يعرض 1 - 10 نتائج من 12 نتيجة بحث عن '"Willy A. Solis"', وقت الاستعلام: 1.11s تنقيح النتائج
  1. 1
    Site-Specific 89Zr- and 111In-Radiolabeling and In Vivo Evaluation of Glycan-free Antibodies by Azide–Alkyne Cycloaddition with a Non-natural Amino Acid

    المؤلفون: Willy A. Solis, Brett A. Vaughn, Eszter Boros, Trevor J. Hallam, Mark Lupher, Shin Hye Ahn

    المصدر: Bioconjugate Chemistry. 31:1177-1187

    مصطلحات موضوعية: Glycan, medicine.drug_class, Biomedical Engineering, Pharmaceutical Science, Alkyne, Bioengineering, 02 engineering and technology, Monoclonal antibody, 01 natural sciences, chemistry.chemical_compound, In vivo, medicine, Pharmacology, chemistry.chemical_classification, Bioconjugation, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, technology, industry, and agriculture, 021001 nanoscience & nanotechnology, Combinatorial chemistry, Cycloaddition, 0104 chemical sciences, Amino acid, body regions, biology.protein, Azide, 0210 nano-technology, Biotechnology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9740ae9a8b89b617f64f404c11fb8e90
    https://doi.org/10.1021/acs.bioconjchem.0c00100

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  2. 2
    Site-Specific

    المؤلفون: Shin Hye, Ahn, Brett A, Vaughn, Willy A, Solis, Mark L, Lupher, Trevor J, Hallam, Eszter, Boros

    المصدر: Bioconjugate chemistry. 31(4)

    مصطلحات موضوعية: Radioisotopes, Azides, Immunoconjugates, Cycloaddition Reaction, Indium Radioisotopes, Mice, Cell Transformation, Neoplastic, Alkynes, Cell Line, Tumor, Isotope Labeling, Animals, Humans, Zirconium, Amino Acids

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::af3d21603cb33741f37ce0a3d7803f23
    https://pubmed.ncbi.nlm.nih.gov/32138509

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  3. 3
    Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001

    المؤلفون: Willy A. Solis, Arturo Molina, Alice Yam, Ryan Stafford, Trevor J. Hallam, Kwun Wah Wen, Mark Lupher, Cristina Abrahams, Christopher Jones, Xiaofan Li, Millicent Embry, Stellanie Krimm, Venita DeAlmeida, Sarah Krueger, Nancy Y. Greenland, Shannon Matheny, Toni Kline, Arun P. Wiita, Abigail Yu

    المصدر: Oncotarget
    Oncotarget, vol 9, iss 102
    Abrahams, Cristina L; Li, Xiaofan; Embry, Millicent; Yu, Abigail; Krimm, Stellanie; Krueger, Sarah; et al.(2018). Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001.. Oncotarget, 9(102), 37700-37714. doi: 10.18632/oncotarget.26491. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2rh6994v

    مصطلحات موضوعية: 0301 basic medicine, Antibody-drug conjugate, Oncology and Carcinogenesis, antibody-drug conjugate, 03 medical and health sciences, Rare Diseases, 0302 clinical medicine, STRO-001, Clinical Research, medicine, Potency, Cytotoxicity, Multiple myeloma, Cancer, biology, Chemistry, Monocyte, Hematology, medicine.disease, multiple myeloma, Orphan Drug, 030104 developmental biology, medicine.anatomical_structure, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Pharmacodynamics, CD74, Cancer research, biology.protein, Immunohistochemistry, xenograft models, Development of treatments and therapeutic interventions, Antibody, Biotechnology, Research Paper

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137e1ebe00cf3bb8373f294a334b53ad
    https://pubmed.ncbi.nlm.nih.gov/30701025

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  4. 4
    Abstract NT-090: PRECLINICAL ACTIVITY AND SAFETY OF STRO-002, A NOVEL ADC TARGETING FOLATE RECEPTOR ALPHA FOR OVARIAN AND ENDOMETRIAL CANCER

    المؤلفون: Toni Kline, Sihong Zhou, Jeffrey A. Hanson, Mary Rose Masikat, Venita I. De Almeida, Ryan Stafford, Maureen Fitch Bruhns, Cristina Abrahams, Gang Yin, Willy A. Solis, Krishna Bajjuri, Alexander Steiner, Adam Galan, Xiaofan Li, Cuong D. Tran, Stellanie Krimm, Alice Yam, Abigail Yu, Trevor J. Hallam, Mark Lupher, Robert Henningsen, Julie Hang, Tyler H. Heibeck, Dharti Kothari, James Zawada

    المصدر: Clinical Cancer Research. 25:NT-090

    مصطلحات موضوعية: Folate Receptor Alpha, Cancer Research, business.industry, Endometrial cancer, Cancer, medicine.disease, Carboplatin, chemistry.chemical_compound, Oncology, chemistry, In vivo, Toxicity, medicine, Cancer research, Cytotoxic T cell, Ovarian cancer, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::acaa1d4bcef805a7b50ae79f4eceb2c5
    https://doi.org/10.1158/1557-3265.ovcasymp18-nt-090

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  5. 5
    Preclinical activity and safety of STRO-002, a novel ADC targeting folate receptor alpha for ovarian cancer

    المؤلفون: Mark Lupher, Toni Kline, Jeffrey A. Hanson, G. Sarma, V. De Almeida, Xiaolin Li, James Zawada, Willy A. Solis, Cristina Abrahams, Mary Rose Masikat

    المصدر: Gynecologic Oncology. 149:50

    مصطلحات موضوعية: Folate Receptor Alpha, Oncology, business.industry, Cancer research, Obstetrics and Gynecology, Medicine, business, Ovarian cancer, medicine.disease

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::06375687f94d44524e19c5ca66b8161c
    https://doi.org/10.1016/j.ygyno.2018.04.109

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  6. 6
    Glutamate–cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress

    المؤلفون: Timothy P. Dalton, Sarah L Freshwater, Willy A. Solis, Howard G. Shertzer, Judy M. Harrer, Lei He, Daniel W. Nebert, Matthew Z. Dieter

    المصدر: Biochemical Pharmacology. 63:1739-1754

    مصطلحات موضوعية: Transcription, Genetic, 5' Flanking Region, Glutamate-Cysteine Ligase, TATA box, Molecular Sequence Data, Response element, Biology, Biochemistry, Antioxidants, Mice, Transcription (biology), Sequence Homology, Nucleic Acid, Gene expression, Tumor Cells, Cultured, Animals, RNA, Messenger, Promoter Regions, Genetic, Gene, Pharmacology, chemistry.chemical_classification, DNA ligase, Genome, Base Sequence, GCLM, Vitamin K 3, DNA, Hydrogen Peroxide, Glutathione, TATA Box, Molecular biology, Hydroquinones, Oxidative Stress, Protein Subunits, GCLC, Gene Expression Regulation, chemistry, Transcription Initiation Site, Cadmium

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2c4c80163f9bac15e7e6e1fa793483
    https://doi.org/10.1016/s0006-2952(02)00897-3

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  7. 7
    Tryphostin AG879, a tyrosine kinase inhibitor: prevention of transcriptional activation of the electrophile and the aromatic hydrocarbon response elements11Abbreviations: EPRE, electrophile response element; AHRE, aromatic hydrocarbon response element; MRE, metal response element; Nqo1 and NQO1, mouse NAD(P)H:quinone oxidoreductase [also called NMO1, quinone reductase, DT-diaphorase] gene and mRNA; Cyp1a1 and CYP1A1, mouse cytochrome P450 1A1 gene and mRNA; Mt1 and MT1, mouse metallothionein-1 gene and mRNA; Sod, mouse Cu,Zn-superoxide dismutase gene; SOD, rat Cu,Zn-superoxide dismutase gene; SOD, mouse and rat Cu,Zn-superoxide dismutase mRNA and protein; Luc and LUC, firefly luciferase gene and enzyme; BGAL, β-galactosidase enzyme activity; tBHQ, tert-butylhydroquinone; dioxin (also TCDD), 2,3,7,8-tetrahydro chlorodibenzo-p-dioxin; SSC, standard sodium citrate; and SET, sodium ethylenediamine tetraacetic acid (EDTA) Tris buffer

    المؤلفون: Daniel W. Nebert, Matthew Z. Dieter, Timothy P. Dalton, Willy A. Solis, Sarah L Freshwater

    المصدر: Biochemical Pharmacology. 61:215-225

    مصطلحات موضوعية: Pharmacology, Chemistry, medicine.drug_class, Response element, Tyrphostins, Biochemistry, Tyrosine-kinase inhibitor, Cell biology, Transcription (biology), Transcriptional regulation, medicine, Phosphorylation, Signal transduction, Tyrosine kinase

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b88dd331463ddae19557f1be76db729b
    https://doi.org/10.1016/s0006-2952(00)00525-6

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  8. 8
    Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

    المؤلفون: Amy L. Roe, Willy A. Solis, Daniel W. Nebert, Matthew Z. Dieter, Yi Yang, Timothy P. Dalton

    المصدر: Biochemical Pharmacology. 59:65-85

    مصطلحات موضوعية: Response element, Aromatic hydrocarbon receptor, Apoptosis, Mitochondrion, medicine.disease_cause, Biochemistry, medicine, Animals, Humans, Receptor, Pharmacology, biology, Tyrosinemias, Cell Cycle, Cytochrome P450, Receptor Cross-Talk, Cell cycle, Glutathione, Oxidative Stress, Receptors, Aryl Hydrocarbon, biology.protein, Tyrosine, Signal transduction, Oxidative stress, Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d288f0fff3d844620df4aaef5e16ed
    https://doi.org/10.1016/s0006-2952(99)00310-x

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  9. 9
    Trout CYP1A3 Gene: Recognition of Fish DNA Motifs by Mouse Regulatory Proteins

    المؤلفون: Alvaro Puga, Willy A. Solis, Daniel W. Nebert, Michael J. Carvan, Larissa V. Ponomareva, Robin S. Matlib

    المصدر: Marine Biotechnology. 1:155-166

    مصطلحات موضوعية: Trout, Reporter gene, Aryl hydrocarbon receptor nuclear translocator, biology, Rainbow trout, Luciferase, Promoter, respiratory system, biology.organism_classification, Applied Microbiology and Biotechnology, Molecular biology, Gene, Primer extension

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1dae3f7868b81f811ff83be25ede80
    https://doi.org/10.1007/pl00011763

    Find this article in full text from Springer Verlag. Find this article in full text from ProQuest
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  10. 10
    Use of reporter genes and vertebrate DNA motifs in transgenic zebrafish as sentinels for assessing aquatic pollution

    المؤلفون: Daniel W, Nebert, Gary W, Stuart, Willy A, Solis, Michael J, Carvan

    المصدر: Environmental Health Perspectives

    مصطلحات موضوعية: animal structures, Health, Toxicology and Mutagenesis, Animals, Genetically Modified, chemistry.chemical_compound, Plasmid, Genes, Reporter, biology.animal, Transgenic zebrafish, Animals, heterocyclic compounds, Water Pollutants, Luciferases, Zebrafish, Regulation of gene expression, Genetics, Reporter gene, biology, Pigmentation, Water pollutants, fungi, Public Health, Environmental and Occupational Health, Vertebrate, DNA, respiratory system, biology.organism_classification, Coleoptera, chemistry, Gene Expression Regulation, Biomarkers, Plasmids, Research Article

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ed7586e07de534b890fce4b8cc93c9
    https://pubmed.ncbi.nlm.nih.gov/11564622

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