المؤلفون: Olah SS; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Kareemo DJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Buchta WC; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Sinnen BL; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Miller CN; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Actor-Engel HS; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Gookin SE; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Winborn CS; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Kleinjan MS; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Crosby KC; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Aoto J; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Smith KR; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Kennedy MJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: matthew.kennedy@cuanschutz.edu.

المصدر: Cell reports [Cell Rep] 2023 Nov 28; Vol. 42 (11), pp. 113331. Date of Electronic Publication: 2023 Oct 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, GABA-A* , Synapses*/physiology, Carrier Proteins ; Receptors, Neurotransmitter ; gamma-Aminobutyric Acid

المؤلفون: Wang S; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100029, China., Chen X; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA., Crisman L; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA., Dou X; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA., Winborn CS; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Wan C; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA., Puscher H; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA., Yin Q; Department of Biological Sciences and Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA., Kennedy MJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Shen J; Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.

المصدر: Science advances [Sci Adv] 2023 Feb 22; Vol. 9 (8), pp. eade2540. Date of Electronic Publication: 2023 Feb 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2*, Humans ; GTP Phosphohydrolases/metabolism ; Membrane Proteins/metabolism ; Exocytosis ; Guanosine Triphosphate/metabolism ; Calcium-Binding Proteins ; ATP-Binding Cassette Transporters ; GTPase-Activating Proteins/metabolism ; ral GTP-Binding Proteins/metabolism

المؤلفون: Actor-Engel HS; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Schwartz SL; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Crosby KC; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Sinnen BL; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Prikhodko O; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Ramsay HJ; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Bourne JN; Electron Microscopy Core, University of Colorado Anschutz Medical Campus, Aurora, CO 80045., Winborn CS; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Lucas A; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Smith KR; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Dell'Acqua ML; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045., Kennedy MJ; Department of Pharmacology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045 matthew.kennedy@cuanschutz.edu.

المصدر: ENeuro [eNeuro] 2021 Dec 17; Vol. 8 (6). Date of Electronic Publication: 2021 Dec 17 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease* , Amyloid beta-Peptides*, Humans ; Neuronal Plasticity ; Neurons ; Synapses

المؤلفون: Bourke AM; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO., Schwartz SL; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO., Bowen AB; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO., Kleinjan MS; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO., Winborn CS; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO., Kareemo DJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO., Gutnick A; Department of Neurobiology, Harvard Medical School, Boston, MA., Schwarz TL; Department of Neurobiology, Harvard Medical School, Boston, MA.; F.M. Kirby Neurobiology Center, Children's Hospital, Boston, MA., Kennedy MJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO.

المصدر: The Journal of cell biology [J Cell Biol] 2021 Sep 06; Vol. 220 (9). Date of Electronic Publication: 2021 Jul 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane/*metabolism , Endoplasmic Reticulum/*metabolism , Neurons/*metabolism , Secretory Pathway/*genetics , Synapses/*metabolism , Synaptic Transmission/*genetics, Animals ; Animals, Newborn ; Cell Adhesion Molecules, Neuronal/genetics ; Cell Adhesion Molecules, Neuronal/metabolism ; Cell Membrane/ultrastructure ; Endoplasmic Reticulum/ultrastructure ; Female ; Fluorescent Dyes/chemistry ; Gene Expression ; Golgi Apparatus/metabolism ; Golgi Apparatus/ultrastructure ; Hippocampus/cytology ; Hippocampus/metabolism ; Light ; Male ; Molecular Imaging/methods ; Neurons/cytology ; Primary Cell Culture ; Protein Transport ; Rats ; Rats, Sprague-Dawley ; Receptors, AMPA/genetics ; Receptors, AMPA/metabolism ; Synapses/ultrastructure ; Tacrolimus Binding Proteins/genetics ; Tacrolimus Binding Proteins/metabolism ; Tetrahydrofolate Dehydrogenase/genetics ; Tetrahydrofolate Dehydrogenase/metabolism

المؤلفون: Martin MD; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA., Sompallae R; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA., Winborn CS; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA., Harty JT; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA 52242, USA; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242, USA., Badovinac VP; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA 52242, USA; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242, USA. Electronic address: vladimir-badovinac@uiowa.edu.

المصدر: Cell reports [Cell Rep] 2020 Apr 14; Vol. 31 (2), pp. 107508.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: CD8-Positive T-Lymphocytes/*immunology , Immunologic Memory/*immunology , T-Lymphocytes/*immunology, Animals ; Crosses, Genetic ; Female ; Genetic Variation/genetics ; Genotype ; Haplotypes/genetics ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred Strains ; Models, Immunological ; Phenotype ; Quantitative Trait Loci/genetics ; T-Lymphocytes/metabolism ; Virus Diseases/genetics

المؤلفون: Danahy DB; Department of Pathology, University of Iowa, Iowa City, IA 52242.; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242., Kurup SP; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242; and., Winborn CS; Department of Pathology, University of Iowa, Iowa City, IA 52242., Jensen IJ; Department of Pathology, University of Iowa, Iowa City, IA 52242.; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242., Harty JT; Department of Pathology, University of Iowa, Iowa City, IA 52242.; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242.; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242; and., Griffith TS; Department of Urology, University of Minnesota, Minneapolis, MN 55414., Badovinac VP; Department of Pathology, University of Iowa, Iowa City, IA 52242; vladimir-badovinac@uiowa.edu.; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242.; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242; and.

المصدر: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2019 Aug 01; Vol. 203 (3), pp. 725-735. Date of Electronic Publication: 2019 Jun 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Antigens, CD/*metabolism , CD8-Positive T-Lymphocytes/*immunology , Lymphocytes, Tumor-Infiltrating/*immunology , Melanoma, Experimental/*immunology , Programmed Cell Death 1 Receptor/*metabolism , Sepsis/*immunology, Animals ; Antibodies, Monoclonal/immunology ; Antigens, CD/immunology ; Cecum/surgery ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease Models, Animal ; Female ; Lymphocyte Count ; Male ; Melanoma, Experimental/pathology ; Mice ; Mice, Inbred C57BL ; Programmed Cell Death 1 Receptor/immunology ; Lymphocyte Activation Gene 3 Protein

المؤلفون: Jensen IJ; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America.; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Winborn CS; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Fosdick MG; Interdisciplinary Graduate Program in Molecular Medicine, University of Iowa, Iowa City, Iowa, United States of America., Shao P; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America., Tremblay MM; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America., Shan Q; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America., Tripathy SK; Gastroenterology Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America., Snyder CM; Department of Immunology and Microbiology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America., Xue HH; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America.; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America., Griffith TS; Microbiology, Immunology, and Cancer Biology Ph.D. Program, University of Minnesota, Minneapolis, Minnesota, United States of America.; Center for Immunology, University of Minnesota, Minneapolis, Minnesota, United States of America.; Department of Urology, University of Minnesota, Minneapolis, Minnesota, United States of America.; Minneapolis VA Health Care, University of Minnesota, Minneapolis, Minnesota, United States of America., Houtman JC; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America.; Interdisciplinary Graduate Program in Molecular Medicine, University of Iowa, Iowa City, Iowa, United States of America.; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America., Badovinac VP; Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America.; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America.; Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, United States of America.

المصدر: PLoS pathogens [PLoS Pathog] 2018 Oct 31; Vol. 14 (10), pp. e1007405. Date of Electronic Publication: 2018 Oct 31 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

مواضيع طبية MeSH: Cytomegalovirus Infections/*immunology , Immunity, Cellular/*immunology , Killer Cells, Natural/*immunology , Muromegalovirus/*immunology , NK Cell Lectin-Like Receptor Subfamily A/*metabolism , Sepsis/*immunology, Animals ; Cells, Cultured ; Cytokines/metabolism ; Cytomegalovirus Infections/virology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Perforin/physiology

المؤلفون: Bhattacharya S; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States., Yin J; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States., Winborn CS; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States., Zhang Q; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States., Yue J; Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, United States., Chaum E; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States 3Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States.

المصدر: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2017 Apr 01; Vol. 58 (4), pp. 2366-2387.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation*, AC133 Antigen/*genetics , Autophagy/*genetics , Macular Degeneration/*genetics , RNA/*genetics , Retinal Pigment Epithelium/*metabolism, AC133 Antigen/biosynthesis ; Adult ; Aged ; Animals ; Blotting, Western ; Cells, Cultured ; Female ; Flow Cytometry ; Humans ; Immunoprecipitation ; Macular Degeneration/metabolism ; Macular Degeneration/pathology ; Male ; Microscopy, Confocal ; Middle Aged ; Rabbits ; Real-Time Polymerase Chain Reaction ; Retinal Pigment Epithelium/pathology ; Signal Transduction ; Young Adult

المؤلفون: Chaum E; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN, 38163, USA, echaum@uthsc.edu., Winborn CS, Bhattacharya S

المصدر: Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2015 Jun; Vol. 26 (5-6), pp. 210-21. Date of Electronic Publication: 2015 May 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: United States NLM ID: 9100916 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1777 (Electronic) Linking ISSN: 09388990 NLM ISO Abbreviation: Mamm Genome Subsets: MEDLINE

مواضيع طبية MeSH: Aging*, Immunity, Innate/*genetics , Retinal Pigment Epithelium/*metabolism , Tumor Suppressor Protein p53/*metabolism, Adult ; Aged, 80 and over ; Animals ; Apoptosis ; Caspases/genetics ; Caspases/metabolism ; Caspases, Initiator ; Cell Line ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/genetics ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Gene Expression Regulation ; Humans ; Interferon-alpha/genetics ; Interferon-alpha/metabolism ; Interferon-gamma/genetics ; Interferon-gamma/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Inbred DBA ; Primary Cell Culture ; Quantitative Trait Loci ; Retinal Pigment Epithelium/cytology ; Signal Transduction ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Tumor Suppressor Protein p53/genetics

المؤلفون: Alami NH; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Smith RB; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Carrasco MA; Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA., Williams LA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138., Winborn CS; Department of Ophthalmology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA., Han SSW; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138.; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA., Kiskinis E; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138., Winborn B; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Freibaum BD; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Kanagaraj A; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Clare AJ; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Badders NM; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Bilican B; Euan MacDonald Centre for Motor Neurone Disease Research, Medical Research Council Centre for Regenerative Medicine, Centre for Neuroregeneration, University of Edinburgh, Edinburgh EH16 4SB, UK., Chaum E; Department of Ophthalmology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA., Chandran S; Euan MacDonald Centre for Motor Neurone Disease Research, Medical Research Council Centre for Regenerative Medicine, Centre for Neuroregeneration, University of Edinburgh, Edinburgh EH16 4SB, UK., Shaw CE; Departments of Clinical Neuroscience and Neurodegeneration and Brain Injury, King's College London and King's Health Partners, MRC Centre for Neurodegeneration Research, London SE5 8AF, UK., Eggan KC; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138., Maniatis T; Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA., Taylor JP; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

المصدر: Neuron [Neuron] 2014 Feb 05; Vol. 81 (3), pp. 536-543.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*pathology , Axonal Transport/*genetics , DNA-Binding Proteins/*genetics , Motor Neurons/*metabolism , Mutation/*genetics , RNA, Messenger/*metabolism, Amyotrophic Lateral Sclerosis/genetics ; Animals ; Animals, Genetically Modified ; Cells, Cultured ; Cerebral Cortex/cytology ; Drosophila ; Drosophila Proteins/genetics ; Humans ; Kruppel-Like Factor 4 ; Kruppel-Like Transcription Factors/genetics ; Kruppel-Like Transcription Factors/metabolism ; Luminescent Proteins/genetics ; Mice ; Mitochondria/metabolism ; Motor Neurons/ultrastructure ; Octamer Transcription Factor-3/genetics ; Octamer Transcription Factor-3/metabolism ; RNA-Binding Proteins/metabolism ; SOXB1 Transcription Factors/genetics ; SOXB1 Transcription Factors/metabolism