المؤلفون: Willis, LF, Kumar, A, Dobson, J, Bond, NJ, Lowe, D, Turner, R, Radford, SE, Kapur, N, Brockwell, DJ

المصدر: Biotechnology and Bioengineering

مصطلحات موضوعية: Protein Denaturation, Bioprocess Engineering and Supporting Technologies, shear flow, bioprocessing, aggregation, Antibodies, Monoclonal, Articles, extensional flow, Article, Recombinant Proteins, Protein Aggregates, antibody, Immunoglobulin G, Protein Multimerization

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2f89f4249662833c3f0aac451d95bff9
http://europepmc.org/articles/PMC5900942

المؤلفون: Ulamec SM; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Maya-Martinez R; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Byrd EJ; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Dewison KM; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Xu Y; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Willis LF; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Sobott F; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Heath GR; Astbury Centre for Structural Molecular Biology, School of Physics & Astronomy, University of Leeds, Leeds, LS2 9JT, UK., van Oosten Hawle P; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK., Buchman VL; School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK.; Belgorod State National Research University, 85 Pobedy Street, Belgorod, 308015, Belgorod Region, Russian Federation., Radford SE; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. S.E.Radford@leeds.ac.uk., Brockwell DJ; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK. D.J.Brockwell@leeds.ac.uk.

المصدر: Nature communications [Nat Commun] 2022 Aug 25; Vol. 13 (1), pp. 4986. Date of Electronic Publication: 2022 Aug 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Amyloidosis* , Parkinson Disease*/genetics , Parkinson Disease*/metabolism, Amyloid/metabolism ; Amyloidogenic Proteins ; Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Humans ; alpha-Synuclein/metabolism

المؤلفون: Willis LF; School of Molecular and Cellular Biology, Faculty of Biological Sciences University of Leeds Leeds UK.; Astbury Centre for Structural Molecular Biology University of Leeds Leeds UK., Kumar A; School of Molecular and Cellular Biology, Faculty of Biological Sciences University of Leeds Leeds UK.; Astbury Centre for Structural Molecular Biology University of Leeds Leeds UK.; Department of Life Sciences Imperial College London London UK., Jain T; Adimab LLC Lebanon New Hampshire USA., Caffry I; Adimab LLC Lebanon New Hampshire USA.; Cornell Johnson Graduate School of Management Ithaca New York USA., Xu Y; Adimab LLC Lebanon New Hampshire USA.; Biotheus Inc. Zhuhai Guangdong Province China., Radford SE; School of Molecular and Cellular Biology, Faculty of Biological Sciences University of Leeds Leeds UK.; Astbury Centre for Structural Molecular Biology University of Leeds Leeds UK., Kapur N; School of Mechanical Engineering, Faculty of Engineering University of Leeds Leeds UK., Vásquez M; Adimab LLC Lebanon New Hampshire USA., Brockwell DJ; School of Molecular and Cellular Biology, Faculty of Biological Sciences University of Leeds Leeds UK.; Astbury Centre for Structural Molecular Biology University of Leeds Leeds UK.

المصدر: Engineering reports : open access [Eng Rep] 2020 May; Vol. 2 (5), pp. e12147. Date of Electronic Publication: 2020 Mar 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101769939 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2577-8196 (Electronic) Linking ISSN: 25778196 NLM ISO Abbreviation: Eng Rep Subsets: PubMed not MEDLINE

المؤلفون: Dobson J; School of Mechanical Engineering, University of Leeds, Leeds, LS2 9JT, United Kingdom., Kumar A; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom., Willis LF; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom., Tuma R; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom., Higazi DR; MedImmune Ltd., Cambridge, CB21 6GH, United Kingdom., Turner R; MedImmune Ltd., Cambridge, CB21 6GH, United Kingdom., Lowe DC; MedImmune Ltd., Cambridge, CB21 6GH, United Kingdom., Ashcroft AE; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom., Radford SE; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom., Kapur N; School of Mechanical Engineering, University of Leeds, Leeds, LS2 9JT, United Kingdom; N.Kapur@leeds.ac.uk d.j.brockwell@leeds.ac.uk., Brockwell DJ; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, United Kingdom; N.Kapur@leeds.ac.uk d.j.brockwell@leeds.ac.uk.; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 May 02; Vol. 114 (18), pp. 4673-4678. Date of Electronic Publication: 2017 Apr 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Hydrodynamics* , Protein Aggregates*, Antibodies, Monoclonal/*chemistry , Granulocyte Colony-Stimulating Factor/*chemistry , Serum Albumin, Bovine/*chemistry , beta 2-Microglobulin/*chemistry, Animals ; Cattle ; Humans ; Kinetics ; Protein Stability