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1دورية أكاديمية
المؤلفون: Pakkasjarvi, N, Syvanen, J, Wiro, M, Koskimies-Virta, E
المصدر: Birth defects research. 114(20):1427-1433
مصطلحات موضوعية: Medicin och hälsovetenskap
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2دورية أكاديمية
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3دورية أكاديمية
المؤلفون: Malan, Sarel F. *, Marle, Andre van, Menge, Wiro M., Zuliana, Valentina, Hoffman, Marcel, Timmerman, Henk, Leurs, Rob
المصدر: In Bioorganic & Medicinal Chemistry 2004 12(24):6495-6503
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المؤلفون: J. M. Te Koppele, G. M. Donne-Op Den Kelder, J.H. van Lenthe, L. M. H. Koymans, Wiro M. P. B. Menge, Nico P. E. Vermeulen
المصدر: Recueil des Travaux Chimiques des Pays-Bas. 112:186-190
مصطلحات موضوعية: chemistry.chemical_classification, Oxidative metabolism, biology, Stereochemistry, Cytochrome P450, Substrate (chemistry), General Chemistry, Hydrogen atom abstraction, Photochemistry, Decomposition, chemistry.chemical_compound, Enzyme, chemistry, biology.protein, Side chain, Hydroxyl radical
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6252b4085c12b443c3ff40d181de3b2a
https://doi.org/10.1002/recl.19931120217 -
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المؤلفون: I.J.P. de Esch, Lindsay B. Hough, Wiro M. P. B. Menge, A. C. Van De Stolpe, Julia W. Nalwalk, Rob Leurs
المساهمون: Medicinal chemistry
المصدر: Hough, L H, Menge, W M P B, van de Stolpe, A, Nalwalk, J B, Leurs, R & de Esch, I J P 2007, ' Antinociceptive activity of furan-containing congeners of improgan and ranitidine ', Bioorganic and Medicinal Chemistry Letters, vol. 17, no. 20, pp. 5715-9 . https://doi.org/10.1016/j.bmcl.2007.07.060
Bioorganic and Medicinal Chemistry Letters, 17(20), 5715-9. Elsevier Limitedمصطلحات موضوعية: Male, Tertiary amine, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Analgesic, Pharmaceutical Science, Ranitidine, Biochemistry, Article, Rats, Sprague-Dawley, Structure-Activity Relationship, Histamine H2 receptor, Drug Discovery, medicine, Animals, Potency, Cimetidine, Furans, Molecular Biology, Molecular Structure, Chemistry, Organic Chemistry, Antagonist, Nociceptors, Receptor antagonist, Rats, Molecular Medicine, medicine.drug
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المؤلفون: Iwan J. P. de Esch, Dris El-Atmioui, Remko A. Bakker, Wiro M. P. B. Menge, Rob Leurs, Herman D. Lim, Marinella Govoni, Henk Timmerman
المساهمون: Medicinal chemistry, Chemistry and Pharmaceutical Sciences
المصدر: Govoni, M, Lim, H D, El-Atmioui, D, Menge, W M P B, Timmerman, H, Bakker, R A, Leurs, R & De Esch, I J 2006, ' A chemical switch for the modulation of the functional activity of higher homologues of histamine on the human histamine H3 receptor: effect of various substitutions at the primary amino function ', Journal of Medicinal Chemistry, vol. 49, no. 8, pp. 2549-57 . https://doi.org/10.1021/jm0504353
Journal of Medicinal Chemistry, 49(8), 2549-57. American Chemical Societyمصطلحات موضوعية: Tertiary amine, Stereochemistry, Ligands, Chemical synthesis, Receptors, G-Protein-Coupled, Structure-Activity Relationship, Alicyclic compound, chemistry.chemical_compound, SDG 3 - Good Health and Well-being, Drug Discovery, Radioligand, Humans, Receptors, Histamine H3, Inverse agonist, Amines, Receptors, Histamine H4, chemistry.chemical_classification, Molecular Structure, Biological activity, Biochemistry, chemistry, Receptors, Histamine, Molecular Medicine, Histamine H3 receptor, Histamine
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المؤلفون: L.H. Hough, Henk Timmerman, Rob Leurs, Wiro M. P. B. Menge, J.B. Nalwalk
المساهمون: Medicinal chemistry, Chemistry and Pharmaceutical Sciences
المصدر: Hough, L H, Nalwalk, J B, Menge, W M P B, Leurs, R & Timmerman, H 2004, ' Improgan-like analgesics: A family of compounds derived from histamine antagonists ', Medicinal Chemistry Research, vol. 13, no. 1-2, pp. 78-87 . https://doi.org/10.1007/s00044-004-0012-z
Medicinal Chemistry Research, 13(1-2), 78-87. Birkhause Bostonمصطلحات موضوعية: Nucleus raphe magnus, Adrenergic receptor, Organic Chemistry, Pharmacology, Periaqueductal gray, chemistry.chemical_compound, Nociception, SDG 3 - Good Health and Well-being, chemistry, Opioid, Mechanism of action, medicine, General Pharmacology, Toxicology and Pharmaceutics, medicine.symptom, Receptor, Histamine, medicine.drug
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المؤلفون: Valentina Zuliana, Sarel F. Malan, Marcel Hoffman, Wiro M. P. B. Menge, André van Marle, Rob Leurs, Henk Timmerman
المساهمون: Medicinal chemistry, Chemistry and Pharmaceutical Sciences
المصدر: Malan, S F, van Marle, A, Menge, W M P B, Zuliana, V, Hoffman, M, Timmerman, H & Leurs, R 2004, ' Fluorescent ligands for the histamine H2 receptor: synthesis and preliminary characterization ', Bioorganic and Medicinal Chemistry, vol. 12, no. 24, pp. 6495-503 . https://doi.org/10.1016/j.bmc.2004.09.018
Bioorganic and Medicinal Chemistry, 12(24), 6495-503. Elsevier Limitedمصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Ether, Ligands, Guanidines, Biochemistry, Chemical synthesis, Iodine Radioisotopes, Radioligand Assay, chemistry.chemical_compound, Piperidines, Histamine H2 receptor, Drug Discovery, Humans, Receptors, Histamine H2, Guanidine, Molecular Biology, Alkyl, Fluorescent Dyes, chemistry.chemical_classification, Ligand, Organic Chemistry, Fluorescence, chemistry, Molecular Medicine, SDG 6 - Clean Water and Sanitation, Linker, Protein Binding
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المؤلفون: Obbe P. Zuiderveld, Roeland C. Vollinga, Ruengwit Kitbunnadaj, Henk Timmerman, Rob Leurs, Anthony L. Spek, Marie-France Deltent, Martin Lutz, Iwan J. P. de Esch, Emile Cavoy, Remko A. Bakker, Wiro M. P. B. Menge
المساهمون: Medicinal chemistry, Chemistry and Pharmaceutical Sciences, R¿ntgenparticipatieprogramma, Crystal and Structural Chemistry 2, Dep Natuurkunde, Dep Scheikunde
المصدر: Kitbunnadaj, R, Zuiderveld, O P, De Esch, I J, Vollinga, R C, Bakker, R A, Lutz, M, Spek, A L, Cavoy, E, Deltent, M F, Menge, W M P B, Timmerman, H & Leurs, R 2003, ' Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists ', Journal of Medicinal Chemistry, vol. 46, no. 25, pp. 5445-57 . https://doi.org/10.1021/jm030905y
Journal of Medicinal Chemistry, 46(25), 5445-57. American Chemical Societyمصطلحات موضوعية: Agonist, Pyrrolidines, Stereochemistry, medicine.drug_class, Histamine Antagonists, Molecular Conformation, Crystallography, X-Ray, Ligands, Binding, Competitive, Pyrrolidine, Histamine agonist, Cell Line, Receptors, G-Protein-Coupled, Histamine Agonists, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, SDG 3 - Good Health and Well-being, Drug Discovery, Cyclic AMP, medicine, Humans, Receptors, Histamine H3, Histamine H4 receptor, Receptors, Histamine H4, Chemistry, Imidazoles, Stereoisomerism, Immepip, Receptors, Histamine, Molecular Medicine, Colorimetry, Piperidine, Histamine H3 receptor, Histamine
وصف الملف: image/pdf
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المساهمون: Medicinal chemistry
المصدر: Gelens, E, Menge, W M P B, Koot, W J, Ottenheijm, H C J & Timmerman, H 2003, ' Solid-phase synthesis of heterocyclic aromates: applicability towards combinatorial Chemistry: a review ', Combinatorial Chemistry and High Throughput Screening, vol. 6, pp. 79-99 . https://doi.org/10.2174/1386207033329850
Combinatorial Chemistry and High Throughput Screening, 6, 79-99. Bentham Science Publishers B.V.مصطلحات موضوعية: Spatial positioning, Chemistry, Organic Chemistry, General Medicine, Combinatorial chemistry, Hydrocarbons, Aromatic, Catalysis, Computer Science Applications, Structure-Activity Relationship, Solid-phase synthesis, Heterocyclic Compounds, Drug Discovery, Organic chemistry, Combinatorial Chemistry Techniques, Palladium
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3270a1aa037b9146044b7e1701b6cc0d
https://hdl.handle.net/1871.1/3e4a8948-2b3c-4661-9878-e31422f056db
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