. Nature Publishing Group
Nature Communications
Pickering, KA, Gilroy, K, Cassidy, JW, Fey, SK, Najumudeen, AK, Zeiger, LB, Vincent, DF, Gay, DM, Johansson, J, Fordham, RP, Miller, B, Clark, W, Hedley, A, Unal, EB, Kiel, C, McGhee, E, Macheskey, LM, Nixon, C, Johnsson, AE, Bain, M, Strathdee, D, van Hoof, SR, Medema, JP, Anderson, KI, Brachmann, SM, Stucke, VM, Malliri, A, Drysdale, M, Turner, M, Serrano, L, Myant, K B, Campbell, AD & Sansom, OJ 2021, ' A RAC-GEF network critical for early intestinal tumourigenesis ', Nature Communications . https://doi.org/10.1038/s41467-020-20255-4
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
University of Edinburgh-PUREمصطلحات موضوعية: 0301 basic medicine, VAV3, rac1 GTP-Binding Protein, VAV2, Carcinogenesis, Homeòstasi, General Physics and Astronomy, Imaging, 0302 clinical medicine, Guanine Nucleotide Exchange Factors, Homeostasis, T-Lymphoma Invasion and Metastasis-inducing Protein 1, Wnt Signaling Pathway, Mice, Knockout, Multidisciplinary, Wnt signaling pathway, article, Phenotype, Up-Regulation, Colon cancer, Intestines, Organ Specificity, 030220 oncology & carcinogenesis, 64/60, Signal transduction, 631/67/70, Signal Transduction, Science, Adenomatous Polyposis Coli Protein, RAC1, 13/106, 631/67/1504/1885/1393, Biology, General Biochemistry, Genetics and Molecular Biology, 38/91, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Downregulation and upregulation, 14/33, Animals, Proto-Oncogene Proteins c-vav, Cancer models, Tumors, General Chemistry, 030104 developmental biology, Mutation, 13/51, Cancer research, Intestins -- Càncer, Genètica
وصف الملف: application/pdf; text/xml; application/zip
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a4588ea791829c408931197ab3e425
https://pure.amc.nl/en/publications/a-racgef-network-critical-for-early-intestinal-tumourigenesis(1d3b7cc2-5483-46a6-accd-e659022a288b).html