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1
المؤلفون: William F. Hodnick, Luis Llamas, Thomas C. Dent, Jianping Song, Youssef L. Bennani, Michael J. Robarge, John J. Harrington, Alain Stricker-Krongrad, Kurt R. Brunden, Bayard Huck, Chris Crumrine
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:4130-4134
مصطلحات موضوعية: Agonist, Nitrogen, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Structure-Activity Relationship, Dogs, Drug Discovery, medicine, Animals, Structure–activity relationship, Receptor, Molecular Biology, G protein-coupled receptor, chemistry.chemical_classification, Organic Chemistry, Biological activity, Feeding Behavior, Rats, Serotonin Receptor Agonists, chemistry, Drug Design, Molecular Medicine, 5-HT2C receptor agonist, Serotonin 5-HT2 Receptor Agonists, Half-Life, Tricyclic
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2
المؤلفون: Luis Llamas, William F. Hodnick, Michael J. Robarge, Bayard Huck, Chris Crumrine, Youssef L. Bennani, John J. Harrington, Thomas C. Dent, Alain Stricker-Krongrad, Kurt R. Brunden, Jianping Song
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:2891-2894
مصطلحات موضوعية: Agonist, Pyrimidine, medicine.drug_class, media_common.quotation_subject, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Bridged Bicyclo Compounds, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Receptor, Serotonin, 5-HT2C, medicine, Animals, Amines, Receptor, Molecular Biology, media_common, Octane, Aza Compounds, Molecular Structure, Organic Chemistry, Stereoisomerism, Appetite, Small molecule, Rats, 5-HT2C receptor, Pyrimidines, chemistry, Molecular Medicine, Serotonin 5-HT2 Receptor Agonists
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3
المؤلفون: Philip G. Penketh, David H. Sherman, William F. Hodnick, Krishnamurthy Shyam, Michael F. Belcourt, Alan C. Sartorelli
المصدر: Journal of Biological Chemistry. 276:34445-34452
مصطلحات موضوعية: chemistry.chemical_classification, biology, Hydroquinone, Stereochemistry, Crosslinking of DNA, DNA repair, Mitomycin, Kinetics, Mitomycin C, Borohydrides, DNA, Cell Biology, Biochemistry, Hydroquinones, chemistry.chemical_compound, Enzyme, Peroxidases, chemistry, biology.protein, Oxidation-Reduction, Molecular Biology, Chromatography, High Pressure Liquid, Peroxidase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4249f4b654232581ca843188d16d13b3
https://doi.org/10.1074/jbc.m104263200 -
4Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA
المؤلفون: Philip G. Penketh, Sara Rockwell, Michael F. Belcourt, David H. Sherman, William F. Hodnick, David A. Johnson, Alan C. Sartorelli
المصدر: Proceedings of the National Academy of Sciences. 96:10489-10494
مصطلحات موضوعية: Cell Survival, Mitomycin, Drug Resistance, CHO Cells, Biology, Transfection, chemistry.chemical_compound, Bacterial Proteins, Cricetinae, Animals, Prodrugs, Cloning, Molecular, Biotransformation, Oxidase test, Multidisciplinary, Hydroquinone, Chinese hamster ovary cell, Mitomycin C, Biological Sciences, Prodrug, Molecular biology, Aerobiosis, Cell Hypoxia, Porfiromycin, Recombinant Proteins, Streptomyces, In vitro, Biochemistry, chemistry, Oxidoreductases, DNA
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078d4fdd740bcee122e14436ca1f242f
https://doi.org/10.1073/pnas.96.18.10489 -
5
المؤلفون: William F. Hodnick, Alan C. Sartorelli
المصدر: Analytical Biochemistry. 252:165-168
مصطلحات موضوعية: Dicumarol, Vitamin K, Aldo-Keto Reductases, Biophysics, CHO Cells, Biochemistry, Mice, Sonication, chemistry.chemical_compound, Menadione, Aldehyde Reductase, Oxidoreductase, Cricetinae, Metronidazole, NAD(P)H Dehydrogenase (Quinone), Animals, Humans, Dichlorophenolindophenol, Molecular Biology, Cells, Cultured, NADPH-Ferrihemoprotein Reductase, chemistry.chemical_classification, biology, Nitrofurazone, Cytochrome c, Cell Biology, Molecular biology, Bisulfite, Alcohol Oxidoreductases, Enzyme, chemistry, Cell culture, biology.protein, 2,6-Dichloroindophenol, NAD+ kinase
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6
المصدر: Biochemical Pharmacology. 51:1669-1678
مصطلحات موضوعية: Pharmacology, Dose-Response Relationship, Drug, Cell Survival, Mitomycin, Chinese hamster ovary cell, Ovary, Mitomycin C, CHO Cells, Transfection, Biology, Biochemistry, Molecular biology, In vitro, Enzyme Activation, Porfiromycin, Cell culture, Cricetinae, Toxicity, Animals, Female, Hypoxia, Cytotoxicity, Dihydrolipoamide Dehydrogenase
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7
المؤلفون: Alan C. Sartorelli, William F. Hodnick
المصدر: Cancer Letters. 84:149-154
مصطلحات موضوعية: chemistry.chemical_classification, Cancer Research, Reactive oxygen species, chemistry.chemical_element, Hydrogen-Ion Concentration, medicine.disease_cause, Quinone methide, Oxygen, Quinone, chemistry.chemical_compound, Oxygen Consumption, Enzyme, Oncology, chemistry, Biochemistry, Doxorubicin, medicine, Hydrogen peroxide, Oxidation-Reduction, Cytochrome Reductases, Cytochrome-B(5) Reductase, Cytochrome b5 reductase, Oxidative stress
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8
المؤلفون: Jianmin Wang, Laurel Faga, Joel Danzig, John J. Harrington, James T. Anderson, Anthony E. Ting, Alain Stricker-Krongrad, Kurt R. Brunden, William F. Hodnick, Youssef L. Bennani, Sherry Boozer, Robert Perry, Chris Crumrine, Stephen Rundlett, Gary Pawlowski, Amy Raber, Steven M. Murphy, Tom Dent
المصدر: Journal of medicinal chemistry. 48(23)
مصطلحات موضوعية: G2 Phase, Noscapine, Antineoplastic Agents, Chemical synthesis, Microtubules, Cell Line, chemistry.chemical_compound, Mice, Biopolymers, Tubulin, Drug Discovery, medicine, Animals, Humans, Natural product, Cell growth, Biological activity, Stereoisomerism, Cell cycle, Tubulin Modulators, chemistry, Biochemistry, Cell culture, Molecular Medicine, Antimitotic Agent, Drug Screening Assays, Antitumor, medicine.drug, HeLa Cells
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9
المؤلفون: Philip G. Penketh, Sara Rockwell, Maria Tomasz, Alan C. Sartorelli, Helen A. Seow, Michael F. Belcourt, William F. Hodnick
المصدر: Molecular pharmacology. 67(2)
مصطلحات موضوعية: Pharmacology, Cell Nucleus, Chinese hamster ovary cell, Cytochrome c, Endoplasmic reticulum, Mitomycin, Active Transport, Cell Nucleus, Drug Synergism, Transfection, CHO Cells, Biology, Reductase, Molecular biology, Cell culture, Cricetinae, biology.protein, Molecular Medicine, Cytotoxic T cell, Animals, Cytotoxicity, NADPH-Ferrihemoprotein Reductase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bb2c71c55e0390952a79dde28ebc20
https://pubmed.ncbi.nlm.nih.gov/15547247 -
10
المؤلفون: Bijan Almassian, John Mao, Xu Lin, Gopal Krishna, Srinivasa R. Karra, Wengsheng Lang, William F. Hodnick
مصطلحات موضوعية: Drug Compounding, Silicones, Pharmaceutical Science, Alcohol, Antineoplastic Agents, Aquatic Science, Article, Injections, chemistry.chemical_compound, Adsorption, Drug Stability, Drug Discovery, Infusions, Parenteral, Dimethylpolysiloxanes, Solubility, Ecology, Evolution, Behavior and Systematics, Sulfonamides, Chromatography, Ecology, Sterilization, General Medicine, Sterilization (microbiology), Hydrogen-Ion Concentration, Dilution, Partition coefficient, Membrane, Hydrazines, chemistry, Rubber, Citric acid, Agronomy and Crop Science
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b5eff2c95ae91fdd883e31d162eecf
https://europepmc.org/articles/PMC2750579/