المؤلفون: Gilbert, Luke, Horlbeck, MA, Witkowsky, LB, Guglielmi, B, Replogle, JM, Gilbert, LA, Villalta, JE, Torigoe, SE, Tjian, R, Weissman, JS

URL الوصول: https://escholarship.org/uc/item/6pf7m64m

المؤلفون: Stahl EC; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Gopez AR; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Tsuchida CA; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Fan VB; University of California, Berkeley, Berkeley, CA, United States of America., Moehle EA; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Witkowsky LB; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Hamilton JR; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Lin-Shiao E; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., McElroy M; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., McDevitt SL; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Ciling A; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Tsui CK; University of California, Berkeley, Berkeley, CA, United States of America., Pestal K; University of California, Berkeley, Berkeley, CA, United States of America., Gildea HK; University of California, Berkeley, Berkeley, CA, United States of America., Keller A; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Sylvain IA; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Williams C; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Hirsh A; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Ehrenberg AJ; University of California, Berkeley, Berkeley, CA, United States of America., Kantor R; University of California, Berkeley, Berkeley, CA, United States of America.; Department of Civil and Environmental Engineering, University of California, Berkeley, CA, United States of America., Metzger M; University of California, Berkeley, Berkeley, CA, United States of America.; Department of Civil and Environmental Engineering, University of California, Berkeley, CA, United States of America., Nelson KL; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America.; Department of Civil and Environmental Engineering, University of California, Berkeley, CA, United States of America., Urnov FD; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Ringeisen BR; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Giannikopoulos P; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America., Doudna JA; University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, CA, United States of America.

مؤلفون مشاركون: IGI Testing Consortium

المصدر: PloS one [PLoS One] 2021 Nov 10; Vol. 16 (11), pp. e0258263. Date of Electronic Publication: 2021 Nov 10 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19/*virology , Ribonuclease P/*genetics , SARS-CoV-2/*genetics , Wastewater/*virology, DNA Primers/genetics ; Humans ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction/methods ; Sensitivity and Specificity ; Specimen Handling/methods ; Wastewater-Based Epidemiological Monitoring

المؤلفون: Hamilton JR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Stahl EC; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Tsuchida CA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America.; San Francisco Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, United States of America., Lin-Shiao E; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Tsui CK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America., Pestal K; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America., Gildea HK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America., Witkowsky LB; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Moehle EA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., McDevitt SL; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., McElroy M; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Keller A; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Sylvain I; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Hirsh A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Ciling A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Ehrenberg AJ; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America.; Department of Integrative Biology, University of California, Berkeley, Berkeley, CA, United States of America., Ringeisen BR; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Huberty G; Washington Hospital Healthcare System Clinical Laboratory, Fremont, CA, United States of America., Urnov FD; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Giannikopoulos P; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America., Doudna JA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, United States of America.; Gladstone Institutes, San Francisco, CA, United States of America.; Graduate Group in Biophysics, University of California, Berkeley, Berkeley, CA, United States of America.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, United States of America.; Department of Chemistry, University of California, Berkeley, Berkeley, CA, United States of America.

مؤلفون مشاركون: IGI SARS-CoV-2 Consortium

المصدر: PloS one [PLoS One] 2021 Aug 05; Vol. 16 (8), pp. e0255690. Date of Electronic Publication: 2021 Aug 05 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19 Testing/*methods , RNA, Viral/*isolation & purification , SARS-CoV-2/*genetics, Adult ; COVID-19/diagnosis ; Female ; Humans ; Male ; Mass Screening/methods ; RNA/genetics ; RNA/isolation & purification ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction/methods ; Robotics/methods ; Saliva/chemistry ; Specimen Handling/methods

المؤلفون: Ehrenberg AJ; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Moehle EA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Brook CE; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Doudna Cate AH; University of California, Berkeley, California, United States of America., Witkowsky LB; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Sachdeva R; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hirsh A; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Barry K; Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America., Hamilton JR; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Lin-Shiao E; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., McDevitt S; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Valentin-Alvarado L; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Letourneau KN; University of California, Berkeley, California, United States of America., Hunter L; University of California, Berkeley, California, United States of America., Keller A; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Pestal K; University of California, Berkeley, California, United States of America., Frankino PA; University of California, Berkeley, California, United States of America., Murley A; University of California, Berkeley, California, United States of America., Nandakumar D; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Stahl EC; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Tsuchida CA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Gildea HK; University of California, Berkeley, California, United States of America., Murdock AG; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hochstrasser ML; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., O'Brien E; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Ciling A; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Tsitsiklis A; University of California, Berkeley, California, United States of America., Worden K; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Dugast-Darzacq C; University of California, Berkeley, California, United States of America., Hays SG; University of California, Berkeley, California, United States of America., Barber CC; University of California, Berkeley, California, United States of America., McGarrigle R; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Lam EK; University of California, Berkeley, California, United States of America., Ensminger DC; University of California, Berkeley, California, United States of America., Bardet L; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Sherry C; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Harte A; University of California, Berkeley, California, United States of America.; University Health Services, University of California, Berkeley, California, United States of America., Nicolette G; University of California, Berkeley, California, United States of America.; University Health Services, University of California, Berkeley, California, United States of America., Giannikopoulos P; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Hockemeyer D; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America.; Chan Zuckerberg Biohub, San Francisco, California, United States of America., Petersen M; University of California, Berkeley, California, United States of America., Urnov FD; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Ringeisen BR; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America., Boots M; University of California, Berkeley, California, United States of America., Doudna JA; University of California, Berkeley, California, United States of America.; Innovative Genomics Institute, University of California, Berkeley, California, United States of America.; Howard Hughes Medical Institute, University of California, Berkeley, California, United States of America.

مؤلفون مشاركون: IGI SARS-CoV-2 Testing Consortium

المصدر: PloS one [PLoS One] 2021 May 26; Vol. 16 (5), pp. e0251296. Date of Electronic Publication: 2021 May 26 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Program Evaluation*, COVID-19/*diagnosis , Saliva/*virology, Adult ; Aged ; COVID-19/epidemiology ; COVID-19/virology ; COVID-19 Testing/methods ; Female ; Humans ; Male ; Middle Aged ; RNA, Viral/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Social Norms ; Surveys and Questionnaires ; Universities ; Young Adult

المؤلفون: Stahl EC; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Tsuchida CA; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Hamilton JR; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Lin-Shiao E; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., McDevitt SL; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Moehle EA; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Witkowsky LB; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Tsui CK; University of California, Berkeley, Berkeley, CA, USA., Pestal K; University of California, Berkeley, Berkeley, CA, USA., Gildea HK; University of California, Berkeley, Berkeley, CA, USA., McElroy M; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Keller A; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Sylvain I; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Williams C; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Hirsh A; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Ciling A; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Ehrenberg AJ; University of California, Berkeley, Berkeley, CA, USA., Urnov FD; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Ringeisen BR; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Giannikopoulos P; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA., Doudna JA; University of California, Berkeley, Berkeley, CA, USA.; Innovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA, USA.

مؤلفون مشاركون: IGI SARS-CoV-2 consortium

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2020 Dec 11. Date of Electronic Publication: 2020 Dec 11.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Halpern J; UCSF-UCB Joint Medical Program, School of Public Health, Affiliate Innovative Genomics Institute, University of California, Berkeley, Berkeley, California., O'Hara SE; School of Public Health, Innovative Genomics Institute, University of California, Berkeley, Berkeley, California., Doxzen KW; Innovative Genomics Institute, University of California, Berkeley, Berkeley, California., Witkowsky LB; Innovative Genomics Institute, University of California, Berkeley, Berkeley, California., Owen AL; School of Public Health, Innovative Genomics Institute, University of California, Berkeley, Berkeley, California.

المصدر: The CRISPR journal [CRISPR J] 2019 Oct; Vol. 2 (5), pp. 293-298.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101738191 Publication Model: Print Cited Medium: Internet ISSN: 2573-1602 (Electronic) Linking ISSN: 25731599 NLM ISO Abbreviation: CRISPR J Subsets: MEDLINE

مواضيع طبية MeSH: Gene Editing/*ethics , Human Rights/*ethics, CRISPR-Cas Systems ; Germ Cells ; Humans ; Morals ; Social Values

المؤلفون: Thomsen ND; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; QB3 Institute, University of California, Berkeley, CA 94720., Lawson MR; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; QB3 Institute, University of California, Berkeley, CA 94720., Witkowsky LB; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; QB3 Institute, University of California, Berkeley, CA 94720., Qu S; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.; QB3 Institute, University of California, Berkeley, CA 94720., Berger JM; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720; jmberger@jhmi.edu.; QB3 Institute, University of California, Berkeley, CA 94720.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Nov 29; Vol. 113 (48), pp. E7691-E7700. Date of Electronic Publication: 2016 Nov 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: DNA Helicases/*chemistry , Escherichia coli/*enzymology , Escherichia coli Proteins/*chemistry , Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins/*chemistry, Adenosine Triphosphate/chemistry ; Catalytic Domain ; Hydrolysis ; Kinetics ; Models, Molecular ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Structure, Quaternary ; RNA, Bacterial/chemistry

المؤلفون: Horlbeck MA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Witkowsky LB; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Guglielmi B; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Replogle JM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Gilbert LA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Villalta JE; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Torigoe SE; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Tjian R; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States.

المصدر: ELife [Elife] 2016 Mar 17; Vol. 5. Date of Electronic Publication: 2016 Mar 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*antagonists & inhibitors , DNA/*metabolism , Endonucleases/*antagonists & inhibitors , Nucleosomes/*metabolism, CRISPR-Associated Protein 9 ; Cell Line ; Gene Targeting/methods ; Humans

المؤلفون: Knight SC; Department of Chemistry, University of California, Berkeley, CA, USA., Xie L; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Deng W; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. Transcriptional Imaging Consortium, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Guglielmi B; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Witkowsky LB; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Bosanac L; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Zhang ET; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., El Beheiry M; Laboratoire Physico-Chimie Curie, Institut Curie, Centre National de la Recherche Scientifique UMR 168, Paris, France., Masson JB; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA., Dahan M; Transcriptional Imaging Consortium, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. Laboratoire Physico-Chimie Curie, Institut Curie, Centre National de la Recherche Scientifique UMR 168, Paris, France., Liu Z; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. Transcriptional Imaging Consortium, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. liuz11@janelia.hhmi.org doudna@berkeley.edu jmlim@berkeley.edu., Doudna JA; Department of Chemistry, University of California, Berkeley, CA, USA. Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. Innovative Genomics Initiative, University of California, Berkeley, CA, USA. liuz11@janelia.hhmi.org doudna@berkeley.edu jmlim@berkeley.edu., Tjian R; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. Transcriptional Imaging Consortium, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. Li Ka Shing Biomedical and Health Sciences Center, University of California, Berkeley, CA, USA. liuz11@janelia.hhmi.org doudna@berkeley.edu jmlim@berkeley.edu.

المصدر: Science (New York, N.Y.) [Science] 2015 Nov 13; Vol. 350 (6262), pp. 823-6.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems* , DNA Cleavage* , Genetic Engineering*, Bacterial Proteins/*metabolism , Chromatin/*metabolism , Endonucleases/*metabolism, 3T3 Cells ; Animals ; Bacterial Proteins/chemistry ; CRISPR-Associated Protein 9 ; Chromatin/chemistry ; Chromatin/ultrastructure ; Clustered Regularly Interspaced Short Palindromic Repeats ; Endonucleases/chemistry ; Genome ; Mice ; Single-Cell Analysis