نتائج البحث - "Wim J Quax"

المساهمون: Chemical and Pharmaceutical Biology, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Medicinal Chemistry and Bioanalysis (MCB)

المصدر: Bioorganic Chemistry, 136:106546

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Molecular Biology, Biochemistry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc9492662efcf45a8eb34bc2e087c04
https://doi.org/10.1016/j.bioorg.2023.106546

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Data from Enhanced Antitumor Efficacy of a DR5-Specific TRAIL Variant over Recombinant Human TRAIL in a Bioluminescent Ovarian Cancer Xenograft Model

المؤلفون: Steven de Jong, Ate G.J. van der Zee, Afshin Samali, Wim J. Quax, Robbert H. Cool, Go M. van Dam, Marjolijn N. Lub-de Hooge, Harry Hollema, Wytske Boersma-van Ek, Gert Jan Meersma, Devalingam Mahalingam, Elisabeth G.E. de Vries, Evelien W. Duiker

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de1aa6de34f8c61e65e11b595f96203
https://doi.org/10.1158/1078-0432.c.6517572

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Supplementary Data from Enhanced Antitumor Efficacy of a DR5-Specific TRAIL Variant over Recombinant Human TRAIL in a Bioluminescent Ovarian Cancer Xenograft Model

المؤلفون: Steven de Jong, Ate G.J. van der Zee, Afshin Samali, Wim J. Quax, Robbert H. Cool, Go M. van Dam, Marjolijn N. Lub-de Hooge, Harry Hollema, Wytske Boersma-van Ek, Gert Jan Meersma, Devalingam Mahalingam, Elisabeth G.E. de Vries, Evelien W. Duiker

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffe0a61c021d5d18b2c2caa625e976e
https://doi.org/10.1158/1078-0432.22440219

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دورية أكاديمية

Metabolic Engineering of Bacillus subtilis Toward Taxadiene Biosynthesis as the First Committed Step for Taxol Production

المؤلفون: Ingy I. Abdallah, Hegar Pramastya, Ronald van Merkerk, Sukrasno, Wim J. Quax

المصدر: Frontiers in Microbiology, Vol 10 (2019)

مصطلحات موضوعية: Bacillus subtilis, metabolite, MEP, GGPPS, taxadiene, Taxol, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2019.00218/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/94d71e8b96464264a959f363f9771697

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دورية أكاديمية

Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

المؤلفون: Jan-Ytzen van der Meer, Harshwardhan Poddar, Bert-Jan Baas, Yufeng Miao, Mehran Rahimi, Andreas Kunzendorf, Ronald van Merkerk, Pieter G. Tepper, Edzard M. Geertsema, Andy-Mark W. H. Thunnissen, Wim J. Quax, Gerrit J. Poelarends

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/9cfd7194e093495a81ae07646995d9a2

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Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells

المؤلفون: Zhangping Xiao, Gerrit J. Poelarends, Wim J. Quax, Shanshan Song, Barbro N. Melgert, Frank J. Dekker, Robbert H. Cool, Deng Chen, Ronald van Merkerk, Petra E van der Wouden

المساهمون: Chemical and Pharmaceutical Biology, Molecular Pharmacology, Chemical and Pharmaceutical Biology (GRIP), Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED), Medicinal Chemistry and Bioanalysis (MCB)

المصدر: Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English), 60(32), 17514-17521. WILEY-V C H VERLAG GMBH

مصطلحات موضوعية: MAPK/ERK pathway, Cell cycle checkpoint, Macrophage migration inhibitory factor (MIF), 01 natural sciences, proteolysis targeting chimera (PROTACs), ACTIVATION, BINDING, A549 cells, Research Articles, Chemistry, General Medicine, respiratory system, Small molecule, Cell biology, G2 Phase Cell Cycle Checkpoints, Intramolecular Oxidoreductases, cell cycle arrest, Cancer Therapy | Hot Paper, medicine.symptom, Research Article, MAP Kinase Signaling System, PROTEINS, Ubiquitin-Protein Ligases, Inflammation, Antineoplastic Agents, Phthalimides, chemical and pharmacologic phenomena, TAUTOMERASE INHIBITORS, 010402 general chemistry, Mitogen-activated protein kinase (MAPK) pathway, Catalysis, PROBES, Spheroids, Cellular, medicine, otorhinolaryngologic diseases, Humans, CYCLE, Macrophage Migration-Inhibitory Factors, Adaptor Proteins, Signal Transducing, Cell Proliferation, A549 cell, COMPLEX, 010405 organic chemistry, POTENT, Proteolysis targeting chimera, Cancer, General Chemistry, medicine.disease, 0104 chemical sciences, Benzoxazines, DISCOVERY, Proteolysis, Macrophage migration inhibitory factor, Drug Screening Assays, Antitumor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d51164a0c04702db2c8059a858ded3
https://doi.org/10.1002/anie.202101864

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